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The map label for this gene is hflK [H]

Identifier: 187918076

GI number: 187918076

Start: 202994

End: 203926

Strand: Direct

Name: hflK [H]

Synonym: BH0203

Alternate gene names: 187918076

Gene position: 202994-203926 (Clockwise)

Preceding gene: 187918075

Following gene: 187918077

Centisome position: 22.01

GC content: 28.62

Gene sequence:

>933_bases
ATGTTAAATAACATCTTAAAATTTTTCAATAAAACATATGAATACATGATAATTTTAATTATACTAGTAATTATATTAAT
AATAACAATTGCAAATATTTTTGTGGTTGGTCCATCTGAGGAAGCCATTGTCCTGCGTCTTGGCAAGTTAAATAGAATAC
TTGAACCGGGAATACATATAAAAATTCCATTAATTGAAGAAAAAGCAATTGTACCGGTAAAGATCGTACAAGAAGTTAAA
TTTGGTTTTAATGCAAACAATAATATAGAAGCTAATTTGGATGAAAATGAAGGAATAATTATTACTGGTGACTTGAATAT
AATTAAAGTTGAATGGCTAGTACAATATAAAATCAGCGATCCATATGCTTTCATGTTTAAAGTAGAAGATCCAGAAAAAA
CCATAATAGATATTGCAAAATCATCAATGAACAGATTAATTGGGGACAATACTATTTTTGAGATAATTAATGATAATAGG
GTTGGTGTTACAGAAGGAGTAAAAGCCTCTATGAATGAAATTATAAAAACATATGATTTAGGAATTGATATTGTGCAAGT
ACAAATCAGAAATGCTATGCCGCCAAAGGGAAAAGTTTATGAGGCATTTGAAGATGTTAATATTGCAATCCAAGATAAAA
ATAAATTTGTTAATGAGGGAAGGAAAGAATTTAATCAAATTATCCCAAAAATTAGAGGAGAAGCACTTAAAGTGCTAGAA
GAAGCTAAGGGATATAAAGAAAGCAGAATAAATAATGCACTAGCTGATACTGCTATCTTTAATGCAATTCTAAATGCATA
CATCCAAGATCCAGAAATTACAATAGAGAGAATCTATAACGAAACAATGAGGGAAATTCTTGAAAGCAGAGACAACATTG
AAATAATTGACAAAAACTTAAATAATTTCCTTCCATTTAAGGAGGTTAAGTAA

Upstream 100 bases:

>100_bases
AACTTAAACACAAAATACGCCCTAAGAAAAATTAAAACATAAAGGACTTAAAAATAAAAATATATGATTTTTTGGAAATA
AATAATAAAAAGGAGGAAAA

Downstream 100 bases:

>100_bases
GATGAAATACATACTAAGATTTTTATTCTCTATAGCTAAGATTTTAGCTTTTACATTAACATTTGGATTAGTATCGTTAG
CCATAATGCAACCACTCTAT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MLNNILKFFNKTYEYMIILIILVIILIITIANIFVVGPSEEAIVLRLGKLNRILEPGIHIKIPLIEEKAIVPVKIVQEVK
FGFNANNNIEANLDENEGIIITGDLNIIKVEWLVQYKISDPYAFMFKVEDPEKTIIDIAKSSMNRLIGDNTIFEIINDNR
VGVTEGVKASMNEIIKTYDLGIDIVQVQIRNAMPPKGKVYEAFEDVNIAIQDKNKFVNEGRKEFNQIIPKIRGEALKVLE
EAKGYKESRINNALADTAIFNAILNAYIQDPEITIERIYNETMREILESRDNIEIIDKNLNNFLPFKEVK

Sequences:

>Translated_310_residues
MLNNILKFFNKTYEYMIILIILVIILIITIANIFVVGPSEEAIVLRLGKLNRILEPGIHIKIPLIEEKAIVPVKIVQEVK
FGFNANNNIEANLDENEGIIITGDLNIIKVEWLVQYKISDPYAFMFKVEDPEKTIIDIAKSSMNRLIGDNTIFEIINDNR
VGVTEGVKASMNEIIKTYDLGIDIVQVQIRNAMPPKGKVYEAFEDVNIAIQDKNKFVNEGRKEFNQIIPKIRGEALKVLE
EAKGYKESRINNALADTAIFNAILNAYIQDPEITIERIYNETMREILESRDNIEIIDKNLNNFLPFKEVK
>Mature_310_residues
MLNNILKFFNKTYEYMIILIILVIILIITIANIFVVGPSEEAIVLRLGKLNRILEPGIHIKIPLIEEKAIVPVKIVQEVK
FGFNANNNIEANLDENEGIIITGDLNIIKVEWLVQYKISDPYAFMFKVEDPEKTIIDIAKSSMNRLIGDNTIFEIINDNR
VGVTEGVKASMNEIIKTYDLGIDIVQVQIRNAMPPKGKVYEAFEDVNIAIQDKNKFVNEGRKEFNQIIPKIRGEALKVLE
EAKGYKESRINNALADTAIFNAILNAYIQDPEITIERIYNETMREILESRDNIEIIDKNLNNFLPFKEVK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=271, Percent_Identity=29.1512915129151, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 35452; Mature: 35452

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNILKFFNKTYEYMIILIILVIILIITIANIFVVGPSEEAIVLRLGKLNRILEPGIHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEHHHHHHHCCCCEE
KIPLIEEKAIVPVKIVQEVKFGFNANNNIEANLDENEGIIITGDLNIIKVEWLVQYKISD
EEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCEEEEEEEEEEEEECC
PYAFMFKVEDPEKTIIDIAKSSMNRLIGDNTIFEIINDNRVGVTEGVKASMNEIIKTYDL
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHC
GIDIVQVQIRNAMPPKGKVYEAFEDVNIAIQDKNKFVNEGRKEFNQIIPKIRGEALKVLE
CCEEEEEEECCCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKGYKESRINNALADTAIFNAILNAYIQDPEITIERIYNETMREILESRDNIEIIDKNL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCH
NNFLPFKEVK
HHCCCCCCCC
>Mature Secondary Structure
MLNNILKFFNKTYEYMIILIILVIILIITIANIFVVGPSEEAIVLRLGKLNRILEPGIHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEHHHHHHHCCCCEE
KIPLIEEKAIVPVKIVQEVKFGFNANNNIEANLDENEGIIITGDLNIIKVEWLVQYKISD
EEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCCEEEEEEEEEEEEECC
PYAFMFKVEDPEKTIIDIAKSSMNRLIGDNTIFEIINDNRVGVTEGVKASMNEIIKTYDL
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHC
GIDIVQVQIRNAMPPKGKVYEAFEDVNIAIQDKNKFVNEGRKEFNQIIPKIRGEALKVLE
CCEEEEEEECCCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAKGYKESRINNALADTAIFNAILNAYIQDPEITIERIYNETMREILESRDNIEIIDKNL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCH
NNFLPFKEVK
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]