The gene/protein map for NC_010655 is currently unavailable.
Definition Akkermansia muciniphila ATCC BAA-835, complete genome.
Accession NC_010655
Length 2,664,102

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The map label for this gene is yejE [H]

Identifier: 187736337

GI number: 187736337

Start: 2254822

End: 2256429

Strand: Reverse

Name: yejE [H]

Synonym: Amuc_1854

Alternate gene names: 187736337

Gene position: 2256429-2254822 (Counterclockwise)

Preceding gene: 187736338

Following gene: 187736336

Centisome position: 84.7

GC content: 55.1

Gene sequence:

>1608_bases
ATGGTTAGAAAACTGGCATACCTTTTGGTCATTCTGGCGGTTCTTACTGCCGTGGGAGAGCTGTGCGGGCTGCTCCTGCC
CACGTTAAGCTGGCCCTTCACCGTCTCACGGGAAATGAGCATGCTCAACATCGTCTGTACGGACCAGAACAACGGCGGCC
TTCTGACGCCTCAGGGGAAATTCCTGTGGTTCGGCTGGGTTTGCGTGCTGGTCATGGGAGGCCTCGGGTTCTGGCTCATG
CTGAAAGGCCCCCGGAGGTTCCATCCAACGCCGATCACCAGGCGCCGCATCCAGCGTTTTAAAAGCATCTCCCGCGGTTA
CGTATCCCTCCTCATTTTGCTTGTATTGACGCTATTGGCCTGTATGGACCAGTGCCTGGTGGGCAAGCGGGCCCTCCTTG
TCGTTCAGGACGGATCCTGGTACTTTCCGGCCATGATGCGCAAAGTATACAAGGGTTCTACATTTGGCCAGACCGGAGAT
TTTGCGGATGCGGAAGCCAACTACCGCGAACTGAAAAAACAGGCAGGCCAGCCGGGAAAACCCTCCCTTGTCATCATGCC
TCTGGTTCCATACGATCCCACGGGAGATTCCACCAACCCCGGTTCGGAAGCTTTGATGGTGAATGAAGACGGTCTCGTCT
GCGAGGCCGGCGGCAAGCCGTATTCCGGTTTGGCCTCCCGTTTGCATAAGGATGAAGAAGCCCTTCCCCACATCAGCTAC
AAATTCCGCAAGGGAAAGAAAGTGGACCGGGCCACCGGCTGGCTGGAAGACAGAACGGAGGTGTACAGCGCCACGTATGA
AAACAACAACATTGTGGCGGAACATTACAGCGGCCCCGGCACCAAAGAGGAATTCCTGAAACAGACGGATGAACATAAAA
TCAGCCGTATCTTCTACCACCCCTCCCCGCCCCTCAAGGGGGGCCACCTGCTTGGCACCAATACCCAGGGGGCGGACATT
CTGGCTTATCTGTACGGCGGCCTCCAAGTAAATATGAAAGCCGCACTCTTCTACCTGCCTATCGTATATTTCATCGGCAT
CACCTTTGGAATGATGATGGGATACTTCGGCGGCATGTTTGACCTCGGCATGCAGCGCCTCATTGAAATCTTCTCCCAGG
TTCCCTTCCTTTTCATCATCATGATTATTTCAGATATGGTTCCCCTTCATATGAAGGGCATGTTCCTGATTATCAGCCTT
CTAATCATGTTCGGGTGGATGTCCATGACCTACCAGCTCAGAACCTCCACCATGAAGGAAAAAGCGCGCGACTACGTGGC
GGCCGCCCGCGTGCTTGGGGCTTCCACCAGCCGTATTCTCTTCGTTCATATCCTGCCCAACCTAGTCGCCATTCTGGTCA
CTCTGGTTCCGTTCAGCGTTTCCGCCCTCATTCTGGCTCTGGCTTCCCTGGACTATCTGGGCTTCGGCCTTCCTGACACA
TACGCCAGCTGGGGGCGCCTGCTCAATGACGGACTGGCGGATCTTTCCGCCAGCTGGGTGGTTACCTCCGCCTTTTCCGC
CCTGGTGATTACCCTCCTGCTCGTCACCTTTATCGGGGAGGCTGTCCGCGAAGCCTTTGACCCTAAAAAATTCACCACTT
ATAAATAA

Upstream 100 bases:

>100_bases
GAACGCTGCTGCTTACCTCCTTCCTGATGGTACTGGGCAACCTTCTCTCCGATATCATCGTGGCCGCTGTGGATCCGCGC
ATCAAATTTGAATAATACAC

Downstream 100 bases:

>100_bases
AAAGACTCCCGCTTTGCCATTTCTTATGCTTAAGCTGTCCACCCTCCTCCGTTCCACCCTTTCTTCCGTGATGCTGTCCC
TTCTGTTGACAGCCGGGTCC

Product: binding-protein-dependent transporters inner membrane component

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MVRKLAYLLVILAVLTAVGELCGLLLPTLSWPFTVSREMSMLNIVCTDQNNGGLLTPQGKFLWFGWVCVLVMGGLGFWLM
LKGPRRFHPTPITRRRIQRFKSISRGYVSLLILLVLTLLACMDQCLVGKRALLVVQDGSWYFPAMMRKVYKGSTFGQTGD
FADAEANYRELKKQAGQPGKPSLVIMPLVPYDPTGDSTNPGSEALMVNEDGLVCEAGGKPYSGLASRLHKDEEALPHISY
KFRKGKKVDRATGWLEDRTEVYSATYENNNIVAEHYSGPGTKEEFLKQTDEHKISRIFYHPSPPLKGGHLLGTNTQGADI
LAYLYGGLQVNMKAALFYLPIVYFIGITFGMMMGYFGGMFDLGMQRLIEIFSQVPFLFIIMIISDMVPLHMKGMFLIISL
LIMFGWMSMTYQLRTSTMKEKARDYVAAARVLGASTSRILFVHILPNLVAILVTLVPFSVSALILALASLDYLGFGLPDT
YASWGRLLNDGLADLSASWVVTSAFSALVITLLLVTFIGEAVREAFDPKKFTTYK

Sequences:

>Translated_535_residues
MVRKLAYLLVILAVLTAVGELCGLLLPTLSWPFTVSREMSMLNIVCTDQNNGGLLTPQGKFLWFGWVCVLVMGGLGFWLM
LKGPRRFHPTPITRRRIQRFKSISRGYVSLLILLVLTLLACMDQCLVGKRALLVVQDGSWYFPAMMRKVYKGSTFGQTGD
FADAEANYRELKKQAGQPGKPSLVIMPLVPYDPTGDSTNPGSEALMVNEDGLVCEAGGKPYSGLASRLHKDEEALPHISY
KFRKGKKVDRATGWLEDRTEVYSATYENNNIVAEHYSGPGTKEEFLKQTDEHKISRIFYHPSPPLKGGHLLGTNTQGADI
LAYLYGGLQVNMKAALFYLPIVYFIGITFGMMMGYFGGMFDLGMQRLIEIFSQVPFLFIIMIISDMVPLHMKGMFLIISL
LIMFGWMSMTYQLRTSTMKEKARDYVAAARVLGASTSRILFVHILPNLVAILVTLVPFSVSALILALASLDYLGFGLPDT
YASWGRLLNDGLADLSASWVVTSAFSALVITLLLVTFIGEAVREAFDPKKFTTYK
>Mature_535_residues
MVRKLAYLLVILAVLTAVGELCGLLLPTLSWPFTVSREMSMLNIVCTDQNNGGLLTPQGKFLWFGWVCVLVMGGLGFWLM
LKGPRRFHPTPITRRRIQRFKSISRGYVSLLILLVLTLLACMDQCLVGKRALLVVQDGSWYFPAMMRKVYKGSTFGQTGD
FADAEANYRELKKQAGQPGKPSLVIMPLVPYDPTGDSTNPGSEALMVNEDGLVCEAGGKPYSGLASRLHKDEEALPHISY
KFRKGKKVDRATGWLEDRTEVYSATYENNNIVAEHYSGPGTKEEFLKQTDEHKISRIFYHPSPPLKGGHLLGTNTQGADI
LAYLYGGLQVNMKAALFYLPIVYFIGITFGMMMGYFGGMFDLGMQRLIEIFSQVPFLFIIMIISDMVPLHMKGMFLIISL
LIMFGWMSMTYQLRTSTMKEKARDYVAAARVLGASTSRILFVHILPNLVAILVTLVPFSVSALILALASLDYLGFGLPDT
YASWGRLLNDGLADLSASWVVTSAFSALVITLLLVTFIGEAVREAFDPKKFTTYK

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4239

COG function: function code R; ABC-type uncharacterized transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=38.695652173913, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787498, Length=230, Percent_Identity=32.1739130434783, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1789964, Length=234, Percent_Identity=31.6239316239316, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787054, Length=223, Percent_Identity=28.6995515695067, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1787549, Length=222, Percent_Identity=28.3783783783784, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787760, Length=227, Percent_Identity=25.1101321585903, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789889, Length=233, Percent_Identity=24.0343347639485, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 59477; Mature: 59477

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKLAYLLVILAVLTAVGELCGLLLPTLSWPFTVSREMSMLNIVCTDQNNGGLLTPQGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEEEEECCCCCCEECCCCC
FLWFGWVCVLVMGGLGFWLMLKGPRRFHPTPITRRRIQRFKSISRGYVSLLILLVLTLLA
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CMDQCLVGKRALLVVQDGSWYFPAMMRKVYKGSTFGQTGDFADAEANYRELKKQAGQPGK
HHHHHHCCCCEEEEEECCCEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
PSLVIMPLVPYDPTGDSTNPGSEALMVNEDGLVCEAGGKPYSGLASRLHKDEEALPHISY
CCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEECCCCCCHHHHHHHHCCHHHHCCCCHH
KFRKGKKVDRATGWLEDRTEVYSATYENNNIVAEHYSGPGTKEEFLKQTDEHKISRIFYH
HHHCCCCHHHHHCCHHHHHHHHHEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEEC
PSPPLKGGHLLGTNTQGADILAYLYGGLQVNMKAALFYLPIVYFIGITFGMMMGYFGGMF
CCCCCCCCEEECCCCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLGMQRLIEIFSQVPFLFIIMIISDMVPLHMKGMFLIISLLIMFGWMSMTYQLRTSTMKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARDYVAAARVLGASTSRILFVHILPNLVAILVTLVPFSVSALILALASLDYLGFGLPDT
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YASWGRLLNDGLADLSASWVVTSAFSALVITLLLVTFIGEAVREAFDPKKFTTYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVRKLAYLLVILAVLTAVGELCGLLLPTLSWPFTVSREMSMLNIVCTDQNNGGLLTPQGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEEEEEECCCCCCEECCCCC
FLWFGWVCVLVMGGLGFWLMLKGPRRFHPTPITRRRIQRFKSISRGYVSLLILLVLTLLA
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CMDQCLVGKRALLVVQDGSWYFPAMMRKVYKGSTFGQTGDFADAEANYRELKKQAGQPGK
HHHHHHCCCCEEEEEECCCEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
PSLVIMPLVPYDPTGDSTNPGSEALMVNEDGLVCEAGGKPYSGLASRLHKDEEALPHISY
CCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEECCCCCCHHHHHHHHCCHHHHCCCCHH
KFRKGKKVDRATGWLEDRTEVYSATYENNNIVAEHYSGPGTKEEFLKQTDEHKISRIFYH
HHHCCCCHHHHHCCHHHHHHHHHEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHEEEEC
PSPPLKGGHLLGTNTQGADILAYLYGGLQVNMKAALFYLPIVYFIGITFGMMMGYFGGMF
CCCCCCCCEEECCCCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLGMQRLIEIFSQVPFLFIIMIISDMVPLHMKGMFLIISLLIMFGWMSMTYQLRTSTMKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARDYVAAARVLGASTSRILFVHILPNLVAILVTLVPFSVSALILALASLDYLGFGLPDT
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YASWGRLLNDGLADLSASWVVTSAFSALVITLLLVTFIGEAVREAFDPKKFTTYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]