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The map label for this gene is 187932417

Identifier: 187932417

GI number: 187932417

Start: 1407313

End: 1408599

Strand: Reverse

Name: 187932417

Synonym: CLL_A1370

Alternate gene names: NA

Gene position: 1408599-1407313 (Counterclockwise)

Preceding gene: 187933180

Following gene: 187934345

Centisome position: 37.07

GC content: 30.15

Gene sequence:

>1287_bases
ATGAATAATATTATTGATTTATTAGTTATTGGCGCTGGACCAGCAGGACTTATGACTGCAAAAACTGCAGCAGAATTAGG
ATTGAAGGTTACACTTATTGAAAAGAATAGAAATTTTGAACAATTACGTCGAGCATGTTCTGCTCAATTTATTTTAGATG
ATGGTTATGAAAATGAATTTATTAAATTAGAAGATGGAAAAATATTATTTACAAAGAATAATTTCGAAGTTAATTACACT
GGGGCTTTAGTTGATGTTAAGAATAAATACTATAAATCTCCTAATGGTCATAAAATTCATTTTGCTCTTCCAGGTCAAAA
AGCATTTGCTGTAAAATTTGATAAACGAAAACTTCTTGATGATTTATATAAAGAATGTGTAAATTTAGGCGTTGATATTA
GACTGTCAACTTTAGCATCTGGAGGATCCGATAATGGTGACTGCGTAAGCATAAATCTTAAAGATAATAATAATAGTTAT
ACTTTAAATGCAAAAAAAGTTGTTATTGCTGAGGGCGCAAATGCACATTTAACTGGCCTATTCGGTTTTAATAAAGGTAG
AACTAACTTTGCTACAGCTCTTGTAGTAAAATATATACTTGAAGGTATATCAGGAATTGAACCAAATAGCTGGAATCTTT
TTTATGGGAAAGCATTTTTTTCTAATGCACCAATAATTATAGGGCCTAGCTTATATGGAAATAATACTTTTGAACTAACA
ATTTCAGGTTCTGCAAATGCAAGACCAGATTCAATTTATGAAAATGTTGTTAAGAACAGTCCACTTAAAAAGAATTTTGA
AGCTGCTAAGTTAATAGATAAACAAGGCTGTGCTGTAAAAGCTTTTTCATCACTAAAAACACCTTATAGTGGTAATGTTC
TTGTAATTGGTGATAGTGCTGCCTTCGTTGAAGTTGAAGTTCAAGGTGGATTAATGTGTGGGTATCATGCAGCAAATGCA
ATAAATGAAGAACTACAAGGAAAGAATGGTTTTGAAGATTACACTAATTGGTGGAAAAACGCTTTTGAATTTAATAGTGA
TGAATATCTTTTAGTATCTCAAGGTTATGCACTTGTACCAACATATACTGACGATGAACTTGATTATCTTTTCTCTCTTG
TTGAAGGAAAAACATTAGAAGGAACTTACAGCCAATATAAAACTCCAAAACTTATTTGGGATGCAATTTTATTGCATAAA
GACAAAATTCAAAGTGAAAGACCTATTATATATGAAAAAATCAAAAAAATGAATACTATGACTTTAACAGATACATTTAA
TAATTAA

Upstream 100 bases:

>100_bases
AGGTAGCCTACCTATTTAAATTTTATAAAAACATTATTTTTACCAATAAGTAAAAATACACTATATTTATAGTTAAGAAA
TTAAGGAGATGTTAAGAATT

Downstream 100 bases:

>100_bases
TTTGAGAGGAGCTATAATATGGAAAATATGATTGATTTAATCGTAGTTGGTGCAGGACCTGCAGGACTAATGACTGCAAA
AAGAGCAGCAGAATTAGGTT

Product: pyridine nucleotide-disulphide oxidoreductase domain protein

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNNIIDLLVIGAGPAGLMTAKTAAELGLKVTLIEKNRNFEQLRRACSAQFILDDGYENEFIKLEDGKILFTKNNFEVNYT
GALVDVKNKYYKSPNGHKIHFALPGQKAFAVKFDKRKLLDDLYKECVNLGVDIRLSTLASGGSDNGDCVSINLKDNNNSY
TLNAKKVVIAEGANAHLTGLFGFNKGRTNFATALVVKYILEGISGIEPNSWNLFYGKAFFSNAPIIIGPSLYGNNTFELT
ISGSANARPDSIYENVVKNSPLKKNFEAAKLIDKQGCAVKAFSSLKTPYSGNVLVIGDSAAFVEVEVQGGLMCGYHAANA
INEELQGKNGFEDYTNWWKNAFEFNSDEYLLVSQGYALVPTYTDDELDYLFSLVEGKTLEGTYSQYKTPKLIWDAILLHK
DKIQSERPIIYEKIKKMNTMTLTDTFNN

Sequences:

>Translated_428_residues
MNNIIDLLVIGAGPAGLMTAKTAAELGLKVTLIEKNRNFEQLRRACSAQFILDDGYENEFIKLEDGKILFTKNNFEVNYT
GALVDVKNKYYKSPNGHKIHFALPGQKAFAVKFDKRKLLDDLYKECVNLGVDIRLSTLASGGSDNGDCVSINLKDNNNSY
TLNAKKVVIAEGANAHLTGLFGFNKGRTNFATALVVKYILEGISGIEPNSWNLFYGKAFFSNAPIIIGPSLYGNNTFELT
ISGSANARPDSIYENVVKNSPLKKNFEAAKLIDKQGCAVKAFSSLKTPYSGNVLVIGDSAAFVEVEVQGGLMCGYHAANA
INEELQGKNGFEDYTNWWKNAFEFNSDEYLLVSQGYALVPTYTDDELDYLFSLVEGKTLEGTYSQYKTPKLIWDAILLHK
DKIQSERPIIYEKIKKMNTMTLTDTFNN
>Mature_428_residues
MNNIIDLLVIGAGPAGLMTAKTAAELGLKVTLIEKNRNFEQLRRACSAQFILDDGYENEFIKLEDGKILFTKNNFEVNYT
GALVDVKNKYYKSPNGHKIHFALPGQKAFAVKFDKRKLLDDLYKECVNLGVDIRLSTLASGGSDNGDCVSINLKDNNNSY
TLNAKKVVIAEGANAHLTGLFGFNKGRTNFATALVVKYILEGISGIEPNSWNLFYGKAFFSNAPIIIGPSLYGNNTFELT
ISGSANARPDSIYENVVKNSPLKKNFEAAKLIDKQGCAVKAFSSLKTPYSGNVLVIGDSAAFVEVEVQGGLMCGYHAANA
INEELQGKNGFEDYTNWWKNAFEFNSDEYLLVSQGYALVPTYTDDELDYLFSLVEGKTLEGTYSQYKTPKLIWDAILLHK
DKIQSERPIIYEKIKKMNTMTLTDTFNN

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: NA

Molecular weight: Translated: 47460; Mature: 47460

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIIDLLVIGAGPAGLMTAKTAAELGLKVTLIEKNRNFEQLRRACSAQFILDDGYENEF
CCCEEEEEEECCCCCCCEEHHHHHHCCEEEEEEECCCCHHHHHHHHCEEEEEECCCCCCE
IKLEDGKILFTKNNFEVNYTGALVDVKNKYYKSPNGHKIHFALPGQKAFAVKFDKRKLLD
EEEECCEEEEEECCEEEEEEEEEEEECHHHCCCCCCCEEEEEECCCEEEEEEEHHHHHHH
DLYKECVNLGVDIRLSTLASGGSDNGDCVSINLKDNNNSYTLNAKKVVIAEGANAHLTGL
HHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCEEEEE
FGFNKGRTNFATALVVKYILEGISGIEPNSWNLFYGKAFFSNAPIIIGPSLYGNNTFELT
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCEEECCCCCCCCEEEEE
ISGSANARPDSIYENVVKNSPLKKNFEAAKLIDKQGCAVKAFSSLKTPYSGNVLVIGDSA
ECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEHHHCCCCCCCCEEEEECCC
AFVEVEVQGGLMCGYHAANAINEELQGKNGFEDYTNWWKNAFEFNSDEYLLVSQGYALVP
EEEEEEECCCEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEE
TYTDDELDYLFSLVEGKTLEGTYSQYKTPKLIWDAILLHKDKIQSERPIIYEKIKKMNTM
ECCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEE
TLTDTFNN
EEEECCCC
>Mature Secondary Structure
MNNIIDLLVIGAGPAGLMTAKTAAELGLKVTLIEKNRNFEQLRRACSAQFILDDGYENEF
CCCEEEEEEECCCCCCCEEHHHHHHCCEEEEEEECCCCHHHHHHHHCEEEEEECCCCCCE
IKLEDGKILFTKNNFEVNYTGALVDVKNKYYKSPNGHKIHFALPGQKAFAVKFDKRKLLD
EEEECCEEEEEECCEEEEEEEEEEEECHHHCCCCCCCEEEEEECCCEEEEEEEHHHHHHH
DLYKECVNLGVDIRLSTLASGGSDNGDCVSINLKDNNNSYTLNAKKVVIAEGANAHLTGL
HHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCEEEEE
FGFNKGRTNFATALVVKYILEGISGIEPNSWNLFYGKAFFSNAPIIIGPSLYGNNTFELT
EECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCEEECCCCCCCCEEEEE
ISGSANARPDSIYENVVKNSPLKKNFEAAKLIDKQGCAVKAFSSLKTPYSGNVLVIGDSA
ECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCEEEEHHHCCCCCCCCEEEEECCC
AFVEVEVQGGLMCGYHAANAINEELQGKNGFEDYTNWWKNAFEFNSDEYLLVSQGYALVP
EEEEEEECCCEEECHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEE
TYTDDELDYLFSLVEGKTLEGTYSQYKTPKLIWDAILLHKDKIQSERPIIYEKIKKMNTM
ECCCCHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEE
TLTDTFNN
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]