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The map label for this gene is trpB1 [H]

Identifier: 187736025

GI number: 187736025

Start: 1837301

End: 1838473

Strand: Direct

Name: trpB1 [H]

Synonym: Amuc_1535

Alternate gene names: 187736025

Gene position: 1837301-1838473 (Clockwise)

Preceding gene: 187736024

Following gene: 187736026

Centisome position: 68.97

GC content: 59.68

Gene sequence:

>1173_bases
ATGAAGAAAGAAGGATATTTCGGCAATTTCGGCGGCCGCTTCGTACCGGAAGCGCTGCGCCCCCCGCTCATGGAGCTGGA
GGAAGCCATGGACTCCATCATGCCGTCCAGCGAGTACCGGGATGCGCTTCAGGATCTGCTGGTCAATTACGCGGGCCGTG
AAACTCCCCTCACGTTCTGTCCCCACCTTTCGGAAAAACTGGGCTTCCGCCTGTGGCTGAAACGGGAGGACCTGCTGCAC
ACCGGAGCCCACAAAATCAATAACGCCCTCGGCCAGGCCCTTCTGGCCAAAATGATGGGGAAAACGCATCTTATTGCGGA
AACCGGGGCGGGGCAGCACGGCGTGGCTACGGCTACGGCGGCCGCCCGGCTTAAAATGGACTGCACCATCTTTATGGGCG
CAGAGGATGTAGAACGCCAGTCCATGAACGTTATGCGCATGAAATTGCTGGGAGCGACGGTTTTTCCGATTGAGAGCGGT
TCCCGCACGTTGAAGGATGCCATTAACGAGGCTCTCCGCTACTGGATTTCCCATCAGGCGGATACTCTGTATTGTTTCGG
TACGGCGGCGGGCCCCCATCCGTTCCCCACATTGGTCAGGCAGCTTCAATCCGTCATTGGGCGGGAGGCCCGCGCCCAGA
TGCTGGAGCGTGCAGGCAGGCTGCCGGATGTGGTGGTGGCATGCGTGGGCGGCGGCTCCAATGCCATCGGCATGCTTCAC
CCCTTTGTGGAGGATGAAGGCGTCCGTCTGGTAGGGGTTGAGGCGGGAGGCACCGGTGAGCCCGGCTGTTATAACTCCGC
CCCCATCAATCTGGGCAGCCCCGGCGTGCTGCACGGTCATGTGACCATGCTGTTACAGGATGAGAACGGGCAAATACAGC
CGTCCCATTCCATTTCCGCCGGGCTGGACTATCCCGGGGTAGGCCCGGAACATGCCTATCTGGCGGAAACGGGCCGTGTC
CATTACGGTGTGATTTGCGACGCCTCTGCTTTAAACGCTTTCCGGACGCTCACCAGAGAGGAAGGAATCATTCCTGCGCT
GGAATCCTCCCATGCCGTGGCCTGGGTGCTGGACCATGCGGAGGAACTGCCGCAGGGGGGGGACGTCCTGGTCAATCTCT
CCGGCCGCGGAGACAAGGACCTGGGAATCGTTAAAAAATATTTGAATCTTTAA

Upstream 100 bases:

>100_bases
ACCTGAACTCCGGCGTGGAAGCCATCCCCGGCCAGAAAAGCCCGCAAAAACTGCTGGCGGCCCTCAAACCACTCACCCCT
TACACTCCTTACCACATCGC

Downstream 100 bases:

>100_bases
GCCGCATTCTTCCATGAATAATATGCAGAAATCACCGTTGCAGAAAGCCGTGGAGAGGGCCCATGCCCTCGGCAGGCGTG
CCGTTATCCCTTTCATTACC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKKEGYFGNFGGRFVPEALRPPLMELEEAMDSIMPSSEYRDALQDLLVNYAGRETPLTFCPHLSEKLGFRLWLKREDLLH
TGAHKINNALGQALLAKMMGKTHLIAETGAGQHGVATATAAARLKMDCTIFMGAEDVERQSMNVMRMKLLGATVFPIESG
SRTLKDAINEALRYWISHQADTLYCFGTAAGPHPFPTLVRQLQSVIGREARAQMLERAGRLPDVVVACVGGGSNAIGMLH
PFVEDEGVRLVGVEAGGTGEPGCYNSAPINLGSPGVLHGHVTMLLQDENGQIQPSHSISAGLDYPGVGPEHAYLAETGRV
HYGVICDASALNAFRTLTREEGIIPALESSHAVAWVLDHAEELPQGGDVLVNLSGRGDKDLGIVKKYLNL

Sequences:

>Translated_390_residues
MKKEGYFGNFGGRFVPEALRPPLMELEEAMDSIMPSSEYRDALQDLLVNYAGRETPLTFCPHLSEKLGFRLWLKREDLLH
TGAHKINNALGQALLAKMMGKTHLIAETGAGQHGVATATAAARLKMDCTIFMGAEDVERQSMNVMRMKLLGATVFPIESG
SRTLKDAINEALRYWISHQADTLYCFGTAAGPHPFPTLVRQLQSVIGREARAQMLERAGRLPDVVVACVGGGSNAIGMLH
PFVEDEGVRLVGVEAGGTGEPGCYNSAPINLGSPGVLHGHVTMLLQDENGQIQPSHSISAGLDYPGVGPEHAYLAETGRV
HYGVICDASALNAFRTLTREEGIIPALESSHAVAWVLDHAEELPQGGDVLVNLSGRGDKDLGIVKKYLNL
>Mature_390_residues
MKKEGYFGNFGGRFVPEALRPPLMELEEAMDSIMPSSEYRDALQDLLVNYAGRETPLTFCPHLSEKLGFRLWLKREDLLH
TGAHKINNALGQALLAKMMGKTHLIAETGAGQHGVATATAAARLKMDCTIFMGAEDVERQSMNVMRMKLLGATVFPIESG
SRTLKDAINEALRYWISHQADTLYCFGTAAGPHPFPTLVRQLQSVIGREARAQMLERAGRLPDVVVACVGGGSNAIGMLH
PFVEDEGVRLVGVEAGGTGEPGCYNSAPINLGSPGVLHGHVTMLLQDENGQIQPSHSISAGLDYPGVGPEHAYLAETGRV
HYGVICDASALNAFRTLTREEGIIPALESSHAVAWVLDHAEELPQGGDVLVNLSGRGDKDLGIVKKYLNL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=385, Percent_Identity=57.4025974025974, Blast_Score=425, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=52.8645833333333, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42059; Mature: 42059

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEGYFGNFGGRFVPEALRPPLMELEEAMDSIMPSSEYRDALQDLLVNYAGRETPLTFC
CCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEC
PHLSEKLGFRLWLKREDLLHTGAHKINNALGQALLAKMMGKTHLIAETGAGQHGVATATA
CCHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHH
AARLKMDCTIFMGAEDVERQSMNVMRMKLLGATVFPIESGSRTLKDAINEALRYWISHQA
HHEEEEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
DTLYCFGTAAGPHPFPTLVRQLQSVIGREARAQMLERAGRLPDVVVACVGGGSNAIGMLH
CEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHC
PFVEDEGVRLVGVEAGGTGEPGCYNSAPINLGSPGVLHGHVTMLLQDENGQIQPSHSISA
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCC
GLDYPGVGPEHAYLAETGRVHYGVICDASALNAFRTLTREEGIIPALESSHAVAWVLDHA
CCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHH
EELPQGGDVLVNLSGRGDKDLGIVKKYLNL
HHCCCCCCEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKEGYFGNFGGRFVPEALRPPLMELEEAMDSIMPSSEYRDALQDLLVNYAGRETPLTFC
CCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEC
PHLSEKLGFRLWLKREDLLHTGAHKINNALGQALLAKMMGKTHLIAETGAGQHGVATATA
CCHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHH
AARLKMDCTIFMGAEDVERQSMNVMRMKLLGATVFPIESGSRTLKDAINEALRYWISHQA
HHEEEEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
DTLYCFGTAAGPHPFPTLVRQLQSVIGREARAQMLERAGRLPDVVVACVGGGSNAIGMLH
CEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHC
PFVEDEGVRLVGVEAGGTGEPGCYNSAPINLGSPGVLHGHVTMLLQDENGQIQPSHSISA
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCC
GLDYPGVGPEHAYLAETGRVHYGVICDASALNAFRTLTREEGIIPALESSHAVAWVLDHA
CCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHH
EELPQGGDVLVNLSGRGDKDLGIVKKYLNL
HHCCCCCCEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]