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The map label for this gene is rarA [H]

Identifier: 187736155

GI number: 187736155

Start: 2020324

End: 2021715

Strand: Reverse

Name: rarA [H]

Synonym: Amuc_1668

Alternate gene names: 187736155

Gene position: 2021715-2020324 (Counterclockwise)

Preceding gene: 187736157

Following gene: 187736152

Centisome position: 75.89

GC content: 60.42

Gene sequence:

>1392_bases
ATGATGGGCATCATGAAAAAAGACGACATCCCGGGCCTGTTCTCCGCCTTGGCGGACCGCCCTCTGGCGGACCGCCTGAG
GCCGTCCGCACTGGAAGACATCATGGGCCAGGATCATCTGCTGGGGGAAGGAGGACCTCTCCGGCTCATGGCGGACTCCG
GCAAGATGACCAGCTTTATCCTATGGGGGCCGCCCGGCTGCGGGAAAACCACGCTGGCGCGCATTCTGGCGACGCGCACA
TCCATGCATTTCGCAGCTCTCTCCGCCGTCTTCTCCGGCATGGCGGATTTGAGAAAAGCCTTTGACGAAGCGGCCAGGCG
CAGGGAATACGGCCATGGGACCCTCCTGTTCGTGGATGAAATACATCGGTTCAACCGCGCCCAGCAGGACGGTTTTCTGC
CATATGTGGAAAACGGAACCGTTACGCTGGTGGGGGCCACTACGGAAAACCCCTCCTTTGAACTGAACAGCGCCCTCCTC
TCCCGCTGCAAAGTCTTCGTCATGCACTCCCTGGACGCCCCGGCTCTGGAAAGCATCATTGAACGGGCGGAAACCCTTCT
TCAGCGTGAACTGCCGCTCGCGCCGGAAGCGCGCGCCACCCTGATAGAACTGGCAGACGGAGACGGCCGCTACCTCATTA
ACCTGATGGAAAGCGTCTTTGACCTCTGCAAGCCCGATGAAATGCTGGGCACGGACGCACTGCTGAAAATTGTCCAGCAG
CGAGCCCCGGTTTACGACAAGGACCGGGAAGGCCATTACAATCTCATCAGCGCCCTGCATAAATCCCTGCGGGGGTCGGA
TACGGACGCAGCCCTGTACTGGGCCGCACGCATGCTCGAGGGCGGGGAGGATCCTCTCTACCTCCTGCGCCGCCTGACCC
GCTTCGCCATGGAGGATATCAGTCTGGCGGACCCTGCCGCACTTCAAATGGCCATTGCCGCGTGGGACGCCTATGAACGC
CTGGGCTCTCCGGAAGGAGAGCTGGCGATTGCTGAACTGATTATCTACCTGGGCTGCGCCCCCAAATCCAACAGTGCCTA
CACCGCGTGGGGAGCGGCACGGAAAGCGGCACGGGAATACGGGTCCCTGATGCCCCCGGCACACATCCTCAACGCGCCCA
CCAAACTAATGAAGGAACTGGGCTATGGAAAGAATTACGCATACGATCATGACGCGCCGGACGCTTTCTCCGGGCAAAAC
TACTTTCCGGACAACATGCCCCGCCGCCAGTTCTACAGGCCGCCGGAACGGGGTTTTGAACGGGAAATCAACAAACGCCT
GGCCTATTGGGACAAACTGCGCCGCCAGCGGGCGGAAGAGGACGCCGGAAACTCCGGTACGCGCAGTAACAGAAAAAAGC
CTCCTGTTCCGGAAAAACGGGATCCCTCATGA

Upstream 100 bases:

>100_bases
CGTCAAAACCGGGGTGCAACATCCTCTCCACGAAGTGCCGTCGTGCCGGGCCGCCTGAAATGCCAGCAGGCTCCCCTTGC
CTTCCTTTTACCGGCGGCGT

Downstream 100 bases:

>100_bases
CGCATCCGCCGGCCATACGGCCACTTCCGCAATTCCCTGCCCCGGAGACAGGCGGATGCGTACGTACCTGGCGCCGGTCC
CTTCCGGACACATTGCGGTC

Product: ATPase AAA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MMGIMKKDDIPGLFSALADRPLADRLRPSALEDIMGQDHLLGEGGPLRLMADSGKMTSFILWGPPGCGKTTLARILATRT
SMHFAALSAVFSGMADLRKAFDEAARRREYGHGTLLFVDEIHRFNRAQQDGFLPYVENGTVTLVGATTENPSFELNSALL
SRCKVFVMHSLDAPALESIIERAETLLQRELPLAPEARATLIELADGDGRYLINLMESVFDLCKPDEMLGTDALLKIVQQ
RAPVYDKDREGHYNLISALHKSLRGSDTDAALYWAARMLEGGEDPLYLLRRLTRFAMEDISLADPAALQMAIAAWDAYER
LGSPEGELAIAELIIYLGCAPKSNSAYTAWGAARKAAREYGSLMPPAHILNAPTKLMKELGYGKNYAYDHDAPDAFSGQN
YFPDNMPRRQFYRPPERGFEREINKRLAYWDKLRRQRAEEDAGNSGTRSNRKKPPVPEKRDPS

Sequences:

>Translated_463_residues
MMGIMKKDDIPGLFSALADRPLADRLRPSALEDIMGQDHLLGEGGPLRLMADSGKMTSFILWGPPGCGKTTLARILATRT
SMHFAALSAVFSGMADLRKAFDEAARRREYGHGTLLFVDEIHRFNRAQQDGFLPYVENGTVTLVGATTENPSFELNSALL
SRCKVFVMHSLDAPALESIIERAETLLQRELPLAPEARATLIELADGDGRYLINLMESVFDLCKPDEMLGTDALLKIVQQ
RAPVYDKDREGHYNLISALHKSLRGSDTDAALYWAARMLEGGEDPLYLLRRLTRFAMEDISLADPAALQMAIAAWDAYER
LGSPEGELAIAELIIYLGCAPKSNSAYTAWGAARKAAREYGSLMPPAHILNAPTKLMKELGYGKNYAYDHDAPDAFSGQN
YFPDNMPRRQFYRPPERGFEREINKRLAYWDKLRRQRAEEDAGNSGTRSNRKKPPVPEKRDPS
>Mature_463_residues
MMGIMKKDDIPGLFSALADRPLADRLRPSALEDIMGQDHLLGEGGPLRLMADSGKMTSFILWGPPGCGKTTLARILATRT
SMHFAALSAVFSGMADLRKAFDEAARRREYGHGTLLFVDEIHRFNRAQQDGFLPYVENGTVTLVGATTENPSFELNSALL
SRCKVFVMHSLDAPALESIIERAETLLQRELPLAPEARATLIELADGDGRYLINLMESVFDLCKPDEMLGTDALLKIVQQ
RAPVYDKDREGHYNLISALHKSLRGSDTDAALYWAARMLEGGEDPLYLLRRLTRFAMEDISLADPAALQMAIAAWDAYER
LGSPEGELAIAELIIYLGCAPKSNSAYTAWGAARKAAREYGSLMPPAHILNAPTKLMKELGYGKNYAYDHDAPDAFSGQN
YFPDNMPRRQFYRPPERGFEREINKRLAYWDKLRRQRAEEDAGNSGTRSNRKKPPVPEKRDPS

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=441, Percent_Identity=43.0839002267574, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI18426904, Length=441, Percent_Identity=38.7755102040816, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1787119, Length=426, Percent_Identity=47.1830985915493, Blast_Score=392, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6324111, Length=421, Percent_Identity=41.8052256532066, Blast_Score=304, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6324039, Length=216, Percent_Identity=30.0925925925926, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 51614; Mature: 51614

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGIMKKDDIPGLFSALADRPLADRLRPSALEDIMGQDHLLGEGGPLRLMADSGKMTSFI
CCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHCCCCCEECCCCCEEEEECCCCEEEEE
LWGPPGCGKTTLARILATRTSMHFAALSAVFSGMADLRKAFDEAARRREYGHGTLLFVDE
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
IHRFNRAQQDGFLPYVENGTVTLVGATTENPSFELNSALLSRCKVFVMHSLDAPALESII
HHHHHHHHCCCCCCEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
ERAETLLQRELPLAPEARATLIELADGDGRYLINLMESVFDLCKPDEMLGTDALLKIVQQ
HHHHHHHHHCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHH
RAPVYDKDREGHYNLISALHKSLRGSDTDAALYWAARMLEGGEDPLYLLRRLTRFAMEDI
HCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
SLADPAALQMAIAAWDAYERLGSPEGELAIAELIIYLGCAPKSNSAYTAWGAARKAAREY
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHH
GSLMPPAHILNAPTKLMKELGYGKNYAYDHDAPDAFSGQNYFPDNMPRRQFYRPPERGFE
CCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHH
REINKRLAYWDKLRRQRAEEDAGNSGTRSNRKKPPVPEKRDPS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMGIMKKDDIPGLFSALADRPLADRLRPSALEDIMGQDHLLGEGGPLRLMADSGKMTSFI
CCCCCCCCCCCHHHHHHHCCCCHHHCCHHHHHHHCCCCCEECCCCCEEEEECCCCEEEEE
LWGPPGCGKTTLARILATRTSMHFAALSAVFSGMADLRKAFDEAARRREYGHGTLLFVDE
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
IHRFNRAQQDGFLPYVENGTVTLVGATTENPSFELNSALLSRCKVFVMHSLDAPALESII
HHHHHHHHCCCCCCEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
ERAETLLQRELPLAPEARATLIELADGDGRYLINLMESVFDLCKPDEMLGTDALLKIVQQ
HHHHHHHHHCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHH
RAPVYDKDREGHYNLISALHKSLRGSDTDAALYWAARMLEGGEDPLYLLRRLTRFAMEDI
HCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
SLADPAALQMAIAAWDAYERLGSPEGELAIAELIIYLGCAPKSNSAYTAWGAARKAAREY
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHH
GSLMPPAHILNAPTKLMKELGYGKNYAYDHDAPDAFSGQNYFPDNMPRRQFYRPPERGFE
CCCCCCHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHH
REINKRLAYWDKLRRQRAEEDAGNSGTRSNRKKPPVPEKRDPS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]