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The map label for this gene is xseA [H]

Identifier: 187736206

GI number: 187736206

Start: 2089829

End: 2091193

Strand: Reverse

Name: xseA [H]

Synonym: Amuc_1719

Alternate gene names: 187736206

Gene position: 2091193-2089829 (Counterclockwise)

Preceding gene: 187736207

Following gene: 187736205

Centisome position: 78.5

GC content: 56.48

Gene sequence:

>1365_bases
ATGGAATTCCCGGAGGAAACGCCCGCCGCGCCCAAACCCATCACAGTCAAACAGCTCGTTTACCGCCTGAGGGACACGGT
CAGCATCGCTATGGGCACCCAGTGGGTGGTGGGAGAACTGAGTAACGTCAAGCATCACACCAGCGGCCACGTTTATTTCA
CCCTGAAGGAACAGGGAGCGGAAATTTTCTGCGCCTTTTTCAAGGCAGCGGCTTCCAAATGCCCCATACGGCTCCAGGAA
GGGATGAAAGTCCATGTCCTGGGCAGCGCCACCGTATACCCGGACCGGGGGCAACTCCAGCTGGTCATCAGGCAGGTAAA
AGCTGCAGGACAGGGAGATTTGCAGACTCGCTTTTTGGAGTTGAAAGCCAAACTCCAGCGCGAGGGGTTGTTTGATGCGG
AACACAAAAAGAAAATTCCCACGTTCCCCCGCGCCATCGGCATCGTCACCTCCCCCACCGGCGCCGTCATCCAGGACATG
CGGCACGTATTGGAACGCCGCGCCCCGTGGGTGAAGGCTTATCTGCTGCCCATACGCGTGCAGGGGGCAGGAGCGGAGCA
CGAAATAGCCGCAGCCGTGCGCGCTTGGTCCGGAGCCCCCTTTAACGGTCTCCCTCCCGTGGACGTGCTCATTGTAGGCC
GCGGCGGCGGCTCCATTGAGGATTTGTGGAATTTCAATGAGGAAACGGTGGCGCGCGCCATTTACGAATGTACCGTTCCC
GTGATTTCCGCAGTGGGTCATGATACGGACTTCACCATTGCCGATTTTGTAGCGGATCTGCGCGCTCCCACTCCCACTGC
AGCCGCGGAACTGGCCACACCGGACGGCCCCGAATGGCTCCGCAAGCTGTCCAGAATGGAACAGGCTCTTCATGCATCCG
CTCGGCATTCCCTCTTGCGTTCCAAGCTGAAACTGGATGTTTACCTGCGAGGGAAACTGTTGGATGCGTATTCCCTGCTC
TCTCCTTATTCTCAGCGCCTGGACGATATGGAAGAAACTCTGCAGAATGCCGCAACCACGAGAATTTTTCATAATGCGCT
GCATATTAACAAATTGGAACATCAACTGCAAATGCGCCATCCCGCCCACAGGAACCGGGAGCGTACACAGCTTCTGGCTT
CCCTTCAGGCCGGTTTATCCCATGCTGCCGCCGCCCGCATGACGGATTTATCTTCACAACTCACTCTTATTCAAGCACGT
CTTGAAGCACACAGCCCGGAACAGACCCTGCGCCGCGGATATGCCCTGGTGGAAAACCAGGATAAGCAGCTTATCCGGCA
GACAAACCAGGTGCATGCAGGGGAAAAATTGAAAATCCGTGTTTCCGACGGTTGTTTTTATGTCAGGGATGACACGCCAC
AATAA

Upstream 100 bases:

>100_bases
CGTAGAACGCATCCCGGTGCTCCCATCCGGCAAGCTGGATATCAAGCAATGCAGGATGCTGGCGTATGAAGCGCTGAACA
TCCCCTTTGAACCGTAATTT

Downstream 100 bases:

>100_bases
CCTGTCCACAAGCATCTAGTAGTGCATTTTTTGCACTCAATCTAACAAATTGTGTTTTTTCTGGATTTTACAGGAAATGG
AACTTATTCTAATAGAAGTT

Product: exodeoxyribonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MEFPEETPAAPKPITVKQLVYRLRDTVSIAMGTQWVVGELSNVKHHTSGHVYFTLKEQGAEIFCAFFKAAASKCPIRLQE
GMKVHVLGSATVYPDRGQLQLVIRQVKAAGQGDLQTRFLELKAKLQREGLFDAEHKKKIPTFPRAIGIVTSPTGAVIQDM
RHVLERRAPWVKAYLLPIRVQGAGAEHEIAAAVRAWSGAPFNGLPPVDVLIVGRGGGSIEDLWNFNEETVARAIYECTVP
VISAVGHDTDFTIADFVADLRAPTPTAAAELATPDGPEWLRKLSRMEQALHASARHSLLRSKLKLDVYLRGKLLDAYSLL
SPYSQRLDDMEETLQNAATTRIFHNALHINKLEHQLQMRHPAHRNRERTQLLASLQAGLSHAAAARMTDLSSQLTLIQAR
LEAHSPEQTLRRGYALVENQDKQLIRQTNQVHAGEKLKIRVSDGCFYVRDDTPQ

Sequences:

>Translated_454_residues
MEFPEETPAAPKPITVKQLVYRLRDTVSIAMGTQWVVGELSNVKHHTSGHVYFTLKEQGAEIFCAFFKAAASKCPIRLQE
GMKVHVLGSATVYPDRGQLQLVIRQVKAAGQGDLQTRFLELKAKLQREGLFDAEHKKKIPTFPRAIGIVTSPTGAVIQDM
RHVLERRAPWVKAYLLPIRVQGAGAEHEIAAAVRAWSGAPFNGLPPVDVLIVGRGGGSIEDLWNFNEETVARAIYECTVP
VISAVGHDTDFTIADFVADLRAPTPTAAAELATPDGPEWLRKLSRMEQALHASARHSLLRSKLKLDVYLRGKLLDAYSLL
SPYSQRLDDMEETLQNAATTRIFHNALHINKLEHQLQMRHPAHRNRERTQLLASLQAGLSHAAAARMTDLSSQLTLIQAR
LEAHSPEQTLRRGYALVENQDKQLIRQTNQVHAGEKLKIRVSDGCFYVRDDTPQ
>Mature_454_residues
MEFPEETPAAPKPITVKQLVYRLRDTVSIAMGTQWVVGELSNVKHHTSGHVYFTLKEQGAEIFCAFFKAAASKCPIRLQE
GMKVHVLGSATVYPDRGQLQLVIRQVKAAGQGDLQTRFLELKAKLQREGLFDAEHKKKIPTFPRAIGIVTSPTGAVIQDM
RHVLERRAPWVKAYLLPIRVQGAGAEHEIAAAVRAWSGAPFNGLPPVDVLIVGRGGGSIEDLWNFNEETVARAIYECTVP
VISAVGHDTDFTIADFVADLRAPTPTAAAELATPDGPEWLRKLSRMEQALHASARHSLLRSKLKLDVYLRGKLLDAYSLL
SPYSQRLDDMEETLQNAATTRIFHNALHINKLEHQLQMRHPAHRNRERTQLLASLQAGLSHAAAARMTDLSSQLTLIQAR
LEAHSPEQTLRRGYALVENQDKQLIRQTNQVHAGEKLKIRVSDGCFYVRDDTPQ

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=446, Percent_Identity=37.4439461883408, Blast_Score=278, Evalue=7e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50559; Mature: 50559

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFPEETPAAPKPITVKQLVYRLRDTVSIAMGTQWVVGELSNVKHHTSGHVYFTLKEQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEECCCH
EIFCAFFKAAASKCPIRLQEGMKVHVLGSATVYPDRGQLQLVIRQVKAAGQGDLQTRFLE
HHHHHHHHHHHHCCCEEHHCCCEEEEEECEEECCCCCHHHHHHHHHHCCCCCHHHHHHHH
LKAKLQREGLFDAEHKKKIPTFPRAIGIVTSPTGAVIQDMRHVLERRAPWVKAYLLPIRV
HHHHHHHCCCCCCHHHCCCCCCCHHEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEE
QGAGAEHEIAAAVRAWSGAPFNGLPPVDVLIVGRGGGSIEDLWNFNEETVARAIYECTVP
ECCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHH
VISAVGHDTDFTIADFVADLRAPTPTAAAELATPDGPEWLRKLSRMEQALHASARHSLLR
HHHHCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKLKLDVYLRGKLLDAYSLLSPYSQRLDDMEETLQNAATTRIFHNALHINKLEHQLQMRH
HHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAHRNRERTQLLASLQAGLSHAAAARMTDLSSQLTLIQARLEAHSPEQTLRRGYALVENQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHCCC
DKQLIRQTNQVHAGEKLKIRVSDGCFYVRDDTPQ
HHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCC
>Mature Secondary Structure
MEFPEETPAAPKPITVKQLVYRLRDTVSIAMGTQWVVGELSNVKHHTSGHVYFTLKEQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEECCCH
EIFCAFFKAAASKCPIRLQEGMKVHVLGSATVYPDRGQLQLVIRQVKAAGQGDLQTRFLE
HHHHHHHHHHHHCCCEEHHCCCEEEEEECEEECCCCCHHHHHHHHHHCCCCCHHHHHHHH
LKAKLQREGLFDAEHKKKIPTFPRAIGIVTSPTGAVIQDMRHVLERRAPWVKAYLLPIRV
HHHHHHHCCCCCCHHHCCCCCCCHHEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEE
QGAGAEHEIAAAVRAWSGAPFNGLPPVDVLIVGRGGGSIEDLWNFNEETVARAIYECTVP
ECCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHH
VISAVGHDTDFTIADFVADLRAPTPTAAAELATPDGPEWLRKLSRMEQALHASARHSLLR
HHHHCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKLKLDVYLRGKLLDAYSLLSPYSQRLDDMEETLQNAATTRIFHNALHINKLEHQLQMRH
HHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PAHRNRERTQLLASLQAGLSHAAAARMTDLSSQLTLIQARLEAHSPEQTLRRGYALVENQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHCCC
DKQLIRQTNQVHAGEKLKIRVSDGCFYVRDDTPQ
HHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA