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The map label for this gene is gph [C]

Identifier: 187735953

GI number: 187735953

Start: 1752726

End: 1753718

Strand: Direct

Name: gph [C]

Synonym: Amuc_1462

Alternate gene names: 187735953

Gene position: 1752726-1753718 (Clockwise)

Preceding gene: 187735952

Following gene: 187735959

Centisome position: 65.79

GC content: 56.39

Gene sequence:

>993_bases
ATGTTTAAAAATATCATTTTCGACTGGTCCGGCACCCTGGTGGACGACCTGGCCCTGACGCTGGACGCCTCCAACTACGT
TTTTTCCCAATACGGGAAACCCTGCATGAACAGGGATGAATTTCGCGCGGAATTCCAGCTTCCCTATCCGGACTATTATG
CCCGGGTGCTGCCCCACGCGGATCTGGATGAACTGGAAGACCATTTCCGGTACGCCTTCCGCGTTTCCAATGCTCCGGTG
GAAGTGCTGCCGAATGCCCGGGAATTCCTGGAGTTCTGCCGCGCGCGTGGCGTGCGCTGCTTTATTCTTACCAGCGTGGA
CGCCAAGGAGTTTGATACCCAATGCAGGGAGCTGGGCATGATGGAATATTTTGAAGCCATTCATGCGGGCATCCGCCATA
AGGATGCCCACATTCATACCCTGCTGGCCCAGCACGGGCTGCATGCCCATGAAACCGCGTTTATCGGGGACATGCAGCAT
GATGTGGAAACGGCTCACCACGCGGGCATCACATCCATTGCCGTTTTGACCGGCTACAATGACGCAGCGCAGCTTTCCAA
GGCTAGGCCGGACATGATCGTCCCGGACCTGCTTGTTCTGCGCACGCTGATGCGCCGTTACGCGCTCCCTTCCGATACGC
AGGATTCCATCAATATCAATGGTCTTGAACTGGATACCTTCATTGGCGTTCCGGACGAGGAGCGCTCTTCCATGCAGACC
CTGAAAGCGGACATCTCTTTTTATCCGGAGGAGGCTTTGTCCGGCCTGAACGATGATTTTTCCAGAACCGTCTGTTATGA
TTCCATTGCCCGTGCGCTCCGGGCAGAGGCCATGGCGCGTCCACGCAAGCTGGTGGAAACGCTGGCAGAGGATATGGGAA
AGGTTTGCCTGAAGGAATTCGGCGCGCGGCACGTGGTTGTTACCCTGCGCAAGTTTATTCTGCCGCGGACGGACAGCGTT
TCCGTAACGGTGCATGTTTCCCGGCACCGGTAA

Upstream 100 bases:

>100_bases
CACGCTTGGCCCTATCGTTCTCCGGGTGGAGACGGCCGCCTTTTTCGGCCTGGCCGCCATGCGGTACGCCCTGGACTGAG
TTTTTTTCATACGCATTCCC

Downstream 100 bases:

>100_bases
GAAAGAGGTTTTCTACCGGATATCCACCGCCTTTTCCTCAGGGATTTTCTTCCCGTCTTTGGTGAAAGTGTTTTTCTCCG
CCTTGACGTCACCGGTATGG

Product: Haloacid dehalogenase domain protein hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MFKNIIFDWSGTLVDDLALTLDASNYVFSQYGKPCMNRDEFRAEFQLPYPDYYARVLPHADLDELEDHFRYAFRVSNAPV
EVLPNAREFLEFCRARGVRCFILTSVDAKEFDTQCRELGMMEYFEAIHAGIRHKDAHIHTLLAQHGLHAHETAFIGDMQH
DVETAHHAGITSIAVLTGYNDAAQLSKARPDMIVPDLLVLRTLMRRYALPSDTQDSININGLELDTFIGVPDEERSSMQT
LKADISFYPEEALSGLNDDFSRTVCYDSIARALRAEAMARPRKLVETLAEDMGKVCLKEFGARHVVVTLRKFILPRTDSV
SVTVHVSRHR

Sequences:

>Translated_330_residues
MFKNIIFDWSGTLVDDLALTLDASNYVFSQYGKPCMNRDEFRAEFQLPYPDYYARVLPHADLDELEDHFRYAFRVSNAPV
EVLPNAREFLEFCRARGVRCFILTSVDAKEFDTQCRELGMMEYFEAIHAGIRHKDAHIHTLLAQHGLHAHETAFIGDMQH
DVETAHHAGITSIAVLTGYNDAAQLSKARPDMIVPDLLVLRTLMRRYALPSDTQDSININGLELDTFIGVPDEERSSMQT
LKADISFYPEEALSGLNDDFSRTVCYDSIARALRAEAMARPRKLVETLAEDMGKVCLKEFGARHVVVTLRKFILPRTDSV
SVTVHVSRHR
>Mature_330_residues
MFKNIIFDWSGTLVDDLALTLDASNYVFSQYGKPCMNRDEFRAEFQLPYPDYYARVLPHADLDELEDHFRYAFRVSNAPV
EVLPNAREFLEFCRARGVRCFILTSVDAKEFDTQCRELGMMEYFEAIHAGIRHKDAHIHTLLAQHGLHAHETAFIGDMQH
DVETAHHAGITSIAVLTGYNDAAQLSKARPDMIVPDLLVLRTLMRRYALPSDTQDSININGLELDTFIGVPDEERSSMQT
LKADISFYPEEALSGLNDDFSRTVCYDSIARALRAEAMARPRKLVETLAEDMGKVCLKEFGARHVVVTLRKFILPRTDSV
SVTVHVSRHR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 37527; Mature: 37527

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNIIFDWSGTLVDDLALTLDASNYVFSQYGKPCMNRDEFRAEFQLPYPDYYARVLPHA
CCCCEEECCCCCHHHHHHHEECCCHHHHHHCCCCCCCCHHCCEEEECCCCHHHHHHCCCC
DLDELEDHFRYAFRVSNAPVEVLPNAREFLEFCRARGVRCFILTSVDAKEFDTQCRELGM
CHHHHHHHHHHHHEECCCCCEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCH
MEYFEAIHAGIRHKDAHIHTLLAQHGLHAHETAFIGDMQHDVETAHHAGITSIAVLTGYN
HHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCHHEEEEEECCC
DAAQLSKARPDMIVPDLLVLRTLMRRYALPSDTQDSININGLELDTFIGVPDEERSSMQT
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEEECCCCHHHHHHHH
LKADISFYPEEALSGLNDDFSRTVCYDSIARALRAEAMARPRKLVETLAEDMGKVCLKEF
HHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GARHVVVTLRKFILPRTDSVSVTVHVSRHR
CCCHHHHHHHHHHCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MFKNIIFDWSGTLVDDLALTLDASNYVFSQYGKPCMNRDEFRAEFQLPYPDYYARVLPHA
CCCCEEECCCCCHHHHHHHEECCCHHHHHHCCCCCCCCHHCCEEEECCCCHHHHHHCCCC
DLDELEDHFRYAFRVSNAPVEVLPNAREFLEFCRARGVRCFILTSVDAKEFDTQCRELGM
CHHHHHHHHHHHHEECCCCCEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCH
MEYFEAIHAGIRHKDAHIHTLLAQHGLHAHETAFIGDMQHDVETAHHAGITSIAVLTGYN
HHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCHHEEEEEECCC
DAAQLSKARPDMIVPDLLVLRTLMRRYALPSDTQDSININGLELDTFIGVPDEERSSMQT
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCEEEEEEECCCCHHHHHHHH
LKADISFYPEEALSGLNDDFSRTVCYDSIARALRAEAMARPRKLVETLAEDMGKVCLKEF
HHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GARHVVVTLRKFILPRTDSVSVTVHVSRHR
CCCHHHHHHHHHHCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA