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The map label for this gene is uvrC [H]

Identifier: 187934936

GI number: 187934936

Start: 3521809

End: 3523689

Strand: Reverse

Name: uvrC [H]

Synonym: CLL_A3344

Alternate gene names: 187934936

Gene position: 3523689-3521809 (Counterclockwise)

Preceding gene: 187933516

Following gene: 187935675

Centisome position: 92.72

GC content: 26.9

Gene sequence:

>1881_bases
ATGATAATATTTGACTTTAAAAATCAACTTAAAATTTTACCAGATGAGCCAGGGGTATATTTAATGAAAAATTCCCTTGG
AGAAGTCATTTACGTGGGAAAAGCAAAAATACTTAAAAACAGAGTAAGACAATACTTTCAAAATTCAAAAAATCATTCTG
AAAAAGTAAAAGCTATGGTAAAAAATATTTCAGAGTTTGAATATATAATCACTGACTCAGAAATGGAAGCATTAATATTA
GAATGTAATCTAATAAAAAAATATAGTCCAAGATATAACATACTTTTAAAGGATGATAAGTTTTACCCATTTATAAAAGT
TACTATAAATGAAGAATTCCCCAAAATCTTTATTACTAGAAAATATGCTAAAGATGGTAATAAATATTTTGGACCATACA
CTAATATAGCTTCTGTTTATGAAACTATGAACTTAATAAAAAAGATATTTCCAATAAGAACATGTAAGAAAACTATAACA
GAAGGTGGTAATCCAACTAGACCATGTTTAAATTATCATATAAAAAAATGCAATGCACCGTGTGCAGGATATATATCTAA
AGATGAATATAGAAATATGATAAGTGAAGTAATGGAACTTTTAAGTGGAAAGAATAAAGACTTAGTGAATAAACTTCAAA
AAGATATGGAGGACGCTTCAAAAAGCTTAGAATTTGAAAAGGCAGCTTCATTGAGAGATAAAATAATAGCTATAAATAAT
ATAGTAGAAAAACAAAAAGTCTTTAAATCACAAGAAGGAGACGAAGATTTTATCAATTTGTATAAAGATGAAAAAGATTG
TTGTGTTCAAGTATTCTTTCTTAGAGATGGAAAAGTTACCGGCAGGGAACATTTTATATTGGAAAATAGTACATATCAAG
AGGAAAGTAGTATTCTATCTCAGTTTATGATTTCTTTTTATGGGGGAACGCCTAAAGTACCTAAACATATTTATATCCCT
AAGGAACAAGATACTGAAATTTTAGAAGAATTTTTAAAGATAAAAAGAGGTTCTAAAGTTAATGTTAAAGTACCTAAAAA
GGGAAGTAAAAAAGAAATGTTAGAATTAGTAAAAAATAATGCAAAGCTTACTCTAGAACAATTTAAAGAAAAGCTATTAA
TGGACAAGAAAATAAATAGAGGATGCTTAGAAGAACTGAAGGAACTTTTAAATTTAGATGATATACCAAATAGAATAGAG
TCTTTTGATATATCTAACATACAAGGTGTAGATTCAGTTGGTTCTATGATAGTTTTTGAAAATGGAAAAGCCAAGAATAG
TGATTACAGAAGATTTAGTATAAAAAATGTTAAAAATGGAAATGAATATGATAGCATGAGAGAAATTTTAGAGAGAAGAT
TTGTTCATGGATTAAAAGAAGTAAAGGAAATACAAGAGAGAAATCTTCAATTTTCAAATGGAAAGTTTTCTAATTTTCCA
GATCTAATTATGATGGATGGTGGAAAAGGTCAAGTTAATGTAGCTAAAGAGGTATTAAATAAGTTGGATATACAGATACC
TGTATGTGGATTAGTTAAAGATGATCGCCATTCAACTAGAGGGATTATTTATAATAATGAAGAGATTATTATAAATAGAA
GCTCAAATCTTATGCAATTTATAAGAAGAGTACAAGATGAAGTTCATAGATTCGCAATAACATATCATAGAAGTTTAAGA
GATAAGAGGACACTACATTCAATATTAGAAGATATACCTAATATTGGTGAAAAAAGAAGAAGAGCATTACTTATGAAATT
TGGAAGTGTTGAGAATATAAAAAATGCTAAATTAGAAGAATTATTATCTACAGAATCCATAGATAATAAGGCTGCAGAGA
GTATTATATCTTATTTTAAAAAACATGAACATAATTCGTAA

Upstream 100 bases:

>100_bases
TCTTAGACATAGCGTTAATTAAATGTTGATATTGTAATATCGATAGTATATTATAATATCAACATTATTAGAATACATAG
AAATATAATTTGCGGAGGTG

Downstream 100 bases:

>100_bases
TTTATGCTATAATAATACGGAAATAATAATATTTACTTAAAAAATCAATATAAGTATTTGAGGAGTTTTATCATGAATCA
AAATAAAAACTATAGAGTTT

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MIIFDFKNQLKILPDEPGVYLMKNSLGEVIYVGKAKILKNRVRQYFQNSKNHSEKVKAMVKNISEFEYIITDSEMEALIL
ECNLIKKYSPRYNILLKDDKFYPFIKVTINEEFPKIFITRKYAKDGNKYFGPYTNIASVYETMNLIKKIFPIRTCKKTIT
EGGNPTRPCLNYHIKKCNAPCAGYISKDEYRNMISEVMELLSGKNKDLVNKLQKDMEDASKSLEFEKAASLRDKIIAINN
IVEKQKVFKSQEGDEDFINLYKDEKDCCVQVFFLRDGKVTGREHFILENSTYQEESSILSQFMISFYGGTPKVPKHIYIP
KEQDTEILEEFLKIKRGSKVNVKVPKKGSKKEMLELVKNNAKLTLEQFKEKLLMDKKINRGCLEELKELLNLDDIPNRIE
SFDISNIQGVDSVGSMIVFENGKAKNSDYRRFSIKNVKNGNEYDSMREILERRFVHGLKEVKEIQERNLQFSNGKFSNFP
DLIMMDGGKGQVNVAKEVLNKLDIQIPVCGLVKDDRHSTRGIIYNNEEIIINRSSNLMQFIRRVQDEVHRFAITYHRSLR
DKRTLHSILEDIPNIGEKRRRALLMKFGSVENIKNAKLEELLSTESIDNKAAESIISYFKKHEHNS

Sequences:

>Translated_626_residues
MIIFDFKNQLKILPDEPGVYLMKNSLGEVIYVGKAKILKNRVRQYFQNSKNHSEKVKAMVKNISEFEYIITDSEMEALIL
ECNLIKKYSPRYNILLKDDKFYPFIKVTINEEFPKIFITRKYAKDGNKYFGPYTNIASVYETMNLIKKIFPIRTCKKTIT
EGGNPTRPCLNYHIKKCNAPCAGYISKDEYRNMISEVMELLSGKNKDLVNKLQKDMEDASKSLEFEKAASLRDKIIAINN
IVEKQKVFKSQEGDEDFINLYKDEKDCCVQVFFLRDGKVTGREHFILENSTYQEESSILSQFMISFYGGTPKVPKHIYIP
KEQDTEILEEFLKIKRGSKVNVKVPKKGSKKEMLELVKNNAKLTLEQFKEKLLMDKKINRGCLEELKELLNLDDIPNRIE
SFDISNIQGVDSVGSMIVFENGKAKNSDYRRFSIKNVKNGNEYDSMREILERRFVHGLKEVKEIQERNLQFSNGKFSNFP
DLIMMDGGKGQVNVAKEVLNKLDIQIPVCGLVKDDRHSTRGIIYNNEEIIINRSSNLMQFIRRVQDEVHRFAITYHRSLR
DKRTLHSILEDIPNIGEKRRRALLMKFGSVENIKNAKLEELLSTESIDNKAAESIISYFKKHEHNS
>Mature_626_residues
MIIFDFKNQLKILPDEPGVYLMKNSLGEVIYVGKAKILKNRVRQYFQNSKNHSEKVKAMVKNISEFEYIITDSEMEALIL
ECNLIKKYSPRYNILLKDDKFYPFIKVTINEEFPKIFITRKYAKDGNKYFGPYTNIASVYETMNLIKKIFPIRTCKKTIT
EGGNPTRPCLNYHIKKCNAPCAGYISKDEYRNMISEVMELLSGKNKDLVNKLQKDMEDASKSLEFEKAASLRDKIIAINN
IVEKQKVFKSQEGDEDFINLYKDEKDCCVQVFFLRDGKVTGREHFILENSTYQEESSILSQFMISFYGGTPKVPKHIYIP
KEQDTEILEEFLKIKRGSKVNVKVPKKGSKKEMLELVKNNAKLTLEQFKEKLLMDKKINRGCLEELKELLNLDDIPNRIE
SFDISNIQGVDSVGSMIVFENGKAKNSDYRRFSIKNVKNGNEYDSMREILERRFVHGLKEVKEIQERNLQFSNGKFSNFP
DLIMMDGGKGQVNVAKEVLNKLDIQIPVCGLVKDDRHSTRGIIYNNEEIIINRSSNLMQFIRRVQDEVHRFAITYHRSLR
DKRTLHSILEDIPNIGEKRRRALLMKFGSVENIKNAKLEELLSTESIDNKAAESIISYFKKHEHNS

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=632, Percent_Identity=35.4430379746835, Blast_Score=357, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 72770; Mature: 72770

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFDFKNQLKILPDEPGVYLMKNSLGEVIYVGKAKILKNRVRQYFQNSKNHSEKVKAMV
CEEEECCCCCEECCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHH
KNISEFEYIITDSEMEALILECNLIKKYSPRYNILLKDDKFYPFIKVTINEEFPKIFITR
HHHHHHEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEE
KYAKDGNKYFGPYTNIASVYETMNLIKKIFPIRTCKKTITEGGNPTRPCLNYHIKKCNAP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
CAGYISKDEYRNMISEVMELLSGKNKDLVNKLQKDMEDASKSLEFEKAASLRDKIIAINN
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IVEKQKVFKSQEGDEDFINLYKDEKDCCVQVFFLRDGKVTGREHFILENSTYQEESSILS
HHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHH
QFMISFYGGTPKVPKHIYIPKEQDTEILEEFLKIKRGSKVNVKVPKKGSKKEMLELVKNN
HHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCC
AKLTLEQFKEKLLMDKKINRGCLEELKELLNLDDIPNRIESFDISNIQGVDSVGSMIVFE
CCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHCCEEEEE
NGKAKNSDYRRFSIKNVKNGNEYDSMREILERRFVHGLKEVKEIQERNLQFSNGKFSNFP
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
DLIMMDGGKGQVNVAKEVLNKLDIQIPVCGLVKDDRHSTRGIIYNNEEIIINRSSNLMQF
CEEEECCCCCCHHHHHHHHHHCCCCEEEECCEECCCCCCCCEEECCCEEEEECCHHHHHH
IRRVQDEVHRFAITYHRSLRDKRTLHSILEDIPNIGEKRRRALLMKFGSVENIKNAKLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHH
LLSTESIDNKAAESIISYFKKHEHNS
HHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIFDFKNQLKILPDEPGVYLMKNSLGEVIYVGKAKILKNRVRQYFQNSKNHSEKVKAMV
CEEEECCCCCEECCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHH
KNISEFEYIITDSEMEALILECNLIKKYSPRYNILLKDDKFYPFIKVTINEEFPKIFITR
HHHHHHEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEE
KYAKDGNKYFGPYTNIASVYETMNLIKKIFPIRTCKKTITEGGNPTRPCLNYHIKKCNAP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
CAGYISKDEYRNMISEVMELLSGKNKDLVNKLQKDMEDASKSLEFEKAASLRDKIIAINN
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IVEKQKVFKSQEGDEDFINLYKDEKDCCVQVFFLRDGKVTGREHFILENSTYQEESSILS
HHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHH
QFMISFYGGTPKVPKHIYIPKEQDTEILEEFLKIKRGSKVNVKVPKKGSKKEMLELVKNN
HHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCC
AKLTLEQFKEKLLMDKKINRGCLEELKELLNLDDIPNRIESFDISNIQGVDSVGSMIVFE
CCEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHCCEEEEE
NGKAKNSDYRRFSIKNVKNGNEYDSMREILERRFVHGLKEVKEIQERNLQFSNGKFSNFP
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
DLIMMDGGKGQVNVAKEVLNKLDIQIPVCGLVKDDRHSTRGIIYNNEEIIINRSSNLMQF
CEEEECCCCCCHHHHHHHHHHCCCCEEEECCEECCCCCCCCEEECCCEEEEECCHHHHHH
IRRVQDEVHRFAITYHRSLRDKRTLHSILEDIPNIGEKRRRALLMKFGSVENIKNAKLEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHH
LLSTESIDNKAAESIISYFKKHEHNS
HHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA