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The map label for this gene is mmgC [H]

Identifier: 187927212

GI number: 187927212

Start: 121371

End: 122525

Strand: Direct

Name: mmgC [H]

Synonym: Rpic_0104

Alternate gene names: 187927212

Gene position: 121371-122525 (Clockwise)

Preceding gene: 187927211

Following gene: 187927213

Centisome position: 3.08

GC content: 65.45

Gene sequence:

>1155_bases
ATGCTTTCAGGTTTGCTCCCGTCTGCCCGCTTCGATGCCGATCACGATACCTTTCGCGAGACGGTGCGCCGCTTTGTCGA
CAAGGCCGTGCTGCCGCACATCGATGCGTGGGAAGAGGCCGAGACGTTTCCGCGTGCGCTGTATCGCGAAGCGGCCGACC
TTGGCTTGCTCGGCATTGGTTTCCCCGAGGAATACGGTGGCACGCCGGGCGACCTGTTTCTTGAACTGGCGATGATCGAA
GAGCTGACGCGAGCGGCCAGCGGCGGTCTACTCGCATCGCTGTTCAGCCATACGATCGGTGCGCCGCCCATCGTGGCGGG
CGGATCGGCCGAGCTGAAGGCGCGCGTGTTGCCGGCGATTCTGTCGGGCGAGAAGATCAGCGCGCTTGCCATCACCGAGC
CTTCGGGCGGCTCGGATGTCGCCAGCCTCACCACACGCGCGGTGCGCGACGGCGATCACTACGTCGTCTCCGGCAGCAAG
ATCTTCATCACCTCCGGCATGCGCGCCGATTACATCACCGTGGCCGTGCGCACCGGCGAGGCGGGCGCGGGCGGCATCTC
CGTGCTGCTGGTGGAGGGCGATACGCCTGGGCTGTCGCGCACGCCGCTCAAGAAGATGGGCTGGTGGTGCTCTGACACGG
CGCAACTGCATTTCGACAACTGCCGCGTGCCGGTCGGCAACCTGCTCGGCGCGGAAAACCGCGGTTTCGAGCTGGTGATG
CGCAACTTCAACCACGAACGCCTCGCGCTGGCGATGCAGGCCTACGGCCTGGCGCGCACGTGTCTGATCGAAGCCGTGGA
ATGGGCCACCCAGCGCGAGACCTTCGGCAAGCGCCTCGTGCAGCACCAGGTGGCGCGCCAGAAGCTGGTGGCGATGGCCA
CGCGCATCGAAGCCACCCGGGCGTTGCTGGAAGACCTGATGCGGCGCATGCAGGCCGGCGATTCTCCGGTCGCGCAGCTG
TGCATGCTGAAAAATTTCGCAACGCAGAGCTTGCAGTTCTGCGCGGACACGGCCGTGCAACTGCTTGGCGGTATGGGCTT
CATGCGCGGCACCAAGTCGGAGCGCATCTATCGTGAAGTGAAGGTCTACATGATCGGCGGCGGCGCGGAGGAAGTTCTCA
GCGACCTTGCCGCGCGCCAACTCGGCTGGACCTAA

Upstream 100 bases:

>100_bases
CATCGCTGCGCAATGATCCGCTCGGCAAGGGCATGGCGCAGGTGCTGCTGACGATGCCGGTGCGCGTGCCGGTCAACCAC
CCTTGATTGACGAGGCGATC

Downstream 100 bases:

>100_bases
CGCGCATTCAGGGAGAGAACCATGTATCGCTCAGTCTTTCGACCGGGGCTGTTCCAGGGGCAGGTGGCCGTGGTGACGGG
TGGCGGCAGCGGCATCGGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MLSGLLPSARFDADHDTFRETVRRFVDKAVLPHIDAWEEAETFPRALYREAADLGLLGIGFPEEYGGTPGDLFLELAMIE
ELTRAASGGLLASLFSHTIGAPPIVAGGSAELKARVLPAILSGEKISALAITEPSGGSDVASLTTRAVRDGDHYVVSGSK
IFITSGMRADYITVAVRTGEAGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNCRVPVGNLLGAENRGFELVM
RNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGKRLVQHQVARQKLVAMATRIEATRALLEDLMRRMQAGDSPVAQL
CMLKNFATQSLQFCADTAVQLLGGMGFMRGTKSERIYREVKVYMIGGGAEEVLSDLAARQLGWT

Sequences:

>Translated_384_residues
MLSGLLPSARFDADHDTFRETVRRFVDKAVLPHIDAWEEAETFPRALYREAADLGLLGIGFPEEYGGTPGDLFLELAMIE
ELTRAASGGLLASLFSHTIGAPPIVAGGSAELKARVLPAILSGEKISALAITEPSGGSDVASLTTRAVRDGDHYVVSGSK
IFITSGMRADYITVAVRTGEAGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNCRVPVGNLLGAENRGFELVM
RNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGKRLVQHQVARQKLVAMATRIEATRALLEDLMRRMQAGDSPVAQL
CMLKNFATQSLQFCADTAVQLLGGMGFMRGTKSERIYREVKVYMIGGGAEEVLSDLAARQLGWT
>Mature_384_residues
MLSGLLPSARFDADHDTFRETVRRFVDKAVLPHIDAWEEAETFPRALYREAADLGLLGIGFPEEYGGTPGDLFLELAMIE
ELTRAASGGLLASLFSHTIGAPPIVAGGSAELKARVLPAILSGEKISALAITEPSGGSDVASLTTRAVRDGDHYVVSGSK
IFITSGMRADYITVAVRTGEAGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNCRVPVGNLLGAENRGFELVM
RNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGKRLVQHQVARQKLVAMATRIEATRALLEDLMRRMQAGDSPVAQL
CMLKNFATQSLQFCADTAVQLLGGMGFMRGTKSERIYREVKVYMIGGGAEEVLSDLAARQLGWT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=35.4666666666667, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI7656849, Length=383, Percent_Identity=32.1148825065274, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI226958412, Length=362, Percent_Identity=31.2154696132597, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=31.8537859007833, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=31.8537859007833, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=32, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=29.1777188328912, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=33.0666666666667, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=32.6086956521739, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI76496475, Length=373, Percent_Identity=31.3672922252011, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557235, Length=373, Percent_Identity=31.3672922252011, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI7669494, Length=350, Percent_Identity=28.8571428571429, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI4503943, Length=350, Percent_Identity=28.8571428571429, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI38505218, Length=288, Percent_Identity=29.8611111111111, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI48976061, Length=282, Percent_Identity=27.3049645390071, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI211971008, Length=282, Percent_Identity=27.3049645390071, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081958, Length=343, Percent_Identity=30.6122448979592, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786223, Length=332, Percent_Identity=28.3132530120482, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI87082384, Length=264, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=34.8648648648649, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=31.0160427807487, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=31.404958677686, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=31.9559228650138, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=31.6489361702128, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=386, Percent_Identity=30.3108808290155, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=346, Percent_Identity=34.971098265896, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=30.8900523560209, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=30.7692307692308, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17533517, Length=381, Percent_Identity=29.9212598425197, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=35.0877192982456, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=33.4532374100719, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=33.9130434782609, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=28.3154121863799, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17534353, Length=345, Percent_Identity=26.3768115942029, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=236, Percent_Identity=25.8474576271186, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=290, Percent_Identity=25.5172413793103, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=33.42175066313, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24660351, Length=375, Percent_Identity=30.6666666666667, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=31.129476584022, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI21356377, Length=361, Percent_Identity=29.6398891966759, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24646207, Length=386, Percent_Identity=31.0880829015544, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281363737, Length=333, Percent_Identity=32.1321321321321, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI19920834, Length=284, Percent_Identity=29.5774647887324, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41593; Mature: 41593

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGLLPSARFDADHDTFRETVRRFVDKAVLPHIDAWEEAETFPRALYREAADLGLLGIG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEECC
FPEEYGGTPGDLFLELAMIEELTRAASGGLLASLFSHTIGAPPIVAGGSAELKARVLPAI
CCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHH
LSGEKISALAITEPSGGSDVASLTTRAVRDGDHYVVSGSKIFITSGMRADYITVAVRTGE
HCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCEEEEEEEECC
AGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNCRVPVGNLLGAENRGFELVM
CCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHCCCCCCCHHHHH
RNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGKRLVQHQVARQKLVAMATRIEATR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLEDLMRRMQAGDSPVAQLCMLKNFATQSLQFCADTAVQLLGGMGFMRGTKSERIYREV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHEEE
KVYMIGGGAEEVLSDLAARQLGWT
EEEEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSGLLPSARFDADHDTFRETVRRFVDKAVLPHIDAWEEAETFPRALYREAADLGLLGIG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEECC
FPEEYGGTPGDLFLELAMIEELTRAASGGLLASLFSHTIGAPPIVAGGSAELKARVLPAI
CCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHH
LSGEKISALAITEPSGGSDVASLTTRAVRDGDHYVVSGSKIFITSGMRADYITVAVRTGE
HCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCEEEEEEEECC
AGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNCRVPVGNLLGAENRGFELVM
CCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHCCCCCCCHHHHH
RNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGKRLVQHQVARQKLVAMATRIEATR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLEDLMRRMQAGDSPVAQLCMLKNFATQSLQFCADTAVQLLGGMGFMRGTKSERIYREV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHEEE
KVYMIGGGAEEVLSDLAARQLGWT
EEEEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]