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The map label for this gene is iolR [H]

Identifier: 187934785

GI number: 187934785

Start: 1333009

End: 1333770

Strand: Reverse

Name: iolR [H]

Synonym: CLL_A1299

Alternate gene names: 187934785

Gene position: 1333770-1333009 (Counterclockwise)

Preceding gene: 187933556

Following gene: 187934700

Centisome position: 35.1

GC content: 26.64

Gene sequence:

>762_bases
ATGCGTTTAAAAAGGCTTGATTTATTAGAAGAATTTATTTATAAACATAGAACCGTATCAATAGATAAACTTTGCGAAGA
ATTTAAAATGTCAAAAAATACAATTCGTAGAGATATAGATGCCTTAGTTGATAAAGGCGTAATAAAAAAAGTATATGGGG
GCGTTACAGTAAATACTCAAAGTAATGAGCTGCTTCCATTTGAAGAAAGAACAATAAAAAATAACAGTGCTAAAATAGAT
ATTGCTAAAAAAGCTGCTGAATTTATTGAAGATGGGGACTCTATATTCATAGATTCCGGTACTACCACATTAAATATAAT
TGATTATTTAAATGATAAAAACAATATAACATTATTCACCAATAGCATTAATGTTATTTTAAAAGCGATTCCTCATGATA
ATATTGATATAATATGTTTATCTGGTAGGTTTAATAGAACTACTTTTTCTTTTACAGGGCTAACTTCTAGTGATGTCTTA
TCAACTTATAATATAAATAAATCTTTTATGGCCTGTACTGGAATTTCATTAGAAAATGGCCTTACTCACACTTCACCTAA
TGAATTTAAAATAAAGAAAGTAGCTGTTTCTAAAAGCCATAAAACATTTTTACTTGCAGATAGTTCAAAATTTAATATAG
TCTCTTTAATGACCTTTTGTGATGTAAAAGATCTAGATTATCTAATTACAGATAAGTGTCCTTCTGCCAAATATATTGAG
TATTTTAATAATTATAATGTTGAACTTATAGTTCCTAATTAA

Upstream 100 bases:

>100_bases
TGGTATAATGATGATAATGTCTTTTACTTTATAATTTCATAGTTTATAATTAATATTAGATTCCATATTTTTGAAATAAA
ATAAAAAAGGGGGTATTTAG

Downstream 100 bases:

>100_bases
ATTAAAAGGTATTATTAGATAGGGTTAATACAAAAGTGATATATGATAATTAATAGTTGTGGTTGAAATTCTTAATAACT
TTCTATAAAAATATATCTTT

Product: DNA-binding protein IolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRLKRLDLLEEFIYKHRTVSIDKLCEEFKMSKNTIRRDIDALVDKGVIKKVYGGVTVNTQSNELLPFEERTIKNNSAKID
IAKKAAEFIEDGDSIFIDSGTTTLNIIDYLNDKNNITLFTNSINVILKAIPHDNIDIICLSGRFNRTTFSFTGLTSSDVL
STYNINKSFMACTGISLENGLTHTSPNEFKIKKVAVSKSHKTFLLADSSKFNIVSLMTFCDVKDLDYLITDKCPSAKYIE
YFNNYNVELIVPN

Sequences:

>Translated_253_residues
MRLKRLDLLEEFIYKHRTVSIDKLCEEFKMSKNTIRRDIDALVDKGVIKKVYGGVTVNTQSNELLPFEERTIKNNSAKID
IAKKAAEFIEDGDSIFIDSGTTTLNIIDYLNDKNNITLFTNSINVILKAIPHDNIDIICLSGRFNRTTFSFTGLTSSDVL
STYNINKSFMACTGISLENGLTHTSPNEFKIKKVAVSKSHKTFLLADSSKFNIVSLMTFCDVKDLDYLITDKCPSAKYIE
YFNNYNVELIVPN
>Mature_253_residues
MRLKRLDLLEEFIYKHRTVSIDKLCEEFKMSKNTIRRDIDALVDKGVIKKVYGGVTVNTQSNELLPFEERTIKNNSAKID
IAKKAAEFIEDGDSIFIDSGTTTLNIIDYLNDKNNITLFTNSINVILKAIPHDNIDIICLSGRFNRTTFSFTGLTSSDVL
STYNINKSFMACTGISLENGLTHTSPNEFKIKKVAVSKSHKTFLLADSSKFNIVSLMTFCDVKDLDYLITDKCPSAKYIE
YFNNYNVELIVPN

Specific function: Iol operon repressor [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788069, Length=247, Percent_Identity=28.3400809716599, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=30.5220883534137, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789519, Length=250, Percent_Identity=25.6, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=25.2032520325203, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=24.8031496062992, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790753, Length=258, Percent_Identity=25.1937984496124, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI226510968, Length=229, Percent_Identity=26.2008733624454, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=25.6410256410256, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787063, Length=223, Percent_Identity=27.3542600896861, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790635, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=25.2173913043478, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28657; Mature: 28657

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKRLDLLEEFIYKHRTVSIDKLCEEFKMSKNTIRRDIDALVDKGVIKKVYGGVTVNTQ
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEECC
SNELLPFEERTIKNNSAKIDIAKKAAEFIEDGDSIFIDSGTTTLNIIDYLNDKNNITLFT
CCCCCCCHHHHCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCEEEEEEEECCCCCEEEEE
NSINVILKAIPHDNIDIICLSGRFNRTTFSFTGLTSSDVLSTYNINKSFMACTGISLENG
CCEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCHHEEEECCCCCEEEEECCCCCCC
LTHTSPNEFKIKKVAVSKSHKTFLLADSSKFNIVSLMTFCDVKDLDYLITDKCPSAKYIE
CCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEECCCCCCHHHH
YFNNYNVELIVPN
HHCCCCEEEEECC
>Mature Secondary Structure
MRLKRLDLLEEFIYKHRTVSIDKLCEEFKMSKNTIRRDIDALVDKGVIKKVYGGVTVNTQ
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEECC
SNELLPFEERTIKNNSAKIDIAKKAAEFIEDGDSIFIDSGTTTLNIIDYLNDKNNITLFT
CCCCCCCHHHHCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCEEEEEEEECCCCCEEEEE
NSINVILKAIPHDNIDIICLSGRFNRTTFSFTGLTSSDVLSTYNINKSFMACTGISLENG
CCEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCHHEEEECCCCCEEEEECCCCCCC
LTHTSPNEFKIKKVAVSKSHKTFLLADSSKFNIVSLMTFCDVKDLDYLITDKCPSAKYIE
CCCCCCCCEEEEEEEECCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEECCCCCCHHHH
YFNNYNVELIVPN
HHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]