Definition | Akkermansia muciniphila ATCC BAA-835, complete genome. |
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Accession | NC_010655 |
Length | 2,664,102 |
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The map label for this gene is mod [H]
Identifier: 187736011
GI number: 187736011
Start: 1818113
End: 1820011
Strand: Direct
Name: mod [H]
Synonym: Amuc_1521
Alternate gene names: 187736011
Gene position: 1818113-1820011 (Clockwise)
Preceding gene: 187736010
Following gene: 187736012
Centisome position: 68.24
GC content: 43.97
Gene sequence:
>1899_bases ATGGACAAATTGAAAATGCAGAGCCACGATGTGACAAGCTCCAACATAAATAAGATAGCGCGATTGTTCCCGAACTGCGT TACGGAACGGTTAGGTAAGAACGGCAAGCCGGAACTGGCTATCGACTTTGAAAAATTGGAAGCGGAGTTATCCAACGATA TTCTTGCAGAAGGGGAGGAACGCTATCAGTTCACTTGGCCGGACAAGCGGGCGGCAAACCGTTTGGCGAACACTCCCACG ACAATGACGCTCCGCCCGTGTCGGGAGGAATCGGTGGATTTTGACAACACGCAGAATCTTTATATCGAGGGTGACAACCT TGATGTGCTGAAGGTGTTGCGTGAGACATACCTCGGCAAAGTGAAGATGATTTATATTGACCCGCCTTACAACACGGGCA ACGACTTTGTGTACAATGACGAGTTTGCACAAGGCAAGTCGGAGTTTGAGCAAAACAGCGGCTTGTTCGATGAAGAGGGG AATCAGACGATTGACCCGATGTTGCGGAATACGGAAAGCAACGGGCGTTTTCATACGGATTGGCTGAATATGATATATCC GAGGCTGAAGGTGGCCCGCGACTTGCTCTCTGAAGACGGCGTGATTTTCATTTCCATTGATAATAATGAAATCGAAAACC TCCGAAAAATATGCGACGAGATCTTCAGCGAATCTAATTGCATATGTCAATTTGTTTGGAAAAACAAGTATGGAGCAGGA GGGGGCACAAATTCTGTGGCTTATGTTCACGAATATATATTAGCATATTCAAAAACTCCAATAGTGAGTATAAGTTCAGA CTTATCAGAAGACTTAATATCAAGCTATAATAAAACTGATGAAAAGTATAGTACCAGAGGAGGGTACGTTACGCAACCTT TGGCAAGCACAAGTAAGGGTGCAAGAGTAAATTTAATGTACGATATTTTACATGAAGGCAATATAATCAAGCCTCCAAAG GGAGGTAGATGGATTTGGAGTAAAGATAAATTTGACGCTGCTTATGCAAATAATGAAATCGTGATTTCAAAAAATTCAAG TGGATATAGTGTACGTTTCAAACAATATCTTAGAGATAAAAACGGAAAAATGCGTAAAGGTACACCGTTATCTCTAATTG CATCTGTCTTCAATCAAGAGGGTACAAAAGAATTTGCAGAGCTTATGGGGGATAAACGTATCTTTGATTTTCCAAAGCCT TCTGATTTAATAAAATTTTTATTAAGTCTAAATATAAATGGCGGAACTACAGATTTTACTATTATAGACTTCTTTAGCGG TAGTTCATCGACCGCCCATGCTGTGATGAAACTCAATGCCGAGGACGGCGGCAATCGCAAATTCATCATGGTGCAGCTTC CCGAATTGACCGATGAGAAGAGCGAAGCCTATAAAGCCGGATATAAGAATATCTGTGAGATAGGCAAAGAACGCATCCGC CGTGCCGGAAAAAAAATCAAGGAAGAGAATGCCGACAAGGAAGGCATCGATAAGCTCGACACCGGTTTCCGCGTGCTGAA ACTCGACAGCAGCAATATGGAAAATGTCTATTACACTCCGCAAGAGTTTGACGAGCAATCCTTGTTCAATGAGAATGTGA AGCCCGACCGCAGCAGCGAAGATTTGCTGTTCCAAGTGATGCTCGACCTCGGCATTGAACTCTCGGCAAAGATTGAGACG CGGCAAATGGCAGGAAAGAACGTGCATTTTGTGGACGGGAACTATCTGATAGCCTGTTTCGACAAGGACGTGAATGAATC CGCCATTACGGAAATCGCCAGACTGAAGCCGGTATATTTCGTGATGCGCGACGCTTCGGCAGCCAACGACAACGTGATAG ACAATTTCGAGCAGATATTCCGCCACTACTCGCCCGACACGAATTGCAGAATACTGTAG
Upstream 100 bases:
>100_bases TCAGATTGCTGCTTTGGTGCGGAAGATGGCAAGTGAGAAACAGCCTCGGCGCAAACGGGAGTATTTTGAAATAATCAAAA AACTAAAATCAAACCTATAA
Downstream 100 bases:
>100_bases TCATGAAATTCAAGTTTAAGATACAACAATATCAGACGGAGGCGGTGGAGAATACCGTGGCTGTCTTCACGGGGCAGCCC TCGTACGCCATAGAGGGATA
Product: DNA methylase N-4/N-6 domain protein
Products: NA
Alternate protein names: M.StyLTI; StyLTI methyltransferase [H]
Number of amino acids: Translated: 632; Mature: 632
Protein sequence:
>632_residues MDKLKMQSHDVTSSNINKIARLFPNCVTERLGKNGKPELAIDFEKLEAELSNDILAEGEERYQFTWPDKRAANRLANTPT TMTLRPCREESVDFDNTQNLYIEGDNLDVLKVLRETYLGKVKMIYIDPPYNTGNDFVYNDEFAQGKSEFEQNSGLFDEEG NQTIDPMLRNTESNGRFHTDWLNMIYPRLKVARDLLSEDGVIFISIDNNEIENLRKICDEIFSESNCICQFVWKNKYGAG GGTNSVAYVHEYILAYSKTPIVSISSDLSEDLISSYNKTDEKYSTRGGYVTQPLASTSKGARVNLMYDILHEGNIIKPPK GGRWIWSKDKFDAAYANNEIVISKNSSGYSVRFKQYLRDKNGKMRKGTPLSLIASVFNQEGTKEFAELMGDKRIFDFPKP SDLIKFLLSLNINGGTTDFTIIDFFSGSSSTAHAVMKLNAEDGGNRKFIMVQLPELTDEKSEAYKAGYKNICEIGKERIR RAGKKIKEENADKEGIDKLDTGFRVLKLDSSNMENVYYTPQEFDEQSLFNENVKPDRSSEDLLFQVMLDLGIELSAKIET RQMAGKNVHFVDGNYLIACFDKDVNESAITEIARLKPVYFVMRDASAANDNVIDNFEQIFRHYSPDTNCRIL
Sequences:
>Translated_632_residues MDKLKMQSHDVTSSNINKIARLFPNCVTERLGKNGKPELAIDFEKLEAELSNDILAEGEERYQFTWPDKRAANRLANTPT TMTLRPCREESVDFDNTQNLYIEGDNLDVLKVLRETYLGKVKMIYIDPPYNTGNDFVYNDEFAQGKSEFEQNSGLFDEEG NQTIDPMLRNTESNGRFHTDWLNMIYPRLKVARDLLSEDGVIFISIDNNEIENLRKICDEIFSESNCICQFVWKNKYGAG GGTNSVAYVHEYILAYSKTPIVSISSDLSEDLISSYNKTDEKYSTRGGYVTQPLASTSKGARVNLMYDILHEGNIIKPPK GGRWIWSKDKFDAAYANNEIVISKNSSGYSVRFKQYLRDKNGKMRKGTPLSLIASVFNQEGTKEFAELMGDKRIFDFPKP SDLIKFLLSLNINGGTTDFTIIDFFSGSSSTAHAVMKLNAEDGGNRKFIMVQLPELTDEKSEAYKAGYKNICEIGKERIR RAGKKIKEENADKEGIDKLDTGFRVLKLDSSNMENVYYTPQEFDEQSLFNENVKPDRSSEDLLFQVMLDLGIELSAKIET RQMAGKNVHFVDGNYLIACFDKDVNESAITEIARLKPVYFVMRDASAANDNVIDNFEQIFRHYSPDTNCRIL >Mature_632_residues MDKLKMQSHDVTSSNINKIARLFPNCVTERLGKNGKPELAIDFEKLEAELSNDILAEGEERYQFTWPDKRAANRLANTPT TMTLRPCREESVDFDNTQNLYIEGDNLDVLKVLRETYLGKVKMIYIDPPYNTGNDFVYNDEFAQGKSEFEQNSGLFDEEG NQTIDPMLRNTESNGRFHTDWLNMIYPRLKVARDLLSEDGVIFISIDNNEIENLRKICDEIFSESNCICQFVWKNKYGAG GGTNSVAYVHEYILAYSKTPIVSISSDLSEDLISSYNKTDEKYSTRGGYVTQPLASTSKGARVNLMYDILHEGNIIKPPK GGRWIWSKDKFDAAYANNEIVISKNSSGYSVRFKQYLRDKNGKMRKGTPLSLIASVFNQEGTKEFAELMGDKRIFDFPKP SDLIKFLLSLNINGGTTDFTIIDFFSGSSSTAHAVMKLNAEDGGNRKFIMVQLPELTDEKSEAYKAGYKNICEIGKERIR RAGKKIKEENADKEGIDKLDTGFRVLKLDSSNMENVYYTPQEFDEQSLFNENVKPDRSSEDLLFQVMLDLGIELSAKIET RQMAGKNVHFVDGNYLIACFDKDVNESAITEIARLKPVYFVMRDASAANDNVIDNFEQIFRHYSPDTNCRIL
Specific function: Binds the system-specific DNA recognition site 5'-CAGAG- 3'. Necessary for restriction and for methylation of A-4 [H]
COG id: COG2189
COG function: function code L; Adenine specific DNA methylase Mod
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002295 - InterPro: IPR002941 - InterPro: IPR002052 [H]
Pfam domain/function: PF01555 N6_N4_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 71894; Mature: 71894
Theoretical pI: Translated: 4.90; Mature: 4.90
Prosite motif: PS00092 N6_MTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKLKMQSHDVTSSNINKIARLFPNCVTERLGKNGKPELAIDFEKLEAELSNDILAEGEE CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCC RYQFTWPDKRAANRLANTPTTMTLRPCREESVDFDNTQNLYIEGDNLDVLKVLRETYLGK CEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC VKMIYIDPPYNTGNDFVYNDEFAQGKSEFEQNSGLFDEEGNQTIDPMLRNTESNGRFHTD EEEEEECCCCCCCCCCEECCHHHCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCEEHH WLNMIYPRLKVARDLLSEDGVIFISIDNNEIENLRKICDEIFSESNCICQFVWKNKYGAG HHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC GGTNSVAYVHEYILAYSKTPIVSISSDLSEDLISSYNKTDEKYSTRGGYVTQPLASTSKG CCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHCCCCEEECCCCCCCCC ARVNLMYDILHEGNIIKPPKGGRWIWSKDKFDAAYANNEIVISKNSSGYSVRFKQYLRDK CEEEEEEEECCCCCEECCCCCCEEEECCCCCCCEECCCEEEEEECCCCCEEEHHHHHHCC NGKMRKGTPLSLIASVFNQEGTKEFAELMGDKRIFDFPKPSDLIKFLLSLNINGGTTDFT CCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCEEE IIDFFSGSSSTAHAVMKLNAEDGGNRKFIMVQLPELTDEKSEAYKAGYKNICEIGKERIR EEEEECCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH RAGKKIKEENADKEGIDKLDTGFRVLKLDSSNMENVYYTPQEFDEQSLFNENVKPDRSSE HHHHHHHHCCCCHHCHHHHCCCEEEEEECCCCCCCEEECHHHHCHHHHHCCCCCCCCCCH DLLFQVMLDLGIELSAKIETRQMAGKNVHFVDGNYLIACFDKDVNESAITEIARLKPVYF HHHHHHHHHCCCCEEEEEHHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCEEE VMRDASAANDNVIDNFEQIFRHYSPDTNCRIL EEECCCCCCCHHHHHHHHHHHHCCCCCCCEEC >Mature Secondary Structure MDKLKMQSHDVTSSNINKIARLFPNCVTERLGKNGKPELAIDFEKLEAELSNDILAEGEE CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCC RYQFTWPDKRAANRLANTPTTMTLRPCREESVDFDNTQNLYIEGDNLDVLKVLRETYLGK CEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC VKMIYIDPPYNTGNDFVYNDEFAQGKSEFEQNSGLFDEEGNQTIDPMLRNTESNGRFHTD EEEEEECCCCCCCCCCEECCHHHCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCEEHH WLNMIYPRLKVARDLLSEDGVIFISIDNNEIENLRKICDEIFSESNCICQFVWKNKYGAG HHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC GGTNSVAYVHEYILAYSKTPIVSISSDLSEDLISSYNKTDEKYSTRGGYVTQPLASTSKG CCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHCCCCEEECCCCCCCCC ARVNLMYDILHEGNIIKPPKGGRWIWSKDKFDAAYANNEIVISKNSSGYSVRFKQYLRDK CEEEEEEEECCCCCEECCCCCCEEEECCCCCCCEECCCEEEEEECCCCCEEEHHHHHHCC NGKMRKGTPLSLIASVFNQEGTKEFAELMGDKRIFDFPKPSDLIKFLLSLNINGGTTDFT CCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCEEE IIDFFSGSSSTAHAVMKLNAEDGGNRKFIMVQLPELTDEKSEAYKAGYKNICEIGKERIR EEEEECCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH RAGKKIKEENADKEGIDKLDTGFRVLKLDSSNMENVYYTPQEFDEQSLFNENVKPDRSSE HHHHHHHHCCCCHHCHHHHCCCEEEEEECCCCCCCEEECHHHHCHHHHHCCCCCCCCCCH DLLFQVMLDLGIELSAKIETRQMAGKNVHFVDGNYLIACFDKDVNESAITEIARLKPVYF HHHHHHHHHCCCCEEEEEHHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCEEE VMRDASAANDNVIDNFEQIFRHYSPDTNCRIL EEECCCCCCCHHHHHHHHHHHHCCCCCCCEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8387444; 11677609 [H]