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The map label for this gene is argJ [H]

Identifier: 187735939

GI number: 187735939

Start: 1738968

End: 1740221

Strand: Direct

Name: argJ [H]

Synonym: Amuc_1448

Alternate gene names: 187735939

Gene position: 1738968-1740221 (Clockwise)

Preceding gene: 187735938

Following gene: 187735940

Centisome position: 65.27

GC content: 58.29

Gene sequence:

>1254_bases
ATGAATGATTCATCCTATATTCCGGTTGACGGGGGCGTTTGCGCGCCCCAGGGCTTTTTGGGGAGCGCCGTAAGCTGCGG
CATCAAGAAGCCTACGGCCACGCGTCTGGACCTGGCCCTGATTTATTCCACGGAACCCTGCGTTTCCGCAGGAACGTTTA
CGACCAACCGCGTGCAGGCCGCCTGCGTGAAGGTGAGCCGGGAGCATCTCCGGAAAGGAAATATCCGCGCCATCGTGGCG
AACAGCGGGAACGCGAACGCCTGCACCGGAACCCGGGGGGTGGAGGACGCCAGGGGTGAATGCCGCAGCGTTGCTGAGCT
TCTGGGGCTGGAGCCTGCAGAAGTGGCCGTATGTTCCACCGGCGTGATTGGCCTGCCAATGCCTATGATGCGCATTTACC
CGAAGTTTCCGGAATTGGCGGAGGGGCTTTCCCGCGACAAGGGGCATGAGGTGGCTCAGGCCGTGATGACCAGTGATACG
AAGGAGAAAATTATTGCCATTGAGTTTGTAGTGCAGGGCAAACCCGTGCGCATCGGCGCCTGCTGCAAGGGGGCGGGCAT
GATCAATCCCTGCATGGCGACCATGCTGTGCTTTATCACGACGGATGCGGGCGTTTCCCGCGATGTGCTGGAGCTGTGCG
TGCAGTCCGGAGTGAAGAGTTCTTTTAACTGCATCACCATTGACGGAGACATGAGCACGAATGACACGGTTCTGGTGATG
GCGAATGGGGCATCCGGCGTGAAGCTGGAAACTCCGGAAGATATTTACGCATTCCAGCAGGCTTTGGCCCATGTGATGCT
GGAACTGGCCAAGCACATCGTGCAGGACGGAGAGCGGGTGACCAAGTTCGTCACCGTGCATGTGACGGGAGGCCGCACGG
AGGATGAAGCGAAAAAAGCGGCGGAAGCCGTAGCCAAGTCTTCCCTGGTAAAGAGTTCCTGGAACGGGAATGATCCCAAC
TGGGGGCGCATTATTCATGCCGTGGGCTACTGCGGAGCAAAAGTGGACGAAGAGAAGATAGACATTGACATCGCTGGTCT
GGCCGCCTGCCGCGGCGGCGTGCAGGCGGATACTCCGTCCGACGATTTGCGGCAAGCCGTGCAGGTTCCCGCGTTCCAGG
TGGATATCAATTTGAATCGGGGCGAGTTTTCCCATACGGTGTATACCACGGATTTGTCTCCGGAATATGTGGATTTCAAC
CGTTCCGAGTATGCATACTGGAACCAGGCGAAAGCGGACGGCCTGACCTGTTAA

Upstream 100 bases:

>100_bases
GCAGGCCGTTCAGTCCTTCAATATCATGTGCGGATTTGATGAAACGGAAGGCTTGTGGGTTCTGTAGCTTTTTGATACGC
TGAAAGGCACTTTCAAGACG

Downstream 100 bases:

>100_bases
CCGTTTCTGTCATGGCGCGTGGCAAATGCCGCCAGGGAAAGGCGGGGGGAATGGCCCCCGCCGCCGGGATGCTGATGGAG
GTGCGGCGCCTTCTGGATGA

Product: arginine biosynthesis bifunctional protein ArgJ

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNDSSYIPVDGGVCAPQGFLGSAVSCGIKKPTATRLDLALIYSTEPCVSAGTFTTNRVQAACVKVSREHLRKGNIRAIVA
NSGNANACTGTRGVEDARGECRSVAELLGLEPAEVAVCSTGVIGLPMPMMRIYPKFPELAEGLSRDKGHEVAQAVMTSDT
KEKIIAIEFVVQGKPVRIGACCKGAGMINPCMATMLCFITTDAGVSRDVLELCVQSGVKSSFNCITIDGDMSTNDTVLVM
ANGASGVKLETPEDIYAFQQALAHVMLELAKHIVQDGERVTKFVTVHVTGGRTEDEAKKAAEAVAKSSLVKSSWNGNDPN
WGRIIHAVGYCGAKVDEEKIDIDIAGLAACRGGVQADTPSDDLRQAVQVPAFQVDINLNRGEFSHTVYTTDLSPEYVDFN
RSEYAYWNQAKADGLTC

Sequences:

>Translated_417_residues
MNDSSYIPVDGGVCAPQGFLGSAVSCGIKKPTATRLDLALIYSTEPCVSAGTFTTNRVQAACVKVSREHLRKGNIRAIVA
NSGNANACTGTRGVEDARGECRSVAELLGLEPAEVAVCSTGVIGLPMPMMRIYPKFPELAEGLSRDKGHEVAQAVMTSDT
KEKIIAIEFVVQGKPVRIGACCKGAGMINPCMATMLCFITTDAGVSRDVLELCVQSGVKSSFNCITIDGDMSTNDTVLVM
ANGASGVKLETPEDIYAFQQALAHVMLELAKHIVQDGERVTKFVTVHVTGGRTEDEAKKAAEAVAKSSLVKSSWNGNDPN
WGRIIHAVGYCGAKVDEEKIDIDIAGLAACRGGVQADTPSDDLRQAVQVPAFQVDINLNRGEFSHTVYTTDLSPEYVDFN
RSEYAYWNQAKADGLTC
>Mature_417_residues
MNDSSYIPVDGGVCAPQGFLGSAVSCGIKKPTATRLDLALIYSTEPCVSAGTFTTNRVQAACVKVSREHLRKGNIRAIVA
NSGNANACTGTRGVEDARGECRSVAELLGLEPAEVAVCSTGVIGLPMPMMRIYPKFPELAEGLSRDKGHEVAQAVMTSDT
KEKIIAIEFVVQGKPVRIGACCKGAGMINPCMATMLCFITTDAGVSRDVLELCVQSGVKSSFNCITIDGDMSTNDTVLVM
ANGASGVKLETPEDIYAFQQALAHVMLELAKHIVQDGERVTKFVTVHVTGGRTEDEAKKAAEAVAKSSLVKSSWNGNDPN
WGRIIHAVGYCGAKVDEEKIDIDIAGLAACRGGVQADTPSDDLRQAVQVPAFQVDINLNRGEFSHTVYTTDLSPEYVDFN
RSEYAYWNQAKADGLTC

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=422, Percent_Identity=36.2559241706161, Blast_Score=207, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 44441; Mature: 44441

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSSYIPVDGGVCAPQGFLGSAVSCGIKKPTATRLDLALIYSTEPCVSAGTFTTNRVQA
CCCCCEEECCCCCCCCCCHHCHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHH
ACVKVSREHLRKGNIRAIVANSGNANACTGTRGVEDARGECRSVAELLGLEPAEVAVCST
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEECC
GVIGLPMPMMRIYPKFPELAEGLSRDKGHEVAQAVMTSDTKEKIIAIEFVVQGKPVRIGA
CCCCCCCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEE
CCKGAGMINPCMATMLCFITTDAGVSRDVLELCVQSGVKSSFNCITIDGDMSTNDTVLVM
ECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEE
ANGASGVKLETPEDIYAFQQALAHVMLELAKHIVQDGERVTKFVTVHVTGGRTEDEAKKA
ECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHH
AEAVAKSSLVKSSWNGNDPNWGRIIHAVGYCGAKVDEEKIDIDIAGLAACRGGVQADTPS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCCCCCH
DDLRQAVQVPAFQVDINLNRGEFSHTVYTTDLSPEYVDFNRSEYAYWNQAKADGLTC
HHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDSSYIPVDGGVCAPQGFLGSAVSCGIKKPTATRLDLALIYSTEPCVSAGTFTTNRVQA
CCCCCEEECCCCCCCCCCHHCHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHH
ACVKVSREHLRKGNIRAIVANSGNANACTGTRGVEDARGECRSVAELLGLEPAEVAVCST
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEECC
GVIGLPMPMMRIYPKFPELAEGLSRDKGHEVAQAVMTSDTKEKIIAIEFVVQGKPVRIGA
CCCCCCCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEE
CCKGAGMINPCMATMLCFITTDAGVSRDVLELCVQSGVKSSFNCITIDGDMSTNDTVLVM
ECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEE
ANGASGVKLETPEDIYAFQQALAHVMLELAKHIVQDGERVTKFVTVHVTGGRTEDEAKKA
ECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHH
AEAVAKSSLVKSSWNGNDPNWGRIIHAVGYCGAKVDEEKIDIDIAGLAACRGGVQADTPS
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCCCCCH
DDLRQAVQVPAFQVDINLNRGEFSHTVYTTDLSPEYVDFNRSEYAYWNQAKADGLTC
HHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]