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The map label for this gene is asd [H]

Identifier: 187735759

GI number: 187735759

Start: 1525615

End: 1526625

Strand: Reverse

Name: asd [H]

Synonym: Amuc_1265

Alternate gene names: 187735759

Gene position: 1526625-1525615 (Counterclockwise)

Preceding gene: 187735760

Following gene: 187735758

Centisome position: 57.3

GC content: 57.17

Gene sequence:

>1011_bases
ATGAACCAAGCACCCCATGTTGCCATCGTCGGCGCCACCGGAGCGGTGGGCGTTGAAATCCTGTCCTGCCTGGAAACACG
CAATTTTCCCGTAGGTTCCCTGAAGCTTCTGGCCTCCGCCCGGTCCGCCGGAAAACAGGTCGCTTTCCGTGGGAAAATGC
TGACTGTAGAAGAATTGACGGAAAAATCCTTTGATGGGGTGGATATCGCCCTGTTCAGCGCAGGCGGAGGAATTTCCCTG
AAATTCGCTCCTATCGCAGCGGCTGCGGGCTGTGTGGTCATTGACAATTCCTCTGCCTTCCGGCAGGAGCCGGACGTGCC
CCTGGTGGTGCCGGAAATCAATCCGGAAGCGGCCTTCAACCACCCCCGCAATATTATCGCCAACCCGAACTGCACCACCA
TCATTACGCTGATGGCCCTCTTCCCTCTGCATCAGCGTTTCGGGTTGAAAACCGTCATCGCCTCCAGTTATCAGGCGGTT
TCCGGCAGCGGCCAGCACGGCATTGCGGAACTGGAAACCCAGGTGCGCGCCGTAGTGGACGGCCACCCCGTAGTGAAAAA
TGTTTATCCCCACCAGATAGCCTTCAATCTTCTTCCCCAGATCGATTCCTTTACGGAAAACGGCTATACCAAGGAAGAGC
TTAAGATGCTTAATGAAGGCCGTAAAATTCTTTCCCTGCCCGAACTCAAGGTAACATGCACCTGCGTGCGCGTGCCCGTT
TACCGTTCCCATTCCATCTCCGTTACCGCCCAGTTTGAAAAACCTGTGGACTTGGAAACTGCCCGCAGCGCCTATGAAGG
CAAACCCGGAGTCGCCCTGATGGACAACCCAGCGGAGGGCGTGTGGCCCACCCCGCTGGACAGCACCAACGGAGATACCT
GCTACGTAGGGCGCATGCGCATGGACATGGCGATTGACAATGCCCTGACTCTCTGGGTCGTGGGCGATCAGGTCCGAAAA
GGGGCCGCACTCAACGCCGTACAAATCGCGGAATTGCTGGTCAACCGCTGA

Upstream 100 bases:

>100_bases
TCATTTTTAAGCCTGAAGGCTTGCAATCGTATTGCCATATGACCGGGCTGCCGTATAATGGGGGCGAACGGAAAATATCC
GTCATTTTCTGACAACAATC

Downstream 100 bases:

>100_bases
CCTGTTTCCTCCACACCCCGCACCTATTCCATAACGCCATGTGTGAACAATCACTGAACGACTACATCACAGAACAATGC
GCCCTGATTGACGCAGCGCT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNQAPHVAIVGATGAVGVEILSCLETRNFPVGSLKLLASARSAGKQVAFRGKMLTVEELTEKSFDGVDIALFSAGGGISL
KFAPIAAAAGCVVIDNSSAFRQEPDVPLVVPEINPEAAFNHPRNIIANPNCTTIITLMALFPLHQRFGLKTVIASSYQAV
SGSGQHGIAELETQVRAVVDGHPVVKNVYPHQIAFNLLPQIDSFTENGYTKEELKMLNEGRKILSLPELKVTCTCVRVPV
YRSHSISVTAQFEKPVDLETARSAYEGKPGVALMDNPAEGVWPTPLDSTNGDTCYVGRMRMDMAIDNALTLWVVGDQVRK
GAALNAVQIAELLVNR

Sequences:

>Translated_336_residues
MNQAPHVAIVGATGAVGVEILSCLETRNFPVGSLKLLASARSAGKQVAFRGKMLTVEELTEKSFDGVDIALFSAGGGISL
KFAPIAAAAGCVVIDNSSAFRQEPDVPLVVPEINPEAAFNHPRNIIANPNCTTIITLMALFPLHQRFGLKTVIASSYQAV
SGSGQHGIAELETQVRAVVDGHPVVKNVYPHQIAFNLLPQIDSFTENGYTKEELKMLNEGRKILSLPELKVTCTCVRVPV
YRSHSISVTAQFEKPVDLETARSAYEGKPGVALMDNPAEGVWPTPLDSTNGDTCYVGRMRMDMAIDNALTLWVVGDQVRK
GAALNAVQIAELLVNR
>Mature_336_residues
MNQAPHVAIVGATGAVGVEILSCLETRNFPVGSLKLLASARSAGKQVAFRGKMLTVEELTEKSFDGVDIALFSAGGGISL
KFAPIAAAAGCVVIDNSSAFRQEPDVPLVVPEINPEAAFNHPRNIIANPNCTTIITLMALFPLHQRFGLKTVIASSYQAV
SGSGQHGIAELETQVRAVVDGHPVVKNVYPHQIAFNLLPQIDSFTENGYTKEELKMLNEGRKILSLPELKVTCTCVRVPV
YRSHSISVTAQFEKPVDLETARSAYEGKPGVALMDNPAEGVWPTPLDSTNGDTCYVGRMRMDMAIDNALTLWVVGDQVRK
GAALNAVQIAELLVNR

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=340, Percent_Identity=36.1764705882353, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=26.1971830985915, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320362, Length=384, Percent_Identity=28.90625, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36062; Mature: 36062

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAPHVAIVGATGAVGVEILSCLETRNFPVGSLKLLASARSAGKQVAFRGKMLTVEELT
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCEEEHHHHH
EKSFDGVDIALFSAGGGISLKFAPIAAAAGCVVIDNSSAFRQEPDVPLVVPEINPEAAFN
HCCCCCCEEEEEECCCCCEEEEECHHHHCCEEEEECCHHHCCCCCCCEEEECCCCCCCCC
HPRNIIANPNCTTIITLMALFPLHQRFGLKTVIASSYQAVSGSGQHGIAELETQVRAVVD
CCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCC
GHPVVKNVYPHQIAFNLLPQIDSFTENGYTKEELKMLNEGRKILSLPELKVTCTCVRVPV
CCCHHHCCCCHHHHHHHHHCHHHHHCCCCCHHHHHHHHCCCCEEECCCCEEEEEEEEEEE
YRSHSISVTAQFEKPVDLETARSAYEGKPGVALMDNPAEGVWPTPLDSTNGDTCYVGRMR
EECCEEEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEE
MDMAIDNALTLWVVGDQVRKGAALNAVQIAELLVNR
EEEEECCEEEEEEECCHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNQAPHVAIVGATGAVGVEILSCLETRNFPVGSLKLLASARSAGKQVAFRGKMLTVEELT
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCEEEHHHHH
EKSFDGVDIALFSAGGGISLKFAPIAAAAGCVVIDNSSAFRQEPDVPLVVPEINPEAAFN
HCCCCCCEEEEEECCCCCEEEEECHHHHCCEEEEECCHHHCCCCCCCEEEECCCCCCCCC
HPRNIIANPNCTTIITLMALFPLHQRFGLKTVIASSYQAVSGSGQHGIAELETQVRAVVD
CCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHCC
GHPVVKNVYPHQIAFNLLPQIDSFTENGYTKEELKMLNEGRKILSLPELKVTCTCVRVPV
CCCHHHCCCCHHHHHHHHHCHHHHHCCCCCHHHHHHHHCCCCEEECCCCEEEEEEEEEEE
YRSHSISVTAQFEKPVDLETARSAYEGKPGVALMDNPAEGVWPTPLDSTNGDTCYVGRMR
EECCEEEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEE
MDMAIDNALTLWVVGDQVRKGAALNAVQIAELLVNR
EEEEECCEEEEEEECCHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]