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The map label for this gene is hflC [H]

Identifier: 187918077

GI number: 187918077

Start: 203928

End: 204899

Strand: Direct

Name: hflC [H]

Synonym: BH0204

Alternate gene names: 187918077

Gene position: 203928-204899 (Clockwise)

Preceding gene: 187918076

Following gene: 187918078

Centisome position: 22.11

GC content: 31.07

Gene sequence:

>972_bases
ATGAAATACATACTAAGATTTTTATTCTCTATAGCTAAGATTTTAGCTTTTACATTAACATTTGGATTAGTATCGTTAGC
CATAATGCAACCACTCTATATTTTAAGAGAAAATGAAATTTCAATTACTACAAGACTTGGTAAAATTGAAAGAACTGAAA
ACACGGCAGGACTTAAATATAAAATCCCATTTATTGAAAATGTACAAATATTTCCCAAAAATATACTTAGATGGGATGGA
GAACCTCAAAGAATTCCAACAGGAGGAGAAGAAAAACAATTAATCTGGATAGATACAACTGCTAGGTGGAAAATTGTAGA
TGTTAATCAATTCTATACAGCAATCAAAACAATGAACCGAGCTTCCACAATAATCAATGCAGCTATTGAGCCTGCGGTTA
GAGGTGTTATTGCCAAGTATCCTTTACTTGAAATTATTAGAAGTTCAAATGATCCAATTCAACGTCTATCTGATGGAATT
TTAACACCACAAGACGCTACAGATAATACAACTTACAAGATCACAAAGGGTCGTAAAATAATTGAAAATGAAATAATCGA
AGTTTCCAATCAAAATACAAAAGACAATGGAATTGAAATTGTCGATGTTCTGATTAGAAAAATAGGTTATGATCCAAGTT
TAATTGACTCTGTACATAATAGAATGATTTCAGAAAGGCAACAAGTTGCAGAAGAACAAAGAAGTACAGGAATTGCCGAG
AAAACAGAAATTCTTGGTAGCATTGAGAAAGAAAAGTTAAAGTTATTAAGTGAAGCAAAAGCTGAAGCAGCCAAAATTAA
AGCTGAAGGAGACCATGAGGCTGCAAAAATTTATGCAAATGCCTATAGCAAAAATGTTGAATTTTACAAATTTTGGCAAG
CACTAGAGAGTTACAAAGCAACTCTTAAAGACAAACGAAAAATATTCTCAACAGATATGGATTTCTTTAAATACTTACAT
AATAAAAAATAA

Upstream 100 bases:

>100_bases
TATAACGAAACAATGAGGGAAATTCTTGAAAGCAGAGACAACATTGAAATAATTGACAAAAACTTAAATAATTTCCTTCC
ATTTAAGGAGGTTAAGTAAG

Downstream 100 bases:

>100_bases
AAAAATTAATATGAAAAATTCATTTAAAACAGAATCTTAAATGAATAAATATTTAAAGAACAACGCATTAAAATGAGCAA
AAAGTAAATTACAAAGAATG

Product: protease activity modulator HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKYILRFLFSIAKILAFTLTFGLVSLAIMQPLYILRENEISITTRLGKIERTENTAGLKYKIPFIENVQIFPKNILRWDG
EPQRIPTGGEEKQLIWIDTTARWKIVDVNQFYTAIKTMNRASTIINAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSDGI
LTPQDATDNTTYKITKGRKIIENEIIEVSNQNTKDNGIEIVDVLIRKIGYDPSLIDSVHNRMISERQQVAEEQRSTGIAE
KTEILGSIEKEKLKLLSEAKAEAAKIKAEGDHEAAKIYANAYSKNVEFYKFWQALESYKATLKDKRKIFSTDMDFFKYLH
NKK

Sequences:

>Translated_323_residues
MKYILRFLFSIAKILAFTLTFGLVSLAIMQPLYILRENEISITTRLGKIERTENTAGLKYKIPFIENVQIFPKNILRWDG
EPQRIPTGGEEKQLIWIDTTARWKIVDVNQFYTAIKTMNRASTIINAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSDGI
LTPQDATDNTTYKITKGRKIIENEIIEVSNQNTKDNGIEIVDVLIRKIGYDPSLIDSVHNRMISERQQVAEEQRSTGIAE
KTEILGSIEKEKLKLLSEAKAEAAKIKAEGDHEAAKIYANAYSKNVEFYKFWQALESYKATLKDKRKIFSTDMDFFKYLH
NKK
>Mature_323_residues
MKYILRFLFSIAKILAFTLTFGLVSLAIMQPLYILRENEISITTRLGKIERTENTAGLKYKIPFIENVQIFPKNILRWDG
EPQRIPTGGEEKQLIWIDTTARWKIVDVNQFYTAIKTMNRASTIINAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSDGI
LTPQDATDNTTYKITKGRKIIENEIIEVSNQNTKDNGIEIVDVLIRKIGYDPSLIDSVHNRMISERQQVAEEQRSTGIAE
KTEILGSIEKEKLKLLSEAKAEAAKIKAEGDHEAAKIYANAYSKNVEFYKFWQALESYKATLKDKRKIFSTDMDFFKYLH
NKK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=316, Percent_Identity=28.4810126582279, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 37024; Mature: 37024

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYILRFLFSIAKILAFTLTFGLVSLAIMQPLYILRENEISITTRLGKIERTENTAGLKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCEEE
KIPFIENVQIFPKNILRWDGEPQRIPTGGEEKQLIWIDTTARWKIVDVNQFYTAIKTMNR
ECCCCCCCEECCHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHH
ASTIINAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSDGILTPQDATDNTTYKITKGRKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCHH
IENEIIEVSNQNTKDNGIEIVDVLIRKIGYDPSLIDSVHNRMISERQQVAEEQRSTGIAE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KTEILGSIEKEKLKLLSEAKAEAAKIKAEGDHEAAKIYANAYSKNVEFYKFWQALESYKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TLKDKRKIFSTDMDFFKYLHNKK
HHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MKYILRFLFSIAKILAFTLTFGLVSLAIMQPLYILRENEISITTRLGKIERTENTAGLKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCEEE
KIPFIENVQIFPKNILRWDGEPQRIPTGGEEKQLIWIDTTARWKIVDVNQFYTAIKTMNR
ECCCCCCCEECCHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHHHHHH
ASTIINAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSDGILTPQDATDNTTYKITKGRKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCHH
IENEIIEVSNQNTKDNGIEIVDVLIRKIGYDPSLIDSVHNRMISERQQVAEEQRSTGIAE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KTEILGSIEKEKLKLLSEAKAEAAKIKAEGDHEAAKIYANAYSKNVEFYKFWQALESYKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TLKDKRKIFSTDMDFFKYLHNKK
HHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]