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The map label for this gene is mmgC [H]

Identifier: 187927232

GI number: 187927232

Start: 143431

End: 144561

Strand: Reverse

Name: mmgC [H]

Synonym: Rpic_0124

Alternate gene names: 187927232

Gene position: 144561-143431 (Counterclockwise)

Preceding gene: 187927233

Following gene: 187927231

Centisome position: 3.67

GC content: 65.96

Gene sequence:

>1131_bases
ATGCTGCTGACCCAAGAGCAAGAGATGATTCGCGACGCCATCCGCACCTTCGTGCGCGAGGCGATCGCGCCGCATGCAGC
CGCGTGGGACCGCGATGCGACGTTCCCGAAAGACGTGCACCGCCAACTCGGCGAGCTTGGGGCCTATGGCGTGGCCGTGC
CGGAAGAACTCGGCGGGGCTGGGCTCGACTACCTGTCGCTGGCGCTGATCCTGGAAGAAATTGCTGCCGGCGACGGCGGT
ACCTCCACCGTCATCAGCGTGAACAACTGCCCTGTGTGCAGCATGCTGATGGCGTTTGCGAACGACGCGCAGAAGCAGCA
GTGGCTTGTGCCGCTGGCGCGCGGCGAGATGCTCGGCGCGTTCTGCCTGACCGAGCCGCATGTCGGCTCCGATGCATCGG
CGCTGCGCACCACGGCCGTGCGGGATGGCGACCACTGGGTCCTCAACGGCGTGAAGCAGTTCATCACCAGCGGCAAGCAT
GCCGACGTGGCGATCGTCATGGCCGTGACCGACAAGACCGCAGGCAAGCGCGGCATCAGCGCGTTCCTGGTGCCGACCAA
CACACCGGGCTACATCGTCGCGCGGCTCGAAGACAAGCTTGGCCAGCATTCGTCCGACACGGCGCAGATCGTGTTCGAAG
ACTGCCGCATCCCCGCCGATTGCCTGCTGGGCGAAGAAGGCGCGGGCTACAAGATGGCGCTGTCCGGGCTGGAAGGCGGG
CGCATCGGCATTGCCGCGCAGAGCGTGGGCATGGCGCGTGCGGCCTTTGAAGCCGCGCTGGCATACGCCAAGGAGCGCGA
AAGCTTTGGCCAGCCGCTGTTTGCGCACCAGGCCGTGCAGTTTCGGCTGGCAGAGATGGCGACGCGCGTGGATGTGGCGC
GGCAGATGGTCTGGCATGCCGCCAGCCTGAAAGACGCCGGGCTGCCGTGCCTGAAAGAGGCGGCCATGGCCAAGCTCAAC
GCCAGCGAGATGGCCGAGCGCGTGTGCTCCGATGCCATCCAGGTCTTTGGCGGTTACGGCTATGTCAGCGACTTCCCGGT
GGAGCGCATCTACCGCGACGTGCGCGTGTGCCAGATCTACGAAGGCACGAGCGATATCCAGAAAATCTTGATCGCCCGCG
CGCTGGCGTAG

Upstream 100 bases:

>100_bases
GTGGCTGGCATCCGCCGCGTGATCGCCGGCGCCACGCGCGCCGACAACGGCGGGTTCCGCAACTACGACGGCAGCGTCAT
TGAATGGTGAGGCCGGAACG

Downstream 100 bases:

>100_bases
GCAGTTTTGGGAAAGGCGCAGCACAACAAGGGGAGCACACCATGAACGGGGCCATCGATTTCTACTTCGACTTCTCGTCG
CCGTACGGCTACTTCGCCAG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MLLTQEQEMIRDAIRTFVREAIAPHAAAWDRDATFPKDVHRQLGELGAYGVAVPEELGGAGLDYLSLALILEEIAAGDGG
TSTVISVNNCPVCSMLMAFANDAQKQQWLVPLARGEMLGAFCLTEPHVGSDASALRTTAVRDGDHWVLNGVKQFITSGKH
ADVAIVMAVTDKTAGKRGISAFLVPTNTPGYIVARLEDKLGQHSSDTAQIVFEDCRIPADCLLGEEGAGYKMALSGLEGG
RIGIAAQSVGMARAAFEAALAYAKERESFGQPLFAHQAVQFRLAEMATRVDVARQMVWHAASLKDAGLPCLKEAAMAKLN
ASEMAERVCSDAIQVFGGYGYVSDFPVERIYRDVRVCQIYEGTSDIQKILIARALA

Sequences:

>Translated_376_residues
MLLTQEQEMIRDAIRTFVREAIAPHAAAWDRDATFPKDVHRQLGELGAYGVAVPEELGGAGLDYLSLALILEEIAAGDGG
TSTVISVNNCPVCSMLMAFANDAQKQQWLVPLARGEMLGAFCLTEPHVGSDASALRTTAVRDGDHWVLNGVKQFITSGKH
ADVAIVMAVTDKTAGKRGISAFLVPTNTPGYIVARLEDKLGQHSSDTAQIVFEDCRIPADCLLGEEGAGYKMALSGLEGG
RIGIAAQSVGMARAAFEAALAYAKERESFGQPLFAHQAVQFRLAEMATRVDVARQMVWHAASLKDAGLPCLKEAAMAKLN
ASEMAERVCSDAIQVFGGYGYVSDFPVERIYRDVRVCQIYEGTSDIQKILIARALA
>Mature_376_residues
MLLTQEQEMIRDAIRTFVREAIAPHAAAWDRDATFPKDVHRQLGELGAYGVAVPEELGGAGLDYLSLALILEEIAAGDGG
TSTVISVNNCPVCSMLMAFANDAQKQQWLVPLARGEMLGAFCLTEPHVGSDASALRTTAVRDGDHWVLNGVKQFITSGKH
ADVAIVMAVTDKTAGKRGISAFLVPTNTPGYIVARLEDKLGQHSSDTAQIVFEDCRIPADCLLGEEGAGYKMALSGLEGG
RIGIAAQSVGMARAAFEAALAYAKERESFGQPLFAHQAVQFRLAEMATRVDVARQMVWHAASLKDAGLPCLKEAAMAKLN
ASEMAERVCSDAIQVFGGYGYVSDFPVERIYRDVRVCQIYEGTSDIQKILIARALA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=48.1081081081081, Blast_Score=361, Evalue=1e-100,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=40.2144772117962, Blast_Score=298, Evalue=5e-81,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=39.5225464190981, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=37.6657824933687, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=37.9679144385027, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=37.9679144385027, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=38.1231671554252, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=35.9042553191489, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI76496475, Length=338, Percent_Identity=37.2781065088757, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI21361497, Length=351, Percent_Identity=35.8974358974359, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI4557235, Length=338, Percent_Identity=37.2781065088757, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=29.1777188328912, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=28.7292817679558, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI38505218, Length=331, Percent_Identity=32.3262839879154, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI48976061, Length=339, Percent_Identity=30.3834808259587, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI211971008, Length=339, Percent_Identity=30.3834808259587, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI87081958, Length=375, Percent_Identity=32, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=29.144385026738, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87082384, Length=319, Percent_Identity=29.7805642633229, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI87081702, Length=367, Percent_Identity=24.7956403269755, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=374, Percent_Identity=37.4331550802139, Blast_Score=280, Evalue=8e-76,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=38.8140161725067, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17569725, Length=376, Percent_Identity=36.968085106383, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17534899, Length=379, Percent_Identity=36.6754617414248, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=37.7659574468085, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=36.7021276595745, Blast_Score=260, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=33.8666666666667, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=38.2252559726962, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=37.1428571428571, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17551932, Length=377, Percent_Identity=30.7692307692308, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=30.5039787798408, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=38.695652173913, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=32.1033210332103, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71985192, Length=297, Percent_Identity=35.3535353535354, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=28.1914893617021, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=34.4398340248963, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17562446, Length=347, Percent_Identity=28.8184438040346, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17531913, Length=177, Percent_Identity=34.4632768361582, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=276, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=276, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=46.112600536193, Blast_Score=356, Evalue=1e-98,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=45.0402144772118, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=39.3048128342246, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=38.1962864721485, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=35.1851851851852, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI281363737, Length=381, Percent_Identity=34.6456692913386, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI19920834, Length=377, Percent_Identity=30.7692307692308, Blast_Score=174, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40395; Mature: 40395

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTQEQEMIRDAIRTFVREAIAPHAAAWDRDATFPKDVHRQLGELGAYGVAVPEELGGA
CCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCC
GLDYLSLALILEEIAAGDGGTSTVISVNNCPVCSMLMAFANDAQKQQWLVPLARGEMLGA
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHEEEHHCCCHHHH
FCLTEPHVGSDASALRTTAVRDGDHWVLNGVKQFITSGKHADVAIVMAVTDKTAGKRGIS
HCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCE
AFLVPTNTPGYIVARLEDKLGQHSSDTAQIVFEDCRIPADCLLGEEGAGYKMALSGLEGG
EEEEECCCCCEEEEEEHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCEEEECCCCCC
RIGIAAQSVGMARAAFEAALAYAKERESFGQPLFAHQAVQFRLAEMATRVDVARQMVWHA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLKDAGLPCLKEAAMAKLNASEMAERVCSDAIQVFGGYGYVSDFPVERIYRDVRVCQIY
HHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEE
EGTSDIQKILIARALA
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLTQEQEMIRDAIRTFVREAIAPHAAAWDRDATFPKDVHRQLGELGAYGVAVPEELGGA
CCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCC
GLDYLSLALILEEIAAGDGGTSTVISVNNCPVCSMLMAFANDAQKQQWLVPLARGEMLGA
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHEEEHHCCCHHHH
FCLTEPHVGSDASALRTTAVRDGDHWVLNGVKQFITSGKHADVAIVMAVTDKTAGKRGIS
HCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCE
AFLVPTNTPGYIVARLEDKLGQHSSDTAQIVFEDCRIPADCLLGEEGAGYKMALSGLEGG
EEEEECCCCCEEEEEEHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCEEEECCCCCC
RIGIAAQSVGMARAAFEAALAYAKERESFGQPLFAHQAVQFRLAEMATRVDVARQMVWHA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLKDAGLPCLKEAAMAKLNASEMAERVCSDAIQVFGGYGYVSDFPVERIYRDVRVCQIY
HHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEE
EGTSDIQKILIARALA
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]