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The map label for this gene is argC

Identifier: 187735938

GI number: 187735938

Start: 1737891

End: 1738934

Strand: Direct

Name: argC

Synonym: Amuc_1447

Alternate gene names: 187735938

Gene position: 1737891-1738934 (Clockwise)

Preceding gene: 187735935

Following gene: 187735939

Centisome position: 65.23

GC content: 60.06

Gene sequence:

>1044_bases
ATGAAGCAAGTTCAAGTTGCAGTCGTCGGGGCCAGTGGCTACACCGGGCAGGAATTGTTGCGCATCCTGCTGAACCATCG
CGGGGTGAAGCTGGTGTGCGCTACTTCCCGCCAGTATGCCGGGCAGCCGTTGTGGGAGGTTTTTCCCCGTTTTCGTCAGG
TTCCGGGTTCCGGCCTGAAGTTTACGGATTCCGATGTGGAGGCGATTGCCGCCACTGGGGCGGAGGTCGCTTTTCTGGCC
CTGCCTCATGGCGTGGCTGCTTCCTATGCCCGCGGCCTGGTGGACAGGGGCGTGCGCGTGATTGACCTGAGCGCGGATTT
TCGCCTGGACAGCCCGGATGTGTACGAAGAGTATTACGGGAACCCCCACCCGGATACGGCCCTGATGCAGGAAGCCGTGT
ACGGTTTGCCGGAGTGGCGCCGGGAGGAGATTGCCCGGGCGCGCATTGTGGCTTCCCCCGGCTGCTATCCCACCAGCATT
CTTCTGCCTCTCATTCCCTTGTTCAGGGCGGGCATGCTGGAGCCGGAGGACGTGGTGGCCTGTTCCGGCAGCGGCGTGAG
CGGAGCAGGGCGCAAGGCATCCATTCCGCTGCTGTTCTGCGAGTGCAATGAGAGTTTTCATGCTTACGGAGTACCGAAAC
ACCGCCATTTGAGCGAAATTGAGCAGGAGCTTTCCCATGCCGCCGGGGAAACGGTGGTGATGTCCTTCACCCCCCATTTG
ATTCCCGTTAATACGGGTATTTGCTCCACGATTACGGCCAAAGTGAAAAAAGGGGCGGACCCCGAGTCCGTCGGCCGCCT
GCTGGAAGAAGCCTATGCTGCGGCCCCGTTCGTCCGCCTTCTGGGGCGTAACCAGCCTGCGGATACCAAGAATGTAACAC
GGACGAACTGCGTGGATATTGGCTGGGCTTATGATCCCCGCACGAACCGCGTGATTCTGATGAGCGCAGAGGATAATGTG
GTGAAGGGCGCGGGTGGGCAGGCCGTTCAGTCCTTCAATATCATGTGCGGATTTGATGAAACGGAAGGCTTGTGGGTTCT
GTAG

Upstream 100 bases:

>100_bases
GAACTCGGACCGACCGGGGTCGTGTCTTGTGACGGCGAGGTGTATATAGGAAAACTTTAGTGTTGGCAAGAGTCTTTTTT
CATAGCATACCTTTTTTGTC

Downstream 100 bases:

>100_bases
CTTTTTGATACGCTGAAAGGCACTTTCAAGACGATGAATGATTCATCCTATATTCCGGTTGACGGGGGCGTTTGCGCGCC
CCAGGGCTTTTTGGGGAGCG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKQVQVAVVGASGYTGQELLRILLNHRGVKLVCATSRQYAGQPLWEVFPRFRQVPGSGLKFTDSDVEAIAATGAEVAFLA
LPHGVAASYARGLVDRGVRVIDLSADFRLDSPDVYEEYYGNPHPDTALMQEAVYGLPEWRREEIARARIVASPGCYPTSI
LLPLIPLFRAGMLEPEDVVACSGSGVSGAGRKASIPLLFCECNESFHAYGVPKHRHLSEIEQELSHAAGETVVMSFTPHL
IPVNTGICSTITAKVKKGADPESVGRLLEEAYAAAPFVRLLGRNQPADTKNVTRTNCVDIGWAYDPRTNRVILMSAEDNV
VKGAGGQAVQSFNIMCGFDETEGLWVL

Sequences:

>Translated_347_residues
MKQVQVAVVGASGYTGQELLRILLNHRGVKLVCATSRQYAGQPLWEVFPRFRQVPGSGLKFTDSDVEAIAATGAEVAFLA
LPHGVAASYARGLVDRGVRVIDLSADFRLDSPDVYEEYYGNPHPDTALMQEAVYGLPEWRREEIARARIVASPGCYPTSI
LLPLIPLFRAGMLEPEDVVACSGSGVSGAGRKASIPLLFCECNESFHAYGVPKHRHLSEIEQELSHAAGETVVMSFTPHL
IPVNTGICSTITAKVKKGADPESVGRLLEEAYAAAPFVRLLGRNQPADTKNVTRTNCVDIGWAYDPRTNRVILMSAEDNV
VKGAGGQAVQSFNIMCGFDETEGLWVL
>Mature_347_residues
MKQVQVAVVGASGYTGQELLRILLNHRGVKLVCATSRQYAGQPLWEVFPRFRQVPGSGLKFTDSDVEAIAATGAEVAFLA
LPHGVAASYARGLVDRGVRVIDLSADFRLDSPDVYEEYYGNPHPDTALMQEAVYGLPEWRREEIARARIVASPGCYPTSI
LLPLIPLFRAGMLEPEDVVACSGSGVSGAGRKASIPLLFCECNESFHAYGVPKHRHLSEIEQELSHAAGETVVMSFTPHL
IPVNTGICSTITAKVKKGADPESVGRLLEEAYAAAPFVRLLGRNQPADTKNVTRTNCVDIGWAYDPRTNRVILMSAEDNV
VKGAGGQAVQSFNIMCGFDETEGLWVL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=341, Percent_Identity=39.0029325513196, Blast_Score=191, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6320913, Length=346, Percent_Identity=27.4566473988439, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_AKKM8 (B2UKZ6)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001878050.1
- ProteinModelPortal:   B2UKZ6
- SMR:   B2UKZ6
- GeneID:   6275797
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1447
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   CLSK2335560
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37587; Mature: 37587

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVQVAVVGASGYTGQELLRILLNHRGVKLVCATSRQYAGQPLWEVFPRFRQVPGSGLK
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHCCCCCCE
FTDSDVEAIAATGAEVAFLALPHGVAASYARGLVDRGVRVIDLSADFRLDSPDVYEEYYG
ECCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHCC
NPHPDTALMQEAVYGLPEWRREEIARARIVASPGCYPTSILLPLIPLFRAGMLEPEDVVA
CCCCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCHHEEE
CSGSGVSGAGRKASIPLLFCECNESFHAYGVPKHRHLSEIEQELSHAAGETVVMSFTPHL
ECCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCE
IPVNTGICSTITAKVKKGADPESVGRLLEEAYAAAPFVRLLGRNQPADTKNVTRTNCVDI
EEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
GWAYDPRTNRVILMSAEDNVVKGAGGQAVQSFNIMCGFDETEGLWVL
CCCCCCCCCEEEEEECCCCEEECCCCCCEEEEEEEECCCCCCCEEEC
>Mature Secondary Structure
MKQVQVAVVGASGYTGQELLRILLNHRGVKLVCATSRQYAGQPLWEVFPRFRQVPGSGLK
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHHCCCCCCE
FTDSDVEAIAATGAEVAFLALPHGVAASYARGLVDRGVRVIDLSADFRLDSPDVYEEYYG
ECCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHCC
NPHPDTALMQEAVYGLPEWRREEIARARIVASPGCYPTSILLPLIPLFRAGMLEPEDVVA
CCCCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCHHEEE
CSGSGVSGAGRKASIPLLFCECNESFHAYGVPKHRHLSEIEQELSHAAGETVVMSFTPHL
ECCCCCCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCE
IPVNTGICSTITAKVKKGADPESVGRLLEEAYAAAPFVRLLGRNQPADTKNVTRTNCVDI
EEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
GWAYDPRTNRVILMSAEDNVVKGAGGQAVQSFNIMCGFDETEGLWVL
CCCCCCCCCEEEEEECCCCEEECCCCCCEEEEEEEECCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA