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The map label for this gene is apeB [H]

Identifier: 187933671

GI number: 187933671

Start: 3430479

End: 3431768

Strand: Reverse

Name: apeB [H]

Synonym: CLL_A3269

Alternate gene names: 187933671

Gene position: 3431768-3430479 (Counterclockwise)

Preceding gene: 187934417

Following gene: 187932596

Centisome position: 90.3

GC content: 30.54

Gene sequence:

>1290_bases
ATGAACACAGCAAAAGATTTATTAAATTTTATAAATAATAGTAAAAGTGCATTTCATAGTGCTCATGAAGTTAAATCAAT
TTTAGATAAAGAGGGATTTGTAGAAATTAAAGAATGTGATAAATGGGATTTAAAACATGGTGGAAAATACTATGTTATGA
AAAATGAATCTGCAATAATAGGATTTGAAATTGGAAGTGGAGATATAGCAGAAGAAGGATTTAGATTAATAGGAGCTCAT
ACAGACTCTCCAGGATTCAGAATAAAACCACATGCAGAAATGACAGTAGAAGATCATTACGTTAAATTAAACACAGAAGT
TTATGGTGGAGCAATACTTAGTACATGGTTTGATAGACCGTTATCAATTGCTGGTAGAGTTACATTAAAAGGAAGTAATC
CATTAAAACCACAAGTTAAACTAGTAGATTTAAATAAGCCTGTTTTAATAATACCAAGCTTAGCGATACACATGAATAGA
ACTATTAATGAAGGCTATGAATATAACAAACAAAAAGATACATTACCATTACTTACAATGGCAACTGATAAGTTAGAAAA
AGATGGTTACTTACTTAAGTTAATTGCGGAAAGCTTAAATGTTAAAGAAAAAGAAATAGTAGATTTTGATTTATTCGTAT
ATGAATATGAAAAGGGATGCTTATTTGGAATGAATGAAGAATTCATTTCAGCAGGAAGATTAGATGATCTTTGGATGGTA
TATGCAGGACTTGTAGCATTACTTCAAAGTAAATCTAACAAAGCAACAAAAGTTTTAGTTGCACTTGATAATGAAGAAAT
AGGAAGTTTAACATCTCAAGGTGCAAATTCTTCATTACTTGAAAACATATTAGAAAGAATAACATTAGCACTTGGAAAAG
ACAGAGAAGATTTCAAGAGATCATTATCAAACTCAGTTATGATTTCAGCAGATTTAGCTCATGCTCTTCATCCAAATTAT
ATAGAAAAACATGATCCAACAAACAGGCCACTTGTTGGAAAAGGACCTGTTATAAAAATAGCTGCATCAGGAAGTTATTC
AACAGATAGCTACGCAGCAGCAATATTTAAACAAGTTTGTAAAAATGCTGATGTACCATGCCAAGAATTTGTAAATAGAT
CAGATGTTAAGGGTGGAACAACAATAGGACCAATAACTGCATCTAAATTAAATATTCCAGTTATAGACATGGGAGCACCA
TTACTTTCAATGCATTCAGTAAGAGAACTTGCAAGCGTTAAAGATAATGAATATACAATAAAAGCATTTACTGAATTTCT
TTCACTATAG

Upstream 100 bases:

>100_bases
TAAATCTGTATATTTCAAGTAATACATTTTTATACTTATATTTGTATATAATAATTTTTAGTAATAGTTTTAAGACTATT
ATATCGAGAGGGGAATTTTT

Downstream 100 bases:

>100_bases
TATAGATAAATTGAGAATTTAAAAATAAAGTTATAATTTTTAGAAGCTGTTTATTATAAGAATATTCATAATAAGCAGCT
TCTTTTTTGTATACAAATAA

Product: aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MNTAKDLLNFINNSKSAFHSAHEVKSILDKEGFVEIKECDKWDLKHGGKYYVMKNESAIIGFEIGSGDIAEEGFRLIGAH
TDSPGFRIKPHAEMTVEDHYVKLNTEVYGGAILSTWFDRPLSIAGRVTLKGSNPLKPQVKLVDLNKPVLIIPSLAIHMNR
TINEGYEYNKQKDTLPLLTMATDKLEKDGYLLKLIAESLNVKEKEIVDFDLFVYEYEKGCLFGMNEEFISAGRLDDLWMV
YAGLVALLQSKSNKATKVLVALDNEEIGSLTSQGANSSLLENILERITLALGKDREDFKRSLSNSVMISADLAHALHPNY
IEKHDPTNRPLVGKGPVIKIAASGSYSTDSYAAAIFKQVCKNADVPCQEFVNRSDVKGGTTIGPITASKLNIPVIDMGAP
LLSMHSVRELASVKDNEYTIKAFTEFLSL

Sequences:

>Translated_429_residues
MNTAKDLLNFINNSKSAFHSAHEVKSILDKEGFVEIKECDKWDLKHGGKYYVMKNESAIIGFEIGSGDIAEEGFRLIGAH
TDSPGFRIKPHAEMTVEDHYVKLNTEVYGGAILSTWFDRPLSIAGRVTLKGSNPLKPQVKLVDLNKPVLIIPSLAIHMNR
TINEGYEYNKQKDTLPLLTMATDKLEKDGYLLKLIAESLNVKEKEIVDFDLFVYEYEKGCLFGMNEEFISAGRLDDLWMV
YAGLVALLQSKSNKATKVLVALDNEEIGSLTSQGANSSLLENILERITLALGKDREDFKRSLSNSVMISADLAHALHPNY
IEKHDPTNRPLVGKGPVIKIAASGSYSTDSYAAAIFKQVCKNADVPCQEFVNRSDVKGGTTIGPITASKLNIPVIDMGAP
LLSMHSVRELASVKDNEYTIKAFTEFLSL
>Mature_429_residues
MNTAKDLLNFINNSKSAFHSAHEVKSILDKEGFVEIKECDKWDLKHGGKYYVMKNESAIIGFEIGSGDIAEEGFRLIGAH
TDSPGFRIKPHAEMTVEDHYVKLNTEVYGGAILSTWFDRPLSIAGRVTLKGSNPLKPQVKLVDLNKPVLIIPSLAIHMNR
TINEGYEYNKQKDTLPLLTMATDKLEKDGYLLKLIAESLNVKEKEIVDFDLFVYEYEKGCLFGMNEEFISAGRLDDLWMV
YAGLVALLQSKSNKATKVLVALDNEEIGSLTSQGANSSLLENILERITLALGKDREDFKRSLSNSVMISADLAHALHPNY
IEKHDPTNRPLVGKGPVIKIAASGSYSTDSYAAAIFKQVCKNADVPCQEFVNRSDVKGGTTIGPITASKLNIPVIDMGAP
LLSMHSVRELASVKDNEYTIKAFTEFLSL

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=449, Percent_Identity=38.7527839643653, Blast_Score=328, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17552916, Length=434, Percent_Identity=38.4792626728111, Blast_Score=294, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6321905, Length=460, Percent_Identity=38.2608695652174, Blast_Score=320, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6322746, Length=455, Percent_Identity=30.1098901098901, Blast_Score=207, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 47450; Mature: 47450

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAKDLLNFINNSKSAFHSAHEVKSILDKEGFVEIKECDKWDLKHGGKYYVMKNESAII
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCEEE
GFEIGSGDIAEEGFRLIGAHTDSPGFRIKPHAEMTVEDHYVKLNTEVYGGAILSTWFDRP
EEEECCCCHHHCCCEEEEECCCCCCCEECCCCCEEEECEEEEEECEECCCHHHHHHHCCC
LSIAGRVTLKGSNPLKPQVKLVDLNKPVLIIPSLAIHMNRTINEGYEYNKQKDTLPLLTM
CCEEEEEEECCCCCCCCCEEEEECCCCEEEECCCEEEECCHHHCCCCCCCCCCCCEEEEE
ATDKLEKDGYLLKLIAESLNVKEKEIVDFDLFVYEYEKGCLFGMNEEFISAGRLDDLWMV
HHHHHCCCCHHHHHHHHHHCCCHHHEEEEEEEEEEECCCCEECCCHHHHCCCCCHHHHHH
YAGLVALLQSKSNKATKVLVALDNEEIGSLTSQGANSSLLENILERITLALGKDREDFKR
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
SLSNSVMISADLAHALHPNYIEKHDPTNRPLVGKGPVIKIAASGSYSTDSYAAAIFKQVC
HHCCCEEEEEHHHHHCCCCCHHCCCCCCCCEECCCCEEEEEECCCCCCHHHHHHHHHHHH
KNADVPCQEFVNRSDVKGGTTIGPITASKLNIPVIDMGAPLLSMHSVRELASVKDNEYTI
CCCCCCHHHHCCCCCCCCCCEECCEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCHH
KAFTEFLSL
HHHHHHHCC
>Mature Secondary Structure
MNTAKDLLNFINNSKSAFHSAHEVKSILDKEGFVEIKECDKWDLKHGGKYYVMKNESAII
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEECCCEEE
GFEIGSGDIAEEGFRLIGAHTDSPGFRIKPHAEMTVEDHYVKLNTEVYGGAILSTWFDRP
EEEECCCCHHHCCCEEEEECCCCCCCEECCCCCEEEECEEEEEECEECCCHHHHHHHCCC
LSIAGRVTLKGSNPLKPQVKLVDLNKPVLIIPSLAIHMNRTINEGYEYNKQKDTLPLLTM
CCEEEEEEECCCCCCCCCEEEEECCCCEEEECCCEEEECCHHHCCCCCCCCCCCCEEEEE
ATDKLEKDGYLLKLIAESLNVKEKEIVDFDLFVYEYEKGCLFGMNEEFISAGRLDDLWMV
HHHHHCCCCHHHHHHHHHHCCCHHHEEEEEEEEEEECCCCEECCCHHHHCCCCCHHHHHH
YAGLVALLQSKSNKATKVLVALDNEEIGSLTSQGANSSLLENILERITLALGKDREDFKR
HHHHHHHHHCCCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
SLSNSVMISADLAHALHPNYIEKHDPTNRPLVGKGPVIKIAASGSYSTDSYAAAIFKQVC
HHCCCEEEEEHHHHHCCCCCHHCCCCCCCCEECCCCEEEEEECCCCCCHHHHHHHHHHHH
KNADVPCQEFVNRSDVKGGTTIGPITASKLNIPVIDMGAPLLSMHSVRELASVKDNEYTI
CCCCCCHHHHCCCCCCCCCCEECCEEECCCCCCEEECCCCHHHHHHHHHHHHCCCCCCHH
KAFTEFLSL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA