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The map label for this gene is nuoH [H]

Identifier: 187736099

GI number: 187736099

Start: 1934611

End: 1935879

Strand: Reverse

Name: nuoH [H]

Synonym: Amuc_1610

Alternate gene names: 187736099

Gene position: 1935879-1934611 (Counterclockwise)

Preceding gene: 187736100

Following gene: 187736098

Centisome position: 72.67

GC content: 56.9

Gene sequence:

>1269_bases
ATGATTGATTCGATTCTAACCTTTTGCGACGAGGTGCTCAGCAACCCTGTGTGGTTTTATATCATCACTCTGCTGATCAA
AATCGTCATCTGCTTTGCCATCACCATTCTGTTCATTCCGGTCTGCGTGTACATTGAACGCCGGGTGGCCGCCTGGATCC
AGGACCGCGTAGGCCCCAACCGCGCCGGCATTCCGTTAAGCATCTTCCGCCGCTTCGGCATGAAATCCGACCTGCCGTTC
AAAAAGACGCTGGACTACTTCGGGTTGCCCCATGACGGCAAAATCGCCAACCTGTGCCGTTTTTTCCGCCTGGACCGCGA
CATCCCCATCTTCGGTCTCGTGCAGCCCATGGTGGACGGCGGCAAACTGTTCCTGAAACAGGATTTCACGCCCCCCTTCG
TACGCCGCGTATACTTCTGGATCGCTCCCATCCTGGTGCTTGCGCCACCGCTGATGACGGCGGCCGTGGTTCCCTTCGCC
GGAGACCTTCAAACCTCTTACGGAAACGTCAACATGGCGGTGGCCAACCTCAGCGTAGGCCCCCTCTGGATGTTCGCCAT
CTCCTCCCTCTCCGTGTACGGACTGGTGCTGGCCGGATGGTCATCCAACTCCAAATTCCCCTTCCTGGGCGGCGTGCGCT
CCTCAGCCCAGATGATTTCCTATGAAATCAGCATGGGTCTGTCCATCATCCCTGTGCTGATGATTTACAGCACGCTGGAC
CTGTCCAACATCGTGGAATACCAGGCCGCCAACGGCTGGCTCCTGCTTCCCGTGTGGGGCGAGGGCCTGAGCTGGCAGCG
CTGGATACTGCTGGTGCCCGTAGCTATCAGTTTCATCATATTCCTCACCTCCATTTTTGCGGAAGCCAACCGTACGCCGT
TTGACATGTCCGAATGTGAAACGGACCTCGTGGGCGGCTACCATACGGAATACTCCTCCATGAAATTCGCCCAATTCTTC
ATGGGGGAATATGCCGCCATGGTGGTGGGATCCTCCCTTGTCATCACGCTGTTCCTGGGGGGCTGGTCCATCGGCTTCGG
CCTGGACGGCTGGCTCAATGAAAACGTAGCCAACTGGGTGGCGGTCATCTGCCAGCTCATCGCATATGTGCTCAAGCTTC
TCTTCTTCGCCTTCTTCTTCGTCTGGGTGCGGTGGACGCTCCCCCGCTTCCGCTATGACCAGGTGATGAAGCTCGGCTGG
ATGGTCTTCTTTGAACTGGCCGTCATCAACATCTTCCTTACAGCCGCCATCCTGTACTTCGTCAAGTAA

Upstream 100 bases:

>100_bases
AGCCCATTCTGGAAACCGGCGTCACCATTCCCGTGGTGGAACGCGAAAAAAACCAGGGCCGCTAATCACACTTCACACGC
ATACAACCTGTTAATCCGCC

Downstream 100 bases:

>100_bases
TCCCCCCCTTCTTCATTCCGACAACATTACTATTATGGCCTTCAAAACGATCAAGCGTCCGAAGATTTCCCTTGGAGAGC
GGTTCTATCTGCAATCCATT

Product: NADH dehydrogenase (quinone)

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MIDSILTFCDEVLSNPVWFYIITLLIKIVICFAITILFIPVCVYIERRVAAWIQDRVGPNRAGIPLSIFRRFGMKSDLPF
KKTLDYFGLPHDGKIANLCRFFRLDRDIPIFGLVQPMVDGGKLFLKQDFTPPFVRRVYFWIAPILVLAPPLMTAAVVPFA
GDLQTSYGNVNMAVANLSVGPLWMFAISSLSVYGLVLAGWSSNSKFPFLGGVRSSAQMISYEISMGLSIIPVLMIYSTLD
LSNIVEYQAANGWLLLPVWGEGLSWQRWILLVPVAISFIIFLTSIFAEANRTPFDMSECETDLVGGYHTEYSSMKFAQFF
MGEYAAMVVGSSLVITLFLGGWSIGFGLDGWLNENVANWVAVICQLIAYVLKLLFFAFFFVWVRWTLPRFRYDQVMKLGW
MVFFELAVINIFLTAAILYFVK

Sequences:

>Translated_422_residues
MIDSILTFCDEVLSNPVWFYIITLLIKIVICFAITILFIPVCVYIERRVAAWIQDRVGPNRAGIPLSIFRRFGMKSDLPF
KKTLDYFGLPHDGKIANLCRFFRLDRDIPIFGLVQPMVDGGKLFLKQDFTPPFVRRVYFWIAPILVLAPPLMTAAVVPFA
GDLQTSYGNVNMAVANLSVGPLWMFAISSLSVYGLVLAGWSSNSKFPFLGGVRSSAQMISYEISMGLSIIPVLMIYSTLD
LSNIVEYQAANGWLLLPVWGEGLSWQRWILLVPVAISFIIFLTSIFAEANRTPFDMSECETDLVGGYHTEYSSMKFAQFF
MGEYAAMVVGSSLVITLFLGGWSIGFGLDGWLNENVANWVAVICQLIAYVLKLLFFAFFFVWVRWTLPRFRYDQVMKLGW
MVFFELAVINIFLTAAILYFVK
>Mature_422_residues
MIDSILTFCDEVLSNPVWFYIITLLIKIVICFAITILFIPVCVYIERRVAAWIQDRVGPNRAGIPLSIFRRFGMKSDLPF
KKTLDYFGLPHDGKIANLCRFFRLDRDIPIFGLVQPMVDGGKLFLKQDFTPPFVRRVYFWIAPILVLAPPLMTAAVVPFA
GDLQTSYGNVNMAVANLSVGPLWMFAISSLSVYGLVLAGWSSNSKFPFLGGVRSSAQMISYEISMGLSIIPVLMIYSTLD
LSNIVEYQAANGWLLLPVWGEGLSWQRWILLVPVAISFIIFLTSIFAEANRTPFDMSECETDLVGGYHTEYSSMKFAQFF
MGEYAAMVVGSSLVITLFLGGWSIGFGLDGWLNENVANWVAVICQLIAYVLKLLFFAFFFVWVRWTLPRFRYDQVMKLGW
MVFFELAVINIFLTAAILYFVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=300, Percent_Identity=31.6666666666667, Blast_Score=145, Evalue=9e-35,
Organism=Escherichia coli, GI1788618, Length=404, Percent_Identity=31.9306930693069, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47781; Mature: 47781

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSILTFCDEVLSNPVWFYIITLLIKIVICFAITILFIPVCVYIERRVAAWIQDRVGPN
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RAGIPLSIFRRFGMKSDLPFKKTLDYFGLPHDGKIANLCRFFRLDRDIPIFGLVQPMVDG
CCCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCC
GKLFLKQDFTPPFVRRVYFWIAPILVLAPPLMTAAVVPFAGDLQTSYGNVNMAVANLSVG
CEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCC
PLWMFAISSLSVYGLVLAGWSSNSKFPFLGGVRSSAQMISYEISMGLSIIPVLMIYSTLD
HHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHC
LSNIVEYQAANGWLLLPVWGEGLSWQRWILLVPVAISFIIFLTSIFAEANRTPFDMSECE
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
TDLVGGYHTEYSSMKFAQFFMGEYAAMVVGSSLVITLFLGGWSIGFGLDGWLNENVANWV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCCCCHHCCHHHHHH
AVICQLIAYVLKLLFFAFFFVWVRWTLPRFRYDQVMKLGWMVFFELAVINIFLTAAILYF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VK
CC
>Mature Secondary Structure
MIDSILTFCDEVLSNPVWFYIITLLIKIVICFAITILFIPVCVYIERRVAAWIQDRVGPN
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RAGIPLSIFRRFGMKSDLPFKKTLDYFGLPHDGKIANLCRFFRLDRDIPIFGLVQPMVDG
CCCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCC
GKLFLKQDFTPPFVRRVYFWIAPILVLAPPLMTAAVVPFAGDLQTSYGNVNMAVANLSVG
CEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCEEEEEEECCCC
PLWMFAISSLSVYGLVLAGWSSNSKFPFLGGVRSSAQMISYEISMGLSIIPVLMIYSTLD
HHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHC
LSNIVEYQAANGWLLLPVWGEGLSWQRWILLVPVAISFIIFLTSIFAEANRTPFDMSECE
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
TDLVGGYHTEYSSMKFAQFFMGEYAAMVVGSSLVITLFLGGWSIGFGLDGWLNENVANWV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCCCCHHCCHHHHHH
AVICQLIAYVLKLLFFAFFFVWVRWTLPRFRYDQVMKLGWMVFFELAVINIFLTAAILYF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA