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The map label for this gene is fabD [H]

Identifier: 187735997

GI number: 187735997

Start: 1799355

End: 1800281

Strand: Direct

Name: fabD [H]

Synonym: Amuc_1507

Alternate gene names: 187735997

Gene position: 1799355-1800281 (Clockwise)

Preceding gene: 187735996

Following gene: 187736001

Centisome position: 67.54

GC content: 57.28

Gene sequence:

>927_bases
ATGGACGCAGTATTATTGTTTTCCGGACAAGGTGCCCAAAAAGTAGGCATGGGCAAAGATTTGTATGACCAGTATCCCGT
CGCCAAAGCCCTGATTGAACAGGCGGACAAGGCGCTTGGAGAATCCCTTTCTGCCGTCATGTTTGAAGGCCCCGGCGAAG
AACTGACGCGTACCTGCAACTGTCAGCCCGCCCTCTACGTACATGGCCTTGCCTGCCTGGCCGTCTTGAAGGAGCTCGTT
CCCTCCCTGAATCCTGTGGCTGCCGCCGGCCTTTCCCTGGGGGAATTCACGGCTCATGCCGCTGCCGGGACCTATTCTTT
TGAAGAAGGCCTCCGCCTTGTCCAGAAGCGCGGCGCGTTTATGGAGGAAGCATGCAACGCCACGAAAGGCACTATGGCCG
CCATGATCGGCGGCACGGATGAAAACGTCATTAAGCTGGCGCAGGAATGTGACGTGGATGTTGCCAATTTCAATTGCCCC
GGCCAGACAGTCGTTTCCGGTACGGAGGAAGGTGTGGCCAAGGCTGTAGCAGGGGCGAAGGCCGCCGGCTGCAAGATTGC
CAAGAAGCTCAATGTGGCGGGCGCCTACCATTCCCGTCTGATGTACAGCGCTATGGTAAAGCTGGCGGAAGAACTCAAGA
ATATTTCCTTCGGTACGCCGTCCATGCCTGTTTATTGCAATTATGAAGCCCGGGTAGTGGAAGGTCCGGACGACATCCGC
AGCATGCTGGAACACCAGGTATGCGGATCCGTGCGCTGGACGGCTTCCATGCAGAAGCTGGTGGATCAGGGCCACCGCCT
TTTCATTGAACTGGGGCCGGGCAAGACACTGGCCGGCATGATGGCTCGCATCTGCAAGGAAGCTACGGTCATCTCCATTG
AAGACGTGCCCAGCCTGGAAGCCGCCGTTGCGGAGCTGAACAAATAA

Upstream 100 bases:

>100_bases
TGTGAGGCCGGAGCGGATTTTTTATTGGCAATAAGGAAGTTATGGCGATAATATCGCTCTTGCTTCTTTCCTGCCGGAAC
GTTATAATCCAGCTTTAACT

Downstream 100 bases:

>100_bases
TTTCCCTGAATAAAAGGGGGTAAGCCGCCGGCCCGTTGGGGAGCCGGCGGTTTTTTGTTGGCGTGTTCATGGCGGGGTTC
TGTCAAATAGGCAATATCCC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDAVLLFSGQGAQKVGMGKDLYDQYPVAKALIEQADKALGESLSAVMFEGPGEELTRTCNCQPALYVHGLACLAVLKELV
PSLNPVAAAGLSLGEFTAHAAAGTYSFEEGLRLVQKRGAFMEEACNATKGTMAAMIGGTDENVIKLAQECDVDVANFNCP
GQTVVSGTEEGVAKAVAGAKAAGCKIAKKLNVAGAYHSRLMYSAMVKLAEELKNISFGTPSMPVYCNYEARVVEGPDDIR
SMLEHQVCGSVRWTASMQKLVDQGHRLFIELGPGKTLAGMMARICKEATVISIEDVPSLEAAVAELNK

Sequences:

>Translated_308_residues
MDAVLLFSGQGAQKVGMGKDLYDQYPVAKALIEQADKALGESLSAVMFEGPGEELTRTCNCQPALYVHGLACLAVLKELV
PSLNPVAAAGLSLGEFTAHAAAGTYSFEEGLRLVQKRGAFMEEACNATKGTMAAMIGGTDENVIKLAQECDVDVANFNCP
GQTVVSGTEEGVAKAVAGAKAAGCKIAKKLNVAGAYHSRLMYSAMVKLAEELKNISFGTPSMPVYCNYEARVVEGPDDIR
SMLEHQVCGSVRWTASMQKLVDQGHRLFIELGPGKTLAGMMARICKEATVISIEDVPSLEAAVAELNK
>Mature_308_residues
MDAVLLFSGQGAQKVGMGKDLYDQYPVAKALIEQADKALGESLSAVMFEGPGEELTRTCNCQPALYVHGLACLAVLKELV
PSLNPVAAAGLSLGEFTAHAAAGTYSFEEGLRLVQKRGAFMEEACNATKGTMAAMIGGTDENVIKLAQECDVDVANFNCP
GQTVVSGTEEGVAKAVAGAKAAGCKIAKKLNVAGAYHSRLMYSAMVKLAEELKNISFGTPSMPVYCNYEARVVEGPDDIR
SMLEHQVCGSVRWTASMQKLVDQGHRLFIELGPGKTLAGMMARICKEATVISIEDVPSLEAAVAELNK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=297, Percent_Identity=34.6801346801347, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=48.1818181818182, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=39.5424836601307, Blast_Score=180, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71984332, Length=292, Percent_Identity=30.1369863013699, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=327, Percent_Identity=26.9113149847095, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24665753, Length=305, Percent_Identity=34.4262295081967, Blast_Score=154, Evalue=7e-38,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32572; Mature: 32572

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVLLFSGQGAQKVGMGKDLYDQYPVAKALIEQADKALGESLSAVMFEGPGEELTRTCN
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCC
CQPALYVHGLACLAVLKELVPSLNPVAAAGLSLGEFTAHAAAGTYSFEEGLRLVQKRGAF
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCHH
MEEACNATKGTMAAMIGGTDENVIKLAQECDVDVANFNCPGQTVVSGTEEGVAKAVAGAK
HHHHHCCCCCCHHHEECCCCHHHHHHHHHCCCEEECCCCCCCHHHCCCHHHHHHHHHCCH
AAGCKIAKKLNVAGAYHSRLMYSAMVKLAEELKNISFGTPSMPVYCNYEARVVEGPDDIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCHHHHH
SMLEHQVCGSVRWTASMQKLVDQGHRLFIELGPGKTLAGMMARICKEATVISIEDVPSLE
HHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCHHH
AAVAELNK
HHHHHHCC
>Mature Secondary Structure
MDAVLLFSGQGAQKVGMGKDLYDQYPVAKALIEQADKALGESLSAVMFEGPGEELTRTCN
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHCC
CQPALYVHGLACLAVLKELVPSLNPVAAAGLSLGEFTAHAAAGTYSFEEGLRLVQKRGAF
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCHH
MEEACNATKGTMAAMIGGTDENVIKLAQECDVDVANFNCPGQTVVSGTEEGVAKAVAGAK
HHHHHCCCCCCHHHEECCCCHHHHHHHHHCCCEEECCCCCCCHHHCCCHHHHHHHHHCCH
AAGCKIAKKLNVAGAYHSRLMYSAMVKLAEELKNISFGTPSMPVYCNYEARVVEGPDDIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCHHHHH
SMLEHQVCGSVRWTASMQKLVDQGHRLFIELGPGKTLAGMMARICKEATVISIEDVPSLE
HHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCHHH
AAVAELNK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]