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The map label for this gene is lytA [H]

Identifier: 187934696

GI number: 187934696

Start: 3377745

End: 3379424

Strand: Reverse

Name: lytA [H]

Synonym: CLL_A3231

Alternate gene names: 187934696

Gene position: 3379424-3377745 (Counterclockwise)

Preceding gene: 187933479

Following gene: 187935530

Centisome position: 88.92

GC content: 27.38

Gene sequence:

>1680_bases
ATGAATAAAAGATTAAAAAGAATTATTGCAATAGCACTTACAATTAGTGCATTTTCAACAATACAACCAACAAAATATAT
GAATTTATTTGCTACAACAGCATATGCTGCAAGCAGTCATATAAGTAATTTAATATTAAACAAAACAGATACATCAAATG
AACTTAAGTTATATAGAGATGATGAGTATGATGTAAGTACAGAATTTAGAACTAGCAGAAGTGAGTATTATGCGAAGACT
TCATTAAGAAGTGTTAATATAAGCTGTGATACAGATTCTAATTATGAAACTTATATTTTTGCAGATAGCAATAAAAGATC
AACTGCTTTTGAATCAGATGAAGAAGTAGAACTTGGAAAAGGAACTACAACTTTATATGTAAGAACTTATAAAGAAGGAC
GTTTTGATAAGAACAATGTTAAAAATGATGTTGTAAATGAGTACGAAATTCATATAGAAAGAACTTCATCAGGTTCTTCA
AATAATAGTAGTTTATATTTATCTAGTATTTCTTTAGACTATGGTAAAATATCTTTTTCCAAGACTAAGACAAGCTATGA
TGTAGATGTAAATTCATCTGTTGATGAAATAGAAATTAAAGCTAAACCATCAGATAAAGATTATACTGTAAGAATAGATG
GTACAAAAGTAAAAGATAGTAATGGATATGAGGGAACTGTAGATCTTAAAAAAGGTAAAAATGTCATTGAAGTTTCAGTA
ACTGATGAAGATGATAATGAAAAAATATATACATTAAATGTATATAGAGGTGGAAGAGATTCTTCAAGTTCAGATTCAAG
TAATTCAGGAAAAGAAGATAATAAACAAGATCCAGTATATTTAGATGATTTAAAATTAAATAATGGAGATATTAAATTAG
ATTTTAATAAGAAAGTTACATCATATGATGTAAAAGTAGCATCTAATATAGATTCAGTGACAATAGAAGCTGAACCAGAT
GATGATGAATATGACGTAACAGTAGATAAGAAAAAAGTAAATTCTAAAAATCAAAGAACTGTTGATTTAACTTTAAATAA
AAAAAATGTAATAGAAGTTAAGGTTACAAATGAAGATGATGAATACAGAACATATACTTTAAATATAACAAGAGGAACAG
TTTCTTCATCAAATGATAATAATAGCAATAATAATCCAGGTACAGTAACACCTGGTGGAACTGTAACTCCAGGCGGTGGA
AATAATAATAATTCTTCATCAAATAATAATGCAAGTACTATTAAAGGTAAATGGGTTAAAACATCAAATGGAAATTGGCA
ATATTATGATGCTAATGGAATTGCTTTAAAGAATCAATGGTTCAAAGATACTAATGGAAAATGGTATTATTTAACTGAAG
ATGGAAATATGAAAACAAACTGGTTAAAGAACAATGATAAATGGTATTACTTAAATTATGATGGTTCAATGATGACTGGT
TGGATTAAAATAAATGGGTTCTGGAATTATTTTAATACTGATGGAGCAATGTTAGTTGGTTGGTATAAAATAGGAGATAA
TTGGTACTACTCAAATGCTGATGGAGCTATGAGAACAGGTTGGTTACAAGAAGGAAAGACAAAATACTATTTAAATGATG
ATGGAACAATGCAAAAAGGACAAAAAACAATAAGTGGAGTTAATTATAACTTTGATGCTAGTGGTAAATTAGTAGAATAG

Upstream 100 bases:

>100_bases
CGCATTATTAAAAACATAATAAAAAATTAAGGGGATATGTAATGCATTTTATAGCTTAAAATGGTAAAATAATAGTATAT
ATGCAATGGGAGGAAGAATT

Downstream 100 bases:

>100_bases
TATATAGTTTAAGTCACCCTTAAGGTGAAAAAAATGGAAAAAGTCATGTTTGTTCATGGCTTTTTTTGTGAAAAAAATTA
ATTATCAAGGAATAATTGGA

Product: choline binding protein A

Products: NA

Alternate protein names: Cell wall hydrolase; Mucopeptide aminohydrolase; Murein hydrolase; N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MNKRLKRIIAIALTISAFSTIQPTKYMNLFATTAYAASSHISNLILNKTDTSNELKLYRDDEYDVSTEFRTSRSEYYAKT
SLRSVNISCDTDSNYETYIFADSNKRSTAFESDEEVELGKGTTTLYVRTYKEGRFDKNNVKNDVVNEYEIHIERTSSGSS
NNSSLYLSSISLDYGKISFSKTKTSYDVDVNSSVDEIEIKAKPSDKDYTVRIDGTKVKDSNGYEGTVDLKKGKNVIEVSV
TDEDDNEKIYTLNVYRGGRDSSSSDSSNSGKEDNKQDPVYLDDLKLNNGDIKLDFNKKVTSYDVKVASNIDSVTIEAEPD
DDEYDVTVDKKKVNSKNQRTVDLTLNKKNVIEVKVTNEDDEYRTYTLNITRGTVSSSNDNNSNNNPGTVTPGGTVTPGGG
NNNNSSSNNNASTIKGKWVKTSNGNWQYYDANGIALKNQWFKDTNGKWYYLTEDGNMKTNWLKNNDKWYYLNYDGSMMTG
WIKINGFWNYFNTDGAMLVGWYKIGDNWYYSNADGAMRTGWLQEGKTKYYLNDDGTMQKGQKTISGVNYNFDASGKLVE

Sequences:

>Translated_559_residues
MNKRLKRIIAIALTISAFSTIQPTKYMNLFATTAYAASSHISNLILNKTDTSNELKLYRDDEYDVSTEFRTSRSEYYAKT
SLRSVNISCDTDSNYETYIFADSNKRSTAFESDEEVELGKGTTTLYVRTYKEGRFDKNNVKNDVVNEYEIHIERTSSGSS
NNSSLYLSSISLDYGKISFSKTKTSYDVDVNSSVDEIEIKAKPSDKDYTVRIDGTKVKDSNGYEGTVDLKKGKNVIEVSV
TDEDDNEKIYTLNVYRGGRDSSSSDSSNSGKEDNKQDPVYLDDLKLNNGDIKLDFNKKVTSYDVKVASNIDSVTIEAEPD
DDEYDVTVDKKKVNSKNQRTVDLTLNKKNVIEVKVTNEDDEYRTYTLNITRGTVSSSNDNNSNNNPGTVTPGGTVTPGGG
NNNNSSSNNNASTIKGKWVKTSNGNWQYYDANGIALKNQWFKDTNGKWYYLTEDGNMKTNWLKNNDKWYYLNYDGSMMTG
WIKINGFWNYFNTDGAMLVGWYKIGDNWYYSNADGAMRTGWLQEGKTKYYLNDDGTMQKGQKTISGVNYNFDASGKLVE
>Mature_559_residues
MNKRLKRIIAIALTISAFSTIQPTKYMNLFATTAYAASSHISNLILNKTDTSNELKLYRDDEYDVSTEFRTSRSEYYAKT
SLRSVNISCDTDSNYETYIFADSNKRSTAFESDEEVELGKGTTTLYVRTYKEGRFDKNNVKNDVVNEYEIHIERTSSGSS
NNSSLYLSSISLDYGKISFSKTKTSYDVDVNSSVDEIEIKAKPSDKDYTVRIDGTKVKDSNGYEGTVDLKKGKNVIEVSV
TDEDDNEKIYTLNVYRGGRDSSSSDSSNSGKEDNKQDPVYLDDLKLNNGDIKLDFNKKVTSYDVKVASNIDSVTIEAEPD
DDEYDVTVDKKKVNSKNQRTVDLTLNKKNVIEVKVTNEDDEYRTYTLNITRGTVSSSNDNNSNNNPGTVTPGGTVTPGGG
NNNNSSSNNNASTIKGKWVKTSNGNWQYYDANGIALKNQWFKDTNGKWYYLTEDGNMKTNWLKNNDKWYYLNYDGSMMTG
WIKINGFWNYFNTDGAMLVGWYKIGDNWYYSNADGAMRTGWLQEGKTKYYLNDDGTMQKGQKTISGVNYNFDASGKLVE

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR018337 [H]

Pfam domain/function: PF01510 Amidase_2; PF01473 CW_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 63107; Mature: 63107

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRLKRIIAIALTISAFSTIQPTKYMNLFATTAYAASSHISNLILNKTDTSNELKLYRD
CCHHHHEEEEEEEEEEHHCCCCCCHHEEEEEEHHHHHHHHHHEEEEECCCCCCCEEEEEC
DEYDVSTEFRTSRSEYYAKTSLRSVNISCDTDSNYETYIFADSNKRSTAFESDEEVELGK
CCCCCCCHHCCCCHHEEEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEECC
GTTTLYVRTYKEGRFDKNNVKNDVVNEYEIHIERTSSGSSNNSSLYLSSISLDYGKISFS
CEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCEEEEE
KTKTSYDVDVNSSVDEIEIKAKPSDKDYTVRIDGTKVKDSNGYEGTVDLKKGKNVIEVSV
CCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCEEEECCCCCEEEEECCCCCEEEEEEE
TDEDDNEKIYTLNVYRGGRDSSSSDSSNSGKEDNKQDPVYLDDLKLNNGDIKLDFNKKVT
ECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCEE
SYDVKVASNIDSVTIEAEPDDDEYDVTVDKKKVNSKNQRTVDLTLNKKNVIEVKVTNEDD
EEEEEEECCCCEEEEEECCCCCCEEEEEEHHHCCCCCCEEEEEEECCCEEEEEEECCCCC
EYRTYTLNITRGTVSSSNDNNSNNNPGTVTPGGTVTPGGGNNNNSSSNNNASTIKGKWVK
CEEEEEEEEEECEEECCCCCCCCCCCCEECCCCEECCCCCCCCCCCCCCCCEEEEEEEEE
TSNGNWQYYDANGIALKNQWFKDTNGKWYYLTEDGNMKTNWLKNNDKWYYLNYDGSMMTG
ECCCCEEEEECCCEEEECCCEECCCCEEEEEECCCCEEEEEEECCCEEEEEEECCCEEEE
WIKINGFWNYFNTDGAMLVGWYKIGDNWYYSNADGAMRTGWLQEGKTKYYLNDDGTMQKG
EEEEEEEEEEECCCCEEEEEEEEECCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCC
QKTISGVNYNFDASGKLVE
CHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKRLKRIIAIALTISAFSTIQPTKYMNLFATTAYAASSHISNLILNKTDTSNELKLYRD
CCHHHHEEEEEEEEEEHHCCCCCCHHEEEEEEHHHHHHHHHHEEEEECCCCCCCEEEEEC
DEYDVSTEFRTSRSEYYAKTSLRSVNISCDTDSNYETYIFADSNKRSTAFESDEEVELGK
CCCCCCCHHCCCCHHEEEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEECC
GTTTLYVRTYKEGRFDKNNVKNDVVNEYEIHIERTSSGSSNNSSLYLSSISLDYGKISFS
CEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCEEEEE
KTKTSYDVDVNSSVDEIEIKAKPSDKDYTVRIDGTKVKDSNGYEGTVDLKKGKNVIEVSV
CCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCEEEECCCCCEEEEECCCCCEEEEEEE
TDEDDNEKIYTLNVYRGGRDSSSSDSSNSGKEDNKQDPVYLDDLKLNNGDIKLDFNKKVT
ECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCEE
SYDVKVASNIDSVTIEAEPDDDEYDVTVDKKKVNSKNQRTVDLTLNKKNVIEVKVTNEDD
EEEEEEECCCCEEEEEECCCCCCEEEEEEHHHCCCCCCEEEEEEECCCEEEEEEECCCCC
EYRTYTLNITRGTVSSSNDNNSNNNPGTVTPGGTVTPGGGNNNNSSSNNNASTIKGKWVK
CEEEEEEEEEECEEECCCCCCCCCCCCEECCCCEECCCCCCCCCCCCCCCCEEEEEEEEE
TSNGNWQYYDANGIALKNQWFKDTNGKWYYLTEDGNMKTNWLKNNDKWYYLNYDGSMMTG
ECCCCEEEEECCCEEEECCCEECCCCEEEEEECCCCEEEEEEECCCEEEEEEECCCEEEE
WIKINGFWNYFNTDGAMLVGWYKIGDNWYYSNADGAMRTGWLQEGKTKYYLNDDGTMQKG
EEEEEEEEEEECCCCEEEEEEEEECCEEEEECCCCCEEECCCCCCCEEEEECCCCCCCCC
QKTISGVNYNFDASGKLVE
CHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2875013; 11463916 [H]