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The map label for this gene is trpF [H]

Identifier: 187736024

GI number: 187736024

Start: 1836657

End: 1837304

Strand: Direct

Name: trpF [H]

Synonym: Amuc_1534

Alternate gene names: 187736024

Gene position: 1836657-1837304 (Clockwise)

Preceding gene: 187736023

Following gene: 187736025

Centisome position: 68.94

GC content: 60.65

Gene sequence:

>648_bases
ATGAAGAAGCATTCATTTGCAATCAAGGTGTGCGGAATTACCCGCCAGAGCGATTTATCAACCGCCATGGGGATGGGGGC
CCATTTCTGCGGCTTCATCTTTCATCCCGGAAGTCCGCGTTATATTGCGCCGTCGCGCGCGGCGGCCCTGGACTCCGCCC
TGATCCGCCGCGTGGGCGTTTTCGTGAACCAGAACGCGGAGGAAATCATGGATATCATGAAAACGGCCCGTCTGGAATTC
GCCCAGCTTCATGGCGCCCATTCTCTGGACTGCGCGCGCCGCATCGGTCCGGAAAAAGTGATCCGCGTATTGTGGCCGGA
CCGGTATGAATCCGTAGATGCCCTGCAAAGGGAAATGGAGCTATGGGCGGACAGCTGCGCCTGGTTTCTGCTGGATGCCG
GCAGCCAGGGCGGCGGCCACGGCGTTTCCCTTGACTGGACCTCCCTGGCGTCTCTGAGTTCCCCCCGGCCCTGGTTCCTG
GCGGGCGGCCTTTCCTCCGCCTCACTGAACAGGGCTCTGGAACAATGCTCTCCGGACGGCATAGACCTGAACTCCGGCGT
GGAAGCCATCCCCGGCCAGAAAAGCCCGCAAAAACTGCTGGCGGCCCTCAAACCACTCACCCCTTACACTCCTTACCACA
TCGCATGA

Upstream 100 bases:

>100_bases
AAGCCGCGGAAGCGGGGTTTCAGGCCGTACTGATGGGAACAGCCCTGATGGACGGAGGAAGGCCGGGTGAAAAACTGGCG
GCAATTTTAGAAGAAACGAT

Downstream 100 bases:

>100_bases
AGAAAGAAGGATATTTCGGCAATTTCGGCGGCCGCTTCGTACCGGAAGCGCTGCGCCCCCCGCTCATGGAGCTGGAGGAA
GCCATGGACTCCATCATGCC

Product: Phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKKHSFAIKVCGITRQSDLSTAMGMGAHFCGFIFHPGSPRYIAPSRAAALDSALIRRVGVFVNQNAEEIMDIMKTARLEF
AQLHGAHSLDCARRIGPEKVIRVLWPDRYESVDALQREMELWADSCAWFLLDAGSQGGGHGVSLDWTSLASLSSPRPWFL
AGGLSSASLNRALEQCSPDGIDLNSGVEAIPGQKSPQKLLAALKPLTPYTPYHIA

Sequences:

>Translated_215_residues
MKKHSFAIKVCGITRQSDLSTAMGMGAHFCGFIFHPGSPRYIAPSRAAALDSALIRRVGVFVNQNAEEIMDIMKTARLEF
AQLHGAHSLDCARRIGPEKVIRVLWPDRYESVDALQREMELWADSCAWFLLDAGSQGGGHGVSLDWTSLASLSSPRPWFL
AGGLSSASLNRALEQCSPDGIDLNSGVEAIPGQKSPQKLLAALKPLTPYTPYHIA
>Mature_215_residues
MKKHSFAIKVCGITRQSDLSTAMGMGAHFCGFIFHPGSPRYIAPSRAAALDSALIRRVGVFVNQNAEEIMDIMKTARLEF
AQLHGAHSLDCARRIGPEKVIRVLWPDRYESVDALQREMELWADSCAWFLLDAGSQGGGHGVSLDWTSLASLSSPRPWFL
AGGLSSASLNRALEQCSPDGIDLNSGVEAIPGQKSPQKLLAALKPLTPYTPYHIA

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=205, Percent_Identity=32.6829268292683, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23362; Mature: 23362

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHSFAIKVCGITRQSDLSTAMGMGAHFCGFIFHPGSPRYIAPSRAAALDSALIRRVGV
CCCCCEEEEEECCCCCHHHHHHHHCCHHHHEEEECCCCCCEECCHHHHHHHHHHHHHHHH
FVNQNAEEIMDIMKTARLEFAQLHGAHSLDCARRIGPEKVIRVLWPDRYESVDALQREME
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHH
LWADSCAWFLLDAGSQGGGHGVSLDWTSLASLSSPRPWFLAGGLSSASLNRALEQCSPDG
HHHHHHHEEEEECCCCCCCCCCEECHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCC
IDLNSGVEAIPGQKSPQKLLAALKPLTPYTPYHIA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKKHSFAIKVCGITRQSDLSTAMGMGAHFCGFIFHPGSPRYIAPSRAAALDSALIRRVGV
CCCCCEEEEEECCCCCHHHHHHHHCCHHHHEEEECCCCCCEECCHHHHHHHHHHHHHHHH
FVNQNAEEIMDIMKTARLEFAQLHGAHSLDCARRIGPEKVIRVLWPDRYESVDALQREME
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHH
LWADSCAWFLLDAGSQGGGHGVSLDWTSLASLSSPRPWFLAGGLSSASLNRALEQCSPDG
HHHHHHHEEEEECCCCCCCCCCEECHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCC
IDLNSGVEAIPGQKSPQKLLAALKPLTPYTPYHIA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA