Definition | Akkermansia muciniphila ATCC BAA-835, complete genome. |
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Accession | NC_010655 |
Length | 2,664,102 |
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The map label for this gene is yejB [H]
Identifier: 187736338
GI number: 187736338
Start: 2256435
End: 2257823
Strand: Reverse
Name: yejB [H]
Synonym: Amuc_1855
Alternate gene names: 187736338
Gene position: 2257823-2256435 (Counterclockwise)
Preceding gene: 187736339
Following gene: 187736337
Centisome position: 84.75
GC content: 54.72
Gene sequence:
>1389_bases ATGAAGACCTATATCATCAGACGACTCCTTCTCATGCCCTTGACGCTCCTGGGGGTTACGTTTCTCGTCTTTTGCATAAC CCGTTTTGTTCCGGGAGGTCCCATTGAGCAGATGATGCAGCAGCAAAGCATGAGCGCCCTGTCCGGACAGAAAGCCGGCT CCCAGCGCGGCGACAATAACCTGAGTGAAGCGGATATGGAGCGGCTGGAAGAGCAGTACAGCCTGCAGGAGCCCATCATC ACGGCTTATCTGCAATGGCTGGGCGTGCTGCCCAAAAAGATTTTCATTTCCCGTGAGGAATTCGGGGAAATCGGCGGAGC GGGAGAGGGAGACAAGGAAGATGAATATTCCGGCATTTCCGATACGCATACACGGATCAATCTGAATGAAACAGGAGAAC AAGTCGTCGTAGTTCGCCAGGACAAGGATTCCGGCAGCGTGAAAGATGCTTTCTTTTCCGGCACGCCGTCCCGGAAAGCC GCTTCAGAAGGCTGGACCGTGGATATAGAATCCCCCATGGACCGCGCGGAACGCTGGGCGCGCCGCATGAGGCAGACGGA TAATACGGAGGCCGTCCGCGACAAGGCTCGGGGCTATGCCTGGCGTGCCGTAATGTACAAGACCAGCTTTGACGGGCTGC TCCAGGGAACTATGGGCAACTCATTTAAGTACAATGAACCCGTATGGGACATGATTAAGGAGCGCATTCCCGTTTCCCTG TACTTCGGCATCCTGAGCGCCATTATTACCTATTCCGTCTGCATTCCCCTTGGGGTAGTAAAGGCAATCCGCCATAAAAG CCTGGTGGACAACATCTCTTCCGTCCTGATTTTCCTGGGGTACTCCGTGCCTGGGTTCGCCCTGGGAGCCGTACTGGTGG TGTATCTGGGCGCGCGGCTGGAATGGTTCCCTCTCTGCGGGCTTACGTCTCCGGACTTTGCGGACATGGGGTTCTGGCAA CAGGCCGGAGACCTGCTGCACCATACGGTGCTCCCCCTGATTTGTTATGTAGTAAGTTCCTTTGCCATCACCACCATGAT GATGAAAAACAACCTGATGGACAATCTTTCCGCGGACTACATCAGGACAGCCATGGCCAAGGGCGTGAGTTTCAGAGGGG CCGTCATCAAGCATGCCTTCCGTAACTCCTTTATACCCATTGCCTCCACTCTGGGCAGCCTCATTAGCCTGATTGTGGCC GGCTCCATGCTGGTGGAAAAAGTTTTCGATATCCAGGGGTTCGGGATGCTGAGTTACCAGGCTCTGATGGACAAGGATTA CGCCCTGATCATGGGAACGCTGCTGCTTACCTCCTTCCTGATGGTACTGGGCAACCTTCTCTCCGATATCATCGTGGCCG CTGTGGATCCGCGCATCAAATTTGAATAA
Upstream 100 bases:
>100_bases CTTAAGAAGAACCGGGCAGCACCTTATGTTAGCAAAGGCTTACAAATTTGCATTGCTACTTGCCTCACCTTCCACAAATC GGTAGAGTTCAGCGCGACGA
Downstream 100 bases:
>100_bases TACACATGGTTAGAAAACTGGCATACCTTTTGGTCATTCTGGCGGTTCTTACTGCCGTGGGAGAGCTGTGCGGGCTGCTC CTGCCCACGTTAAGCTGGCC
Product: binding-protein-dependent transporters inner membrane component
Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 462; Mature: 462
Protein sequence:
>462_residues MKTYIIRRLLLMPLTLLGVTFLVFCITRFVPGGPIEQMMQQQSMSALSGQKAGSQRGDNNLSEADMERLEEQYSLQEPII TAYLQWLGVLPKKIFISREEFGEIGGAGEGDKEDEYSGISDTHTRINLNETGEQVVVVRQDKDSGSVKDAFFSGTPSRKA ASEGWTVDIESPMDRAERWARRMRQTDNTEAVRDKARGYAWRAVMYKTSFDGLLQGTMGNSFKYNEPVWDMIKERIPVSL YFGILSAIITYSVCIPLGVVKAIRHKSLVDNISSVLIFLGYSVPGFALGAVLVVYLGARLEWFPLCGLTSPDFADMGFWQ QAGDLLHHTVLPLICYVVSSFAITTMMMKNNLMDNLSADYIRTAMAKGVSFRGAVIKHAFRNSFIPIASTLGSLISLIVA GSMLVEKVFDIQGFGMLSYQALMDKDYALIMGTLLLTSFLMVLGNLLSDIIVAAVDPRIKFE
Sequences:
>Translated_462_residues MKTYIIRRLLLMPLTLLGVTFLVFCITRFVPGGPIEQMMQQQSMSALSGQKAGSQRGDNNLSEADMERLEEQYSLQEPII TAYLQWLGVLPKKIFISREEFGEIGGAGEGDKEDEYSGISDTHTRINLNETGEQVVVVRQDKDSGSVKDAFFSGTPSRKA ASEGWTVDIESPMDRAERWARRMRQTDNTEAVRDKARGYAWRAVMYKTSFDGLLQGTMGNSFKYNEPVWDMIKERIPVSL YFGILSAIITYSVCIPLGVVKAIRHKSLVDNISSVLIFLGYSVPGFALGAVLVVYLGARLEWFPLCGLTSPDFADMGFWQ QAGDLLHHTVLPLICYVVSSFAITTMMMKNNLMDNLSADYIRTAMAKGVSFRGAVIKHAFRNSFIPIASTLGSLISLIVA GSMLVEKVFDIQGFGMLSYQALMDKDYALIMGTLLLTSFLMVLGNLLSDIIVAAVDPRIKFE >Mature_462_residues MKTYIIRRLLLMPLTLLGVTFLVFCITRFVPGGPIEQMMQQQSMSALSGQKAGSQRGDNNLSEADMERLEEQYSLQEPII TAYLQWLGVLPKKIFISREEFGEIGGAGEGDKEDEYSGISDTHTRINLNETGEQVVVVRQDKDSGSVKDAFFSGTPSRKA ASEGWTVDIESPMDRAERWARRMRQTDNTEAVRDKARGYAWRAVMYKTSFDGLLQGTMGNSFKYNEPVWDMIKERIPVSL YFGILSAIITYSVCIPLGVVKAIRHKSLVDNISSVLIFLGYSVPGFALGAVLVVYLGARLEWFPLCGLTSPDFADMGFWQ QAGDLLHHTVLPLICYVVSSFAITTMMMKNNLMDNLSADYIRTAMAKGVSFRGAVIKHAFRNSFIPIASTLGSLISLIVA GSMLVEKVFDIQGFGMLSYQALMDKDYALIMGTLLLTSFLMVLGNLLSDIIVAAVDPRIKFE
Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]
COG id: COG4174
COG function: function code R; ABC-type uncharacterized transport system, permease component
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transmembrane type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1788504, Length=248, Percent_Identity=38.7096774193548, Blast_Score=180, Evalue=2e-46, Organism=Escherichia coli, GI1789965, Length=267, Percent_Identity=30.7116104868914, Blast_Score=144, Evalue=9e-36, Organism=Escherichia coli, GI1787053, Length=249, Percent_Identity=32.1285140562249, Blast_Score=129, Evalue=5e-31, Organism=Escherichia coli, GI1787497, Length=257, Percent_Identity=26.4591439688716, Blast_Score=116, Evalue=3e-27, Organism=Escherichia coli, GI1789888, Length=257, Percent_Identity=27.2373540856031, Blast_Score=109, Evalue=3e-25, Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=25.2747252747253, Blast_Score=99, Evalue=5e-22, Organism=Escherichia coli, GI1787761, Length=261, Percent_Identity=27.2030651340996, Blast_Score=91, Evalue=2e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000515 [H]
Pfam domain/function: PF00528 BPD_transp_1 [H]
EC number: NA
Molecular weight: Translated: 51337; Mature: 51337
Theoretical pI: Translated: 6.08; Mature: 6.08
Prosite motif: PS50928 ABC_TM1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 4.8 %Met (Translated Protein) 5.6 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 4.8 %Met (Mature Protein) 5.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTYIIRRLLLMPLTLLGVTFLVFCITRFVPGGPIEQMMQQQSMSALSGQKAGSQRGDNN CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC LSEADMERLEEQYSLQEPIITAYLQWLGVLPKKIFISREEFGEIGGAGEGDKEDEYSGIS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHCCCCCCCCCCCCCCCCCC DTHTRINLNETGEQVVVVRQDKDSGSVKDAFFSGTPSRKAASEGWTVDIESPMDRAERWA CCCCEEEECCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHH RRMRQTDNTEAVRDKARGYAWRAVMYKTSFDGLLQGTMGNSFKYNEPVWDMIKERIPVSL HHHHCCCCHHHHHHHHCCCEEHHHEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHH YFGILSAIITYSVCIPLGVVKAIRHKSLVDNISSVLIFLGYSVPGFALGAVLVVYLGARL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC EWFPLCGLTSPDFADMGFWQQAGDLLHHTVLPLICYVVSSFAITTMMMKNNLMDNLSADY CEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IRTAMAKGVSFRGAVIKHAFRNSFIPIASTLGSLISLIVAGSMLVEKVFDIQGFGMLSYQ HHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH ALMDKDYALIMGTLLLTSFLMVLGNLLSDIIVAAVDPRIKFE HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure MKTYIIRRLLLMPLTLLGVTFLVFCITRFVPGGPIEQMMQQQSMSALSGQKAGSQRGDNN CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC LSEADMERLEEQYSLQEPIITAYLQWLGVLPKKIFISREEFGEIGGAGEGDKEDEYSGIS CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHCCCCCCCCCCCCCCCCCC DTHTRINLNETGEQVVVVRQDKDSGSVKDAFFSGTPSRKAASEGWTVDIESPMDRAERWA CCCCEEEECCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHH RRMRQTDNTEAVRDKARGYAWRAVMYKTSFDGLLQGTMGNSFKYNEPVWDMIKERIPVSL HHHHCCCCHHHHHHHHCCCEEHHHEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHH YFGILSAIITYSVCIPLGVVKAIRHKSLVDNISSVLIFLGYSVPGFALGAVLVVYLGARL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC EWFPLCGLTSPDFADMGFWQQAGDLLHHTVLPLICYVVSSFAITTMMMKNNLMDNLSADY CEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IRTAMAKGVSFRGAVIKHAFRNSFIPIASTLGSLISLIVAGSMLVEKVFDIQGFGMLSYQ HHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH ALMDKDYALIMGTLLLTSFLMVLGNLLSDIIVAAVDPRIKFE HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; oligopeptides [Periplasm]; H2O [C]
Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]