Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 187736482

GI number: 187736482

Start: 2433034

End: 2434875

Strand: Direct

Name: htpG [H]

Synonym: Amuc_2002

Alternate gene names: 187736482

Gene position: 2433034-2434875 (Clockwise)

Preceding gene: 187736476

Following gene: 187736483

Centisome position: 91.33

GC content: 58.52

Gene sequence:

>1842_bases
ATGAATACAGAAACACATCAATTTCAGGCGGAAGTCCGGCAGCTGCTGGACATTGTCATCAACGCCCTTTACAGCGACCG
TGAAATCTTTGTCCGCGAACTTGTCTCCAACGCTTCCGACGCCCTGGAAAAACTGCGCCTGAAGCAGCTGACGGACTCCA
ATATTTACCAGCCGGACAAGCCCCTGGAAATCACTGTAGCCACGGATAAGGAAAACAAAACCATCACCATCGCGGATACC
GGCATCGGGATGACGGAAGCGGACCTGGTGGAAAACCTGGGAACCATCGCCCACTCCGGCACCAAAAAATTCATGGAAGC
CCTTAAGCAGAAGCAGGAAGGCGGAGCGGACCTGATCGGTCAGTTCGGCGTGGGCTTCTACAGCTCTTTCATGGTGGCGG
ACCGCGTGGAAGTGTTCACCCGCTCCTATGAACCGGAAGCCGCCTCCCTGCGCTGGTCTTCCGACGGACGGGAAGGCTAC
AGCATCGAAACGCTGGCGGAACCGCTGGACCGGGGCACCCGCATCGTCATCCGCCTGAAAGACGAATATGAAGAATTTTC
CCAGGAATACCGCGTCAAGGAACTCCTGCGCCGCTACTCCAACTTCGTGGGGTTCCCCCTCAACTTCAACGGAGAACACA
TCAACACCGTCCAGGCCATCTGGTCCAAGTCCAAATCCGACGTGAAGCCGGAGGAATATGACGAGTTTTACCAGTTCATC
TCCCATACGGATGAAAAGCCCCTGTCCTACATGCACTTCAGCGCGGACGCCCCTATTGCCCTGAATGCCCTGCTTTTCAT
CCCCAGGCGCAATCCGGAAATGTTCGGATTCGGCCGCGTGGACGCCAACGTGGCCCTGTACTGCAAGCGCGTGCTGATTG
ACGCCAAGCCGGAAGGCCTGCTGCCGGAATGGCTCCGCTTCCTGAACGGCGTGGTGGACAGCGAAGACCTGCCCCTGAAC
ATTTCCCGCGAAATGCTTCAGGACAATTCCCTGGTACGCAAAATCAGCGACATCATCACCAGGCGCTTCATCAAGCATCT
GGAAAAACTGGCGAAGGACGACAAGGAAACCTACAGGGAATTCTACGCGCAATTCTCCCGCTACCTGAAAGAAGGCGTCG
TCACCTCCTGGCCGAACAAGGAATCCCTGGGCAAGCTGCTCCGTTTTGAATCCACGTCCACGGAACCGGGGGAAACGACC
TCATTTGAGGAATACCTTACCCGCATGAAGGAAGGGCAGACGGCCATTTACGCGCTTACCGGCCCTTCCCGCTCCCATCT
GGAAAACAGCCCGTACCTGGAAGCCTTCAAGGCCCGCGGCTATGAAGTGGCCTTCTTCACGGACCACGGGGACGAATTCG
TGCTGGACTCCCTGTCCAGCGTGGACGGCAAGCCCGTCACGATGATCGACCGCGCCGACGTGGAACTCCCCGCCCTGGAA
GAGGAACAGAAGGACGCCCTGCCCCAGGAGGAAGCCGCGGCCCTGGAAGAATGGCTGAAAGGACTGTACCCGGACAAATT
CTCCAAAGTCACCCTGGGCAAGCGCCTGGTCAGCGGAGCCGCCGTAGCCCTGCAAAGCGGCAATGACATGGGGCCGGAAA
TGAGGGCGTACATGAAAGCCATGGGGCAGGAAGTGCCGGAAAGCCACCCGCAGCTGGAACTGAACCCCTCCAACCCTCTG
GTGAAAAAGCTTTCCGCCCTGCGGACGGAAAACCCGGAACTGGCGCAAATGGTGGCGGACCAGATCGCGAATACCGCCCT
GCTCCGCGCCGGCATGCTGGACGATCCCGCCGTGCTGGCCCAGTCCTCCCAGGCCCTGATGGAACAGCTCCTGCTGAAGT
AG

Upstream 100 bases:

>100_bases
AGCCCCTTTGTGTGACATGGAACGCTCAGGCCCAGGGAAAAAAACTGTCCATCCCCCTTGACGGGGGCCGTATAATGACG
CTCGCAAAACATTTTTCCAT

Downstream 100 bases:

>100_bases
GGGCCCCGGAAGAAACAGCTTCCTTCCCCAACGCCAACGCCGCTCCCTGCCCTCCCCGCCGGGGGCGGCTTTTTCATTTC
TCTTCCCGCCATGAACTCGT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MNTETHQFQAEVRQLLDIVINALYSDREIFVRELVSNASDALEKLRLKQLTDSNIYQPDKPLEITVATDKENKTITIADT
GIGMTEADLVENLGTIAHSGTKKFMEALKQKQEGGADLIGQFGVGFYSSFMVADRVEVFTRSYEPEAASLRWSSDGREGY
SIETLAEPLDRGTRIVIRLKDEYEEFSQEYRVKELLRRYSNFVGFPLNFNGEHINTVQAIWSKSKSDVKPEEYDEFYQFI
SHTDEKPLSYMHFSADAPIALNALLFIPRRNPEMFGFGRVDANVALYCKRVLIDAKPEGLLPEWLRFLNGVVDSEDLPLN
ISREMLQDNSLVRKISDIITRRFIKHLEKLAKDDKETYREFYAQFSRYLKEGVVTSWPNKESLGKLLRFESTSTEPGETT
SFEEYLTRMKEGQTAIYALTGPSRSHLENSPYLEAFKARGYEVAFFTDHGDEFVLDSLSSVDGKPVTMIDRADVELPALE
EEQKDALPQEEAAALEEWLKGLYPDKFSKVTLGKRLVSGAAVALQSGNDMGPEMRAYMKAMGQEVPESHPQLELNPSNPL
VKKLSALRTENPELAQMVADQIANTALLRAGMLDDPAVLAQSSQALMEQLLLK

Sequences:

>Translated_613_residues
MNTETHQFQAEVRQLLDIVINALYSDREIFVRELVSNASDALEKLRLKQLTDSNIYQPDKPLEITVATDKENKTITIADT
GIGMTEADLVENLGTIAHSGTKKFMEALKQKQEGGADLIGQFGVGFYSSFMVADRVEVFTRSYEPEAASLRWSSDGREGY
SIETLAEPLDRGTRIVIRLKDEYEEFSQEYRVKELLRRYSNFVGFPLNFNGEHINTVQAIWSKSKSDVKPEEYDEFYQFI
SHTDEKPLSYMHFSADAPIALNALLFIPRRNPEMFGFGRVDANVALYCKRVLIDAKPEGLLPEWLRFLNGVVDSEDLPLN
ISREMLQDNSLVRKISDIITRRFIKHLEKLAKDDKETYREFYAQFSRYLKEGVVTSWPNKESLGKLLRFESTSTEPGETT
SFEEYLTRMKEGQTAIYALTGPSRSHLENSPYLEAFKARGYEVAFFTDHGDEFVLDSLSSVDGKPVTMIDRADVELPALE
EEQKDALPQEEAAALEEWLKGLYPDKFSKVTLGKRLVSGAAVALQSGNDMGPEMRAYMKAMGQEVPESHPQLELNPSNPL
VKKLSALRTENPELAQMVADQIANTALLRAGMLDDPAVLAQSSQALMEQLLLK
>Mature_613_residues
MNTETHQFQAEVRQLLDIVINALYSDREIFVRELVSNASDALEKLRLKQLTDSNIYQPDKPLEITVATDKENKTITIADT
GIGMTEADLVENLGTIAHSGTKKFMEALKQKQEGGADLIGQFGVGFYSSFMVADRVEVFTRSYEPEAASLRWSSDGREGY
SIETLAEPLDRGTRIVIRLKDEYEEFSQEYRVKELLRRYSNFVGFPLNFNGEHINTVQAIWSKSKSDVKPEEYDEFYQFI
SHTDEKPLSYMHFSADAPIALNALLFIPRRNPEMFGFGRVDANVALYCKRVLIDAKPEGLLPEWLRFLNGVVDSEDLPLN
ISREMLQDNSLVRKISDIITRRFIKHLEKLAKDDKETYREFYAQFSRYLKEGVVTSWPNKESLGKLLRFESTSTEPGETT
SFEEYLTRMKEGQTAIYALTGPSRSHLENSPYLEAFKARGYEVAFFTDHGDEFVLDSLSSVDGKPVTMIDRADVELPALE
EEQKDALPQEEAAALEEWLKGLYPDKFSKVTLGKRLVSGAAVALQSGNDMGPEMRAYMKAMGQEVPESHPQLELNPSNPL
VKKLSALRTENPELAQMVADQIANTALLRAGMLDDPAVLAQSSQALMEQLLLK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=625, Percent_Identity=41.44, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI4507677, Length=668, Percent_Identity=33.9820359281437, Blast_Score=359, Evalue=4e-99,
Organism=Homo sapiens, GI20149594, Length=398, Percent_Identity=37.1859296482412, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI154146191, Length=402, Percent_Identity=33.8308457711443, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI153792590, Length=402, Percent_Identity=34.5771144278607, Blast_Score=210, Evalue=3e-54,
Organism=Escherichia coli, GI1786679, Length=628, Percent_Identity=38.5350318471338, Blast_Score=443, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17559162, Length=660, Percent_Identity=36.8181818181818, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI115535205, Length=636, Percent_Identity=38.8364779874214, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17542208, Length=676, Percent_Identity=34.6153846153846, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI115535167, Length=413, Percent_Identity=44.5520581113801, Blast_Score=327, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=36.4303178484108, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6323840, Length=409, Percent_Identity=35.9413202933985, Blast_Score=233, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24586016, Length=633, Percent_Identity=42.4960505529226, Blast_Score=486, Evalue=1e-137,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=34.8017621145374, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI17647529, Length=404, Percent_Identity=36.6336633663366, Blast_Score=241, Evalue=1e-63,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 69333; Mature: 69333

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTETHQFQAEVRQLLDIVINALYSDREIFVRELVSNASDALEKLRLKQLTDSNIYQPDK
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PLEITVATDKENKTITIADTGIGMTEADLVENLGTIAHSGTKKFMEALKQKQEGGADLIG
CEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
QFGVGFYSSFMVADRVEVFTRSYEPEAASLRWSSDGREGYSIETLAEPLDRGTRIVIRLK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEEEH
DEYEEFSQEYRVKELLRRYSNFVGFPLNFNGEHINTVQAIWSKSKSDVKPEEYDEFYQFI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SHTDEKPLSYMHFSADAPIALNALLFIPRRNPEMFGFGRVDANVALYCKRVLIDAKPEGL
HCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCEECCCCCCHHHHHHHHHHHCCCCCCC
LPEWLRFLNGVVDSEDLPLNISREMLQDNSLVRKISDIITRRFIKHLEKLAKDDKETYRE
CHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
FYAQFSRYLKEGVVTSWPNKESLGKLLRFESTSTEPGETTSFEEYLTRMKEGQTAIYALT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEE
GPSRSHLENSPYLEAFKARGYEVAFFTDHGDEFVLDSLSSVDGKPVTMIDRADVELPALE
CCCHHHCCCCCHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCC
EEQKDALPQEEAAALEEWLKGLYPDKFSKVTLGKRLVSGAAVALQSGNDMGPEMRAYMKA
CHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
MGQEVPESHPQLELNPSNPLVKKLSALRTENPELAQMVADQIANTALLRAGMLDDPAVLA
HHHHCCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QSSQALMEQLLLK
HHHHHHHHHHHCC
>Mature Secondary Structure
MNTETHQFQAEVRQLLDIVINALYSDREIFVRELVSNASDALEKLRLKQLTDSNIYQPDK
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PLEITVATDKENKTITIADTGIGMTEADLVENLGTIAHSGTKKFMEALKQKQEGGADLIG
CEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
QFGVGFYSSFMVADRVEVFTRSYEPEAASLRWSSDGREGYSIETLAEPLDRGTRIVIRLK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEEEH
DEYEEFSQEYRVKELLRRYSNFVGFPLNFNGEHINTVQAIWSKSKSDVKPEEYDEFYQFI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SHTDEKPLSYMHFSADAPIALNALLFIPRRNPEMFGFGRVDANVALYCKRVLIDAKPEGL
HCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCEECCCCCCHHHHHHHHHHHCCCCCCC
LPEWLRFLNGVVDSEDLPLNISREMLQDNSLVRKISDIITRRFIKHLEKLAKDDKETYRE
CHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
FYAQFSRYLKEGVVTSWPNKESLGKLLRFESTSTEPGETTSFEEYLTRMKEGQTAIYALT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEE
GPSRSHLENSPYLEAFKARGYEVAFFTDHGDEFVLDSLSSVDGKPVTMIDRADVELPALE
CCCHHHCCCCCHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCC
EEQKDALPQEEAAALEEWLKGLYPDKFSKVTLGKRLVSGAAVALQSGNDMGPEMRAYMKA
CHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHH
MGQEVPESHPQLELNPSNPLVKKLSALRTENPELAQMVADQIANTALLRAGMLDDPAVLA
HHHHCCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QSSQALMEQLLLK
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA