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The map label for this gene is avtA [H]

Identifier: 187735978

GI number: 187735978

Start: 1776879

End: 1778153

Strand: Direct

Name: avtA [H]

Synonym: Amuc_1487

Alternate gene names: 187735978

Gene position: 1776879-1778153 (Clockwise)

Preceding gene: 187735972

Following gene: 187735979

Centisome position: 66.7

GC content: 58.82

Gene sequence:

>1275_bases
ATGATGCAATTATCGGAGATCGGAGGCCATCTGACGGCCAGAACGGGTATTGATGATTTGATGGAGGATTTGTTCAAGGC
CCTCCATTCGGGAGACGCCGGCCTGTGCCAGTTGAACGGCGGGAGCCCCGCCGTTATTCCTGAGGTGACGGAACTTTGGC
GGCGCAGCATGGGGGAACTGGTGCGAAATGGCAAATTTGACGTGCTGGTGGGCCATTATGCCCATCCGGGCGGGGATCCT
GCCTTTATCCGTGCCCTGGTGTGTTTTCTCAATGAACGTTGCGGATGGAACCTGACGCCGGAAAATGTGGCGATTACCCA
GGGTGGCCAGATGGCCTGCTTTACACTGTTCAACATGCTGGCGGGCCCGTGCCCGGACGGTGCTGTGCGTGAAATCCTTT
TTCCCCTGTGCCCGGATTATGTGGGATACCAGTCCCAATCCCTGTGCGGCGGCGTCATGTTCCGGGGCATCCGGCCCGGC
ATCCGCATGCTGGACGGGCACACGTTCAAGTACGTGATTGATTTTGACCGTCTGGACATACGTCCGGAAACGGCCGCCGT
CTGCATGTCCCGGCCTACGAATCCCACCGGGAACGTGGTGACGGATGAGGAATTGGGGCTTCTGCGGGAAATGACTTCCC
GCGCCGGGGTTCCCCTGATGATTGACAATGCTTACGGGCCTCCGTTGCCCAATATTTGTTTTGTGCCCGTAACCCCGGCC
TGGGATGAGAACATGATCCTGACCATGAGCCTGTCCAAGATCGGGTTGCCCGGAACGCGCACCGGCATTGTCATTGCGCG
CCCGGAGATCATTCGTGCCGTCGTGAGCATGGTGACTACGTCATCCCTGTGCCCGAACAATCTGGGCCAGGCTCTGGTGA
CGCCTTATCTGGAAGACGGCACTCTGGAGAGAGTCTGCCGTGAAACCCTCACGCCGTTTTACCGCGGCCGGGCGGAATTC
GCCCTGTCCCTGCTGCCGAAACTTTTCGGAGAATCCATCCCCTGGCGCGTTCATAAGAGTGAGGGCGCCATGTTCCTGTG
GCTGTGGTTTGAGGGATTGCCCATCACGTGCCAGGAGCTTTACGAACGGTGCAAGTCACGGGGCTGTTTTGTAAATCCCG
GCCATCACTTTTTCTTCGCCCTTCCGGAGGAGGGGGAACCCTGGCCGCACCGTCATGAATGCATCCGCATCAGCTTCACC
CAGACGGAGGAACTCCTGCGCAAGGGGCTTTCCATCGTGGCGGATGAAGTGCGCAAGGCCTACTCCCGTTCTTAA

Upstream 100 bases:

>100_bases
TTATGAACCTTAACGGAGGGGAAAGTCAAACTGTTCATGCGCCCTCCGGAACAATGATTTTTCTCGCATAAAACGCGTAT
GCGGCTACAATGCCCGCGGC

Downstream 100 bases:

>100_bases
TCCAAACCTGACCCGTATCCATGAACAGCATGACCGGTTTCGGCAGAGCCGCCGCCCAGACAGACCGTTATAATATCCTT
GTTGAAATATCAGGCGTAAA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MMQLSEIGGHLTARTGIDDLMEDLFKALHSGDAGLCQLNGGSPAVIPEVTELWRRSMGELVRNGKFDVLVGHYAHPGGDP
AFIRALVCFLNERCGWNLTPENVAITQGGQMACFTLFNMLAGPCPDGAVREILFPLCPDYVGYQSQSLCGGVMFRGIRPG
IRMLDGHTFKYVIDFDRLDIRPETAAVCMSRPTNPTGNVVTDEELGLLREMTSRAGVPLMIDNAYGPPLPNICFVPVTPA
WDENMILTMSLSKIGLPGTRTGIVIARPEIIRAVVSMVTTSSLCPNNLGQALVTPYLEDGTLERVCRETLTPFYRGRAEF
ALSLLPKLFGESIPWRVHKSEGAMFLWLWFEGLPITCQELYERCKSRGCFVNPGHHFFFALPEEGEPWPHRHECIRISFT
QTEELLRKGLSIVADEVRKAYSRS

Sequences:

>Translated_424_residues
MMQLSEIGGHLTARTGIDDLMEDLFKALHSGDAGLCQLNGGSPAVIPEVTELWRRSMGELVRNGKFDVLVGHYAHPGGDP
AFIRALVCFLNERCGWNLTPENVAITQGGQMACFTLFNMLAGPCPDGAVREILFPLCPDYVGYQSQSLCGGVMFRGIRPG
IRMLDGHTFKYVIDFDRLDIRPETAAVCMSRPTNPTGNVVTDEELGLLREMTSRAGVPLMIDNAYGPPLPNICFVPVTPA
WDENMILTMSLSKIGLPGTRTGIVIARPEIIRAVVSMVTTSSLCPNNLGQALVTPYLEDGTLERVCRETLTPFYRGRAEF
ALSLLPKLFGESIPWRVHKSEGAMFLWLWFEGLPITCQELYERCKSRGCFVNPGHHFFFALPEEGEPWPHRHECIRISFT
QTEELLRKGLSIVADEVRKAYSRS
>Mature_424_residues
MMQLSEIGGHLTARTGIDDLMEDLFKALHSGDAGLCQLNGGSPAVIPEVTELWRRSMGELVRNGKFDVLVGHYAHPGGDP
AFIRALVCFLNERCGWNLTPENVAITQGGQMACFTLFNMLAGPCPDGAVREILFPLCPDYVGYQSQSLCGGVMFRGIRPG
IRMLDGHTFKYVIDFDRLDIRPETAAVCMSRPTNPTGNVVTDEELGLLREMTSRAGVPLMIDNAYGPPLPNICFVPVTPA
WDENMILTMSLSKIGLPGTRTGIVIARPEIIRAVVSMVTTSSLCPNNLGQALVTPYLEDGTLERVCRETLTPFYRGRAEF
ALSLLPKLFGESIPWRVHKSEGAMFLWLWFEGLPITCQELYERCKSRGCFVNPGHHFFFALPEEGEPWPHRHECIRISFT
QTEELLRKGLSIVADEVRKAYSRS

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=423, Percent_Identity=41.371158392435, Blast_Score=347, Evalue=9e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 47098; Mature: 47098

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQLSEIGGHLTARTGIDDLMEDLFKALHSGDAGLCQLNGGSPAVIPEVTELWRRSMGEL
CCCHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
VRNGKFDVLVGHYAHPGGDPAFIRALVCFLNERCGWNLTPENVAITQGGQMACFTLFNML
HHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHH
AGPCPDGAVREILFPLCPDYVGYQSQSLCGGVMFRGIRPGIRMLDGHTFKYVIDFDRLDI
CCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCC
RPETAAVCMSRPTNPTGNVVTDEELGLLREMTSRAGVPLMIDNAYGPPLPNICFVPVTPA
CCHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCCC
WDENMILTMSLSKIGLPGTRTGIVIARPEIIRAVVSMVTTSSLCPNNLGQALVTPYLEDG
CCCCEEEEEEHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
TLERVCRETLTPFYRGRAEFALSLLPKLFGESIPWRVHKSEGAMFLWLWFEGLPITCQEL
HHHHHHHHHHCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCHHHH
YERCKSRGCFVNPGHHFFFALPEEGEPWPHRHECIRISFTQTEELLRKGLSIVADEVRKA
HHHHHHCCCEECCCCEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
YSRS
HCCC
>Mature Secondary Structure
MMQLSEIGGHLTARTGIDDLMEDLFKALHSGDAGLCQLNGGSPAVIPEVTELWRRSMGEL
CCCHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
VRNGKFDVLVGHYAHPGGDPAFIRALVCFLNERCGWNLTPENVAITQGGQMACFTLFNML
HHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHH
AGPCPDGAVREILFPLCPDYVGYQSQSLCGGVMFRGIRPGIRMLDGHTFKYVIDFDRLDI
CCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCC
RPETAAVCMSRPTNPTGNVVTDEELGLLREMTSRAGVPLMIDNAYGPPLPNICFVPVTPA
CCHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCCC
WDENMILTMSLSKIGLPGTRTGIVIARPEIIRAVVSMVTTSSLCPNNLGQALVTPYLEDG
CCCCEEEEEEHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCC
TLERVCRETLTPFYRGRAEFALSLLPKLFGESIPWRVHKSEGAMFLWLWFEGLPITCQEL
HHHHHHHHHHCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCHHHH
YERCKSRGCFVNPGHHFFFALPEEGEPWPHRHECIRISFTQTEELLRKGLSIVADEVRKA
HHHHHHCCCEECCCCEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
YSRS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]