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The map label for this gene is murB [H]

Identifier: 187935675

GI number: 187935675

Start: 3520822

End: 3521736

Strand: Reverse

Name: murB [H]

Synonym: CLL_A3343

Alternate gene names: 187935675

Gene position: 3521736-3520822 (Counterclockwise)

Preceding gene: 187934936

Following gene: 187932869

Centisome position: 92.67

GC content: 30.27

Gene sequence:

>915_bases
ATGAATCAAAATAAAAACTATAGAGTTTTATTTAGCAATTTATACAAAGATACACAAATGCAAGAAAATGCAAAAATGAG
TGAACATATAAATTTTAGAGTTGGGGGACCAGTAGATATACTTTTAACTCCAAATACTAAAGAACAAATAGTAGAAACAA
TAAATATATGTAAAGAAAATAAGATACCTTTTTATGTTCTAGGAAATGGATCTAATGTCTTAGTTAAAGATTCTGGAATA
AGAGGCGTTGTTATAAAGTTATCCGAATTTGATAATATAGTTAGAGATGGAAATACAATAAAAGCAGAAAGTGGTGCGCT
ATTAAAAGATGTATCAGCTGAAGCTTTGAAAGCATCATTAACTGGATTTGAATTTGCTTGTGGAATTCCAGGCAGTGTGG
GCGGAGCTGTATTTATGAATGCAGGTGCTTATGATGGAGAAATTTCTTTTGTAATTAAAGAAGCAGAAGTTATGAGTGAA
GATGGAAAGATAATAACTCTATCAAAAGATCAATTAGAGTTAGGATATAGAACATCAGCAATAATGAAAAAAAATTATAT
AGTAATAACTGCTACGTTCTGTTTTGAATCTGGAGAAAAAGATAAAATTGAAGGACGAGTATCTGAGTTAACAAATAAAA
GAGAAGAAAAGCAACCTTTAGAATTTCCATCTGCAGGTAGTACATTTAAAAGACCAGAAGGCCACTTTGCGGGAAAATTA
ATTCAGGATGCTGGATTAAAAGATTTCACTTTAGGTGGGGCAGCTGTATCAGGCAAACATTGTGGATTTATAATAAATAA
ATCTAATGCTACAGCTAAAGATATTTTAGACTTAATAGAATATATTCAAAAAGAAGTAAAGAAACAATTTGGTGTGGATT
TATATCCAGAAGTTAGAATAATAGGTGAAGACTAA

Upstream 100 bases:

>100_bases
TTTTAAAAAACATGAACATAATTCGTAATTTATGCTATAATAATACGGAAATAATAATATTTACTTAAAAAATCAATATA
AGTATTTGAGGAGTTTTATC

Downstream 100 bases:

>100_bases
TCATATAATATTTAAAAAATAAAGAACTCAAAAGCATTAATGCTTTTGAGTTCTTTATTTTTTAAAATTTTATATTGGAA
TTTTTAAAGTATATATTTAG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNQNKNYRVLFSNLYKDTQMQENAKMSEHINFRVGGPVDILLTPNTKEQIVETINICKENKIPFYVLGNGSNVLVKDSGI
RGVVIKLSEFDNIVRDGNTIKAESGALLKDVSAEALKASLTGFEFACGIPGSVGGAVFMNAGAYDGEISFVIKEAEVMSE
DGKIITLSKDQLELGYRTSAIMKKNYIVITATFCFESGEKDKIEGRVSELTNKREEKQPLEFPSAGSTFKRPEGHFAGKL
IQDAGLKDFTLGGAAVSGKHCGFIINKSNATAKDILDLIEYIQKEVKKQFGVDLYPEVRIIGED

Sequences:

>Translated_304_residues
MNQNKNYRVLFSNLYKDTQMQENAKMSEHINFRVGGPVDILLTPNTKEQIVETINICKENKIPFYVLGNGSNVLVKDSGI
RGVVIKLSEFDNIVRDGNTIKAESGALLKDVSAEALKASLTGFEFACGIPGSVGGAVFMNAGAYDGEISFVIKEAEVMSE
DGKIITLSKDQLELGYRTSAIMKKNYIVITATFCFESGEKDKIEGRVSELTNKREEKQPLEFPSAGSTFKRPEGHFAGKL
IQDAGLKDFTLGGAAVSGKHCGFIINKSNATAKDILDLIEYIQKEVKKQFGVDLYPEVRIIGED
>Mature_304_residues
MNQNKNYRVLFSNLYKDTQMQENAKMSEHINFRVGGPVDILLTPNTKEQIVETINICKENKIPFYVLGNGSNVLVKDSGI
RGVVIKLSEFDNIVRDGNTIKAESGALLKDVSAEALKASLTGFEFACGIPGSVGGAVFMNAGAYDGEISFVIKEAEVMSE
DGKIITLSKDQLELGYRTSAIMKKNYIVITATFCFESGEKDKIEGRVSELTNKREEKQPLEFPSAGSTFKRPEGHFAGKL
IQDAGLKDFTLGGAAVSGKHCGFIINKSNATAKDILDLIEYIQKEVKKQFGVDLYPEVRIIGED

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33368; Mature: 33368

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQNKNYRVLFSNLYKDTQMQENAKMSEHINFRVGGPVDILLTPNTKEQIVETINICKEN
CCCCCCEEEEEEHHHHHHHHHHCCCHHHCEEEEECCCEEEEECCCCHHHHHHHHHHHHCC
KIPFYVLGNGSNVLVKDSGIRGVVIKLSEFDNIVRDGNTIKAESGALLKDVSAEALKASL
CCCEEEEECCCEEEEECCCCCEEEEEEHHHHHHHHCCCEEEECCCCHHHHCCHHHHHHHC
TGFEFACGIPGSVGGAVFMNAGAYDGEISFVIKEAEVMSEDGKIITLSKDQLELGYRTSA
CCEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEHHHHCCCCCEEEEECCCCCCCCCHHH
IMKKNYIVITATFCFESGEKDKIEGRVSELTNKREEKQPLEFPSAGSTFKRPEGHFAGKL
EEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
IQDAGLKDFTLGGAAVSGKHCGFIINKSNATAKDILDLIEYIQKEVKKQFGVDLYPEVRI
HHHCCCCEEECCCCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IGED
EECC
>Mature Secondary Structure
MNQNKNYRVLFSNLYKDTQMQENAKMSEHINFRVGGPVDILLTPNTKEQIVETINICKEN
CCCCCCEEEEEEHHHHHHHHHHCCCHHHCEEEEECCCEEEEECCCCHHHHHHHHHHHHCC
KIPFYVLGNGSNVLVKDSGIRGVVIKLSEFDNIVRDGNTIKAESGALLKDVSAEALKASL
CCCEEEEECCCEEEEECCCCCEEEEEEHHHHHHHHCCCEEEECCCCHHHHCCHHHHHHHC
TGFEFACGIPGSVGGAVFMNAGAYDGEISFVIKEAEVMSEDGKIITLSKDQLELGYRTSA
CCEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEHHHHCCCCCEEEEECCCCCCCCCHHH
IMKKNYIVITATFCFESGEKDKIEGRVSELTNKREEKQPLEFPSAGSTFKRPEGHFAGKL
EEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
IQDAGLKDFTLGGAAVSGKHCGFIINKSNATAKDILDLIEYIQKEVKKQFGVDLYPEVRI
HHHCCCCEEECCCCEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IGED
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA