| Definition | Akkermansia muciniphila ATCC BAA-835, complete genome. |
|---|---|
| Accession | NC_010655 |
| Length | 2,664,102 |
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The map label for this gene is metH [H]
Identifier: 187736443
GI number: 187736443
Start: 2377647
End: 2381408
Strand: Direct
Name: metH [H]
Synonym: Amuc_1961
Alternate gene names: 187736443
Gene position: 2377647-2381408 (Clockwise)
Preceding gene: 187736442
Following gene: 187736444
Centisome position: 89.25
GC content: 59.36
Gene sequence:
>3762_bases ATGAGCAGAGCATCCAGAACAGAACGCCTTGATTACCTGAAAGACCAGTTACGTAAAAGGGTTGTCATCCTGGATGGCGC CATGGGCACCAATATCCAAAAATTCAGGCTGGGAGAGGGAGATTACCGCGGAGAACGTTTTGCGGATGCGGAATGCTATC CCAACGATTTAAAGAATAATAACGACCTTCTGGTTCTGACCAGGCCGGATATCATTCTTGATATTCACCGCCGCTTTCTT GACACGGGACGGACGGATATTCTGGAAACCTGCACATTCGGAGCTACCAGCATCGGCCAGCATGATTATTTCTGGCACCG TCCGGAGGAAGGCAGCCACAAGGACCAGCAGTATTTCCAGGAAGTGGTGGACGCCCCCGAATTGAAGGCCCTTGTCCGGG AATTGAATTTGGCGGCAGCCGCACTGGCCCGGCAGGCATGCGACGAAGCGGAAGCTGCAGACGGCAAGCCCCGCCTGGTG GCCGGGTCCATCGGCCCCATGCCCGTCACCTGTTCCCTGTCCCCCGACGTGAATGATCCCGGTTTCCGCGCCGTGAATTT CCGCCAGCTCAGGCAGGCGTACCGGGATCAGGTGCTGGCCCTGCTGGAAGGGGGGGTGGACATGCTGCTGGTGGAGACGA TTTTCGACACGCTGAACGCCAAGGCAGCCCTGTTCGCCATTGAAGAAATTTTTGAGGAACAACCGGAAAGCTCTGTTCCG GTCATGGTATCCGTAACGCTGACGGACAAAGCCGGACGCACGCTGTCCGGCCAGACGATTGAAGCATTCTGGAACTCCAT CCGCCACGTTCGCCCCTTCTCCGTAGGCATCAATTGCGCCCTGGGGCCGGACCTGATGCGCCCCTTTGCGGAAGAACTGT CCGGACTGGCAGATTGCCACATGTCCATTTATGCGAATGCCGGGCTTCCCAACCCGCTCAGCCCTACCGGCTACGACCTT CTGCCGGCGGATATGGCCCGGTTCATGAAGGAATACGCGGAACAGGGCCTGCTGAACATCGTGGGCGGCTGCTGCGGAAC CACTCCGGAGCATATCGGCGCCATTGCGGCTGCCGTGGAAGGAATGCCTCCGCGCGTTCCGGCTCCCCAAACGCCCGCGC TTCGCCTGTCCGGATATGAAGCGTACAACCATACGCGGGAAAAAAACACCCTCTTTGTCGGGGAACGCTGCAATGTGGCG GGTTCCCCCAAATTCGCCCGCCTGATTCGTGAAGGAAATTACGAGGAAGCGGTATCCATTGCCCGGCAGCAGGTGGAAAA CGGCGCGCTGGTATTGGATTTCTGTTTTGACGACGGCCTGATCGACGGGCCGCAGGCCATGGTCCGCTTCCTGAACCTTG TTTCCGCAGAGCCGGATATCGCCCGCGTTCCTTTCATGGTGGATTCCTCCAAGTGGGAGGTGCTGGAAGCGGGGCTCCAA TGCATGCAGGGCAAGGGAATCGTGAATTCCATTTCTCTGAAGGAGGGGGAAGAAGAATTCCTGAAGAAAGCGGCGCTGAT TAAAAAGTACGGCGCAGCGGTCGTGGTCATGGCGTTTGACGAACAGGGACAGGCCGCCAATTACGAGGACCGCGTCCGCA TCTCCAGACGGGCCTATGACTTGCTGGTAAACCGGGTGCAGTTTCCTCCGGAAGACATCATTTTTGACCCGAACGTCCTG ACCGTAGGCACCGGCATTGCGGAACACGCCGATTACGCTCTTGATTTCTTCAAGGCCGCAGGCTGGATCTCCCGGAACCT GCCGCATGCCCACATTTCCGGCGGCATTTCCAATGTCTCCTTTGCTTTCCGCGGCAACAACCCGGTGCGGGAAGCCATGC ATTCCGCTTTCCTGTACCACGCTACGCAGCAGGGGCTGGACATGTGCATCGTGAATGCCGGGATGCTGGAGGTGTACGAC AATATTCCCAAGGACAGGCTGGAGCTGATTGAAGACGTTCTGCTGAACCGGAGGACGGACGCCACGGAACGCCTGACGGA TTACGCGGAAAAACTGGCTGCGGAAAAAACCGGAGACGGAAAGGAGAAAAAAACCGTACAGGCCTGGAGGGAGCAGGACG TTGCCAAACGTCTGGAATATTCTCTTATCAAGGGCATTACCGAATTTGTTGACGCGGATACGGAGGAGGCTTTTCAGGAG CTGGGGTCTCCGCTGAACGTGATTGAAGGCCCTCTGATGGCCGGCATGAAGGTCGTCGGGCAACTGTTCGGGGACGGCAA AATGTTCCTGCCGCAGGTGGTGAAAAGCGCCCGCGTCATGAAACAGGCTGTAGCCTGGCTCACCCCCTATATAGAAGCGG ACAGCAAAGGAGCCGCCAAGGCGGGAAAAGCCGTGATCGCCACCGTGAAGGGGGACGTGCATGACATCGGCAAAAATATC GTCGGCGTGGTGTTGAGCTGCAATGGTTTTGAAATGATTGACCTGGGCGTCATGGTCCATTGCGATACCATTCTGGACCG GGCGGAAGCGGAACAGGCGGACCTGGTGATGCTTTCCGGGCTGATCACCCCTTCCCTGGAAGAGATGTCCCATGTAGCCG CGGAGATGGAACGCCGGGGGATGACCATTCCCCTGATGGTGGGGGGAGCTACGACGTCAGCCCTGCATACGGCCCTGAAA ATAGCCCCCCATTATCAAGGAGCCGTGGTGCATACGGAGGATGCCTCCCAGGTGGTTCCCGCAGCCGCCTCCCTGGTGGG AGAAAAAAAGGATTCCTACATTGCCGCCGTGAAGGCCCGGCAGGAGGAATTGCGCAACAATCATGAAAACAAACCCGTCC GGGACCTCCTGCCCCTGGAGAAAGCCAGGGAATTGCGCTGGAAGGGAGCGGAAGGCGGCTATCTCCCCCCCGTTCCCGCC CGTCTTGGCCCGGTTTCCATCGGCAGCCTGCACAGCTCCGTAAGCTGCGGCTGCTGCAGTGACGATCCACGTTATTACGT AACTGTTCAGGAGCTTATCGAGCGCATGGACTGGACGCCTTTTTTCCACGCCTGGGAGCTGCACGGCACATGGGACCGCG CCCGCCGGGAGTTCCGCACCAAAGACCCGTCCAAGGCTGAGGCGGCCGCGGCGCTGTACCAGGACGCCCTCCGCTTGCTG GAACAGGCCGTGAAGGAAAACCGCTACCAGGCGCGCGGCGTCATAGGCATTTTCCCGGCCAATTCAACAGCCAGCCATGA CGACATCACCGTCTGGGCTGATGAATCCAGAACCATTCCCCTGGCTACGCTGCTGACGCAGCGCCAGCAACTGGACAAAC AGGGGAAACCCCGGCTGGCGCTGGCGGACTTCATCGCTCCCGAAGGCGTCAGGGATTACGTGGGGGCCATGGCGGTCAGC ATCCACGGCTCCCGCCGCTGGGCAAAGGAATGGGAAGCCAGAAACGACTCCTACCGCGCCCTGCTGGTCAGCTCTCTGGC GGACCGCCTGGTGGAGGCTTTCGCGGCCATCGCCCATGACAAGCTGCGCCTTTTGTGGAATATTCCGGAAGGGTCCGGCG TGCGACCTGCCTGCGGGTACCCCAGCCAGCCGGACCACCAGGAAAAGGAAACCGTCTTCACCCTGCTCCACGCCCGGGAG GAAGCGGGCATGAGCCTGACGGAAACATGGATGATGCAGCCCGTTTCTTCCGTCTGCGCCCTCGTCTTCTCCCATCCGGA AAGCACTTATTTCTCCGTGGGCGTCACCGGGGAAGACCAGCAGGAGGATTACGCCTCCAGAAAACGGGCCTCCCGGCCCT GA
Upstream 100 bases:
>100_bases GAAAACAGGTTCCTCCCATTTCCCCGGAGCAATACGGGAAAAACGTGACGACAATTGTCCTTGTTCCAATGACGGACGGA CGGTAGATTTTCCGCGCCAT
Downstream 100 bases:
>100_bases CCTCCCCTTTCCCTTTTATGCAGCATACCGACCAGATACAGGCCCTTTCGGAATTCCTGCTGGAATACGCCACCACCCTC ATGGGCGCGGGGGTGCACAC
Product: methionine synthase
Products: NA
Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]
Number of amino acids: Translated: 1253; Mature: 1252
Protein sequence:
>1253_residues MSRASRTERLDYLKDQLRKRVVILDGAMGTNIQKFRLGEGDYRGERFADAECYPNDLKNNNDLLVLTRPDIILDIHRRFL DTGRTDILETCTFGATSIGQHDYFWHRPEEGSHKDQQYFQEVVDAPELKALVRELNLAAAALARQACDEAEAADGKPRLV AGSIGPMPVTCSLSPDVNDPGFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEIFEEQPESSVP VMVSVTLTDKAGRTLSGQTIEAFWNSIRHVRPFSVGINCALGPDLMRPFAEELSGLADCHMSIYANAGLPNPLSPTGYDL LPADMARFMKEYAEQGLLNIVGGCCGTTPEHIGAIAAAVEGMPPRVPAPQTPALRLSGYEAYNHTREKNTLFVGERCNVA GSPKFARLIREGNYEEAVSIARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAEPDIARVPFMVDSSKWEVLEAGLQ CMQGKGIVNSISLKEGEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYDLLVNRVQFPPEDIIFDPNVL TVGTGIAEHADYALDFFKAAGWISRNLPHAHISGGISNVSFAFRGNNPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYD NIPKDRLELIEDVLLNRRTDATERLTDYAEKLAAEKTGDGKEKKTVQAWREQDVAKRLEYSLIKGITEFVDADTEEAFQE LGSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADSKGAAKAGKAVIATVKGDVHDIGKNI VGVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSGLITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALHTALK IAPHYQGAVVHTEDASQVVPAAASLVGEKKDSYIAAVKARQEELRNNHENKPVRDLLPLEKARELRWKGAEGGYLPPVPA RLGPVSIGSLHSSVSCGCCSDDPRYYVTVQELIERMDWTPFFHAWELHGTWDRARREFRTKDPSKAEAAAALYQDALRLL EQAVKENRYQARGVIGIFPANSTASHDDITVWADESRTIPLATLLTQRQQLDKQGKPRLALADFIAPEGVRDYVGAMAVS IHGSRRWAKEWEARNDSYRALLVSSLADRLVEAFAAIAHDKLRLLWNIPEGSGVRPACGYPSQPDHQEKETVFTLLHARE EAGMSLTETWMMQPVSSVCALVFSHPESTYFSVGVTGEDQQEDYASRKRASRP
Sequences:
>Translated_1253_residues MSRASRTERLDYLKDQLRKRVVILDGAMGTNIQKFRLGEGDYRGERFADAECYPNDLKNNNDLLVLTRPDIILDIHRRFL DTGRTDILETCTFGATSIGQHDYFWHRPEEGSHKDQQYFQEVVDAPELKALVRELNLAAAALARQACDEAEAADGKPRLV AGSIGPMPVTCSLSPDVNDPGFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEIFEEQPESSVP VMVSVTLTDKAGRTLSGQTIEAFWNSIRHVRPFSVGINCALGPDLMRPFAEELSGLADCHMSIYANAGLPNPLSPTGYDL LPADMARFMKEYAEQGLLNIVGGCCGTTPEHIGAIAAAVEGMPPRVPAPQTPALRLSGYEAYNHTREKNTLFVGERCNVA GSPKFARLIREGNYEEAVSIARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAEPDIARVPFMVDSSKWEVLEAGLQ CMQGKGIVNSISLKEGEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYDLLVNRVQFPPEDIIFDPNVL TVGTGIAEHADYALDFFKAAGWISRNLPHAHISGGISNVSFAFRGNNPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYD NIPKDRLELIEDVLLNRRTDATERLTDYAEKLAAEKTGDGKEKKTVQAWREQDVAKRLEYSLIKGITEFVDADTEEAFQE LGSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADSKGAAKAGKAVIATVKGDVHDIGKNI VGVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSGLITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALHTALK IAPHYQGAVVHTEDASQVVPAAASLVGEKKDSYIAAVKARQEELRNNHENKPVRDLLPLEKARELRWKGAEGGYLPPVPA RLGPVSIGSLHSSVSCGCCSDDPRYYVTVQELIERMDWTPFFHAWELHGTWDRARREFRTKDPSKAEAAAALYQDALRLL EQAVKENRYQARGVIGIFPANSTASHDDITVWADESRTIPLATLLTQRQQLDKQGKPRLALADFIAPEGVRDYVGAMAVS IHGSRRWAKEWEARNDSYRALLVSSLADRLVEAFAAIAHDKLRLLWNIPEGSGVRPACGYPSQPDHQEKETVFTLLHARE EAGMSLTETWMMQPVSSVCALVFSHPESTYFSVGVTGEDQQEDYASRKRASRP >Mature_1252_residues SRASRTERLDYLKDQLRKRVVILDGAMGTNIQKFRLGEGDYRGERFADAECYPNDLKNNNDLLVLTRPDIILDIHRRFLD TGRTDILETCTFGATSIGQHDYFWHRPEEGSHKDQQYFQEVVDAPELKALVRELNLAAAALARQACDEAEAADGKPRLVA GSIGPMPVTCSLSPDVNDPGFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEIFEEQPESSVPV MVSVTLTDKAGRTLSGQTIEAFWNSIRHVRPFSVGINCALGPDLMRPFAEELSGLADCHMSIYANAGLPNPLSPTGYDLL PADMARFMKEYAEQGLLNIVGGCCGTTPEHIGAIAAAVEGMPPRVPAPQTPALRLSGYEAYNHTREKNTLFVGERCNVAG SPKFARLIREGNYEEAVSIARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAEPDIARVPFMVDSSKWEVLEAGLQC MQGKGIVNSISLKEGEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYDLLVNRVQFPPEDIIFDPNVLT VGTGIAEHADYALDFFKAAGWISRNLPHAHISGGISNVSFAFRGNNPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYDN IPKDRLELIEDVLLNRRTDATERLTDYAEKLAAEKTGDGKEKKTVQAWREQDVAKRLEYSLIKGITEFVDADTEEAFQEL GSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADSKGAAKAGKAVIATVKGDVHDIGKNIV GVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSGLITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALHTALKI APHYQGAVVHTEDASQVVPAAASLVGEKKDSYIAAVKARQEELRNNHENKPVRDLLPLEKARELRWKGAEGGYLPPVPAR LGPVSIGSLHSSVSCGCCSDDPRYYVTVQELIERMDWTPFFHAWELHGTWDRARREFRTKDPSKAEAAAALYQDALRLLE QAVKENRYQARGVIGIFPANSTASHDDITVWADESRTIPLATLLTQRQQLDKQGKPRLALADFIAPEGVRDYVGAMAVSI HGSRRWAKEWEARNDSYRALLVSSLADRLVEAFAAIAHDKLRLLWNIPEGSGVRPACGYPSQPDHQEKETVFTLLHAREE AGMSLTETWMMQPVSSVCALVFSHPESTYFSVGVTGEDQQEDYASRKRASRP
Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]
COG id: COG1410
COG function: function code E; Methionine synthase I, cobalamin-binding domain
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 pterin-binding domain [H]
Homologues:
Organism=Homo sapiens, GI169790923, Length=1282, Percent_Identity=46.9578783151326, Blast_Score=1084, Evalue=0.0, Organism=Escherichia coli, GI1790450, Length=1268, Percent_Identity=49.8422712933754, Blast_Score=1181, Evalue=0.0, Organism=Caenorhabditis elegans, GI17535405, Length=1286, Percent_Identity=45.6454121306376, Blast_Score=1042, Evalue=0.0,
Paralogues:
None
Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006158 - InterPro: IPR011005 - InterPro: IPR003759 - InterPro: IPR011822 - InterPro: IPR000489 - InterPro: IPR003726 - InterPro: IPR004223 [H]
Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]
EC number: =2.1.1.13 [H]
Molecular weight: Translated: 138236; Mature: 138104
Theoretical pI: Translated: 5.18; Mature: 5.18
Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRASRTERLDYLKDQLRKRVVILDGAMGTNIQKFRLGEGDYRGERFADAECYPNDLKNN CCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC NDLLVLTRPDIILDIHRRFLDTGRTDILETCTFGATSIGQHDYFWHRPEEGSHKDQQYFQ CCEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH EVVDAPELKALVRELNLAAAALARQACDEAEAADGKPRLVAGSIGPMPVTCSLSPDVNDP HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCCC GFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEIFEEQPESSVP CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC VMVSVTLTDKAGRTLSGQTIEAFWNSIRHVRPFSVGINCALGPDLMRPFAEELSGLADCH EEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEECEEECCCHHHHHHHHHHHHHHHHHH MSIYANAGLPNPLSPTGYDLLPADMARFMKEYAEQGLLNIVGGCCGTTPEHIGAIAAAVE HHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHC GMPPRVPAPQTPALRLSGYEAYNHTREKNTLFVGERCNVAGSPKFARLIREGNYEEAVSI CCCCCCCCCCCCCEEECCCHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHH ARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAEPDIARVPFMVDSSKWEVLEAGLQ HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEECCEEECCCHHHHHHHHHH CMQGKGIVNSISLKEGEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYD HHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH LLVNRVQFPPEDIIFDPNVLTVGTGIAEHADYALDFFKAAGWISRNLPHAHISGGISNVS HHHHHHCCCCHHEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEE FAFRGNNPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYDNIPKDRLELIEDVLLNRRTD EEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCC ATERLTDYAEKLAAEKTGDGKEKKTVQAWREQDVAKRLEYSLIKGITEFVDADTEEAFQE HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH LGSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADSKGAAK CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH AGKAVIATVKGDVHDIGKNIVGVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSG CCCEEEEEECCCHHHHHHHHEEEEEECCCCEEEECCCEEEHHHHHHHHCCHHHCCHHHHH LITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALHTALKIAPHYQGAVVHTEDASQVVP CCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHH AAASLVGEKKDSYIAAVKARQEELRNNHENKPVRDLLPLEKARELRWKGAEGGYLPPVPA HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHCCCCCCCCCCCCCCC RLGPVSIGSLHSSVSCGCCSDDPRYYVTVQELIERMDWTPFFHAWELHGTWDRARREFRT CCCCCCHHHHHCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCC KDPSKAEAAAALYQDALRLLEQAVKENRYQARGVIGIFPANSTASHDDITVWADESRTIP CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCCCCCCCEEEEECCCCCCH LATLLTQRQQLDKQGKPRLALADFIAPEGVRDYVGAMAVSIHGSRRWAKEWEARNDSYRA HHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHEEEEECCCHHHHHHHHCCCCHHHH LLVSSLADRLVEAFAAIAHDKLRLLWNIPEGSGVRPACGYPSQPDHQEKETVFTLLHARE HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH EAGMSLTETWMMQPVSSVCALVFSHPESTYFSVGVTGEDQQEDYASRKRASRP HCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCC >Mature Secondary Structure SRASRTERLDYLKDQLRKRVVILDGAMGTNIQKFRLGEGDYRGERFADAECYPNDLKNN CCCHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCC NDLLVLTRPDIILDIHRRFLDTGRTDILETCTFGATSIGQHDYFWHRPEEGSHKDQQYFQ CCEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH EVVDAPELKALVRELNLAAAALARQACDEAEAADGKPRLVAGSIGPMPVTCSLSPDVNDP HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCCC GFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEIFEEQPESSVP CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC VMVSVTLTDKAGRTLSGQTIEAFWNSIRHVRPFSVGINCALGPDLMRPFAEELSGLADCH EEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEECEEECCCHHHHHHHHHHHHHHHHHH MSIYANAGLPNPLSPTGYDLLPADMARFMKEYAEQGLLNIVGGCCGTTPEHIGAIAAAVE HHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHC GMPPRVPAPQTPALRLSGYEAYNHTREKNTLFVGERCNVAGSPKFARLIREGNYEEAVSI CCCCCCCCCCCCCEEECCCHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHH ARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAEPDIARVPFMVDSSKWEVLEAGLQ HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEECCEEECCCHHHHHHHHHH CMQGKGIVNSISLKEGEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYD HHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH LLVNRVQFPPEDIIFDPNVLTVGTGIAEHADYALDFFKAAGWISRNLPHAHISGGISNVS HHHHHHCCCCHHEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEE FAFRGNNPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYDNIPKDRLELIEDVLLNRRTD EEEECCCHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCC ATERLTDYAEKLAAEKTGDGKEKKTVQAWREQDVAKRLEYSLIKGITEFVDADTEEAFQE HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH LGSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADSKGAAK CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH AGKAVIATVKGDVHDIGKNIVGVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSG CCCEEEEEECCCHHHHHHHHEEEEEECCCCEEEECCCEEEHHHHHHHHCCHHHCCHHHHH LITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALHTALKIAPHYQGAVVHTEDASQVVP CCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHH AAASLVGEKKDSYIAAVKARQEELRNNHENKPVRDLLPLEKARELRWKGAEGGYLPPVPA HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHCCCCCCCCCCCCCCC RLGPVSIGSLHSSVSCGCCSDDPRYYVTVQELIERMDWTPFFHAWELHGTWDRARREFRT CCCCCCHHHHHCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCC KDPSKAEAAAALYQDALRLLEQAVKENRYQARGVIGIFPANSTASHDDITVWADESRTIP CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCCCCCCCCEEEEECCCCCCH LATLLTQRQQLDKQGKPRLALADFIAPEGVRDYVGAMAVSIHGSRRWAKEWEARNDSYRA HHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHEEEEECCCHHHHHHHHCCCCHHHH LLVSSLADRLVEAFAAIAHDKLRLLWNIPEGSGVRPACGYPSQPDHQEKETVFTLLHARE HHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH EAGMSLTETWMMQPVSSVCALVFSHPESTYFSVGVTGEDQQEDYASRKRASRP HCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12620739 [H]