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The map label for this gene is yegW

Identifier: 187733544

GI number: 187733544

Start: 1028843

End: 1029589

Strand: Direct

Name: yegW

Synonym: SbBS512_E1138

Alternate gene names: 187733544

Gene position: 1028843-1029589 (Clockwise)

Preceding gene: 187730678

Following gene: 187731521

Centisome position: 22.29

GC content: 51.14

Gene sequence:

>747_bases
ATGGAACAAGCGCATACCCAGCTGATTGCCCAACTGAACGAACGTATTTTAGCGGCGGATAACACGCCGCTTTATATTAA
GTTTGCCGAAACGGTAAAAAATGCCGTGCGCAGCGGGGTGCTGGAGCATGGCAATATTTTGCCCGGTGAGCGTGATTTAA
GTCAGTTAACCGGCGTTTCGCGCATTACGGTGCGCAAGGCGATGCAGGCGCTGGAAGAAGAGGGTGTGGTGACGCGTTCG
CGTGGTTACGGCACGCAGATCAACAACATCTTCGAATACTCGTTGAAAGAAGCGCGAGGTTTTTCTCAGCAGGTGGTATT
GCGCGGGAAAAAGCCCGATACGCTATGGGTTAACAAGCGTGTCGTGAAATGTCCCGAAGAAGTCGCGCAGCAGCTGGCGG
TCGAAGCAGGAAGTGATGTCTTTTTGCTTAAGCGTATTCGCTATGTCGATGAAGAAGCGGTATCGATTGAGGAATCGTGG
GTTCCGGCGCATTTAATTCATGATGTTGATGCCATCGGGATTTCACTTTATGACTATTTCCGCAGCCAGCACATTTACCC
ACAACGTACGCGTTCCCGCGTTAGCGCCCGGATGCCGGATGCCGAGTTTCAGTCACATATTCAGTTAGATAGCAAAATAC
CGGTGCTGGTGATCAAGCAAGTGGCGCTTGACCAACAGCAACGGCCTATTGAGTACAGCATTAGCCACTGTCGCAGCGAT
CTATACGTTTTTGTGTGCGAGGAGTAG

Upstream 100 bases:

>100_bases
GGTGGAGGAGTTGCAGGGGTTCGTTGATGGGATTAAAGAAACGCCTTAAATAAGAAGCAGTGATATACTCCCACCAGACT
CCCTGGCAGGAAAAAGACAA

Downstream 100 bases:

>100_bases
TTCCTCGCGCGTTGGCGCACAATCACCGCCCCGATGCCCGACAACCCACGACGCCACTGCATTGCCCAGTAATACGGCAT
CCGCCAGTGGCAGACCAGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRS
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVIKQVALDQQQRPIEYSISHCRSD
LYVFVCEE

Sequences:

>Translated_248_residues
MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRS
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVIKQVALDQQQRPIEYSISHCRSD
LYVFVCEE
>Mature_248_residues
MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRS
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVIKQVALDQQQRPIEYSISHCRSD
LYVFVCEE

Specific function: Unknown

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788418, Length=248, Percent_Identity=100, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI87082252, Length=226, Percent_Identity=29.2035398230088, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790540, Length=214, Percent_Identity=28.0373831775701, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=25.4310344827586, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790118, Length=148, Percent_Identity=25, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YEGW_ECO57 (P0ACM7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85837
- PIR:   H90991
- RefSeq:   NP_288603.1
- RefSeq:   NP_310931.1
- ProteinModelPortal:   P0ACM7
- SMR:   P0ACM7
- EnsemblBacteria:   EBESCT00000027111
- EnsemblBacteria:   EBESCT00000056114
- GeneID:   916607
- GeneID:   956824
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3264
- KEGG:   ecs:ECs2904
- GeneTree:   EBGT00050000008760
- HOGENOM:   HBG417251
- OMA:   SIDESWV
- ProtClustDB:   CLSK880289
- BioCyc:   ECOL83334:ECS2904-MONOMER
- GO:   GO:0005622
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00035
- SMART:   SM00345
- SMART:   SM00866

Pfam domain/function: PF00392 GntR; PF07702 UTRA

EC number: NA

Molecular weight: Translated: 28278; Mature: 28278

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHGNILPGERDLSQLTGVS
CCHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHCHHHCCCCCCCCHHHHHHHCCH
RITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKR
HHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCEEEECCH
VVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESWVPAHLIHDVDAIGISLYDYF
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVIKQVALDQQQRPIEYSISHCRSD
HHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCC
LYVFVCEE
EEEEEECC
>Mature Secondary Structure
MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHGNILPGERDLSQLTGVS
CCHHHHHHHHHHHHHEEECCCCEEEEEEHHHHHHHHHHCHHHCCCCCCCCHHHHHHHCCH
RITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKR
HHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCHHEEEECCCCCEEEECCH
VVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESWVPAHLIHDVDAIGISLYDYF
HHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVIKQVALDQQQRPIEYSISHCRSD
HHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCC
LYVFVCEE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796