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The map label for this gene is bceR [H]

Identifier: 187935627

GI number: 187935627

Start: 1156468

End: 1157136

Strand: Reverse

Name: bceR [H]

Synonym: CLL_A1126

Alternate gene names: 187935627

Gene position: 1157136-1156468 (Counterclockwise)

Preceding gene: 187932461

Following gene: 187934429

Centisome position: 30.45

GC content: 26.46

Gene sequence:

>669_bases
ATGTTTAAAATAATGATAATCGAAGATAATAAAACAATTAGAGAAAAACTTGCTGATTTGCTCGTTAAATATGGATATGA
GGTATTTTTACCTAAAGATTTTACAACTATAATTGAAGATTTTAATAAAAGTAATCCACACCTTATTCTTCTTGACATAA
ATCTTCCTATATTTGATGGCTTTCACTTTTGCAAAGAAATAAGAAAATATTCTAATATTCCTATTATATTTGTTACAAGT
CGTGATAGTAATATGGATGAAATAATGAGTATGACCGTAGGTGGGGATGATTTTATAACTAAACCTTATGACTCACAAAT
ATTAATTGCACGAATAACTGCTGTACTTAGAAGAAGCTATAATAATCTATCAAATGATATTCTTGAATATAAAGGAGTTA
GCTTAAATTTAGGAAAAGGAAATGTAACCTACCAAAACAAAACTATTGATCTTACTAAAAATGAATTTAAAATACTTAAT
AATTTGCTTCAAAATAAAGGAAGTATTGTTACAAGAGATGATTTAATGAACTATTTATGGAATGATGATGTGTTCTTGGA
TGATAACACTTTAACTGTTAACATAAACAGACTTAGAAAAAAATTAGAAGAGATTAACATTCATGACTTTATTGAAACTA
GGCGTGGATTGGGGTACATAATATCATGA

Upstream 100 bases:

>100_bases
TTCATGTTATACTTTTTTTAATTAAGCTTTATATAATTAAATATTAAAGCTTTTAAATGTAAATACTAAGTTAATAATAA
TTAAGAAATAAGGTGGTAAT

Downstream 100 bases:

>100_bases
GTTTAAAAGAATATATTAATGGAAATAAAACTTTAATACTTTTAAATCTCTTTTATATTATTCTATTAATTGTATTTTTA
AGGTTATTTAGCATCCCACA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MFKIMIIEDNKTIREKLADLLVKYGYEVFLPKDFTTIIEDFNKSNPHLILLDINLPIFDGFHFCKEIRKYSNIPIIFVTS
RDSNMDEIMSMTVGGDDFITKPYDSQILIARITAVLRRSYNNLSNDILEYKGVSLNLGKGNVTYQNKTIDLTKNEFKILN
NLLQNKGSIVTRDDLMNYLWNDDVFLDDNTLTVNINRLRKKLEEINIHDFIETRRGLGYIIS

Sequences:

>Translated_222_residues
MFKIMIIEDNKTIREKLADLLVKYGYEVFLPKDFTTIIEDFNKSNPHLILLDINLPIFDGFHFCKEIRKYSNIPIIFVTS
RDSNMDEIMSMTVGGDDFITKPYDSQILIARITAVLRRSYNNLSNDILEYKGVSLNLGKGNVTYQNKTIDLTKNEFKILN
NLLQNKGSIVTRDDLMNYLWNDDVFLDDNTLTVNINRLRKKLEEINIHDFIETRRGLGYIIS
>Mature_222_residues
MFKIMIIEDNKTIREKLADLLVKYGYEVFLPKDFTTIIEDFNKSNPHLILLDINLPIFDGFHFCKEIRKYSNIPIIFVTS
RDSNMDEIMSMTVGGDDFITKPYDSQILIARITAVLRRSYNNLSNDILEYKGVSLNLGKGNVTYQNKTIDLTKNEFKILN
NLLQNKGSIVTRDDLMNYLWNDDVFLDDNTLTVNINRLRKKLEEINIHDFIETRRGLGYIIS

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.2869955156951, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=32.7272727272727, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.5991189427313, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=30.1801801801802, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=27.8538812785388, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.1818181818182, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=32.5688073394495, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.4841628959276, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=30.1310043668122, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.646017699115, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=28, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=28.8288288288288, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=27.1493212669683, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=30.5084745762712, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25886; Mature: 25886

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKIMIIEDNKTIREKLADLLVKYGYEVFLPKDFTTIIEDFNKSNPHLILLDINLPIFDG
CEEEEEEECCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCEEEEEEECCCHHHH
FHFCKEIRKYSNIPIIFVTSRDSNMDEIMSMTVGGDDFITKPYDSQILIARITAVLRRSY
HHHHHHHHHHCCCCEEEEECCCCCHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
NNLSNDILEYKGVSLNLGKGNVTYQNKTIDLTKNEFKILNNLLQNKGSIVTRDDLMNYLW
HHHHHHHHHHCCCEEECCCCCEEEECCEEEECHHHHHHHHHHHHCCCCEEEHHHHHHHHC
NDDVFLDDNTLTVNINRLRKKLEEINIHDFIETRRGLGYIIS
CCCEEEECCEEEEEHHHHHHHHHHCCHHHHHHHHCCCCEECC
>Mature Secondary Structure
MFKIMIIEDNKTIREKLADLLVKYGYEVFLPKDFTTIIEDFNKSNPHLILLDINLPIFDG
CEEEEEEECCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCEEEEEEECCCHHHH
FHFCKEIRKYSNIPIIFVTSRDSNMDEIMSMTVGGDDFITKPYDSQILIARITAVLRRSY
HHHHHHHHHHCCCCEEEEECCCCCHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
NNLSNDILEYKGVSLNLGKGNVTYQNKTIDLTKNEFKILNNLLQNKGSIVTRDDLMNYLW
HHHHHHHHHHCCCEEECCCCCEEEECCEEEECHHHHHHHHHHHHCCCCEEEHHHHHHHHC
NDDVFLDDNTLTVNINRLRKKLEEINIHDFIETRRGLGYIIS
CCCEEEECCEEEEEHHHHHHHHHHCCHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]