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The map label for this gene is 187918370

Identifier: 187918370

GI number: 187918370

Start: 514502

End: 516043

Strand: Direct

Name: 187918370

Synonym: BH0504

Alternate gene names: NA

Gene position: 514502-516043 (Clockwise)

Preceding gene: 187918369

Following gene: 187918371

Centisome position: 55.78

GC content: 33.4

Gene sequence:

>1542_bases
ATGTCATATATTACTTTTTCTTCTATTCTTGCTGGTATTTTAGGTATTGTATTAGGTTTTGTAATAAGAATTATTTTAGG
TAGATTTTCTTTATTAAATTTAGATAAAAAGCTAAAGAAGGTACAAGAAGAGGCAATCTTAGAGATAGAAAATGAAAGAA
AACGAGTTATTTCGCATACAAAAGCCCAAATGCTTAAAGAGAAGAATCAGCAAGATAGGGAAATAAGAGAACGAAAAAAT
GAAGTTTTTAATTTAGAGAGAAGATTATTACAAAGAGAAGAGACTTTAGATAAGAGAATATCAGCTCTTGATAAGCAGCA
GAGTAGGATTGATTTTAAGCTTAAAGAATTTGAGCAAAAAGAAAAAATTATACGAGATAAGGAATTATCTCTTGTTAAAA
AGTTAGAAAATATTGCTGGTCTTACAAAAGAAGAAGCAAGAAAGATTGTAATTGAAAGAGTTGAAAATGAATCTAAAAGA
GATGCTCAGATTATTATTAATAAAAGTGAGCAAGAGGCTCAACTTTTAGCAGATAAGGTAGCTAAAGATATATTGGTCTC
TACTATGCAACGCATAGTAACAGAGGTCAGCTCTGAGTTTACAGTTACTGCTGTTGAACTGCCTAATGATGAGATGAAAG
GTAGAATCATCGGCAAAGAAGGACGTAATATTAGGGTTCTTGAGACATTAATAGGTGCAGATATTATTATTGATGATACT
CCTGAGGCTGTTGTTATATCTTGTTTTGATCCAGTAAGAAAAGAAATAGCTAAAAGGACCCTTGAAAGACTTGTTGCAGA
CGGGAGAATTCATCCTGCAAGAATTGAAGAGATTGTTTATAGTGTTACTAATGAGATCAATAATATTATTCTTGAGGAAG
GCGAGAAGGCAGTATTTGATTTAAATATACATGGATTTGATAAAAGACTGATTAGAGGTCTTGGAAGACTTTACTTTAGA
AGCAGTTATGGTCAGAACGTTTTAAGTCATTCAAAAGAAACAGCAATAATCGGAGAAATTTTAGCTAAAGAGATGAAATT
AGATCCTGTTGTTGTTAAAAGGGCATGTCTTTTACATGATATTGGAAAGGGCATGGAGAGTATTTCTGAGAATAGTGAGG
GACATGCTATTACAGGTGCTGAGCTTGCTCAGAGTTGTGGGGAGAGCGATATTGTCGTTAATGCTATTGCTGCACATCAT
AATGAAATAAAGCCTGAAAGTTTTGAGGCTATCATTGTCCAAATAGCTGATGCTATTTCCGCATCTCGTCCTGGTGCAAG
ACGTGAGAGTTTAAATAATTACATAAGTAGACTTAAGAGACTTGAAGAGATTGCGTATGGATTTGAGGGCGTCCAAAAAT
GTTATGCAATTCAGGCGGGTCGTGAAGTTAGAATAATTGTTGATAATTTATTGGTTAATGATGAGAAAGCTACTATGCTT
GCAAGAGATATTGCAAAAAAGATAGAAGTTGAGATGAGGTATCCTGGCAAAATAAAAGTTACTATTATTCGTGAGACTAG
AGTTATTGAGTATGCAAGATAA

Upstream 100 bases:

>100_bases
ATAAAACCTTAGAAGAAAAGTAATAGTCTTACATATTAAATATGTCCTTCTTCTAAAGGATTTATATTTAATTGGTTTGG
TGGAATAGGGGGTAAATTGT

Downstream 100 bases:

>100_bases
TGATGTTATTAGAGCTTTGATAATTGGAGATATCATAGGTGATGGGGGACTTAAAAAGATTTTTTTTAATCTTAAGAGTC
TTAAAGAGAAGTACAATATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSYITFSSILAGILGIVLGFVIRIILGRFSLLNLDKKLKKVQEEAILEIENERKRVISHTKAQMLKEKNQQDREIRERKN
EVFNLERRLLQREETLDKRISALDKQQSRIDFKLKEFEQKEKIIRDKELSLVKKLENIAGLTKEEARKIVIERVENESKR
DAQIIINKSEQEAQLLADKVAKDILVSTMQRIVTEVSSEFTVTAVELPNDEMKGRIIGKEGRNIRVLETLIGADIIIDDT
PEAVVISCFDPVRKEIAKRTLERLVADGRIHPARIEEIVYSVTNEINNIILEEGEKAVFDLNIHGFDKRLIRGLGRLYFR
SSYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGKGMESISENSEGHAITGAELAQSCGESDIVVNAIAAHH
NEIKPESFEAIIVQIADAISASRPGARRESLNNYISRLKRLEEIAYGFEGVQKCYAIQAGREVRIIVDNLLVNDEKATML
ARDIAKKIEVEMRYPGKIKVTIIRETRVIEYAR

Sequences:

>Translated_513_residues
MSYITFSSILAGILGIVLGFVIRIILGRFSLLNLDKKLKKVQEEAILEIENERKRVISHTKAQMLKEKNQQDREIRERKN
EVFNLERRLLQREETLDKRISALDKQQSRIDFKLKEFEQKEKIIRDKELSLVKKLENIAGLTKEEARKIVIERVENESKR
DAQIIINKSEQEAQLLADKVAKDILVSTMQRIVTEVSSEFTVTAVELPNDEMKGRIIGKEGRNIRVLETLIGADIIIDDT
PEAVVISCFDPVRKEIAKRTLERLVADGRIHPARIEEIVYSVTNEINNIILEEGEKAVFDLNIHGFDKRLIRGLGRLYFR
SSYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGKGMESISENSEGHAITGAELAQSCGESDIVVNAIAAHH
NEIKPESFEAIIVQIADAISASRPGARRESLNNYISRLKRLEEIAYGFEGVQKCYAIQAGREVRIIVDNLLVNDEKATML
ARDIAKKIEVEMRYPGKIKVTIIRETRVIEYAR
>Mature_512_residues
SYITFSSILAGILGIVLGFVIRIILGRFSLLNLDKKLKKVQEEAILEIENERKRVISHTKAQMLKEKNQQDREIRERKNE
VFNLERRLLQREETLDKRISALDKQQSRIDFKLKEFEQKEKIIRDKELSLVKKLENIAGLTKEEARKIVIERVENESKRD
AQIIINKSEQEAQLLADKVAKDILVSTMQRIVTEVSSEFTVTAVELPNDEMKGRIIGKEGRNIRVLETLIGADIIIDDTP
EAVVISCFDPVRKEIAKRTLERLVADGRIHPARIEEIVYSVTNEINNIILEEGEKAVFDLNIHGFDKRLIRGLGRLYFRS
SYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGKGMESISENSEGHAITGAELAQSCGESDIVVNAIAAHHN
EIKPESFEAIIVQIADAISASRPGARRESLNNYISRLKRLEEIAYGFEGVQKCYAIQAGREVRIIVDNLLVNDEKATMLA
RDIAKKIEVEMRYPGKIKVTIIRETRVIEYAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 58337; Mature: 58206

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYITFSSILAGILGIVLGFVIRIILGRFSLLNLDKKLKKVQEEAILEIENERKRVISHT
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQMLKEKNQQDREIRERKNEVFNLERRLLQREETLDKRISALDKQQSRIDFKLKEFEQK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIIRDKELSLVKKLENIAGLTKEEARKIVIERVENESKRDAQIIINKSEQEAQLLADKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHH
AKDILVSTMQRIVTEVSSEFTVTAVELPNDEMKGRIIGKEGRNIRVLETLIGADIIIDDT
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHCCCEEECCC
PEAVVISCFDPVRKEIAKRTLERLVADGRIHPARIEEIVYSVTNEINNIILEEGEKAVFD
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LNIHGFDKRLIRGLGRLYFRSSYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHD
EEECCHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGKGMESISENSEGHAITGAELAQSCGESDIVVNAIAAHHNEIKPESFEAIIVQIADAIS
HHHHHHHHHCCCCCCEEEHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ASRPGARRESLNNYISRLKRLEEIAYGFEGVQKCYAIQAGREVRIIVDNLLVNDEKATML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCHHHHHH
ARDIAKKIEVEMRYPGKIKVTIIRETRVIEYAR
HHHHHHHHEEEEECCCEEEEEEEECCCHHCCCC
>Mature Secondary Structure 
SYITFSSILAGILGIVLGFVIRIILGRFSLLNLDKKLKKVQEEAILEIENERKRVISHT
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQMLKEKNQQDREIRERKNEVFNLERRLLQREETLDKRISALDKQQSRIDFKLKEFEQK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKIIRDKELSLVKKLENIAGLTKEEARKIVIERVENESKRDAQIIINKSEQEAQLLADKV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHH
AKDILVSTMQRIVTEVSSEFTVTAVELPNDEMKGRIIGKEGRNIRVLETLIGADIIIDDT
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHCCCEEECCC
PEAVVISCFDPVRKEIAKRTLERLVADGRIHPARIEEIVYSVTNEINNIILEEGEKAVFD
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LNIHGFDKRLIRGLGRLYFRSSYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHD
EEECCHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGKGMESISENSEGHAITGAELAQSCGESDIVVNAIAAHHNEIKPESFEAIIVQIADAIS
HHHHHHHHHCCCCCCEEEHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ASRPGARRESLNNYISRLKRLEEIAYGFEGVQKCYAIQAGREVRIIVDNLLVNDEKATML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCHHHHHH
ARDIAKKIEVEMRYPGKIKVTIIRETRVIEYAR
HHHHHHHHEEEEECCCEEEEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]