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The map label for this gene is gtaB [H]

Identifier: 187918080

GI number: 187918080

Start: 207771

End: 208604

Strand: Direct

Name: gtaB [H]

Synonym: BH0207

Alternate gene names: 187918080

Gene position: 207771-208604 (Clockwise)

Preceding gene: 187918078

Following gene: 187918081

Centisome position: 22.53

GC content: 30.34

Gene sequence:

>834_bases
ATGAAAGGTATTATCTTAGCAGCAGGGTATGGAACAAGATTCTTACCCATTACAAAAACTATTCCAAAGGAAATGCTACC
AATTTTAAACAAACCGTCAATCGATTACATTATTGAAGAATTTACTAGTTCTGGAATCAAAGAAATACTAATAATAACCT
CAAGAAGAAAGGGAGCTTTGGATAATTATTTTGATAGAGAAATTGAACTTGAGACTGAATTTGCTAAAAAATATAGAGAA
GATTTGCTAAAAAAAATTAAACTTAAAGACATTAATATTAGCTTTATAAGGCAAAATGAAATGATGGGCACAGGTCATGC
TTTACTGCAGGTAAAACCCTGGATAGGAACTGAAAGTGTAATAGTTGCATACCCTGATGATTTACATGTTGGATCCCCAC
CCTTAACAGCACAACTAATAGAATTGCATAAAAAAACTGGAAAAAACATATTATCTGTCATTGAAAATCCCAAAGATATC
AACAGATACGGAGTAATAGAATTAAATAAAGACAATATTCATGTCAAAGACATAGTAGAAAAACCAGAAATTGGAAAAGA
ACCAAGCAATAAAGCATCTATTGGAAGATTCTTATATACCCATGAATTTTTCAAATTTTTAGAAGAAGGGTTTAAACTTC
ATCAAAAAGGAGAATATCATCATATTTATGCTTTAAAAAAACTCATGTCTGAGAACAAAGTATTATACAAAGAAATAGAA
GGAGAAAGACTTGATATAGGTGATATTGGGGGTTATTTAGAAGCAATAATCAAAATTGCAAAACGCAATGATCAATTGCT
ACAAATCATCAAAGACTCACTAAGGACTAAATGA

Upstream 100 bases:

>100_bases
TGCACTTACATGCATAAGGACAAATTCTAAATCATTTTTCAAAAAAATTAAATATTTATGATTTAAATTTTGATATAATT
TTATTTAAGAGAGACAAAAA

Downstream 100 bases:

>100_bases
ATATATCAACAAAATGCCAAGAGTTTTATGATGCTCTTAGCATATTAAAAAAATACATACATATAAACATAGAAGAAAAA
ATTTTAAGATACAGCATTTT

Product: UTP--glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPSIDYIIEEFTSSGIKEILIITSRRKGALDNYFDREIELETEFAKKYRE
DLLKKIKLKDINISFIRQNEMMGTGHALLQVKPWIGTESVIVAYPDDLHVGSPPLTAQLIELHKKTGKNILSVIENPKDI
NRYGVIELNKDNIHVKDIVEKPEIGKEPSNKASIGRFLYTHEFFKFLEEGFKLHQKGEYHHIYALKKLMSENKVLYKEIE
GERLDIGDIGGYLEAIIKIAKRNDQLLQIIKDSLRTK

Sequences:

>Translated_277_residues
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPSIDYIIEEFTSSGIKEILIITSRRKGALDNYFDREIELETEFAKKYRE
DLLKKIKLKDINISFIRQNEMMGTGHALLQVKPWIGTESVIVAYPDDLHVGSPPLTAQLIELHKKTGKNILSVIENPKDI
NRYGVIELNKDNIHVKDIVEKPEIGKEPSNKASIGRFLYTHEFFKFLEEGFKLHQKGEYHHIYALKKLMSENKVLYKEIE
GERLDIGDIGGYLEAIIKIAKRNDQLLQIIKDSLRTK
>Mature_277_residues
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPSIDYIIEEFTSSGIKEILIITSRRKGALDNYFDREIELETEFAKKYRE
DLLKKIKLKDINISFIRQNEMMGTGHALLQVKPWIGTESVIVAYPDDLHVGSPPLTAQLIELHKKTGKNILSVIENPKDI
NRYGVIELNKDNIHVKDIVEKPEIGKEPSNKASIGRFLYTHEFFKFLEEGFKLHQKGEYHHIYALKKLMSENKVLYKEIE
GERLDIGDIGGYLEAIIKIAKRNDQLLQIIKDSLRTK

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a mem

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=266, Percent_Identity=23.6842105263158, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788355, Length=282, Percent_Identity=32.6241134751773, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787488, Length=282, Percent_Identity=31.5602836879433, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790224, Length=252, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI133931050, Length=200, Percent_Identity=23.5, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=283, Percent_Identity=25.0883392226148, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 31832; Mature: 31832

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPSIDYIIEEFTSSGIKEILIITSRRKGAL
CCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCC
DNYFDREIELETEFAKKYREDLLKKIKLKDINISFIRQNEMMGTGHALLQVKPWIGTESV
HHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCE
IVAYPDDLHVGSPPLTAQLIELHKKTGKNILSVIENPKDINRYGVIELNKDNIHVKDIVE
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHC
KPEIGKEPSNKASIGRFLYTHEFFKFLEEGFKLHQKGEYHHIYALKKLMSENKVLYKEIE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEHHCC
GERLDIGDIGGYLEAIIKIAKRNDQLLQIIKDSLRTK
CCEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGIILAAGYGTRFLPITKTIPKEMLPILNKPSIDYIIEEFTSSGIKEILIITSRRKGAL
CCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCC
DNYFDREIELETEFAKKYREDLLKKIKLKDINISFIRQNEMMGTGHALLQVKPWIGTESV
HHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCCCE
IVAYPDDLHVGSPPLTAQLIELHKKTGKNILSVIENPKDINRYGVIELNKDNIHVKDIVE
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHC
KPEIGKEPSNKASIGRFLYTHEFFKFLEEGFKLHQKGEYHHIYALKKLMSENKVLYKEIE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEHHCC
GERLDIGDIGGYLEAIIKIAKRNDQLLQIIKDSLRTK
CCEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA