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The map label for this gene is 187918542

Identifier: 187918542

GI number: 187918542

Start: 733754

End: 734692

Strand: Direct

Name: 187918542

Synonym: BH0686

Alternate gene names: NA

Gene position: 733754-734692 (Clockwise)

Preceding gene: 187918541

Following gene: 187918543

Centisome position: 79.56

GC content: 31.52

Gene sequence:

>939_bases
GTGAAGATTAGATGTAAGGCAAATCCTAGTTTGGCGTTAATTAAGTATTGGGGCAAGAGAGATAAATTTTTGAATATTCC
AGCTACTTCAAGCATTGCCGTAAGTGTTGATAAATTTTATTCAATAAGCGAACTTGAATTATCATGTAAGGATGAAATAA
TTTTAAATTCAAGGGCTATTGTATTACAAGAGAGGGAAATAAATTTTTTTAATTATGCAAGGAAAATTTTAAATGAGCCA
AATGTTGGATTTAGGGTAATTAGTGAAAATAATTTTCCAACAGCCGCAGGACTTGCAAGTTCAAGCTCTGGGTTTGCATC
TATTGCTGCTTGTATTTTAAGATATTTTAATCAATATTCCCATCAAAAAGCTTCACAGCTTGCAAGAATAGGCTCAGCTT
CAGCGGCAAGAGCTATTTATGGTGGATTTACCTTTTTAAAGGAAGGGGCCAGGAGTGCATTTCAGTTAAATAATTTTAAT
TATTTTAATGATTTGTGCATAATATTTGCTATAGTTGATAGCAGAAAAAAAGATATGTCTTCAAGGGCTGCCATGGAGAT
TTGCAAGCAGGAGAAATTTTATTGGGATGCTTGGATTAAGTCTAGTCGAAATATATTTAAAGAAGCTTTATTTTTTTTGT
TAAAAGGAGATTTTAACGAATTTGGTCTTAAGATTGTAAAAAGTTATCAGTGTATGTTTGCTTTAATGTTATCATCTTCC
ATTATTTATTTTAAAAGTAATACTATAGAGTTAATAAAGTATATTGCTGCTCTTAGAAGTAGAGGTATTTCTGTTTTTGA
AACGATGGATGCTGGGCCACAGGTTAAGGTGTTGTGCCTAAAGAAAGATTTGGAATTAGTTTTAACTGAACTTACTAGCA
ATTTTAGAGATGTTGATTTTATTGTTTCAAGGATTGGAAGTGGTTTGGAATGGATATAA

Upstream 100 bases:

>100_bases
TCAAGTGATGAGATAGAAAAAATATTATTGAAAATGAGTGACAGTGGAATTTATTCTCTTGATTTTGCTCTTAAACTTTT
AAAGGATTTGCGAGTGTAGT

Downstream 100 bases:

>100_bases
TTAATTTTTCAGTGCCTGGTAATTTACTTTTAATGGGTGAATATTTTATTTTGGAAGAAAATGGTCTTGGACTTGCAATT
GCAATCAAAGAAAGAGCTTA

Product: diphosphomevalonate decarboxylase

Products: NA

Alternate protein names: Mevalonate Pyrophosphate Decarboxylase; Mevalonate Diphosphate Decarboxylase

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKIRCKANPSLALIKYWGKRDKFLNIPATSSIAVSVDKFYSISELELSCKDEIILNSRAIVLQEREINFFNYARKILNEP
NVGFRVISENNFPTAAGLASSSSGFASIAACILRYFNQYSHQKASQLARIGSASAARAIYGGFTFLKEGARSAFQLNNFN
YFNDLCIIFAIVDSRKKDMSSRAAMEICKQEKFYWDAWIKSSRNIFKEALFFLLKGDFNEFGLKIVKSYQCMFALMLSSS
IIYFKSNTIELIKYIAALRSRGISVFETMDAGPQVKVLCLKKDLELVLTELTSNFRDVDFIVSRIGSGLEWI

Sequences:

>Translated_312_residues
MKIRCKANPSLALIKYWGKRDKFLNIPATSSIAVSVDKFYSISELELSCKDEIILNSRAIVLQEREINFFNYARKILNEP
NVGFRVISENNFPTAAGLASSSSGFASIAACILRYFNQYSHQKASQLARIGSASAARAIYGGFTFLKEGARSAFQLNNFN
YFNDLCIIFAIVDSRKKDMSSRAAMEICKQEKFYWDAWIKSSRNIFKEALFFLLKGDFNEFGLKIVKSYQCMFALMLSSS
IIYFKSNTIELIKYIAALRSRGISVFETMDAGPQVKVLCLKKDLELVLTELTSNFRDVDFIVSRIGSGLEWI
>Mature_312_residues
MKIRCKANPSLALIKYWGKRDKFLNIPATSSIAVSVDKFYSISELELSCKDEIILNSRAIVLQEREINFFNYARKILNEP
NVGFRVISENNFPTAAGLASSSSGFASIAACILRYFNQYSHQKASQLARIGSASAARAIYGGFTFLKEGARSAFQLNNFN
YFNDLCIIFAIVDSRKKDMSSRAAMEICKQEKFYWDAWIKSSRNIFKEALFFLLKGDFNEFGLKIVKSYQCMFALMLSSS
IIYFKSNTIELIKYIAALRSRGISVFETMDAGPQVKVLCLKKDLELVLTELTSNFRDVDFIVSRIGSGLEWI

Specific function: Unknown

COG id: COG3407

COG function: function code I; Mevalonate pyrophosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4505289, Length=313, Percent_Identity=29.073482428115, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537201, Length=339, Percent_Identity=29.4985250737463, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324371, Length=203, Percent_Identity=31.5270935960591, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571205, Length=327, Percent_Identity=26.605504587156, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35362; Mature: 35362

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRCKANPSLALIKYWGKRDKFLNIPATSSIAVSVDKFYSISELELSCKDEIILNSRAI
CEEEECCCCCEEEEEECCCCCCEEECCCCCCEEEEHHHHCCHHHHEECCCCCEEECCCEE
VLQEREINFFNYARKILNEPNVGFRVISENNFPTAAGLASSSSGFASIAACILRYFNQYS
EEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHH
HQKASQLARIGSASAARAIYGGFTFLKEGARSAFQLNNFNYFNDLCIIFAIVDSRKKDMS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHH
SRAAMEICKQEKFYWDAWIKSSRNIFKEALFFLLKGDFNEFGLKIVKSYQCMFALMLSSS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
IIYFKSNTIELIKYIAALRSRGISVFETMDAGPQVKVLCLKKDLELVLTELTSNFRDVDF
EEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHH
IVSRIGSGLEWI
HHHHHCCCCCCC
>Mature Secondary Structure
MKIRCKANPSLALIKYWGKRDKFLNIPATSSIAVSVDKFYSISELELSCKDEIILNSRAI
CEEEECCCCCEEEEEECCCCCCEEECCCCCCEEEEHHHHCCHHHHEECCCCCEEECCCEE
VLQEREINFFNYARKILNEPNVGFRVISENNFPTAAGLASSSSGFASIAACILRYFNQYS
EEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHH
HQKASQLARIGSASAARAIYGGFTFLKEGARSAFQLNNFNYFNDLCIIFAIVDSRKKDMS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHH
SRAAMEICKQEKFYWDAWIKSSRNIFKEALFFLLKGDFNEFGLKIVKSYQCMFALMLSSS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
IIYFKSNTIELIKYIAALRSRGISVFETMDAGPQVKVLCLKKDLELVLTELTSNFRDVDF
EEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHH
IVSRIGSGLEWI
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA