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The map label for this gene is yqjI [H]

Identifier: 187918424

GI number: 187918424

Start: 582784

End: 584178

Strand: Direct

Name: yqjI [H]

Synonym: BH0561

Alternate gene names: 187918424

Gene position: 582784-584178 (Clockwise)

Preceding gene: 187918422

Following gene: 187918428

Centisome position: 63.19

GC content: 30.54

Gene sequence:

>1395_bases
ATGGATGTTGGTATTTATGGGCTGGGAGTTATGGGTAGCAATTTAGCGTTAAATATTGCTGATAGCGGTTTTAACGTTTC
TGTTTATAATAGAGATAGTGATAAGACGGAAATTTTCCTTGTAAATAATGCTCATAAAAAAATTCATGGGTTTAAAGATA
TTGAGACTTTTATTGGAAGTTTAAAAAAACCTAGAAAGATTATTTTAATGATATTAAGCTCAGCTGTGGATGAAGTCATT
GAACAAATTTTACCTTTAGTTGAAAAATTCGATATTATTATTGATGGTGGAAATTCTCATTATAAGGATACTGTAAGGAG
AGAGCAGGGATTATCTTCTAAGGATATTTATTTTGTAGGGCTTGGAATTTCAGGTGGTGAAAAGGGAGCAAGATTTGGAC
CTTCTTTGATGTATGGTGGTAGCAAAAAGGCTTATGGATTAATTGAGCCTATTTTAAATAAGATAGCTGCTAAGACAAGT
GTTGGGGATATTTGTTCTGCTTATGTTGGTGAGAATGGAGCTGGTCATTATGTAAAGATGATTCATAATGGGATTGAATA
TGCAGATATGCAACTCATTAGTGAAGCATATTTTTTTATGAAGAGAGCTTTTAATTTAGATAATTTAAGAATTTCTGAAG
TATTTGACAAGTGGGGAGAAGGTGATCTCTCTAGTTATTTGATAGAAATAACATCTAATATTTTAAAATATAAGGAAAAT
AATGAATATTTACTTGATAAGATTTTAGATGTTGCAAATCAAAAAGGTACTGGTAAGTGGGTATCAATTGAAGCTTTACA
ATTAAATGTACCAGCAAATTTGATTTTTGAATCTGTATTTGCAAGGTTTTTATCAGGATTAAAACATGAACGAGTAATTG
CTAGTGATATCCTTAAAATGGACGTGGATTCTGCTGAATTCGATCTTAGTGATTGGATTTTAGATCTTTATTATGCTCTT
TTGGTTTCCAAGATATTAGCTTATGTTCAGGGTTTTATGATGCTTAAGAGTGCATCTGTTAATTATTCTTGGGACTTAAA
TTTAGGAAAGATTTCTTTGATTTGGAGAGAGGGTTGTATAATTAAAAGCGTTTTCTTAGATAAGATTAAATTAGCTTATG
ATAAGAACCCGCATCTAATTAATTTACTTTTTGATGATTATTTTTTGGATATAATAAGAAATCATCAAAAATCTTTAAGG
CGCATAGTTTCAAAAGCTAGTGAGATTGGAATACCTTTGCCAGCATTTTATGCAAGTCTTTCTTTTCTAGATTCTTATTC
TACTAATTATTTGCCAGCCAATTTAATTCAGGCTCAAAGAGATTTTTTTGGTGCACATAGTTTTGAAAGAATTGATTCAA
AGAGAGGTGAATTTTTTCATAGTACTTGGAGATAA

Upstream 100 bases:

>100_bases
TTTGTTTTAATCTTTACTTTTTTTATAATATATCATAATCTAAAAATAATGAATAAAATAAATTTGTCTATAATAAAAAA
TTAGTGTAGGGGATAATACT

Downstream 100 bases:

>100_bases
TTTGAGTTTAGTATTTTAAATATAATATTTGACGAATATTCCACCCATTATATTTGTTTTAAGTCCTGCATAGAAGTAAT
GATATGCAATGGATTTTGCG

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MDVGIYGLGVMGSNLALNIADSGFNVSVYNRDSDKTEIFLVNNAHKKIHGFKDIETFIGSLKKPRKIILMILSSAVDEVI
EQILPLVEKFDIIIDGGNSHYKDTVRREQGLSSKDIYFVGLGISGGEKGARFGPSLMYGGSKKAYGLIEPILNKIAAKTS
VGDICSAYVGENGAGHYVKMIHNGIEYADMQLISEAYFFMKRAFNLDNLRISEVFDKWGEGDLSSYLIEITSNILKYKEN
NEYLLDKILDVANQKGTGKWVSIEALQLNVPANLIFESVFARFLSGLKHERVIASDILKMDVDSAEFDLSDWILDLYYAL
LVSKILAYVQGFMMLKSASVNYSWDLNLGKISLIWREGCIIKSVFLDKIKLAYDKNPHLINLLFDDYFLDIIRNHQKSLR
RIVSKASEIGIPLPAFYASLSFLDSYSTNYLPANLIQAQRDFFGAHSFERIDSKRGEFFHSTWR

Sequences:

>Translated_464_residues
MDVGIYGLGVMGSNLALNIADSGFNVSVYNRDSDKTEIFLVNNAHKKIHGFKDIETFIGSLKKPRKIILMILSSAVDEVI
EQILPLVEKFDIIIDGGNSHYKDTVRREQGLSSKDIYFVGLGISGGEKGARFGPSLMYGGSKKAYGLIEPILNKIAAKTS
VGDICSAYVGENGAGHYVKMIHNGIEYADMQLISEAYFFMKRAFNLDNLRISEVFDKWGEGDLSSYLIEITSNILKYKEN
NEYLLDKILDVANQKGTGKWVSIEALQLNVPANLIFESVFARFLSGLKHERVIASDILKMDVDSAEFDLSDWILDLYYAL
LVSKILAYVQGFMMLKSASVNYSWDLNLGKISLIWREGCIIKSVFLDKIKLAYDKNPHLINLLFDDYFLDIIRNHQKSLR
RIVSKASEIGIPLPAFYASLSFLDSYSTNYLPANLIQAQRDFFGAHSFERIDSKRGEFFHSTWR
>Mature_464_residues
MDVGIYGLGVMGSNLALNIADSGFNVSVYNRDSDKTEIFLVNNAHKKIHGFKDIETFIGSLKKPRKIILMILSSAVDEVI
EQILPLVEKFDIIIDGGNSHYKDTVRREQGLSSKDIYFVGLGISGGEKGARFGPSLMYGGSKKAYGLIEPILNKIAAKTS
VGDICSAYVGENGAGHYVKMIHNGIEYADMQLISEAYFFMKRAFNLDNLRISEVFDKWGEGDLSSYLIEITSNILKYKEN
NEYLLDKILDVANQKGTGKWVSIEALQLNVPANLIFESVFARFLSGLKHERVIASDILKMDVDSAEFDLSDWILDLYYAL
LVSKILAYVQGFMMLKSASVNYSWDLNLGKISLIWREGCIIKSVFLDKIKLAYDKNPHLINLLFDDYFLDIIRNHQKSLR
RIVSKASEIGIPLPAFYASLSFLDSYSTNYLPANLIQAQRDFFGAHSFERIDSKRGEFFHSTWR

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=466, Percent_Identity=50.8583690987124, Blast_Score=453, Evalue=1e-127,
Organism=Escherichia coli, GI1788341, Length=465, Percent_Identity=49.4623655913978, Blast_Score=466, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17542558, Length=468, Percent_Identity=49.3589743589744, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6321695, Length=453, Percent_Identity=52.0971302428256, Blast_Score=455, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6321977, Length=454, Percent_Identity=52.2026431718062, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24639279, Length=465, Percent_Identity=50.1075268817204, Blast_Score=439, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 52337; Mature: 52337

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVGIYGLGVMGSNLALNIADSGFNVSVYNRDSDKTEIFLVNNAHKKIHGFKDIETFIGS
CCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCEEEEEEECCHHHHCCHHHHHHHHHC
LKKPRKIILMILSSAVDEVIEQILPLVEKFDIIIDGGNSHYKDTVRREQGLSSKDIYFVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCEEEEE
LGISGGEKGARFGPSLMYGGSKKAYGLIEPILNKIAAKTSVGDICSAYVGENGAGHYVKM
EECCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHH
IHNGIEYADMQLISEAYFFMKRAFNLDNLRISEVFDKWGEGDLSSYLIEITSNILKYKEN
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
NEYLLDKILDVANQKGTGKWVSIEALQLNVPANLIFESVFARFLSGLKHERVIASDILKM
CHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DVDSAEFDLSDWILDLYYALLVSKILAYVQGFMMLKSASVNYSWDLNLGKISLIWREGCI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCH
IKSVFLDKIKLAYDKNPHLINLLFDDYFLDIIRNHQKSLRRIVSKASEIGIPLPAFYASL
HHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SFLDSYSTNYLPANLIQAQRDFFGAHSFERIDSKRGEFFHSTWR
HHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MDVGIYGLGVMGSNLALNIADSGFNVSVYNRDSDKTEIFLVNNAHKKIHGFKDIETFIGS
CCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCEEEEEEECCHHHHCCHHHHHHHHHC
LKKPRKIILMILSSAVDEVIEQILPLVEKFDIIIDGGNSHYKDTVRREQGLSSKDIYFVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHCCCCCCEEEEE
LGISGGEKGARFGPSLMYGGSKKAYGLIEPILNKIAAKTSVGDICSAYVGENGAGHYVKM
EECCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHH
IHNGIEYADMQLISEAYFFMKRAFNLDNLRISEVFDKWGEGDLSSYLIEITSNILKYKEN
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
NEYLLDKILDVANQKGTGKWVSIEALQLNVPANLIFESVFARFLSGLKHERVIASDILKM
CHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DVDSAEFDLSDWILDLYYALLVSKILAYVQGFMMLKSASVNYSWDLNLGKISLIWREGCI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCH
IKSVFLDKIKLAYDKNPHLINLLFDDYFLDIIRNHQKSLRRIVSKASEIGIPLPAFYASL
HHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SFLDSYSTNYLPANLIQAQRDFFGAHSFERIDSKRGEFFHSTWR
HHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]