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The map label for this gene is aat

Identifier: 187736455

GI number: 187736455

Start: 2395373

End: 2395954

Strand: Direct

Name: aat

Synonym: Amuc_1973

Alternate gene names: 187736455

Gene position: 2395373-2395954 (Clockwise)

Preceding gene: 187736454

Following gene: 187736465

Centisome position: 89.91

GC content: 56.53

Gene sequence:

>582_bases
ATGAATGACAGATTGACGCCGGAACTTGTCCTCTCCGCCTATTGCCAGGGGTGTTTTCCCATGGCGGACCCGGAAACGGG
AGAAATCTCCTTTTACGAACCGGACCCGCGCGCCCTGATTCCGCTGGACGACCGCTTCCACATCCCCCACGGCCTCAAAC
GGGCTTTGAATAAAAAACCCTTTGAACTCCGGATGGATACCGCTTTTCCGGAGGTGGTCCATGCCTGCGCCCGGACGGAC
CAGCCGGAAGAACAATGGATAGACGGACAGATTGAAGAAGCATACGGCAAGCTTCACGAGATGGGCTTCGCCCACAGTGT
GGAATGCTGGGACGAGGAAGGGCTGCAGGGAGGACTGTACGGAGTAGCCCTGGGGAAGGCTTTTTTCGGGGAAAGCATGT
TCCACCGGAAAACGGACGCCAGCAAGATCGCCCTGGTGGCTCTGGTGCAATACCTACGGGCGCATCGGTTCCTTTTTCTG
GATACCCAGTGGACTACGCCGCATCTGCTGAAATTCGGAACCTATGAAGTGCCGGCCAAGGAATACCGGAAGCTTCTGAA
GAGGGCACTGGAGGAACAATAA

Upstream 100 bases:

>100_bases
AATTCGTGCCGTTGGACAAAATCCACGGGCTGCCCATGGCCTCACCGGACCGCAAGGCACTGAACTCCCCCACCCTCGGC
AAACTGCTGGACCATATCAG

Downstream 100 bases:

>100_bases
ACTATATTTTACTGTCCGGTGTAAACGGTCATGAGATTGATTCCCAATTATGGGAGATCCGACAGCGCACCGGATTTCAT
AACCTGCTGATGATTTTTCT

Product: leucyl/phenylalanyl-tRNA/protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MNDRLTPELVLSAYCQGCFPMADPETGEISFYEPDPRALIPLDDRFHIPHGLKRALNKKPFELRMDTAFPEVVHACARTD
QPEEQWIDGQIEEAYGKLHEMGFAHSVECWDEEGLQGGLYGVALGKAFFGESMFHRKTDASKIALVALVQYLRAHRFLFL
DTQWTTPHLLKFGTYEVPAKEYRKLLKRALEEQ

Sequences:

>Translated_193_residues
MNDRLTPELVLSAYCQGCFPMADPETGEISFYEPDPRALIPLDDRFHIPHGLKRALNKKPFELRMDTAFPEVVHACARTD
QPEEQWIDGQIEEAYGKLHEMGFAHSVECWDEEGLQGGLYGVALGKAFFGESMFHRKTDASKIALVALVQYLRAHRFLFL
DTQWTTPHLLKFGTYEVPAKEYRKLLKRALEEQ
>Mature_193_residues
MNDRLTPELVLSAYCQGCFPMADPETGEISFYEPDPRALIPLDDRFHIPHGLKRALNKKPFELRMDTAFPEVVHACARTD
QPEEQWIDGQIEEAYGKLHEMGFAHSVECWDEEGLQGGLYGVALGKAFFGESMFHRKTDASKIALVALVQYLRAHRFLFL
DTQWTTPHLLKFGTYEVPAKEYRKLLKRALEEQ

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=184, Percent_Identity=39.1304347826087, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_AKKM8 (B2UNS0)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001878567.1
- ProteinModelPortal:   B2UNS0
- SMR:   B2UNS0
- GeneID:   6274891
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1973
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 22174; Mature: 22174

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRLTPELVLSAYCQGCFPMADPETGEISFYEPDPRALIPLDDRFHIPHGLKRALNKKP
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHCCCC
FELRMDTAFPEVVHACARTDQPEEQWIDGQIEEAYGKLHEMGFAHSVECWDEEGLQGGLY
CEEEECHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
GVALGKAFFGESMFHRKTDASKIALVALVQYLRAHRFLFLDTQWTTPHLLKFGTYEVPAK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHCCCCCCCHH
EYRKLLKRALEEQ
HHHHHHHHHHHCC
>Mature Secondary Structure
MNDRLTPELVLSAYCQGCFPMADPETGEISFYEPDPRALIPLDDRFHIPHGLKRALNKKP
CCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHCCCC
FELRMDTAFPEVVHACARTDQPEEQWIDGQIEEAYGKLHEMGFAHSVECWDEEGLQGGLY
CEEEECHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
GVALGKAFFGESMFHRKTDASKIALVALVQYLRAHRFLFLDTQWTTPHLLKFGTYEVPAK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHCCCCCCCHH
EYRKLLKRALEEQ
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA