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The map label for this gene is apeA [H]

Identifier: 187918233

GI number: 187918233

Start: 376542

End: 377918

Strand: Direct

Name: apeA [H]

Synonym: BH0366

Alternate gene names: 187918233

Gene position: 376542-377918 (Clockwise)

Preceding gene: 187918232

Following gene: 187918234

Centisome position: 40.83

GC content: 33.12

Gene sequence:

>1377_bases
ATGACAAAACAAAATCCTTGGGTTTCTTTAAACGAAAAAGAGAGAAATAATGTTTTAGAATTTGCTCAAAAATATAAAAA
ATTTTTAAGCACAGTTAAAACCGAACGAGAAGCTACCAACTATGCTATACAAAAGGCAAAGGAAAAAGGTTTCATTAATG
CCTGCGAAAAACAAGAATTCAAAGCTGGAGATAAAATCTTTTACACATGTCGCAATAAAAACATTGCTCTTATATTTATT
GGAAGAGAGCCTATTGAGAATGGAATGAATTTCATTGTATCACATACAGATTCACCAAGACTTGATGCCAAACCATCACC
GATTGCTGAAGAGAATGAATTTACAATGATGAAGACAAATTATTACGGAGGCATTAAAAAATATCAATGGTTATCCCTTC
CTCTATCAATACGAGGAGTAATATTTTTGCAAAACGGAGAAAAAGTAGAGATTAACATCGGTGATGATAACAATGATCCC
GTATTTGTAATTCCCGACATCTTGCCACATCTTGACAGAAAAGTACAAAGAGATAAAAAAGCTGATGACATCATAGAAGG
TGAAAATTTAAAAATCATAATTGGAAGCCTACCTATTGACACTAAAGAAAAAGAAAAAGTAAAATTTGCTACTCTTAAGC
TCATAAAAGAAAAATATAAAATAGAAGAAGAGGATTTCGTTTCAGCAGAAATAGAAATAGTACCAGCAGGAGAAGCAAAA
GATGTCGGATTTGACAGGGCACTAATTGGTGCTTATGGTCAAGATGACAGGGTTTGTGTTTACACTTCACTAGAAGCTAT
ACTTAATCTAGAAGAAACACCAAGCAAAACCGCTGTATGTTTTTTAGTTGACAAAGAAGAAATTGGATCAACTGGATCAA
CTGGACTAAATTCAAGATATCTTGAATATTTCGTATCAGACATAATATTTAAACTTAAAGAAGATAAATATAACAATCTC
CTTGTTCAAAAAGTATTATGGAACTCAAAAAGCATATCTGCTGATGTTTGTGGTGCAATAAATCCCCTATTTAAATCAGT
TCATGATGAACAAAACGCACCTAAATTGGGATATGGAATACCTATAATGAAATACACAGGTCACGGGGGTAAAATCATGG
CTAGTGATTCTGATGCTGAGCTTGTCTCTTATATTAGGAATTTACTAAATAAAAATAACATAGCTTGGCAAGTAGCCACA
CTTGGAAAAGTAGACGAAGGTGGTGGCGGAACTGTTGCAAAATTCTTAGCACATTATGGAATAAGAACAATAGACATGGG
ACCTGGTGTTATTAGTATGCACTCACCATTTGAAATCACTTCTAAATTTGACATATATACTTCTTATATGGCTTATAAAG
CGTTCTTTGAAGGATAA

Upstream 100 bases:

>100_bases
ACACTGCAAAATTAATCCATTGCAGCTGTTTTTCATTATTGCTAAACTGCATTTAAAAAGAATAGAATGTTATAATAAGT
AATCAGGAGGAGAAATTTTA

Downstream 100 bases:

>100_bases
CTAAATGAATAAAGAAACAATAAAAACATCGGAACATATTTTAGAATGCTTTGGGGGCATTGCAAACATTAAACAAGTAA
ACAAAGATTTAACTAGAATA

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTKQNPWVSLNEKERNNVLEFAQKYKKFLSTVKTEREATNYAIQKAKEKGFINACEKQEFKAGDKIFYTCRNKNIALIFI
GREPIENGMNFIVSHTDSPRLDAKPSPIAEENEFTMMKTNYYGGIKKYQWLSLPLSIRGVIFLQNGEKVEINIGDDNNDP
VFVIPDILPHLDRKVQRDKKADDIIEGENLKIIIGSLPIDTKEKEKVKFATLKLIKEKYKIEEEDFVSAEIEIVPAGEAK
DVGFDRALIGAYGQDDRVCVYTSLEAILNLEETPSKTAVCFLVDKEEIGSTGSTGLNSRYLEYFVSDIIFKLKEDKYNNL
LVQKVLWNSKSISADVCGAINPLFKSVHDEQNAPKLGYGIPIMKYTGHGGKIMASDSDAELVSYIRNLLNKNNIAWQVAT
LGKVDEGGGGTVAKFLAHYGIRTIDMGPGVISMHSPFEITSKFDIYTSYMAYKAFFEG

Sequences:

>Translated_458_residues
MTKQNPWVSLNEKERNNVLEFAQKYKKFLSTVKTEREATNYAIQKAKEKGFINACEKQEFKAGDKIFYTCRNKNIALIFI
GREPIENGMNFIVSHTDSPRLDAKPSPIAEENEFTMMKTNYYGGIKKYQWLSLPLSIRGVIFLQNGEKVEINIGDDNNDP
VFVIPDILPHLDRKVQRDKKADDIIEGENLKIIIGSLPIDTKEKEKVKFATLKLIKEKYKIEEEDFVSAEIEIVPAGEAK
DVGFDRALIGAYGQDDRVCVYTSLEAILNLEETPSKTAVCFLVDKEEIGSTGSTGLNSRYLEYFVSDIIFKLKEDKYNNL
LVQKVLWNSKSISADVCGAINPLFKSVHDEQNAPKLGYGIPIMKYTGHGGKIMASDSDAELVSYIRNLLNKNNIAWQVAT
LGKVDEGGGGTVAKFLAHYGIRTIDMGPGVISMHSPFEITSKFDIYTSYMAYKAFFEG
>Mature_457_residues
TKQNPWVSLNEKERNNVLEFAQKYKKFLSTVKTEREATNYAIQKAKEKGFINACEKQEFKAGDKIFYTCRNKNIALIFIG
REPIENGMNFIVSHTDSPRLDAKPSPIAEENEFTMMKTNYYGGIKKYQWLSLPLSIRGVIFLQNGEKVEINIGDDNNDPV
FVIPDILPHLDRKVQRDKKADDIIEGENLKIIIGSLPIDTKEKEKVKFATLKLIKEKYKIEEEDFVSAEIEIVPAGEAKD
VGFDRALIGAYGQDDRVCVYTSLEAILNLEETPSKTAVCFLVDKEEIGSTGSTGLNSRYLEYFVSDIIFKLKEDKYNNLL
VQKVLWNSKSISADVCGAINPLFKSVHDEQNAPKLGYGIPIMKYTGHGGKIMASDSDAELVSYIRNLLNKNNIAWQVATL
GKVDEGGGGTVAKFLAHYGIRTIDMGPGVISMHSPFEITSKFDIYTSYMAYKAFFEG

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=475, Percent_Identity=22.7368421052632, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17552916, Length=461, Percent_Identity=24.295010845987, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321905, Length=476, Percent_Identity=23.9495798319328, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322746, Length=477, Percent_Identity=25.3668763102725, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51553; Mature: 51421

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQNPWVSLNEKERNNVLEFAQKYKKFLSTVKTEREATNYAIQKAKEKGFINACEKQEF
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
KAGDKIFYTCRNKNIALIFIGREPIENGMNFIVSHTDSPRLDAKPSPIAEENEFTMMKTN
CCCCEEEEEECCCCEEEEEEECCCHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEC
YYGGIKKYQWLSLPLSIRGVIFLQNGEKVEINIGDDNNDPVFVIPDILPHLDRKVQRDKK
CCCCCCEEEEEECCEEEEEEEEEECCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHCCC
ADDIIEGENLKIIIGSLPIDTKEKEKVKFATLKLIKEKYKIEEEDFVSAEIEIVPAGEAK
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCC
DVGFDRALIGAYGQDDRVCVYTSLEAILNLEETPSKTAVCFLVDKEEIGSTGSTGLNSRY
CCCCCHHEEECCCCCCCEEEEEEHHHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCCCHHH
LEYFVSDIIFKLKEDKYNNLLVQKVLWNSKSISADVCGAINPLFKSVHDEQNAPKLGYGI
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PIMKYTGHGGKIMASDSDAELVSYIRNLLNKNNIAWQVATLGKVDEGGGGTVAKFLAHYG
EEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
IRTIDMGPGVISMHSPFEITSKFDIYTSYMAYKAFFEG
CEEEECCCCEEEECCCCEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKQNPWVSLNEKERNNVLEFAQKYKKFLSTVKTEREATNYAIQKAKEKGFINACEKQEF
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
KAGDKIFYTCRNKNIALIFIGREPIENGMNFIVSHTDSPRLDAKPSPIAEENEFTMMKTN
CCCCEEEEEECCCCEEEEEEECCCHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEC
YYGGIKKYQWLSLPLSIRGVIFLQNGEKVEINIGDDNNDPVFVIPDILPHLDRKVQRDKK
CCCCCCEEEEEECCEEEEEEEEEECCCEEEEEECCCCCCCEEEECHHHHHHHHHHHHCCC
ADDIIEGENLKIIIGSLPIDTKEKEKVKFATLKLIKEKYKIEEEDFVSAEIEIVPAGEAK
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCC
DVGFDRALIGAYGQDDRVCVYTSLEAILNLEETPSKTAVCFLVDKEEIGSTGSTGLNSRY
CCCCCHHEEECCCCCCCEEEEEEHHHHHCCCCCCCCEEEEEEEEHHHCCCCCCCCCCHHH
LEYFVSDIIFKLKEDKYNNLLVQKVLWNSKSISADVCGAINPLFKSVHDEQNAPKLGYGI
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PIMKYTGHGGKIMASDSDAELVSYIRNLLNKNNIAWQVATLGKVDEGGGGTVAKFLAHYG
EEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
IRTIDMGPGVISMHSPFEITSKFDIYTSYMAYKAFFEG
CEEEECCCCEEEECCCCEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA