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The map label for this gene is fabF [H]

Identifier: 187735820

GI number: 187735820

Start: 1604753

End: 1606000

Strand: Reverse

Name: fabF [H]

Synonym: Amuc_1327

Alternate gene names: 187735820

Gene position: 1606000-1604753 (Counterclockwise)

Preceding gene: 187735821

Following gene: 187735819

Centisome position: 60.28

GC content: 62.42

Gene sequence:

>1248_bases
ATGACCGACCGCAGAATTGTTATCACCGGCATCGGAGTGATCAGCCCCCTGGGCAATGATCTCGCATCCACCTGGGAAGC
CATGAAGGCTGGCCGCAGCGGCATTGACACCATCAAATCCATGGATGTTACCGGCTACTCCACGAAAATCGCCGGTGAAG
TCAAGGATTTCGATCCCGCCCCGTACTTCAAGACGCCCAAGGACGCCCGCCGCGTGGACCGCTTCACGCACTTTGCCATG
GGCGCTGCCGGAATGGCTCTCAAGGATTCCGGGCTGGATCTGGAAGCGGAGGACAAAACCCGCATCGGCGTCATGGTGGG
CAGCGGCATCGGCGGCCTCGGCACGCTGGAAAGCCAGCATGCCACGCTTCTTTCCAAGGGGCCTGCCCGCGTGTCCCCCT
TCATGATCCCGTACATGATCAGCAACATTGCCTCCGGCCTCATCTCCATGGAATACGGCCTCGGCGGTCCGAACATGTCC
ATCGTCACGGCCTGCGCCACCTCCAACCACAACATCGGGGAAGCCTGGCGCATCATGAAATTCGGGGATGCCGACGTCAT
GGTCTGCGGCGGAGCGGAAGCTACCATCCTGCCCACGGGCGTGGCCGGGTTCAGCAACATGAAAGCCCTCAGCTCCCGCA
ATGACGAGCCCCAGCGGGCCTCCCGCCCGTACGACGTGGACCGCGACGGCTTCGTCATGGGCGAAGGCGCCGGCGTTGTC
ATTCTGGAAACGCTGGAACACGCCCAGAAGCGCGGCGCAAAAATTTACGGGGAACTCGTCGGCTACGGCATCTCCGCGGA
CGCCTACCACCTCACCGCCCCGGACCCGGAAGGCCGCGGCGCCGCCCGCTGCATGAAGATGGCTCTGGAACACGCGGGAA
TGAAGCCGGAAGACATTGACTACGTCAACACGCACGGCACCTCCACCCCGCTGGGCGACATCTGCGAAATCAAGGCCATC
AAGGCCGTTTTCGGCGACCACGCTAAAAACGGGCTGCTTATCAGCTCCACCAAATCCATGACCGGCCACCTCCTGGGCGC
CGCGGGAGGCGTGGAACTGGCCGCCTGCCTGATGGCCATGCAGGACAACATCATCCCGCCCACCATCAACGTGGACAACC
AGGATCCGGAATGCGACCTGGACTGCGTGCCCAATAAGGCCCGTGAAACCAGGGTGGACGCCGTCTTGAGCAATTCCTTC
GGCTTCGGGGGGCATAACTCCTCCGTCATCGTGAAACGATTCGCCTGA

Upstream 100 bases:

>100_bases
CCTGTTTCCCCCGTGCCGGGAAACAGGGGGGATTAGCTTGACTTTCCCGTAATGTCGCCTATTCTGGTTCAAGCATTATT
TGCAACCACTCACACTTATT

Downstream 100 bases:

>100_bases
CCCTTTCAGGCCTCTCCTTTCCGGCGGAAGCGCTGATGTTTGCGGCCACCGCAGCCATCGCGCTTCCGCTTTTTTCATTT
AAAAGCCATGCCCGCCAAAA

Product: 3-oxoacyl-(acyl-carrier-protein) synthase 2

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTDRRIVITGIGVISPLGNDLASTWEAMKAGRSGIDTIKSMDVTGYSTKIAGEVKDFDPAPYFKTPKDARRVDRFTHFAM
GAAGMALKDSGLDLEAEDKTRIGVMVGSGIGGLGTLESQHATLLSKGPARVSPFMIPYMISNIASGLISMEYGLGGPNMS
IVTACATSNHNIGEAWRIMKFGDADVMVCGGAEATILPTGVAGFSNMKALSSRNDEPQRASRPYDVDRDGFVMGEGAGVV
ILETLEHAQKRGAKIYGELVGYGISADAYHLTAPDPEGRGAARCMKMALEHAGMKPEDIDYVNTHGTSTPLGDICEIKAI
KAVFGDHAKNGLLISSTKSMTGHLLGAAGGVELAACLMAMQDNIIPPTINVDNQDPECDLDCVPNKARETRVDAVLSNSF
GFGGHNSSVIVKRFA

Sequences:

>Translated_415_residues
MTDRRIVITGIGVISPLGNDLASTWEAMKAGRSGIDTIKSMDVTGYSTKIAGEVKDFDPAPYFKTPKDARRVDRFTHFAM
GAAGMALKDSGLDLEAEDKTRIGVMVGSGIGGLGTLESQHATLLSKGPARVSPFMIPYMISNIASGLISMEYGLGGPNMS
IVTACATSNHNIGEAWRIMKFGDADVMVCGGAEATILPTGVAGFSNMKALSSRNDEPQRASRPYDVDRDGFVMGEGAGVV
ILETLEHAQKRGAKIYGELVGYGISADAYHLTAPDPEGRGAARCMKMALEHAGMKPEDIDYVNTHGTSTPLGDICEIKAI
KAVFGDHAKNGLLISSTKSMTGHLLGAAGGVELAACLMAMQDNIIPPTINVDNQDPECDLDCVPNKARETRVDAVLSNSF
GFGGHNSSVIVKRFA
>Mature_414_residues
TDRRIVITGIGVISPLGNDLASTWEAMKAGRSGIDTIKSMDVTGYSTKIAGEVKDFDPAPYFKTPKDARRVDRFTHFAMG
AAGMALKDSGLDLEAEDKTRIGVMVGSGIGGLGTLESQHATLLSKGPARVSPFMIPYMISNIASGLISMEYGLGGPNMSI
VTACATSNHNIGEAWRIMKFGDADVMVCGGAEATILPTGVAGFSNMKALSSRNDEPQRASRPYDVDRDGFVMGEGAGVVI
LETLEHAQKRGAKIYGELVGYGISADAYHLTAPDPEGRGAARCMKMALEHAGMKPEDIDYVNTHGTSTPLGDICEIKAIK
AVFGDHAKNGLLISSTKSMTGHLLGAAGGVELAACLMAMQDNIIPPTINVDNQDPECDLDCVPNKARETRVDAVLSNSFG
FGGHNSSVIVKRFA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=45.8033573141487, Blast_Score=358, Evalue=5e-99,
Organism=Homo sapiens, GI223972627, Length=163, Percent_Identity=52.1472392638037, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI41872631, Length=421, Percent_Identity=24.7030878859857, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787337, Length=415, Percent_Identity=53.0120481927711, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1788663, Length=419, Percent_Identity=37.9474940334129, Blast_Score=258, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=37.5, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI71983535, Length=260, Percent_Identity=43.8461538461538, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI212642053, Length=375, Percent_Identity=26.4, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=417, Percent_Identity=23.9808153477218, Blast_Score=105, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=36.4864864864865, Blast_Score=275, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24644341, Length=420, Percent_Identity=42.8571428571429, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI19920632, Length=369, Percent_Identity=27.10027100271, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI221330659, Length=369, Percent_Identity=27.10027100271, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24581345, Length=370, Percent_Identity=24.0540540540541, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43822; Mature: 43690

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRRIVITGIGVISPLGNDLASTWEAMKAGRSGIDTIKSMDVTGYSTKIAGEVKDFDPA
CCCCEEEEEECCHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCCCCC
PYFKTPKDARRVDRFTHFAMGAAGMALKDSGLDLEAEDKTRIGVMVGSGIGGLGTLESQH
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCHH
ATLLSKGPARVSPFMIPYMISNIASGLISMEYGLGGPNMSIVTACATSNHNIGEAWRIMK
HHHHCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCCCCCCHHEEEEE
FGDADVMVCGGAEATILPTGVAGFSNMKALSSRNDEPQRASRPYDVDRDGFVMGEGAGVV
ECCCCEEEECCCCCEEEECCCCCCHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCCCEE
ILETLEHAQKRGAKIYGELVGYGISADAYHLTAPDPEGRGAARCMKMALEHAGMKPEDID
EEHHHHHHHHCCHHEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
YVNTHGTSTPLGDICEIKAIKAVFGDHAKNGLLISSTKSMTGHLLGAAGGVELAACLMAM
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHEEECCCHHHHHHHHHHH
QDNIIPPTINVDNQDPECDLDCVPNKARETRVDAVLSNSFGFGGHNSSVIVKRFA
HCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TDRRIVITGIGVISPLGNDLASTWEAMKAGRSGIDTIKSMDVTGYSTKIAGEVKDFDPA
CCCEEEEEECCHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCCCCCC
PYFKTPKDARRVDRFTHFAMGAAGMALKDSGLDLEAEDKTRIGVMVGSGIGGLGTLESQH
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCHH
ATLLSKGPARVSPFMIPYMISNIASGLISMEYGLGGPNMSIVTACATSNHNIGEAWRIMK
HHHHCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCCCCCCHHEEEEE
FGDADVMVCGGAEATILPTGVAGFSNMKALSSRNDEPQRASRPYDVDRDGFVMGEGAGVV
ECCCCEEEECCCCCEEEECCCCCCHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCCCEE
ILETLEHAQKRGAKIYGELVGYGISADAYHLTAPDPEGRGAARCMKMALEHAGMKPEDID
EEHHHHHHHHCCHHEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
YVNTHGTSTPLGDICEIKAIKAVFGDHAKNGLLISSTKSMTGHLLGAAGGVELAACLMAM
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHEEECCCHHHHHHHHHHH
QDNIIPPTINVDNQDPECDLDCVPNKARETRVDAVLSNSFGFGGHNSSVIVKRFA
HCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]