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The map label for this gene is xylR [H]

Identifier: 187932917

GI number: 187932917

Start: 3508084

End: 3509211

Strand: Reverse

Name: xylR [H]

Synonym: CLL_A3335

Alternate gene names: 187932917

Gene position: 3509211-3508084 (Counterclockwise)

Preceding gene: 187933683

Following gene: 187932577

Centisome position: 92.34

GC content: 31.74

Gene sequence:

>1128_bases
ATGATTAAAAAACAAGTTAATAATATGGAAGTAAAAAAGAATAATAGAAATCGTATCTTCCGATATCTTTGTAAATGTGA
TAAGACTTCGAATTCTGAAATTGCTTATGAACTTAAGATGAGTGTGCCTACAGTAGCACAGAATACTAAAGAGTTAATGG
AGCGTGGTTTGATTGAAGAAACAGGAGAGTTTCAGTCTACTGGAGGAAGGAGAGCAAAAGCATTTTCTGTTATTTCTGAT
TCTAGATTAGCAGTTGGTCTGGATATTACAAAAAATCATTTTGGGTTGTTGTTGACAAATCTTAAAGGGGAAATTTTGAA
ATATGATCGTTTCGATTATCAATATAGTAATGACAAACTCTATTATTGTGAGATAGACAAAAAGATAGAGGAGTTTTTAG
GGAAGAATCTTAGAAACAGGGAAACAATTCTTGGAATTGGAATTTCTTTTCCTGGAATTGTAAACTTAGAGAAAGAGATT
GTTTCATATTCACATATGTTAGGGTTACAAACATTATTATTCACAGAAGTAAGCCAATTCTTTTCTTATCCATGCTGTTT
TCTTAATGATGCTAACGCAGGAGCATATGCGGAGGGGATTAATAAGGAATTTCAAAAAAGATTTTTCTATTTATCATTAA
GCAATACAGTAGGAGGAGCTATTTTTAATTGTGATGAACTAATCCAAGGGGAGAATTTCCGATGTGGAGAGGTTGGACAT
ATTACGGTTATTCCAGATGGAGTACCATGTTATTGTGGAAAATTAGGTTGTTTAGATGTATATTGCTCAGCAAAAAATTT
ATCTGATGTTACAGATGGTAAATTGTCACTTTTCTTTACAGCATTAGAACGAAAAGAAAAAGAAATCCTTAAGATATGGG
ATAAGTATACCACCTATCTATCAGTGGCTATTAATAATATTCATATGGTTTTAGATTGTGATATTATTCTTGGAGGATAC
GTAGGAAGTTATTTAGAAAATCATATTAATGACATAAGACAGAAAGTGTTACAAAGAAATACATTTTCAGAAGATGGTAT
GTTTGTGAAAACGTGTAATTATAAAGTTGGTGCAGCAGCTTTTGGGGCTGCGTTGAAAGTAATAGAAGCATTTATTAAAC
AGGTATAA

Upstream 100 bases:

>100_bases
TCAAAGGATATAAAAAAGAATATTACTTAATATAAATTGCACTTTAAAGACAGAAATGCTATACTAAAGAAACTACTTTT
ATAAAGTATAGAGGTGTGTG

Downstream 100 bases:

>100_bases
TGTTAAAATATGGTCAAAGAGAGGTCTCGTAATAGAGAACTCTTTTTTTTATATCCATAATCGGTAAATATAATTTTAAT
AGTTTATTAAATGTCTGTAT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIKKQVNNMEVKKNNRNRIFRYLCKCDKTSNSEIAYELKMSVPTVAQNTKELMERGLIEETGEFQSTGGRRAKAFSVISD
SRLAVGLDITKNHFGLLLTNLKGEILKYDRFDYQYSNDKLYYCEIDKKIEEFLGKNLRNRETILGIGISFPGIVNLEKEI
VSYSHMLGLQTLLFTEVSQFFSYPCCFLNDANAGAYAEGINKEFQKRFFYLSLSNTVGGAIFNCDELIQGENFRCGEVGH
ITVIPDGVPCYCGKLGCLDVYCSAKNLSDVTDGKLSLFFTALERKEKEILKIWDKYTTYLSVAINNIHMVLDCDIILGGY
VGSYLENHINDIRQKVLQRNTFSEDGMFVKTCNYKVGAAAFGAALKVIEAFIKQV

Sequences:

>Translated_375_residues
MIKKQVNNMEVKKNNRNRIFRYLCKCDKTSNSEIAYELKMSVPTVAQNTKELMERGLIEETGEFQSTGGRRAKAFSVISD
SRLAVGLDITKNHFGLLLTNLKGEILKYDRFDYQYSNDKLYYCEIDKKIEEFLGKNLRNRETILGIGISFPGIVNLEKEI
VSYSHMLGLQTLLFTEVSQFFSYPCCFLNDANAGAYAEGINKEFQKRFFYLSLSNTVGGAIFNCDELIQGENFRCGEVGH
ITVIPDGVPCYCGKLGCLDVYCSAKNLSDVTDGKLSLFFTALERKEKEILKIWDKYTTYLSVAINNIHMVLDCDIILGGY
VGSYLENHINDIRQKVLQRNTFSEDGMFVKTCNYKVGAAAFGAALKVIEAFIKQV
>Mature_375_residues
MIKKQVNNMEVKKNNRNRIFRYLCKCDKTSNSEIAYELKMSVPTVAQNTKELMERGLIEETGEFQSTGGRRAKAFSVISD
SRLAVGLDITKNHFGLLLTNLKGEILKYDRFDYQYSNDKLYYCEIDKKIEEFLGKNLRNRETILGIGISFPGIVNLEKEI
VSYSHMLGLQTLLFTEVSQFFSYPCCFLNDANAGAYAEGINKEFQKRFFYLSLSNTVGGAIFNCDELIQGENFRCGEVGH
ITVIPDGVPCYCGKLGCLDVYCSAKNLSDVTDGKLSLFFTALERKEKEILKIWDKYTTYLSVAINNIHMVLDCDIILGGY
VGSYLENHINDIRQKVLQRNTFSEDGMFVKTCNYKVGAAAFGAALKVIEAFIKQV

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=289, Percent_Identity=30.1038062283737, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI298566315, Length=289, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4885285, Length=289, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI190014632, Length=289, Percent_Identity=30.1038062283737, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786891, Length=268, Percent_Identity=24.6268656716418, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787878, Length=282, Percent_Identity=20.5673758865248, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082230, Length=187, Percent_Identity=25.1336898395722, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42462; Mature: 42462

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKQVNNMEVKKNNRNRIFRYLCKCDKTSNSEIAYELKMSVPTVAQNTKELMERGLIEE
CCCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHH
TGEFQSTGGRRAKAFSVISDSRLAVGLDITKNHFGLLLTNLKGEILKYDRFDYQYSNDKL
CCCHHCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEECCCCCEEEEECCCEEECCCEE
YYCEIDKKIEEFLGKNLRNRETILGIGISFPGIVNLEKEIVSYSHMLGLQTLLFTEVSQF
EEEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FSYPCCFLNDANAGAYAEGINKEFQKRFFYLSLSNTVGGAIFNCDELIQGENFRCGEVGH
HCCCEEEEECCCCCHHHHHCCHHHHHEEEEEEECCCCCCEEECHHHHHCCCCCCCCCCCE
ITVIPDGVPCYCGKLGCLDVYCSAKNLSDVTDGKLSLFFTALERKEKEILKIWDKYTTYL
EEEECCCCCHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAINNIHMVLDCDIILGGYVGSYLENHINDIRQKVLQRNTFSEDGMFVKTCNYKVGAAA
EEEECCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHH
FGAALKVIEAFIKQV
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKKQVNNMEVKKNNRNRIFRYLCKCDKTSNSEIAYELKMSVPTVAQNTKELMERGLIEE
CCCCCCCCCEECCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHH
TGEFQSTGGRRAKAFSVISDSRLAVGLDITKNHFGLLLTNLKGEILKYDRFDYQYSNDKL
CCCHHCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEECCCCCEEEEECCCEEECCCEE
YYCEIDKKIEEFLGKNLRNRETILGIGISFPGIVNLEKEIVSYSHMLGLQTLLFTEVSQF
EEEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FSYPCCFLNDANAGAYAEGINKEFQKRFFYLSLSNTVGGAIFNCDELIQGENFRCGEVGH
HCCCEEEEECCCCCHHHHHCCHHHHHEEEEEEECCCCCCEEECHHHHHCCCCCCCCCCCE
ITVIPDGVPCYCGKLGCLDVYCSAKNLSDVTDGKLSLFFTALERKEKEILKIWDKYTTYL
EEEECCCCCHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAINNIHMVLDCDIILGGYVGSYLENHINDIRQKVLQRNTFSEDGMFVKTCNYKVGAAA
EEEECCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHH
FGAALKVIEAFIKQV
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]