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The map label for this gene is hypD [H]

Identifier: 187735894

GI number: 187735894

Start: 1674401

End: 1675468

Strand: Direct

Name: hypD [H]

Synonym: Amuc_1401

Alternate gene names: 187735894

Gene position: 1674401-1675468 (Clockwise)

Preceding gene: 187735893

Following gene: 187735895

Centisome position: 62.85

GC content: 61.42

Gene sequence:

>1068_bases
ATGCAGGAGGAAGTTCGGCAGCTGATTGAAGAATTGCGCCACGCTGTGACGCGTCCGTGGGCGGTAATGGAGGTATGCGG
AGGCCAGACGCATGCGATTGCTTCTCTGGGGCTGGAGGAGTTGCTGCCTCCCGGCCTGCGCCTGATTCATGGCCCCGGCT
GTCCGGTCTGCGTTACGGCGGTGGAGTTGATTGACCAGGCCGTGGAATTAAGCCTGAGGCCCGGCGTGGTTTTGTGCAGC
TACGGGGATATGATGCGGGTGCCGGGCTCCCGCGGGGATTTGTTTTCCGCCAAGGCCGGGGGAGGGAACGTGTTTTTGAT
GTATTCTCCGCTGGAAGCGGTCGCTTATGCCGGAAGCCATCCGGATACGGAAGTGGTGTTTTTCGCCGTAGGTTTTGAGA
CGACGGCCCCGGCTACGGCTCTTGCCCTGCAGCAGGCCCGCATGCTGGGGTATGCCAATTTTTCCGTTCTCTGCGCCCAT
GTGCTGGTCCCCCCGGCTCTGGAATGGCTGATGGACCAGGATGAGGGAAGGCCGGACGCTTTTTTGGCTCCCGGCCATGT
CTGCGCCGTCACGGGGGAAATGGATTACGTGCGTTTGGCCGCCCGTTACCGGACGCCCATGGTGGTGACGGGGTTTGAGG
CTCCGGACCTGCTCCGCGGCATTCTGATGTGCGTCCGCCAGCTGGAAGCCGGGGAATATGTAGTGCGGAATGCGTACGGA
CGTTATGTGAAGCCCGGAGGGAACAGGGCGGCACAGGAAAGAATGAATGAAGTTTTTGAGCCGGAAGACCGCCGTTGGCG
CGGTCTGGGGCTGATTCCCGGCGGCGGCATGAGGCTGCGCCGTGAGTGGAATGACATGGATGCCGTTCTGCGTTTTGAAT
GCGGAAAGGGGAGGCCGGGAGCAGATGAAGCTTCCGGATGCCTGGCCGGGCAGGTGCTGAGGGGGCTGATTCGTCCTGGA
GAATGCCCTTTTTTCGGATCGTCCTGCACGCCGCTGGCCCCGCTGGGGGCTCCCATGGTGTCCGGGGAAGGGGCTTGCGC
CGCTTATTATCATTATAAAAGAAGTTGA

Upstream 100 bases:

>100_bases
CGAGGAGACCGCTCTTCAAACCCGCAGGGAAATGAGAGAAATTGTGGAAAATACGGATCCGCTGTAGGGAGGGGCGTTTT
CCGAATTCAATTAATGATTT

Downstream 100 bases:

>100_bases
TGCCATGTTTGAGTGTCCTGTTCCGGAGCCTGTTTCCGACCGTATCCAGATGGCTCATGGCGGCGGAGGCCGCTTGATGA
ATGAGCTGATCCGTTCCGTG

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQEEVRQLIEELRHAVTRPWAVMEVCGGQTHAIASLGLEELLPPGLRLIHGPGCPVCVTAVELIDQAVELSLRPGVVLCS
YGDMMRVPGSRGDLFSAKAGGGNVFLMYSPLEAVAYAGSHPDTEVVFFAVGFETTAPATALALQQARMLGYANFSVLCAH
VLVPPALEWLMDQDEGRPDAFLAPGHVCAVTGEMDYVRLAARYRTPMVVTGFEAPDLLRGILMCVRQLEAGEYVVRNAYG
RYVKPGGNRAAQERMNEVFEPEDRRWRGLGLIPGGGMRLRREWNDMDAVLRFECGKGRPGADEASGCLAGQVLRGLIRPG
ECPFFGSSCTPLAPLGAPMVSGEGACAAYYHYKRS

Sequences:

>Translated_355_residues
MQEEVRQLIEELRHAVTRPWAVMEVCGGQTHAIASLGLEELLPPGLRLIHGPGCPVCVTAVELIDQAVELSLRPGVVLCS
YGDMMRVPGSRGDLFSAKAGGGNVFLMYSPLEAVAYAGSHPDTEVVFFAVGFETTAPATALALQQARMLGYANFSVLCAH
VLVPPALEWLMDQDEGRPDAFLAPGHVCAVTGEMDYVRLAARYRTPMVVTGFEAPDLLRGILMCVRQLEAGEYVVRNAYG
RYVKPGGNRAAQERMNEVFEPEDRRWRGLGLIPGGGMRLRREWNDMDAVLRFECGKGRPGADEASGCLAGQVLRGLIRPG
ECPFFGSSCTPLAPLGAPMVSGEGACAAYYHYKRS
>Mature_355_residues
MQEEVRQLIEELRHAVTRPWAVMEVCGGQTHAIASLGLEELLPPGLRLIHGPGCPVCVTAVELIDQAVELSLRPGVVLCS
YGDMMRVPGSRGDLFSAKAGGGNVFLMYSPLEAVAYAGSHPDTEVVFFAVGFETTAPATALALQQARMLGYANFSVLCAH
VLVPPALEWLMDQDEGRPDAFLAPGHVCAVTGEMDYVRLAARYRTPMVVTGFEAPDLLRGILMCVRQLEAGEYVVRNAYG
RYVKPGGNRAAQERMNEVFEPEDRRWRGLGLIPGGGMRLRREWNDMDAVLRFECGKGRPGADEASGCLAGQVLRGLIRPG
ECPFFGSSCTPLAPLGAPMVSGEGACAAYYHYKRS

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=361, Percent_Identity=44.8753462603878, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 38447; Mature: 38447

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEEVRQLIEELRHAVTRPWAVMEVCGGQTHAIASLGLEELLPPGLRLIHGPGCPVCVTA
CCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCHHHHCCCCCEEEECCCCHHHHHH
VELIDQAVELSLRPGVVLCSYGDMMRVPGSRGDLFSAKAGGGNVFLMYSPLEAVAYAGSH
HHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCEEEECCCCCEEEEEECCHHHHHHCCCC
PDTEVVFFAVGFETTAPATALALQQARMLGYANFSVLCAHVLVPPALEWLMDQDEGRPDA
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
FLAPGHVCAVTGEMDYVRLAARYRTPMVVTGFEAPDLLRGILMCVRQLEAGEYVVRNAYG
EECCCCEEEEECCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCC
RYVKPGGNRAAQERMNEVFEPEDRRWRGLGLIPGGGMRLRREWNDMDAVLRFECGKGRPG
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHCCCCEEEEEECCCCCCC
ADEASGCLAGQVLRGLIRPGECPFFGSSCTPLAPLGAPMVSGEGACAAYYHYKRS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEEEECCC
>Mature Secondary Structure
MQEEVRQLIEELRHAVTRPWAVMEVCGGQTHAIASLGLEELLPPGLRLIHGPGCPVCVTA
CCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCHHHHCCCCCEEEECCCCHHHHHH
VELIDQAVELSLRPGVVLCSYGDMMRVPGSRGDLFSAKAGGGNVFLMYSPLEAVAYAGSH
HHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCEEEECCCCCEEEEEECCHHHHHHCCCC
PDTEVVFFAVGFETTAPATALALQQARMLGYANFSVLCAHVLVPPALEWLMDQDEGRPDA
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
FLAPGHVCAVTGEMDYVRLAARYRTPMVVTGFEAPDLLRGILMCVRQLEAGEYVVRNAYG
EECCCCEEEEECCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCC
RYVKPGGNRAAQERMNEVFEPEDRRWRGLGLIPGGGMRLRREWNDMDAVLRFECGKGRPG
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHCCCCEEEEEECCCCCCC
ADEASGCLAGQVLRGLIRPGECPFFGSSCTPLAPLGAPMVSGEGACAAYYHYKRS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]