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The map label for this gene is queC [H]

Identifier: 187736368

GI number: 187736368

Start: 2290166

End: 2290837

Strand: Reverse

Name: queC [H]

Synonym: Amuc_1885

Alternate gene names: 187736368

Gene position: 2290837-2290166 (Counterclockwise)

Preceding gene: 187736369

Following gene: 187736365

Centisome position: 85.99

GC content: 61.01

Gene sequence:

>672_bases
ATGGACAAAATGGAAACAGCCGTACTGCTCAGCGGGGGATTGGACTCCAGCGTAGCCCTGCACTGGGCCCACCGGAACCA
CCGCGTCCGGGTGGCCCTCAGCTTTGACTATGCCTCCAACCACGCGGAACGAGAGCTGAAATGCGCTGCCTGGCAGGCCG
CCAGTCTGGGCATAGAACACCGCGTGATTGACATTTCCTCCATCTCCTCCCATTTGAAATCAGCCCTCCTCTCCGGCGCG
GACGATATTCCGGACGGTTCCTATGATGAAGAACTGATGAAGCAGACCGTCGTCCCCTTCCGCAACGGCATCTTCCTGTC
AATCGCCGCCGGGGTTGCGGAAAGCTGCGGGGCGCAGCAGCTCGTCATTGCGGCCCATTCCGGGGACCATAGCATCTATC
CGGACTGCCGGGAGGAATTCATGGCCGCCATGACGGAAGCCATTCGCTTGGGAACCTATGCCGGCCTGGGCATCCTGCGC
CCTTTCATCCACATGTCCAAGGGCGGCATCGCCGCCATGGGCCAGGATTTGGGCGTGGACTTTTCCCGTACCTATTCCTG
CTACAAGGGCGGAGCCGTCCACTGCGGCGTCTGTTCCACCTGCATGGAACGCCGGGAAGCCTTCAGGGAAGCCGGAATTC
CGGATCCAACGGCTTATGCGCCTGCGGAATAG

Upstream 100 bases:

>100_bases
GGTGGCTGAAGGTGGAAGGCCGCTTCTCCCCCCGCGGCGGCATCCAGCTGACCGCAACAGCCGAACACAATCCGGAAAAC
CGCCCCCTGTAATCCAGACC

Downstream 100 bases:

>100_bases
CATCCAAATGCCAGGAATGAAACGCTAAGGAAAAATCCCCGGCCTATGGCCGAAAGGAGATGCCTATGCCCCAATGACAT
CGGGGAAACGCATGGAAAGA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MDKMETAVLLSGGLDSSVALHWAHRNHRVRVALSFDYASNHAERELKCAAWQAASLGIEHRVIDISSISSHLKSALLSGA
DDIPDGSYDEELMKQTVVPFRNGIFLSIAAGVAESCGAQQLVIAAHSGDHSIYPDCREEFMAAMTEAIRLGTYAGLGILR
PFIHMSKGGIAAMGQDLGVDFSRTYSCYKGGAVHCGVCSTCMERREAFREAGIPDPTAYAPAE

Sequences:

>Translated_223_residues
MDKMETAVLLSGGLDSSVALHWAHRNHRVRVALSFDYASNHAERELKCAAWQAASLGIEHRVIDISSISSHLKSALLSGA
DDIPDGSYDEELMKQTVVPFRNGIFLSIAAGVAESCGAQQLVIAAHSGDHSIYPDCREEFMAAMTEAIRLGTYAGLGILR
PFIHMSKGGIAAMGQDLGVDFSRTYSCYKGGAVHCGVCSTCMERREAFREAGIPDPTAYAPAE
>Mature_223_residues
MDKMETAVLLSGGLDSSVALHWAHRNHRVRVALSFDYASNHAERELKCAAWQAASLGIEHRVIDISSISSHLKSALLSGA
DDIPDGSYDEELMKQTVVPFRNGIFLSIAAGVAESCGAQQLVIAAHSGDHSIYPDCREEFMAAMTEAIRLGTYAGLGILR
PFIHMSKGGIAAMGQDLGVDFSRTYSCYKGGAVHCGVCSTCMERREAFREAGIPDPTAYAPAE

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=218, Percent_Identity=30.2752293577982, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 23979; Mature: 23979

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKMETAVLLSGGLDSSVALHWAHRNHRVRVALSFDYASNHAERELKCAAWQAASLGIEH
CCCHHEEEEEECCCCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
RVIDISSISSHLKSALLSGADDIPDGSYDEELMKQTVVPFRNGIFLSIAAGVAESCGAQQ
EEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCE
LVIAAHSGDHSIYPDCREEFMAAMTEAIRLGTYAGLGILRPFIHMSKGGIAAMGQDLGVD
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHCCCC
FSRTYSCYKGGAVHCGVCSTCMERREAFREAGIPDPTAYAPAE
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDKMETAVLLSGGLDSSVALHWAHRNHRVRVALSFDYASNHAERELKCAAWQAASLGIEH
CCCHHEEEEEECCCCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCC
RVIDISSISSHLKSALLSGADDIPDGSYDEELMKQTVVPFRNGIFLSIAAGVAESCGAQQ
EEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCE
LVIAAHSGDHSIYPDCREEFMAAMTEAIRLGTYAGLGILRPFIHMSKGGIAAMGQDLGVD
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHCCCC
FSRTYSCYKGGAVHCGVCSTCMERREAFREAGIPDPTAYAPAE
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA