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The map label for this gene is sucC

Identifier: 187736200

GI number: 187736200

Start: 2081594

End: 2082775

Strand: Reverse

Name: sucC

Synonym: Amuc_1713

Alternate gene names: 187736200

Gene position: 2082775-2081594 (Counterclockwise)

Preceding gene: 187736205

Following gene: 187736199

Centisome position: 78.18

GC content: 56.94

Gene sequence:

>1182_bases
ATGAACATTCACGAATATCAAGCAAAACAACTCTTTGAGCGTTTTGGCGTGGCAACCCCCAAGGGCATTGCCGCCTCCAC
AGCTCAGGAAGCAGCACAAACGGCCCGGAACATGGGCCTCTCCCAATACGTAGTTAAGGCACAGGTACACGCTGGCGGCC
GTGGTAAAGGCACCTTCAAAAACGGCTTTAAGGGAGGCGTCCACGTCGTCAAGTCCGTGGAAGAAGTGGAAGAAGTTGCC
GGCAAAATGCTCAACCAGGTTCTGGTCACCAAGCAAACCGGGGAAGCCGGCAAGCTGGTCAGCAAAATCATGGTGGCGGA
AGCCGTGGATCTCAAAAAGGAATGCTACTTCGCTATCCTTCAGGACCGCGCCCGGGAATGCCCCGTTATCGTGGCCAGTA
CGGAAGGCGGCATGGACATTGAAGAAGTGGCCGCCACCCGCCCGGAAGCCATTATCCGCGAACACATTAATCCGGCGCTG
GGCATCCTGCCTTTCCAGGCTCTCAAAATCGCCGTGGCGCTGGAACTGACCGGCCCCCTGCTCCGCCAGGCCACCAAGCT
TATCACCAACGTTTACAAGCTTTTCACCGCTCTGGACTGCTCCCTGGTGGAAATCAACCCCCTGGTAGTCACCACAGATG
ACCGCGTGTGTGCCCTGGACGCCAAATTCAATTTTGACGACAACGCCCTGTATCGCCACCCGGAAATCATGGAAATGCGG
GATGAAACTGAAGAAGACCCCCGTGAAGTGGAAGCCGGCAAGTACGACCTGAACTACATCGGCCTGGACGGCAACATTGG
CTGCATGGTGAACGGCGCCGGCCTGGCCATGGCCACGATGGACATCATCAAATACTACGGCGGAGAACCCGCCAACTTCC
TGGACGTAGGCGGTTCCGCCACGGAGGAAATGGTAACTAATGCGTTCCGCATCCTCACCAGCGACAAGAATGTGAAGGCC
CTTCTGGTCAATATCTTCGGCGGCATCATGCGCTGTGACGTCATCGCCCAGGGCATTGTGGCCGCGGCGAAAAACATCGA
CATGAAAATCCCGCTCGTCGTCCGCCTGGAAGGCACCAACGTGGAAATCGGCAAGAAAATCCTCGCAGACAGCGGCATCG
CCATCATCCCTGCCGACAACCTGGACGAAGCCGCCCAGAAAGCGGTGGCAGCAGTCAAATAA

Upstream 100 bases:

>100_bases
CCGGACAAAAAATCAAAAGACCAAACCATTCTCCCTTGACCGACACCAAAAATAGGCCTAGCCTTTCTTCCGCAAACATT
TGGCCAAACGGCCCACTGTC

Downstream 100 bases:

>100_bases
CCCTCACTATTTATTACGACAATGACATCTCTCATTGACAAGAACACTCGTCTGGTCGTGCAAGGCATCACCGGCAGCGC
CGGCGCATTCCACGCCAAAA

Product: succinyl-CoA synthetase, beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNIHEYQAKQLFERFGVATPKGIAASTAQEAAQTARNMGLSQYVVKAQVHAGGRGKGTFKNGFKGGVHVVKSVEEVEEVA
GKMLNQVLVTKQTGEAGKLVSKIMVAEAVDLKKECYFAILQDRARECPVIVASTEGGMDIEEVAATRPEAIIREHINPAL
GILPFQALKIAVALELTGPLLRQATKLITNVYKLFTALDCSLVEINPLVVTTDDRVCALDAKFNFDDNALYRHPEIMEMR
DETEEDPREVEAGKYDLNYIGLDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGSATEEMVTNAFRILTSDKNVKA
LLVNIFGGIMRCDVIAQGIVAAAKNIDMKIPLVVRLEGTNVEIGKKILADSGIAIIPADNLDEAAQKAVAAVK

Sequences:

>Translated_393_residues
MNIHEYQAKQLFERFGVATPKGIAASTAQEAAQTARNMGLSQYVVKAQVHAGGRGKGTFKNGFKGGVHVVKSVEEVEEVA
GKMLNQVLVTKQTGEAGKLVSKIMVAEAVDLKKECYFAILQDRARECPVIVASTEGGMDIEEVAATRPEAIIREHINPAL
GILPFQALKIAVALELTGPLLRQATKLITNVYKLFTALDCSLVEINPLVVTTDDRVCALDAKFNFDDNALYRHPEIMEMR
DETEEDPREVEAGKYDLNYIGLDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGSATEEMVTNAFRILTSDKNVKA
LLVNIFGGIMRCDVIAQGIVAAAKNIDMKIPLVVRLEGTNVEIGKKILADSGIAIIPADNLDEAAQKAVAAVK
>Mature_393_residues
MNIHEYQAKQLFERFGVATPKGIAASTAQEAAQTARNMGLSQYVVKAQVHAGGRGKGTFKNGFKGGVHVVKSVEEVEEVA
GKMLNQVLVTKQTGEAGKLVSKIMVAEAVDLKKECYFAILQDRARECPVIVASTEGGMDIEEVAATRPEAIIREHINPAL
GILPFQALKIAVALELTGPLLRQATKLITNVYKLFTALDCSLVEINPLVVTTDDRVCALDAKFNFDDNALYRHPEIMEMR
DETEEDPREVEAGKYDLNYIGLDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGSATEEMVTNAFRILTSDKNVKA
LLVNIFGGIMRCDVIAQGIVAAAKNIDMKIPLVVRLEGTNVEIGKKILADSGIAIIPADNLDEAAQKAVAAVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=51.6709511568123, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=50.9138381201044, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=51.3812154696133, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI1786948, Length=393, Percent_Identity=51.9083969465649, Blast_Score=394, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=52.0304568527919, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=48.9690721649485, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=48.7244897959184, Blast_Score=393, Evalue=1e-110,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=52.6992287917738, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=52.6992287917738, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=52.4173027989822, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=52.4173027989822, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI21356231, Length=393, Percent_Identity=50.381679389313, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24658419, Length=69, Percent_Identity=46.3768115942029, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_AKKM8 (B2UMH5)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001878312.1
- ProteinModelPortal:   B2UMH5
- SMR:   B2UMH5
- GeneID:   6274528
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1713
- HOGENOM:   HBG315432
- OMA:   TDRVTLM
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42341; Mature: 42341

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKQLFERFGVATPKGIAASTAQEAAQTARNMGLSQYVVKAQVHAGGRGKGTFK
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCCCC
NGFKGGVHVVKSVEEVEEVAGKMLNQVLVTKQTGEAGKLVSKIMVAEAVDLKKECYFAIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QDRARECPVIVASTEGGMDIEEVAATRPEAIIREHINPALGILPFQALKIAVALELTGPL
HHHHCCCCEEEEECCCCCCHHHHHHCCHHHHHHHHCCHHHHHCHHHHHHEEEEEECCCHH
LRQATKLITNVYKLFTALDCSLVEINPLVVTTDDRVCALDAKFNFDDNALYRHPEIMEMR
HHHHHHHHHHHHHHHHHHCCEEEEECEEEEECCCCEEEEEEECCCCCCCEECCCHHHHHH
DETEEDPREVEAGKYDLNYIGLDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGSA
HCCCCCCHHHCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCH
TEEMVTNAFRILTSDKNVKALLVNIFGGIMRCDVIAQGIVAAAKNIDMKIPLVVRLEGTN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEECCC
VEIGKKILADSGIAIIPADNLDEAAQKAVAAVK
CHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKQLFERFGVATPKGIAASTAQEAAQTARNMGLSQYVVKAQVHAGGRGKGTFK
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCCCC
NGFKGGVHVVKSVEEVEEVAGKMLNQVLVTKQTGEAGKLVSKIMVAEAVDLKKECYFAIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QDRARECPVIVASTEGGMDIEEVAATRPEAIIREHINPALGILPFQALKIAVALELTGPL
HHHHCCCCEEEEECCCCCCHHHHHHCCHHHHHHHHCCHHHHHCHHHHHHEEEEEECCCHH
LRQATKLITNVYKLFTALDCSLVEINPLVVTTDDRVCALDAKFNFDDNALYRHPEIMEMR
HHHHHHHHHHHHHHHHHHCCEEEEECEEEEECCCCEEEEEEECCCCCCCEECCCHHHHHH
DETEEDPREVEAGKYDLNYIGLDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGSA
HCCCCCCHHHCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCH
TEEMVTNAFRILTSDKNVKALLVNIFGGIMRCDVIAQGIVAAAKNIDMKIPLVVRLEGTN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEECCC
VEIGKKILADSGIAIIPADNLDEAAQKAVAAVK
CHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA