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The map label for this gene is mcpB [H]

Identifier: 187934337

GI number: 187934337

Start: 2278398

End: 2280407

Strand: Reverse

Name: mcpB [H]

Synonym: CLL_A2195

Alternate gene names: 187934337

Gene position: 2280407-2278398 (Counterclockwise)

Preceding gene: 187933043

Following gene: 187933362

Centisome position: 60.01

GC content: 26.42

Gene sequence:

>2010_bases
ATGACTATGAGAAAATTAAACTTTAAAAAATTACAAAATCAATTATTGAGTGCTTTTATGTTTCTTATAATTATAGTATG
CATAGGGTTATTCTTTGTATCATCATATATTTCAAAAAAAGCTATAGTTAACACAGTTCAAACCATTTTACCTAATGTTG
CAACACAAGCGTCTTTAGCAATTGAAAATAATATTAATATTAGGCTGAAAACATTAGAAACTTTAGCTGAAAATGAAAAA
TTACAAGATGAAAATGTTGCAATTAAAGAAAAAGTAAATATACTTTTGACAGAAGAAAAAAGAAGTGGACATTTAAAAAT
GAGTATCATTGATATTAATGGAAAATCCAATGATACATTAGGTGAAGAATATGATGTTAAAGATACTGAATATTTTAAGA
ATGGAATTGAAGGAAAATATTCAGTGTCTAATCCTATGACAGTTAATGAAAAATTAGTATTCATTTATAGCGTACCTATT
ATAAAAGATGGAAATACAGTAGGGGTTTTAACTGCAACAAGAGATGAAAATGAATTAAGCAAATATACTAATAATATTAA
AGTTGGAGAAACAGGTCAATCTTTCATCATTAATAATGAAGGTACAGCTATAGCTCATAGGGATAAAAATTTAGTACTAA
AAAAAGATAATAATTTTGAAAATATAAAAAAAGATCCTGAACTTAAAAGTTTAGCAGAAATTGAGAAGAAGATGGTGGCA
GGTGAAAATGGAATAGGAGAATATAACTATGGAAATAAGAAAAAGTATATAGCATATGCTCCAATAAAACCTGTTAATTG
GTCAATTGGTGTTGTTATAGAATCTGGCGAAATATTAAATCATTTAATGATTTTAATAATAAGTGTAGGAATCACAAGCC
TAATAGGTATTTTAATAGCTGTAATTTTTGCAAGAAGGATAGTAAAGTCTATAAATAAGCCAATTATTGCTTCTGTAGAG
AATCTTAAAGTTATTGCGTCAGGTGATTTACAAACGGAAACTACAAATGGATTTTCTAATAGAAGAGATGAATTAGGAAT
AATGGCAAAATCTATAGAATCTATGAAACAGTCTATTATATCAATGTTGAATTCTATAAAAACAAGCTCTAGTGATATAA
AATTACAAACTAATAATGTAGAGGAAATATCCAATGAGCTAAAGTCTTCAAGCAAAAATATTTATTATGCTACAAATGAT
GTTGCAAAAGGAACAGTAAATCAATCAGAAGACTTAATTTATATAACTAATATACTGAAGGGATTTAGTTTAAAATTAGA
TGATATAGTTGATATTATAAAGAATGTAGATTTTAGTATAAGCAATATAAAAAACATGTCTTATAATAGTAATAAGGATA
TGGAAAATGTTATTGAATCAGTGAAAAATGTAAATAATACATTTAATGAACTAATTACTAAAATTAAAGATGTTGAAAAT
AATGTGAATAAAATAAATGAAATAACTAATTTAATAGATGATATATCAGATCAAACTAATCTTTTAGCATTAAATGCAGC
AATAGAAGCAGCAAGAGCAGGGGATTCGGGAAAAGGATTTAAGATAGTTGCAAGCGAAATTAGAAAACTTGCAGAACAAA
GTAAAGTTTCAGCTGTAGATATTTCAAGTTTAATCTCTAAAATATCTAAGGATACTGATTTAATGGTAAATAAAACAAAG
ACTATGAAAAAGGAATTAGACAATCAAGAAAAAGATATAGATACAGCAAAAAAATCATTTGAAACTATTACGGTTTCAGT
TAATGATATAGTGCCTAAAATGGTTGTTACTAATAATTCTGTTCAAAATTTAAATGCAAGCAAAGACGATATAATGAACA
AAATAGAAAGTGCATCTTCAGTAGCACAAGAAGTGTCAGCTGCAGCTGAGGAAATAGCAGCATCAACTGAAGAAATGAAT
AAGTATGCAGAAAGCTTGGCTAAATTAGTAAATGCATTAAATGATATGAGCGAAGATATGATGAAGAATGTTAACAAATT
CAAAATTTAA

Upstream 100 bases:

>100_bases
TGGTATTTATTAGAATAGTACACATTAAAAAAATATATTCATAATATACTTTTAAGGGGAACCATAACAAAACAAAAAAT
AATTTAAGATATGAGAAGAG

Downstream 100 bases:

>100_bases
GACTATGTTTTTAGAAGAGTGTTGATATACATGCTATTTTGACTAGTGAATATATCAATACAGATTTAAAACATAGCTAA
ATTTAAATATTCAAAGACTA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MTMRKLNFKKLQNQLLSAFMFLIIIVCIGLFFVSSYISKKAIVNTVQTILPNVATQASLAIENNINIRLKTLETLAENEK
LQDENVAIKEKVNILLTEEKRSGHLKMSIIDINGKSNDTLGEEYDVKDTEYFKNGIEGKYSVSNPMTVNEKLVFIYSVPI
IKDGNTVGVLTATRDENELSKYTNNIKVGETGQSFIINNEGTAIAHRDKNLVLKKDNNFENIKKDPELKSLAEIEKKMVA
GENGIGEYNYGNKKKYIAYAPIKPVNWSIGVVIESGEILNHLMILIISVGITSLIGILIAVIFARRIVKSINKPIIASVE
NLKVIASGDLQTETTNGFSNRRDELGIMAKSIESMKQSIISMLNSIKTSSSDIKLQTNNVEEISNELKSSSKNIYYATND
VAKGTVNQSEDLIYITNILKGFSLKLDDIVDIIKNVDFSISNIKNMSYNSNKDMENVIESVKNVNNTFNELITKIKDVEN
NVNKINEITNLIDDISDQTNLLALNAAIEAARAGDSGKGFKIVASEIRKLAEQSKVSAVDISSLISKISKDTDLMVNKTK
TMKKELDNQEKDIDTAKKSFETITVSVNDIVPKMVVTNNSVQNLNASKDDIMNKIESASSVAQEVSAAAEEIAASTEEMN
KYAESLAKLVNALNDMSEDMMKNVNKFKI

Sequences:

>Translated_669_residues
MTMRKLNFKKLQNQLLSAFMFLIIIVCIGLFFVSSYISKKAIVNTVQTILPNVATQASLAIENNINIRLKTLETLAENEK
LQDENVAIKEKVNILLTEEKRSGHLKMSIIDINGKSNDTLGEEYDVKDTEYFKNGIEGKYSVSNPMTVNEKLVFIYSVPI
IKDGNTVGVLTATRDENELSKYTNNIKVGETGQSFIINNEGTAIAHRDKNLVLKKDNNFENIKKDPELKSLAEIEKKMVA
GENGIGEYNYGNKKKYIAYAPIKPVNWSIGVVIESGEILNHLMILIISVGITSLIGILIAVIFARRIVKSINKPIIASVE
NLKVIASGDLQTETTNGFSNRRDELGIMAKSIESMKQSIISMLNSIKTSSSDIKLQTNNVEEISNELKSSSKNIYYATND
VAKGTVNQSEDLIYITNILKGFSLKLDDIVDIIKNVDFSISNIKNMSYNSNKDMENVIESVKNVNNTFNELITKIKDVEN
NVNKINEITNLIDDISDQTNLLALNAAIEAARAGDSGKGFKIVASEIRKLAEQSKVSAVDISSLISKISKDTDLMVNKTK
TMKKELDNQEKDIDTAKKSFETITVSVNDIVPKMVVTNNSVQNLNASKDDIMNKIESASSVAQEVSAAAEEIAASTEEMN
KYAESLAKLVNALNDMSEDMMKNVNKFKI
>Mature_668_residues
TMRKLNFKKLQNQLLSAFMFLIIIVCIGLFFVSSYISKKAIVNTVQTILPNVATQASLAIENNINIRLKTLETLAENEKL
QDENVAIKEKVNILLTEEKRSGHLKMSIIDINGKSNDTLGEEYDVKDTEYFKNGIEGKYSVSNPMTVNEKLVFIYSVPII
KDGNTVGVLTATRDENELSKYTNNIKVGETGQSFIINNEGTAIAHRDKNLVLKKDNNFENIKKDPELKSLAEIEKKMVAG
ENGIGEYNYGNKKKYIAYAPIKPVNWSIGVVIESGEILNHLMILIISVGITSLIGILIAVIFARRIVKSINKPIIASVEN
LKVIASGDLQTETTNGFSNRRDELGIMAKSIESMKQSIISMLNSIKTSSSDIKLQTNNVEEISNELKSSSKNIYYATNDV
AKGTVNQSEDLIYITNILKGFSLKLDDIVDIIKNVDFSISNIKNMSYNSNKDMENVIESVKNVNNTFNELITKIKDVENN
VNKINEITNLIDDISDQTNLLALNAAIEAARAGDSGKGFKIVASEIRKLAEQSKVSAVDISSLISKISKDTDLMVNKTKT
MKKELDNQEKDIDTAKKSFETITVSVNDIVPKMVVTNNSVQNLNASKDDIMNKIESASSVAQEVSAAAEEIAASTEEMNK
YAESLAKLVNALNDMSEDMMKNVNKFKI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=375, Percent_Identity=25.6, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI2367378, Length=350, Percent_Identity=26, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1789453, Length=300, Percent_Identity=26.3333333333333, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788195, Length=338, Percent_Identity=25.4437869822485, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788194, Length=296, Percent_Identity=25.3378378378378, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 74143; Mature: 74012

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRKLNFKKLQNQLLSAFMFLIIIVCIGLFFVSSYISKKAIVNTVQTILPNVATQASLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEE
IENNINIRLKTLETLAENEKLQDENVAIKEKVNILLTEEKRSGHLKMSIIDINGKSNDTL
EECCCCEEEEHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCC
GEEYDVKDTEYFKNGIEGKYSVSNPMTVNEKLVFIYSVPIIKDGNTVGVLTATRDENELS
CCCCCCCCHHHHHCCCCCCEECCCCCEECCEEEEEEEEEEEECCCEEEEEEECCCHHHHH
KYTNNIKVGETGQSFIINNEGTAIAHRDKNLVLKKDNNFENIKKDPELKSLAEIEKKMVA
HHHCCCEECCCCCEEEEECCCCEEEECCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHC
GENGIGEYNYGNKKKYIAYAPIKPVNWSIGVVIESGEILNHLMILIISVGITSLIGILIA
CCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VIFARRIVKSINKPIIASVENLKVIASGDLQTETTNGFSNRRDELGIMAKSIESMKQSII
HHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SMLNSIKTSSSDIKLQTNNVEEISNELKSSSKNIYYATNDVAKGTVNQSEDLIYITNILK
HHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHC
GFSLKLDDIVDIIKNVDFSISNIKNMSYNSNKDMENVIESVKNVNNTFNELITKIKDVEN
CCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVNKINEITNLIDDISDQTNLLALNAAIEAARAGDSGKGFKIVASEIRKLAEQSKVSAVD
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
ISSLISKISKDTDLMVNKTKTMKKELDNQEKDIDTAKKSFETITVSVNDIVPKMVVTNNS
HHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCEEEEEEHHHHCCCCEEECCC
VQNLNASKDDIMNKIESASSVAQEVSAAAEEIAASTEEMNKYAESLAKLVNALNDMSEDM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKNVNKFKI
HHHHHHCCC
>Mature Secondary Structure 
TMRKLNFKKLQNQLLSAFMFLIIIVCIGLFFVSSYISKKAIVNTVQTILPNVATQASLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEE
IENNINIRLKTLETLAENEKLQDENVAIKEKVNILLTEEKRSGHLKMSIIDINGKSNDTL
EECCCCEEEEHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCC
GEEYDVKDTEYFKNGIEGKYSVSNPMTVNEKLVFIYSVPIIKDGNTVGVLTATRDENELS
CCCCCCCCHHHHHCCCCCCEECCCCCEECCEEEEEEEEEEEECCCEEEEEEECCCHHHHH
KYTNNIKVGETGQSFIINNEGTAIAHRDKNLVLKKDNNFENIKKDPELKSLAEIEKKMVA
HHHCCCEECCCCCEEEEECCCCEEEECCCCEEEECCCCHHCCCCCCCHHHHHHHHHHHHC
GENGIGEYNYGNKKKYIAYAPIKPVNWSIGVVIESGEILNHLMILIISVGITSLIGILIA
CCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VIFARRIVKSINKPIIASVENLKVIASGDLQTETTNGFSNRRDELGIMAKSIESMKQSII
HHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SMLNSIKTSSSDIKLQTNNVEEISNELKSSSKNIYYATNDVAKGTVNQSEDLIYITNILK
HHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHC
GFSLKLDDIVDIIKNVDFSISNIKNMSYNSNKDMENVIESVKNVNNTFNELITKIKDVEN
CCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVNKINEITNLIDDISDQTNLLALNAAIEAARAGDSGKGFKIVASEIRKLAEQSKVSAVD
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
ISSLISKISKDTDLMVNKTKTMKKELDNQEKDIDTAKKSFETITVSVNDIVPKMVVTNNS
HHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCEEEEEEHHHHCCCCEEECCC
VQNLNASKDDIMNKIESASSVAQEVSAAAEEIAASTEEMNKYAESLAKLVNALNDMSEDM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKNVNKFKI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]