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The map label for this gene is luxS [H]

Identifier: 187918244

GI number: 187918244

Start: 389608

End: 390081

Strand: Direct

Name: luxS [H]

Synonym: BH0377

Alternate gene names: 187918244

Gene position: 389608-390081 (Clockwise)

Preceding gene: 187918243

Following gene: 187918265

Centisome position: 42.24

GC content: 31.01

Gene sequence:

>474_bases
ATGAATAAAATATCGAGCTTTACAATTGATCACACAAAACTAAAACCTGGTATATATATATCAAGAAAAGATATATTTGA
AAATTTAACATGCACTACTGTAGATATTAGGATGAAAGCTCCCAATAGAGAGCCTGTAATTAATAACGCGGAAATGCATA
CAATTGAACATATAGGAGCAACACTGCTGAGAAATAATAAAGTCTGGGGCGATAAAATATTATATTTTGGGCCAATGGGC
TGTAGAACTGGATTTTACCTAATCCTTTTAGGAAACTATGAGAGCAAAGATCTTATTGATTTAATATCTTGGCTTTTTCA
TGAGATTACAAATTTTCAAGGAAATGTCACAGGAGCAACTGAAAAGGAATGTGGTAATTACCAAGATCACAATCTAAACA
TGGCAAAATATGAATCTAATCGGTATTTAACAACACTAACAAATATAAAAGAGGAAAACTTAACATATCCTTAA

Upstream 100 bases:

>100_bases
CTATTTACTCTAAGACATGCATATACGGACATTTCGGAAAAAATGAACTAGAATGGGAAAAATTAGATTTCGTAGACATA
ATAAAAAAGGAGTTTAAAAT

Downstream 100 bases:

>100_bases
GAACAGTAAAAATCCATTTACAAAAAACACTATGTCATTTGTAAAATATAAGTAAGATATTTTACAATATGTCCTGCAAT
TTAAATTCAACATACAGACT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNKISSFTIDHTKLKPGIYISRKDIFENLTCTTVDIRMKAPNREPVINNAEMHTIEHIGATLLRNNKVWGDKILYFGPMG
CRTGFYLILLGNYESKDLIDLISWLFHEITNFQGNVTGATEKECGNYQDHNLNMAKYESNRYLTTLTNIKEENLTYP

Sequences:

>Translated_157_residues
MNKISSFTIDHTKLKPGIYISRKDIFENLTCTTVDIRMKAPNREPVINNAEMHTIEHIGATLLRNNKVWGDKILYFGPMG
CRTGFYLILLGNYESKDLIDLISWLFHEITNFQGNVTGATEKECGNYQDHNLNMAKYESNRYLTTLTNIKEENLTYP
>Mature_157_residues
MNKISSFTIDHTKLKPGIYISRKDIFENLTCTTVDIRMKAPNREPVINNAEMHTIEHIGATLLRNNKVWGDKILYFGPMG
CRTGFYLILLGNYESKDLIDLISWLFHEITNFQGNVTGATEKECGNYQDHNLNMAKYESNRYLTTLTNIKEENLTYP

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=141, Percent_Identity=31.2056737588652, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18127; Mature: 18127

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKISSFTIDHTKLKPGIYISRKDIFENLTCTTVDIRMKAPNREPVINNAEMHTIEHIGA
CCCCCCEEEEEEECCCCEEEEHHHHHCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
TLLRNNKVWGDKILYFGPMGCRTGFYLILLGNYESKDLIDLISWLFHEITNFQGNVTGAT
HHHCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCC
EKECGNYQDHNLNMAKYESNRYLTTLTNIKEENLTYP
CHHCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNKISSFTIDHTKLKPGIYISRKDIFENLTCTTVDIRMKAPNREPVINNAEMHTIEHIGA
CCCCCCEEEEEEECCCCEEEEHHHHHCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
TLLRNNKVWGDKILYFGPMGCRTGFYLILLGNYESKDLIDLISWLFHEITNFQGNVTGAT
HHHCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCC
EKECGNYQDHNLNMAKYESNRYLTTLTNIKEENLTYP
CHHCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA