Click here to switch to the map view.

The map label for this gene is lacZ [H]

Identifier: 187736153

GI number: 187736153

Start: 2013730

End: 2017599

Strand: Direct

Name: lacZ [H]

Synonym: Amuc_1666

Alternate gene names: 187736153

Gene position: 2013730-2017599 (Clockwise)

Preceding gene: 187736151

Following gene: 187736154

Centisome position: 75.59

GC content: 56.54

Gene sequence:

>3870_bases
ATGAAGACGGTACGCGCGTTTCTGTTTTCCGTGATGTGTCTGGCTCCGGCTCTTCCCCTGCTGGGGGATGTTCCGGATTG
GGAAAATGAAGAGGTGACGGGAATCAATAAGGAGGCTCCCCGAGCCTCCGTTTTTCCGGCATCGGATAAAACGTTGAGCT
TGAACGGGGATTGGAAGTTCAAATTTTCCATGACTCCGGACGAGAGGCCTGCCGATTTCTTCAATCCCTCTTATTCCGTT
TCCGGATGGGATACGGTCAAGGTTCCTTCCAACTGGCAGCTTTACGGTTATGGAACGGCCATTTACACGAATGTTCCCTA
TCCATTCAAGCCGAATCCTCCCAAGGTAATGGGGGAACCGCCCAAGAACTGGCCGGCGTACAGGGAGCGTAATTCCGTGG
GTTCCTACCGCCGGGATTTCAATTTGCCCGTTTCCTGGAAGGGAGAGCAGGTGATGATCCGGTTTGACGGGGTGGAGTCC
GCCTTTTATGTGTGGGTAAATGGCCGTCAAGTCGGCTATTCCGAAGATTCCTATACAGGGGCGGAGTTTGACCTTACTCC
CTATGTCAGGCCCGGCAGGAATACGATTGCCGTGGAAGTATACCGCTGGAGCGACGGTTCTTACCTGGAGGACCAGGATT
TCCTGCGCCTTTCCGGCATTTTCCGGGACGTGACCCTGTTTGCCCAGCCGCAGACGCACGTGCGTGACCTGTTCCTGAAG
GCCGGACTGGACAGGGAGGATTACACAACCGGGGTACTGGACGGAACGTTCACCATCCGCAATTCCGGTAAAAAGGATAT
TCCCGCCGGCATGAAGCTGAATTATTCCATCGACGGGATTTCCACCAAATTGAACTGGGAGGGCAGGAACGGTTCCGGCC
GCGTGCAGACGGACAACAGGGGAAGGCTGGATTCCGGAACGCTGGAGGTTCCCTCCATTCCCTCCGGAGGCGAGGTGCAG
ATTTCCCTGAACAGGAAATTTCCCGGTGTGAAGCCATGGACGGCGGAAACGCCCAACCTGTACAGGGTGACTTATTCTCT
GAATGGAAAGGATACCCGTTCCGTCAATATCGGGTTCCGTTCCGTGGAGATTGCGGATAACGGCGCCGTGCTGATTAACG
GCAGAGCCGTCAAGTTCAAGGGTGTCAACCGCCATGAAGCCCATCCCGATTACGGGCGCGCCATTCCGCGGGAAGTGATG
GAAAAGGACGTGCAGATTATCAAGGCGCATAATATCAATACCGTCCGTTGTTCCCACTATCCCAATCATCCTTATTTTTA
TGAGTTGTGCGACCGCTACGGCCTGTACGTGATGGACGAAGCCAACTGCGAAGCCCACGGCATCCGCAATAGCAGCATGG
ATATTTCCCGGAAGCCTTCCTGGAAGAAAGCCCATGTGGAGCGCAATATGAGCATGGTGCATCGTTCCAAGAACCACCCT
TCCATTGTTTTCTGGTCCCTGGGCAATGAGTCCGGAAACGGTCCCAATTTTGAGGCGGCAGCGGCGGCTGTCAGGGCTTA
TGACACTACGCGGCCCCTCCATTACTGCGAATTTCCGCACGGCCACAAGGCCGTGGATATGGATTCCGCCATGTATCCGC
CCGTGGACCGGGTGGAAAACTGGGGGAAGCAGAAAACTTCCCGCCCCTTTTTCGTGTGCGAATATGCCCACTCCATGGGG
AATGCCCTGGGGAATTTCAAGGAGTACATGGATGCCTTCGAGTCTTCCCCGCGCATGGTGGGCGGGGCCATCTGGGATTT
CGTGGACCAGTCCCTCCGCGCCAATCCTGCCGGAAACGGCATTTACAAGCCCGCCCCTTTCAAGGGAGTAACACAGGCTT
ACGGCGGCATGTTCGGAGACAGGCCCAACCAGGCCAATTTCTGCGACAACGGCATTATTCTTGGCAACCGGAACACCACG
GCCAAGACGAAAGAGGTGAAGAAAGTATACCAGTACATGGCTTTTGAGCGCAAGGACGGGTCCCTGTCCGTTCGCAACAA
ATATTTCCATAAGCCTTTGAAAGGTTATACGCTTTATCTGGTATCCCTTGTTCCCGGCGGCGGCCATGCCGTGGAGCGCA
TGGTTCTGCCGGAGGTTCCCCCCGGCAAATCCGCAACGGTTAATCTGCCTTCAGCCGCTATGCGGACCGGTTCCCTGATG
GTTCTGGCGGATGCCCGGTTCAAGCTCCCGGAAGACGTGAAGGAACTTTCCTCCAAGCAACTGGAACATGTGGTGAATGA
GTGCGAAGCTTACGAGTGGTTCCCGGCATCTGCAGAGAAGGAGGTTCCCGTGCCTCCCCCGGCGGCGCTGCCTGCTGTTT
CCGTGCTCCAGGGGGATTCCGTGGCCGTGCAGGGAAAAGGTTTTTCCGCCTCCTTCAAAAACGGGATGCTTTCCTCCCTC
CGGTATGGCGGTCGGGATTTGATTTTGCCCGGCTATCCGGTGGAGCTCCAGGCGTACCGTTCTCCGGTGGATAACGATGC
CTGGATCAGGAGCAAGGTTGAAGGGAAAATGAAGATGCAGAATATGAAAGCGGAATATTCCGACGTTAAAGCTGCCGTCA
TTTCCCCCGGCGTGGCCCGAATCACGGCACAGTTCCGGACGAAAGGTTCCGAGCTTGCCTTTTCCGGGGAAGTCGCGTGG
ACGGTTTTCGGCAACGGCATTATCAATGCTTCCGTCCGAATGTATCCCTCCGCCAAGGGAGAAGAACTCCTTCGGCTGGG
CGTCACTTTCGGGATGCCTGCCGCGTATGACCGGGTAGAGTACCTGGGGCTGGGACCGTGGGATAATTACCGGGACCGCC
GCACGAGCTGCTGGAAGGACATTTTCCGCACTTCCGTGGACGATATGTTTTTTGCTTATTCCCGGCCCCAGGATATGGGC
AACCGCATGGAAACGGACTGGATAGCCTTGTCCAAACCCCAGGAGGACCAGGCTCTGTGGGTGGGGGCCGCCTCTCCCAG
GGCTCCGCTGGAGGTTTCCGTCCTGCGTTATACGCCGAAGGAGCTTAACGATGCCAGGAGCCTGGACAGGCTGCCGGAGA
AAAATAAAGTGATTGTGAATCTGGACGCTTTCCAGATGGGGCTGGGCGGCTCTTCCTGCGGGCCCCGTCCGCTGGTCAAG
TACCAGACATTGAGCGGGGCCACAGCCCTGGGGTTTGTGCTGGCTCCCTCATCCGCCCTGCTGAATCTGGCGCGCACGGG
GCTGGCCGTTCCCCATTCCCCTGTCATTGAACGGGATGGGGACGGCATGGTCAGTCTGACTTCCTCTACGCCCGAGGCGG
AGATAAAGTATTCCGTCAACAAGGGGCCGGAAAAAACGTACCGGAATCCCTTCAAGCTTCCCGAAGGGGAAGTTAGGGCC
TGGGCTGCCTCCATGAAGTCCGGCAAGGTTCCTTCCACGTCTCCCGGAGAGAGGAAATTCCCCCTCGTCAAGGGGCAGGG
CGAATGGAAAATTCTAAGCGCTTCTTCGGAAGAGCCGGATACCGGTTTCGCCCATTTTGCCATTGACGGGAATCCGGATA
CCTATTGGCATACGTCCTATACGAACGGCCTGCCGGGGTTCCCCCACTCCATTGCCGTGGATATGGGAACCAGAATGAAG
TTTACCGGATTTATCTACACGCCCAGAATGGACAAGGACAAGGGCCTCATCAGCCAGTACACGTTTTCCGTTTCCGATGA
CGGTCGGAATTGGAGGGAAGTGAAAAAAGGCCAGTTCTCCTACCACTATATCCGGAAGGATCCGGCTGTTCAGCGCATCG
ACTTCGGCAGGCCTGTGGAGGCCCGCTACTTTAAGCTTGACGCCCGGTCTCCGGTGAGGGGCGGGGAACAGAGCGCCACC
GTTGCGGAGCTGAATATCATTACCCAATAA

Upstream 100 bases:

>100_bases
ACGTTGAACCCTGCCGGAGGTGACGGGAAGAAGGATTCAGAGCGTTATCAGGATCCGTCCCTGAAAAAGTATAAGTAAGC
AATTCCATATTCATTCCGAG

Downstream 100 bases:

>100_bases
CGGAGCGGCAGGCGTTTTGCACTGCTTCCCGGATGGAGAAGTTTTCCAGCCGTGCGCCCTTTCCGGGGTGCACGGCTTGT
TGTTGCGGGCTTTTCAGGGT

Product: glycoside hydrolase family 2 TIM barrel

Products: NA

Alternate protein names: Beta-gal; Lactase [H]

Number of amino acids: Translated: 1289; Mature: 1289

Protein sequence:

>1289_residues
MKTVRAFLFSVMCLAPALPLLGDVPDWENEEVTGINKEAPRASVFPASDKTLSLNGDWKFKFSMTPDERPADFFNPSYSV
SGWDTVKVPSNWQLYGYGTAIYTNVPYPFKPNPPKVMGEPPKNWPAYRERNSVGSYRRDFNLPVSWKGEQVMIRFDGVES
AFYVWVNGRQVGYSEDSYTGAEFDLTPYVRPGRNTIAVEVYRWSDGSYLEDQDFLRLSGIFRDVTLFAQPQTHVRDLFLK
AGLDREDYTTGVLDGTFTIRNSGKKDIPAGMKLNYSIDGISTKLNWEGRNGSGRVQTDNRGRLDSGTLEVPSIPSGGEVQ
ISLNRKFPGVKPWTAETPNLYRVTYSLNGKDTRSVNIGFRSVEIADNGAVLINGRAVKFKGVNRHEAHPDYGRAIPREVM
EKDVQIIKAHNINTVRCSHYPNHPYFYELCDRYGLYVMDEANCEAHGIRNSSMDISRKPSWKKAHVERNMSMVHRSKNHP
SIVFWSLGNESGNGPNFEAAAAAVRAYDTTRPLHYCEFPHGHKAVDMDSAMYPPVDRVENWGKQKTSRPFFVCEYAHSMG
NALGNFKEYMDAFESSPRMVGGAIWDFVDQSLRANPAGNGIYKPAPFKGVTQAYGGMFGDRPNQANFCDNGIILGNRNTT
AKTKEVKKVYQYMAFERKDGSLSVRNKYFHKPLKGYTLYLVSLVPGGGHAVERMVLPEVPPGKSATVNLPSAAMRTGSLM
VLADARFKLPEDVKELSSKQLEHVVNECEAYEWFPASAEKEVPVPPPAALPAVSVLQGDSVAVQGKGFSASFKNGMLSSL
RYGGRDLILPGYPVELQAYRSPVDNDAWIRSKVEGKMKMQNMKAEYSDVKAAVISPGVARITAQFRTKGSELAFSGEVAW
TVFGNGIINASVRMYPSAKGEELLRLGVTFGMPAAYDRVEYLGLGPWDNYRDRRTSCWKDIFRTSVDDMFFAYSRPQDMG
NRMETDWIALSKPQEDQALWVGAASPRAPLEVSVLRYTPKELNDARSLDRLPEKNKVIVNLDAFQMGLGGSSCGPRPLVK
YQTLSGATALGFVLAPSSALLNLARTGLAVPHSPVIERDGDGMVSLTSSTPEAEIKYSVNKGPEKTYRNPFKLPEGEVRA
WAASMKSGKVPSTSPGERKFPLVKGQGEWKILSASSEEPDTGFAHFAIDGNPDTYWHTSYTNGLPGFPHSIAVDMGTRMK
FTGFIYTPRMDKDKGLISQYTFSVSDDGRNWREVKKGQFSYHYIRKDPAVQRIDFGRPVEARYFKLDARSPVRGGEQSAT
VAELNIITQ

Sequences:

>Translated_1289_residues
MKTVRAFLFSVMCLAPALPLLGDVPDWENEEVTGINKEAPRASVFPASDKTLSLNGDWKFKFSMTPDERPADFFNPSYSV
SGWDTVKVPSNWQLYGYGTAIYTNVPYPFKPNPPKVMGEPPKNWPAYRERNSVGSYRRDFNLPVSWKGEQVMIRFDGVES
AFYVWVNGRQVGYSEDSYTGAEFDLTPYVRPGRNTIAVEVYRWSDGSYLEDQDFLRLSGIFRDVTLFAQPQTHVRDLFLK
AGLDREDYTTGVLDGTFTIRNSGKKDIPAGMKLNYSIDGISTKLNWEGRNGSGRVQTDNRGRLDSGTLEVPSIPSGGEVQ
ISLNRKFPGVKPWTAETPNLYRVTYSLNGKDTRSVNIGFRSVEIADNGAVLINGRAVKFKGVNRHEAHPDYGRAIPREVM
EKDVQIIKAHNINTVRCSHYPNHPYFYELCDRYGLYVMDEANCEAHGIRNSSMDISRKPSWKKAHVERNMSMVHRSKNHP
SIVFWSLGNESGNGPNFEAAAAAVRAYDTTRPLHYCEFPHGHKAVDMDSAMYPPVDRVENWGKQKTSRPFFVCEYAHSMG
NALGNFKEYMDAFESSPRMVGGAIWDFVDQSLRANPAGNGIYKPAPFKGVTQAYGGMFGDRPNQANFCDNGIILGNRNTT
AKTKEVKKVYQYMAFERKDGSLSVRNKYFHKPLKGYTLYLVSLVPGGGHAVERMVLPEVPPGKSATVNLPSAAMRTGSLM
VLADARFKLPEDVKELSSKQLEHVVNECEAYEWFPASAEKEVPVPPPAALPAVSVLQGDSVAVQGKGFSASFKNGMLSSL
RYGGRDLILPGYPVELQAYRSPVDNDAWIRSKVEGKMKMQNMKAEYSDVKAAVISPGVARITAQFRTKGSELAFSGEVAW
TVFGNGIINASVRMYPSAKGEELLRLGVTFGMPAAYDRVEYLGLGPWDNYRDRRTSCWKDIFRTSVDDMFFAYSRPQDMG
NRMETDWIALSKPQEDQALWVGAASPRAPLEVSVLRYTPKELNDARSLDRLPEKNKVIVNLDAFQMGLGGSSCGPRPLVK
YQTLSGATALGFVLAPSSALLNLARTGLAVPHSPVIERDGDGMVSLTSSTPEAEIKYSVNKGPEKTYRNPFKLPEGEVRA
WAASMKSGKVPSTSPGERKFPLVKGQGEWKILSASSEEPDTGFAHFAIDGNPDTYWHTSYTNGLPGFPHSIAVDMGTRMK
FTGFIYTPRMDKDKGLISQYTFSVSDDGRNWREVKKGQFSYHYIRKDPAVQRIDFGRPVEARYFKLDARSPVRGGEQSAT
VAELNIITQ
>Mature_1289_residues
MKTVRAFLFSVMCLAPALPLLGDVPDWENEEVTGINKEAPRASVFPASDKTLSLNGDWKFKFSMTPDERPADFFNPSYSV
SGWDTVKVPSNWQLYGYGTAIYTNVPYPFKPNPPKVMGEPPKNWPAYRERNSVGSYRRDFNLPVSWKGEQVMIRFDGVES
AFYVWVNGRQVGYSEDSYTGAEFDLTPYVRPGRNTIAVEVYRWSDGSYLEDQDFLRLSGIFRDVTLFAQPQTHVRDLFLK
AGLDREDYTTGVLDGTFTIRNSGKKDIPAGMKLNYSIDGISTKLNWEGRNGSGRVQTDNRGRLDSGTLEVPSIPSGGEVQ
ISLNRKFPGVKPWTAETPNLYRVTYSLNGKDTRSVNIGFRSVEIADNGAVLINGRAVKFKGVNRHEAHPDYGRAIPREVM
EKDVQIIKAHNINTVRCSHYPNHPYFYELCDRYGLYVMDEANCEAHGIRNSSMDISRKPSWKKAHVERNMSMVHRSKNHP
SIVFWSLGNESGNGPNFEAAAAAVRAYDTTRPLHYCEFPHGHKAVDMDSAMYPPVDRVENWGKQKTSRPFFVCEYAHSMG
NALGNFKEYMDAFESSPRMVGGAIWDFVDQSLRANPAGNGIYKPAPFKGVTQAYGGMFGDRPNQANFCDNGIILGNRNTT
AKTKEVKKVYQYMAFERKDGSLSVRNKYFHKPLKGYTLYLVSLVPGGGHAVERMVLPEVPPGKSATVNLPSAAMRTGSLM
VLADARFKLPEDVKELSSKQLEHVVNECEAYEWFPASAEKEVPVPPPAALPAVSVLQGDSVAVQGKGFSASFKNGMLSSL
RYGGRDLILPGYPVELQAYRSPVDNDAWIRSKVEGKMKMQNMKAEYSDVKAAVISPGVARITAQFRTKGSELAFSGEVAW
TVFGNGIINASVRMYPSAKGEELLRLGVTFGMPAAYDRVEYLGLGPWDNYRDRRTSCWKDIFRTSVDDMFFAYSRPQDMG
NRMETDWIALSKPQEDQALWVGAASPRAPLEVSVLRYTPKELNDARSLDRLPEKNKVIVNLDAFQMGLGGSSCGPRPLVK
YQTLSGATALGFVLAPSSALLNLARTGLAVPHSPVIERDGDGMVSLTSSTPEAEIKYSVNKGPEKTYRNPFKLPEGEVRA
WAASMKSGKVPSTSPGERKFPLVKGQGEWKILSASSEEPDTGFAHFAIDGNPDTYWHTSYTNGLPGFPHSIAVDMGTRMK
FTGFIYTPRMDKDKGLISQYTFSVSDDGRNWREVKKGQFSYHYIRKDPAVQRIDFGRPVEARYFKLDARSPVRGGEQSAT
VAELNIITQ

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=438, Percent_Identity=24.2009132420091, Blast_Score=109, Evalue=2e-23,
Organism=Escherichia coli, GI1786539, Length=1076, Percent_Identity=32.3420074349442, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI48994920, Length=1070, Percent_Identity=31.588785046729, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1787903, Length=583, Percent_Identity=24.3567753001715, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19922582, Length=525, Percent_Identity=25.9047619047619, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI62471735, Length=525, Percent_Identity=25.9047619047619, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24655438, Length=525, Percent_Identity=25.9047619047619, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24651745, Length=432, Percent_Identity=26.8518518518519, Blast_Score=111, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR011013
- InterPro:   IPR014718
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR004199
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF02929 Bgal_small_N; PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 143678; Mature: 143678

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50022 FA58C_3 ; PS00719 GLYCOSYL_HYDROL_F2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVRAFLFSVMCLAPALPLLGDVPDWENEEVTGINKEAPRASVFPASDKTLSLNGDWKF
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE
KFSMTPDERPADFFNPSYSVSGWDTVKVPSNWQLYGYGTAIYTNVPYPFKPNPPKVMGEP
EEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECEEEEECCCCCCCCCCCCCCCCC
PKNWPAYRERNSVGSYRRDFNLPVSWKGEQVMIRFDGVESAFYVWVNGRQVGYSEDSYTG
CCCCCCHHHHCCCCCHHHCCCCCEECCCCEEEEEEECCCEEEEEEECCEEECCCCCCCCC
AEFDLTPYVRPGRNTIAVEVYRWSDGSYLEDQDFLRLSGIFRDVTLFAQPQTHVRDLFLK
CEEECCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHEEEEEECCHHHHHHHHHH
AGLDREDYTTGVLDGTFTIRNSGKKDIPAGMKLNYSIDGISTKLNWEGRNGSGRVQTDNR
CCCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECCC
GRLDSGTLEVPSIPSGGEVQISLNRKFPGVKPWTAETPNLYRVTYSLNGKDTRSVNIGFR
CCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECEE
SVEIADNGAVLINGRAVKFKGVNRHEAHPDYGRAIPREVMEKDVQIIKAHNINTVRCSHY
EEEEECCCEEEECCEEEEEECCCCCCCCCCHHHCCHHHHHHHHHEEEEECCCCEEEECCC
PNHPYFYELCDRYGLYVMDEANCEAHGIRNSSMDISRKPSWKKAHVERNMSMVHRSKNHP
CCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
SIVFWSLGNESGNGPNFEAAAAAVRAYDTTRPLHYCEFPHGHKAVDMDSAMYPPVDRVEN
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEECCCCCCCCCHHHHHH
WGKQKTSRPFFVCEYAHSMGNALGNFKEYMDAFESSPRMVGGAIWDFVDQSLRANPAGNG
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
IYKPAPFKGVTQAYGGMFGDRPNQANFCDNGIILGNRNTTAKTKEVKKVYQYMAFERKDG
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHEECCCC
SLSVRNKYFHKPLKGYTLYLVSLVPGGGHAVERMVLPEVPPGKSATVNLPSAAMRTGSLM
CEEECHHHHCCCCCCEEEEEEEEECCCCHHHHHEECCCCCCCCCEEEECCHHHHCCCCEE
VLADARFKLPEDVKELSSKQLEHVVNECEAYEWFPASAEKEVPVPPPAALPAVSVLQGDS
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCHHEECCCC
VAVQGKGFSASFKNGMLSSLRYGGRDLILPGYPVELQAYRSPVDNDAWIRSKVEGKMKMQ
EEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCEEHHHHCCCCCCCHHHHHHHCCHHHHH
NMKAEYSDVKAAVISPGVARITAQFRTKGSELAFSGEVAWTVFGNGIINASVRMYPSAKG
HHHHHHHHCEEEEECCCHHEEEEHHHCCCCCEEECCCEEEEEECCCEEEEEEEECCCCCC
EELLRLGVTFGMPAAYDRVEYLGLGPWDNYRDRRTSCWKDIFRTSVDDMFFAYSRPQDMG
CCEEEEHHHCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHEEECCCHHHC
NRMETDWIALSKPQEDQALWVGAASPRAPLEVSVLRYTPKELNDARSLDRLPEKNKVIVN
CCCCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEE
LDAFQMGLGGSSCGPRPLVKYQTLSGATALGFVLAPSSALLNLARTGLAVPHSPVIERDG
ECCEEECCCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCEECCC
DGMVSLTSSTPEAEIKYSVNKGPEKTYRNPFKLPEGEVRAWAASMKSGKVPSTSPGERKF
CCEEEEECCCCCCEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
PLVKGQGEWKILSASSEEPDTGFAHFAIDGNPDTYWHTSYTNGLPGFPHSIAVDMGTRMK
CEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEECCCCEE
FTGFIYTPRMDKDKGLISQYTFSVSDDGRNWREVKKGQFSYHYIRKDPAVQRIDFGRPVE
EEEEEECCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEECCCCCEEECCCCCCC
ARYFKLDARSPVRGGEQSATVAELNIITQ
EEEEEEECCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MKTVRAFLFSVMCLAPALPLLGDVPDWENEEVTGINKEAPRASVFPASDKTLSLNGDWKF
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEE
KFSMTPDERPADFFNPSYSVSGWDTVKVPSNWQLYGYGTAIYTNVPYPFKPNPPKVMGEP
EEECCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECEEEEECCCCCCCCCCCCCCCCC
PKNWPAYRERNSVGSYRRDFNLPVSWKGEQVMIRFDGVESAFYVWVNGRQVGYSEDSYTG
CCCCCCHHHHCCCCCHHHCCCCCEECCCCEEEEEEECCCEEEEEEECCEEECCCCCCCCC
AEFDLTPYVRPGRNTIAVEVYRWSDGSYLEDQDFLRLSGIFRDVTLFAQPQTHVRDLFLK
CEEECCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHEEEEEECCHHHHHHHHHH
AGLDREDYTTGVLDGTFTIRNSGKKDIPAGMKLNYSIDGISTKLNWEGRNGSGRVQTDNR
CCCCCCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECCC
GRLDSGTLEVPSIPSGGEVQISLNRKFPGVKPWTAETPNLYRVTYSLNGKDTRSVNIGFR
CCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECEE
SVEIADNGAVLINGRAVKFKGVNRHEAHPDYGRAIPREVMEKDVQIIKAHNINTVRCSHY
EEEEECCCEEEECCEEEEEECCCCCCCCCCHHHCCHHHHHHHHHEEEEECCCCEEEECCC
PNHPYFYELCDRYGLYVMDEANCEAHGIRNSSMDISRKPSWKKAHVERNMSMVHRSKNHP
CCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
SIVFWSLGNESGNGPNFEAAAAAVRAYDTTRPLHYCEFPHGHKAVDMDSAMYPPVDRVEN
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEECCCCCCCCCHHHHHH
WGKQKTSRPFFVCEYAHSMGNALGNFKEYMDAFESSPRMVGGAIWDFVDQSLRANPAGNG
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
IYKPAPFKGVTQAYGGMFGDRPNQANFCDNGIILGNRNTTAKTKEVKKVYQYMAFERKDG
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHEECCCC
SLSVRNKYFHKPLKGYTLYLVSLVPGGGHAVERMVLPEVPPGKSATVNLPSAAMRTGSLM
CEEECHHHHCCCCCCEEEEEEEEECCCCHHHHHEECCCCCCCCCEEEECCHHHHCCCCEE
VLADARFKLPEDVKELSSKQLEHVVNECEAYEWFPASAEKEVPVPPPAALPAVSVLQGDS
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCHHEECCCC
VAVQGKGFSASFKNGMLSSLRYGGRDLILPGYPVELQAYRSPVDNDAWIRSKVEGKMKMQ
EEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCEEHHHHCCCCCCCHHHHHHHCCHHHHH
NMKAEYSDVKAAVISPGVARITAQFRTKGSELAFSGEVAWTVFGNGIINASVRMYPSAKG
HHHHHHHHCEEEEECCCHHEEEEHHHCCCCCEEECCCEEEEEECCCEEEEEEEECCCCCC
EELLRLGVTFGMPAAYDRVEYLGLGPWDNYRDRRTSCWKDIFRTSVDDMFFAYSRPQDMG
CCEEEEHHHCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHEEECCCHHHC
NRMETDWIALSKPQEDQALWVGAASPRAPLEVSVLRYTPKELNDARSLDRLPEKNKVIVN
CCCCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEE
LDAFQMGLGGSSCGPRPLVKYQTLSGATALGFVLAPSSALLNLARTGLAVPHSPVIERDG
ECCEEECCCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCEECCC
DGMVSLTSSTPEAEIKYSVNKGPEKTYRNPFKLPEGEVRAWAASMKSGKVPSTSPGERKF
CCEEEEECCCCCCEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
PLVKGQGEWKILSASSEEPDTGFAHFAIDGNPDTYWHTSYTNGLPGFPHSIAVDMGTRMK
CEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCEEEEECCCCEE
FTGFIYTPRMDKDKGLISQYTFSVSDDGRNWREVKKGQFSYHYIRKDPAVQRIDFGRPVE
EEEEEECCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEECCCCCEEECCCCCCC
ARYFKLDARSPVRGGEQSATVAELNIITQ
EEEEEEECCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8088532; 10360571; 9741105 [H]