Click here to switch to the map view.

The map label for this gene is csgA [H]

Identifier: 187927233

GI number: 187927233

Start: 144572

End: 145285

Strand: Reverse

Name: csgA [H]

Synonym: Rpic_0125

Alternate gene names: 187927233

Gene position: 145285-144572 (Counterclockwise)

Preceding gene: 187927234

Following gene: 187927232

Centisome position: 3.69

GC content: 69.19

Gene sequence:

>714_bases
ATGACGAACGCAACGTCCCGCCGCACGCGCACCGCGCTCATCCTGGGCGCGTCGCGCGGCATCGGCCTGGAAACGGTCAA
GCAGTATCGCGCGGATGGCTGGCGCGTGATTGCCACCGTGCGCACGCAAGAAGCAGCGCACGCACTGCAGGCATTGGGCG
CTGAAACGCATGTGCTGGACCTGACCGACGCCAACGCCGTCGCCGGCCTCGCGTGGAAGCTCGACGGCGAAGCGCTGGAC
GTGGCGATCTACGTGGCGGGCATCTACGGCCCGCGCACGCAGGGTGCCACGCCCGTCAGCCAGGCCGACTTTGATGCCGT
GATGCACACCAACGTGTGGGCCCCGATGGGCGTGCTGCCCGCCGTGCTGCCGATGGTGGAAGCCGGACGCAATGGTGCGG
ACGAGCCTGGCGGCGTGCTCGCCGTCATCTCCAGCCGCATGGGCAGCATCGGCGACATGGCGGGCAACGGCGGCTGGCTG
TATCGCGCGAGCAAGGCGGCGGTGAATGCCGTATTGCGCGGGGTGTCGATCGACGCCAAGAACGCCACGTGCCTGACGTT
CCACCCCGGTTGGGTACAGACCGACATGGGCGGCGCGGACGCGGCCATCACGCCGCAGGAGAGTGTGGCTGGCATCCGCC
GCGTGATCGCCGGCGCCACGCGCGCCGACAACGGCGGGTTCCGCAACTACGACGGCAGCGTCATTGAATGGTGA

Upstream 100 bases:

>100_bases
CGCGCTGCAACACCGTGGCGGCAAGCGCGGTGTGGCCAGCCTGTGCATCGGCGGCGGTGAAGCCACGGCCGTCGGCATCG
AACTCTACTAAGGCACGCGC

Downstream 100 bases:

>100_bases
GGCCGGAACGATGCTGCTGACCCAAGAGCAAGAGATGATTCGCGACGCCATCCGCACCTTCGTGCGCGAGGCGATCGCGC
CGCATGCAGCCGCGTGGGAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTNATSRRTRTALILGASRGIGLETVKQYRADGWRVIATVRTQEAAHALQALGAETHVLDLTDANAVAGLAWKLDGEALD
VAIYVAGIYGPRTQGATPVSQADFDAVMHTNVWAPMGVLPAVLPMVEAGRNGADEPGGVLAVISSRMGSIGDMAGNGGWL
YRASKAAVNAVLRGVSIDAKNATCLTFHPGWVQTDMGGADAAITPQESVAGIRRVIAGATRADNGGFRNYDGSVIEW

Sequences:

>Translated_237_residues
MTNATSRRTRTALILGASRGIGLETVKQYRADGWRVIATVRTQEAAHALQALGAETHVLDLTDANAVAGLAWKLDGEALD
VAIYVAGIYGPRTQGATPVSQADFDAVMHTNVWAPMGVLPAVLPMVEAGRNGADEPGGVLAVISSRMGSIGDMAGNGGWL
YRASKAAVNAVLRGVSIDAKNATCLTFHPGWVQTDMGGADAAITPQESVAGIRRVIAGATRADNGGFRNYDGSVIEW
>Mature_236_residues
TNATSRRTRTALILGASRGIGLETVKQYRADGWRVIATVRTQEAAHALQALGAETHVLDLTDANAVAGLAWKLDGEALDV
AIYVAGIYGPRTQGATPVSQADFDAVMHTNVWAPMGVLPAVLPMVEAGRNGADEPGGVLAVISSRMGSIGDMAGNGGWLY
RASKAAVNAVLRGVSIDAKNATCLTFHPGWVQTDMGGADAAITPQESVAGIRRVIAGATRADNGGFRNYDGSVIEW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI193207563, Length=240, Percent_Identity=32.5, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17558996, Length=249, Percent_Identity=28.1124497991968, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17558994, Length=241, Percent_Identity=30.2904564315353, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559964, Length=250, Percent_Identity=31.2, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558992, Length=243, Percent_Identity=30.8641975308642, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559962, Length=245, Percent_Identity=31.0204081632653, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558990, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322779, Length=268, Percent_Identity=28.7313432835821, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640547, Length=244, Percent_Identity=32.3770491803279, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24685; Mature: 24554

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNATSRRTRTALILGASRGIGLETVKQYRADGWRVIATVRTQEAAHALQALGAETHVLD
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEEEHHHHHHHHHHCCCCCEEEE
LTDANAVAGLAWKLDGEALDVAIYVAGIYGPRTQGATPVSQADFDAVMHTNVWAPMGVLP
ECCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHH
AVLPMVEAGRNGADEPGGVLAVISSRMGSIGDMAGNGGWLYRASKAAVNAVLRGVSIDAK
HHHHHHHCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHCCEEECC
NATCLTFHPGWVQTDMGGADAAITPQESVAGIRRVIAGATRADNGGFRNYDGSVIEW
CCEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
TNATSRRTRTALILGASRGIGLETVKQYRADGWRVIATVRTQEAAHALQALGAETHVLD
CCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEEEHHHHHHHHHHCCCCCEEEE
LTDANAVAGLAWKLDGEALDVAIYVAGIYGPRTQGATPVSQADFDAVMHTNVWAPMGVLP
ECCCCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHH
AVLPMVEAGRNGADEPGGVLAVISSRMGSIGDMAGNGGWLYRASKAAVNAVLRGVSIDAK
HHHHHHHCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHCCEEECC
NATCLTFHPGWVQTDMGGADAAITPQESVAGIRRVIAGATRADNGGFRNYDGSVIEW
CCEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]