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The map label for this gene is aas [H]

Identifier: 187736207

GI number: 187736207

Start: 2091197

End: 2093359

Strand: Reverse

Name: aas [H]

Synonym: Amuc_1720

Alternate gene names: 187736207

Gene position: 2093359-2091197 (Counterclockwise)

Preceding gene: 187736212

Following gene: 187736206

Centisome position: 78.58

GC content: 56.59

Gene sequence:

>2163_bases
ATGGCCATTTTTGGTTCCTCCAATTTATCCGACTCAGGTGATCTGTTGATCTTCAACAAAGTATCTTATAAAACCCTACT
GATGTTCGAAAAAGAACTGGGCAGGGACCGCATGACCTACCTGGTGGAAGAAGGTCTCCCCCCGGATACGGCCACCGCCT
CCCATCTGGAATCCACTAAAGCGGACGGCATCCTGTTCCAGGCCGGAGGCAGCGACCCTGTCGCGCTGCGTTCCGCCATC
ATGGAACGCATTAACGAAGGCAGAAGAGTAGTATTTCTGCCCGGTCCCGTCTCCCATGTGAAAGGTTCCATCAGCCAAAT
TCCTCCGCGGGTCATCAAGGCCCTGGAAGCCCTGCATATTTCCCCCGTACCGGTCTATGCCGGTTTTTACACGAACTCCG
TGCTGGATGCGGAGGCCGATACGGACGCCCAGGCGGACATCCAGATACATATTCTCCCCAAACTGGCCCCCGGGGCCGAG
ATGGCAGCACGCCTGACCTCCGCGTGGCTGGAATGTTCCGCCCAGGCATACGCCACGCTGCCTCAGCTCCACGGTTCCCT
GTCCGCCCTCCTTTTCCGCAGCCTCAAACTTCATTCCGATTGCCGGGTCATCGACGGCATTGATGACACTACGCTGACTT
ACGGCCAGCTGCTGGCCATTTCCGTAGCCTTTGCCAAGAGGTTGAAAAAAATTACCTCGAATCGCCGGGTCGGCATCATT
CTTCCGCCGGGCAAGGGAGCGGCCATAGCCAATCTGGGCTGCCTGTTCGCCGGGAAAACACCGGTGAATTTCAATTATTC
CGCTTCGGAAGGAGCCTTTGCCAGCTCTGTAAAGCAATCCGGCGTGGACTGGTTTATTACTGCGGATACCTTCATGCGAA
AGCTCCAGAATTTCCCGTGGCCCCCCCAGCGGGATCTGATCCTCATGGAGCGGGAAATTCCCCTGCTTAAAGGTTCCGCC
AAACGCTGGGGCCTCGCCATCAAATTCCTGACAGCGGGGTTCATGATTAAAAAACTGGGGCTGGACGCGCCTACAGGCGC
GGACGAAGCCGTTCTGATGTTCACTTCCGGCTCTTCCGGGGAACCCAAGGGCGTGCCGCTGACCCACCATAACCTTCTTT
CCAACATCTCTCAATGTTCCTCCCGCATTACGCTGGAACCGCAAAACAGGTTTCTGGGAAGCCTGCCCGTATTCCACTGC
TTCGGCATCACCATCGGGCTATGGTATCCGATGATCGGCGGGTACGACATGGTCACCTACCCCTCCCCTCTTGAGGCCAA
ACGGCTGGGAGCCCTTATCAAGCAGTACGGAATCAGTCTGGTAGTCACCACGCCCACTTTCCTGCGCGGTTTCATGAAAC
GCTGCGAACCGGACACCTTTAAAACCGTCCGCTACCTGATCGTTGGCGCGGAAAAACTGCCGGAAGACCTTTCCATCGCT
TTCCGGGAAAAATTCGGCATTATTCCATGTGAAGGCTACGGCCTGACGGAAGCCTCTCCCGTCTGTTCCGTCAACTTCAT
TGACCCGGCGCCATCCAATGCCGCCGGAGACTTCATTCCCGGCATGAAAAAGAGTTCCGTAGGAGCCCTCCTTCCCGGAA
TCGCCATACGCATCACCAGCCCTCACACGGGACGCGTGGTTCCCATCACTACTTCCGGCATGATCTGGCTGAAAGGACCG
AACATCTTTCCCGGCTATCTGGGCGGTCCGGAGACGGATCGCGATATTTTCGTGGACGGCTGGCTAAAAACCGGAGACAT
AGGTTCCGCAGACGAATTCGGCTTCCTGAAGATTGAAGGACGCATTTCCCGCTTTTCCAAAATAGGCGGGGAAATGGTGC
CTCATGAAGCCCTGGAAGCAGCCATTATGAACATTTGGAATCTGGATCCGGCGGACGAAGAACGGCGGATAGCCGTCGTC
ACCATTCCGGATCCCGTAAAAGGGGAAGCCGTAGCCCTGCTCACCACCCTGGTGACGGATTACGTGCACCAGGCGCGAAC
CCTCATCAGGCACGGCCTGATTGACCAGGGTCTGCCGGCCCTCTGGTGCCCCAAGGAGATTATTCCCGTAGAACGCATCC
CGGTGCTCCCATCCGGCAAGCTGGATATCAAGCAATGCAGGATGCTGGCGTATGAAGCGCTGAACATCCCCTTTGAACCG
TAA

Upstream 100 bases:

>100_bases
ATCCGGATAAAGGAAAAGCAACCGGGAATGCACCTTTCCTCCTTGCTCCCGGTTCTTCAAGTTGCTAAAATGCTTCAAGC
AAATTTTTTATCCTTTTCCC

Downstream 100 bases:

>100_bases
TTTATGGAATTCCCGGAGGAAACGCCCGCCGCGCCCAAACCCATCACAGTCAAACAGCTCGTTTACCGCCTGAGGGACAC
GGTCAGCATCGCTATGGGCA

Product: AMP-dependent synthetase and ligase

Products: NA

Alternate protein names: 2-acylglycerophosphoethanolamine acyltransferase; 2-acyl-GPE acyltransferase; Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase; Acyl-[acyl-carrier-protein] synthetase; Acyl-ACP synthetase; Long-chain-fatty-acid--[acyl-carrier-protein] ligase [H]

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MAIFGSSNLSDSGDLLIFNKVSYKTLLMFEKELGRDRMTYLVEEGLPPDTATASHLESTKADGILFQAGGSDPVALRSAI
MERINEGRRVVFLPGPVSHVKGSISQIPPRVIKALEALHISPVPVYAGFYTNSVLDAEADTDAQADIQIHILPKLAPGAE
MAARLTSAWLECSAQAYATLPQLHGSLSALLFRSLKLHSDCRVIDGIDDTTLTYGQLLAISVAFAKRLKKITSNRRVGII
LPPGKGAAIANLGCLFAGKTPVNFNYSASEGAFASSVKQSGVDWFITADTFMRKLQNFPWPPQRDLILMEREIPLLKGSA
KRWGLAIKFLTAGFMIKKLGLDAPTGADEAVLMFTSGSSGEPKGVPLTHHNLLSNISQCSSRITLEPQNRFLGSLPVFHC
FGITIGLWYPMIGGYDMVTYPSPLEAKRLGALIKQYGISLVVTTPTFLRGFMKRCEPDTFKTVRYLIVGAEKLPEDLSIA
FREKFGIIPCEGYGLTEASPVCSVNFIDPAPSNAAGDFIPGMKKSSVGALLPGIAIRITSPHTGRVVPITTSGMIWLKGP
NIFPGYLGGPETDRDIFVDGWLKTGDIGSADEFGFLKIEGRISRFSKIGGEMVPHEALEAAIMNIWNLDPADEERRIAVV
TIPDPVKGEAVALLTTLVTDYVHQARTLIRHGLIDQGLPALWCPKEIIPVERIPVLPSGKLDIKQCRMLAYEALNIPFEP

Sequences:

>Translated_720_residues
MAIFGSSNLSDSGDLLIFNKVSYKTLLMFEKELGRDRMTYLVEEGLPPDTATASHLESTKADGILFQAGGSDPVALRSAI
MERINEGRRVVFLPGPVSHVKGSISQIPPRVIKALEALHISPVPVYAGFYTNSVLDAEADTDAQADIQIHILPKLAPGAE
MAARLTSAWLECSAQAYATLPQLHGSLSALLFRSLKLHSDCRVIDGIDDTTLTYGQLLAISVAFAKRLKKITSNRRVGII
LPPGKGAAIANLGCLFAGKTPVNFNYSASEGAFASSVKQSGVDWFITADTFMRKLQNFPWPPQRDLILMEREIPLLKGSA
KRWGLAIKFLTAGFMIKKLGLDAPTGADEAVLMFTSGSSGEPKGVPLTHHNLLSNISQCSSRITLEPQNRFLGSLPVFHC
FGITIGLWYPMIGGYDMVTYPSPLEAKRLGALIKQYGISLVVTTPTFLRGFMKRCEPDTFKTVRYLIVGAEKLPEDLSIA
FREKFGIIPCEGYGLTEASPVCSVNFIDPAPSNAAGDFIPGMKKSSVGALLPGIAIRITSPHTGRVVPITTSGMIWLKGP
NIFPGYLGGPETDRDIFVDGWLKTGDIGSADEFGFLKIEGRISRFSKIGGEMVPHEALEAAIMNIWNLDPADEERRIAVV
TIPDPVKGEAVALLTTLVTDYVHQARTLIRHGLIDQGLPALWCPKEIIPVERIPVLPSGKLDIKQCRMLAYEALNIPFEP
>Mature_719_residues
AIFGSSNLSDSGDLLIFNKVSYKTLLMFEKELGRDRMTYLVEEGLPPDTATASHLESTKADGILFQAGGSDPVALRSAIM
ERINEGRRVVFLPGPVSHVKGSISQIPPRVIKALEALHISPVPVYAGFYTNSVLDAEADTDAQADIQIHILPKLAPGAEM
AARLTSAWLECSAQAYATLPQLHGSLSALLFRSLKLHSDCRVIDGIDDTTLTYGQLLAISVAFAKRLKKITSNRRVGIIL
PPGKGAAIANLGCLFAGKTPVNFNYSASEGAFASSVKQSGVDWFITADTFMRKLQNFPWPPQRDLILMEREIPLLKGSAK
RWGLAIKFLTAGFMIKKLGLDAPTGADEAVLMFTSGSSGEPKGVPLTHHNLLSNISQCSSRITLEPQNRFLGSLPVFHCF
GITIGLWYPMIGGYDMVTYPSPLEAKRLGALIKQYGISLVVTTPTFLRGFMKRCEPDTFKTVRYLIVGAEKLPEDLSIAF
REKFGIIPCEGYGLTEASPVCSVNFIDPAPSNAAGDFIPGMKKSSVGALLPGIAIRITSPHTGRVVPITTSGMIWLKGPN
IFPGYLGGPETDRDIFVDGWLKTGDIGSADEFGFLKIEGRISRFSKIGGEMVPHEALEAAIMNIWNLDPADEERRIAVVT
IPDPVKGEAVALLTTLVTDYVHQARTLIRHGLIDQGLPALWCPKEIIPVERIPVLPSGKLDIKQCRMLAYEALNIPFEP

Specific function: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=381, Percent_Identity=25.9842519685039, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI187761345, Length=391, Percent_Identity=27.3657289002558, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI187761343, Length=391, Percent_Identity=27.3657289002558, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI40807491, Length=329, Percent_Identity=24.9240121580547, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI42544132, Length=534, Percent_Identity=22.4719101123595, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1789201, Length=671, Percent_Identity=28.7630402384501, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1788107, Length=504, Percent_Identity=24.6031746031746, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI145693145, Length=359, Percent_Identity=26.4623955431755, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI221142682, Length=364, Percent_Identity=27.1978021978022, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786801, Length=283, Percent_Identity=24.3816254416961, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558820, Length=509, Percent_Identity=26.3261296660118, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17559526, Length=317, Percent_Identity=29.9684542586751, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32563687, Length=533, Percent_Identity=27.2045028142589, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17557194, Length=390, Percent_Identity=27.4358974358974, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538037, Length=384, Percent_Identity=25.5208333333333, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71985884, Length=316, Percent_Identity=25.6329113924051, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=527, Percent_Identity=22.9601518026565, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=356, Percent_Identity=23.314606741573, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994690, Length=451, Percent_Identity=21.5077605321508, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994703, Length=451, Percent_Identity=21.5077605321508, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=451, Percent_Identity=21.5077605321508, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17531443, Length=369, Percent_Identity=23.8482384823848, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71996755, Length=464, Percent_Identity=23.4913793103448, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319699, Length=367, Percent_Identity=23.1607629427793, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859661, Length=528, Percent_Identity=27.6515151515151, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21355181, Length=364, Percent_Identity=27.7472527472527, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24581924, Length=359, Percent_Identity=27.8551532033426, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161076582, Length=556, Percent_Identity=23.5611510791367, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653035, Length=347, Percent_Identity=24.7838616714697, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF01553 Acyltransferase; PF00501 AMP-binding [H]

EC number: =2.3.1.40; =6.2.1.20 [H]

Molecular weight: Translated: 78243; Mature: 78112

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFGSSNLSDSGDLLIFNKVSYKTLLMFEKELGRDRMTYLVEEGLPPDTATASHLESTK
CEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHCC
ADGILFQAGGSDPVALRSAIMERINEGRRVVFLPGPVSHVKGSISQIPPRVIKALEALHI
CCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCHHHCCHHHHHHHHHHCC
SPVPVYAGFYTNSVLDAEADTDAQADIQIHILPKLAPGAEMAARLTSAWLECSAQAYATL
CCCCEEECCCCCCEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHH
PQLHGSLSALLFRSLKLHSDCRVIDGIDDTTLTYGQLLAISVAFAKRLKKITSNRRVGII
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LPPGKGAAIANLGCLFAGKTPVNFNYSASEGAFASSVKQSGVDWFITADTFMRKLQNFPW
ECCCCCCCEEECEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHCCCC
PPQRDLILMEREIPLLKGSAKRWGLAIKFLTAGFMIKKLGLDAPTGADEAVLMFTSGSSG
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EPKGVPLTHHNLLSNISQCSSRITLEPQNRFLGSLPVFHCFGITIGLWYPMIGGYDMVTY
CCCCCCEEHHHHHHHHHHHHHEEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECC
PSPLEAKRLGALIKQYGISLVVTTPTFLRGFMKRCEPDTFKTVRYLIVGAEKLPEDLSIA
CCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHCCCCHHHHHHHHEECHHHCCHHHHHH
FREKFGIIPCEGYGLTEASPVCSVNFIDPAPSNAAGDFIPGMKKSSVGALLPGIAIRITS
HHHHCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEC
PHTGRVVPITTSGMIWLKGPNIFPGYLGGPETDRDIFVDGWLKTGDIGSADEFGFLKIEG
CCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCCEEEEEEC
RISRFSKIGGEMVPHEALEAAIMNIWNLDPADEERRIAVVTIPDPVKGEAVALLTTLVTD
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
YVHQARTLIRHGLIDQGLPALWCPKEIIPVERIPVLPSGKLDIKQCRMLAYEALNIPFEP
HHHHHHHHHHHCHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AIFGSSNLSDSGDLLIFNKVSYKTLLMFEKELGRDRMTYLVEEGLPPDTATASHLESTK
EEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHCC
ADGILFQAGGSDPVALRSAIMERINEGRRVVFLPGPVSHVKGSISQIPPRVIKALEALHI
CCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCHHHCCHHHHHHHHHHCC
SPVPVYAGFYTNSVLDAEADTDAQADIQIHILPKLAPGAEMAARLTSAWLECSAQAYATL
CCCCEEECCCCCCEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHHH
PQLHGSLSALLFRSLKLHSDCRVIDGIDDTTLTYGQLLAISVAFAKRLKKITSNRRVGII
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LPPGKGAAIANLGCLFAGKTPVNFNYSASEGAFASSVKQSGVDWFITADTFMRKLQNFPW
ECCCCCCCEEECEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHCCCC
PPQRDLILMEREIPLLKGSAKRWGLAIKFLTAGFMIKKLGLDAPTGADEAVLMFTSGSSG
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EPKGVPLTHHNLLSNISQCSSRITLEPQNRFLGSLPVFHCFGITIGLWYPMIGGYDMVTY
CCCCCCEEHHHHHHHHHHHHHEEEECCHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECC
PSPLEAKRLGALIKQYGISLVVTTPTFLRGFMKRCEPDTFKTVRYLIVGAEKLPEDLSIA
CCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHHHCCCCHHHHHHHHEECHHHCCHHHHHH
FREKFGIIPCEGYGLTEASPVCSVNFIDPAPSNAAGDFIPGMKKSSVGALLPGIAIRITS
HHHHCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEEEC
PHTGRVVPITTSGMIWLKGPNIFPGYLGGPETDRDIFVDGWLKTGDIGSADEFGFLKIEG
CCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCCEEEEEEC
RISRFSKIGGEMVPHEALEAAIMNIWNLDPADEERRIAVVTIPDPVKGEAVALLTTLVTD
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
YVHQARTLIRHGLIDQGLPALWCPKEIIPVERIPVLPSGKLDIKQCRMLAYEALNIPFEP
HHHHHHHHHHHCHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA