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The map label for this gene is ltaE [H]

Identifier: 187735656

GI number: 187735656

Start: 1393663

End: 1394700

Strand: Direct

Name: ltaE [H]

Synonym: Amuc_1162

Alternate gene names: 187735656

Gene position: 1393663-1394700 (Clockwise)

Preceding gene: 187735654

Following gene: 187735657

Centisome position: 52.31

GC content: 58.48

Gene sequence:

>1038_bases
ATGATTCTTTTCAACTGTGATTACAGTGAAGGCGCCCATGCGGATATTCTCCGCAGAATGGCGGAAACGAATATGGAGCA
GACTGCCGGTTACGGGGAGGACCCCTATTGCGACCAGGCCCGGAAGCTGATTGCCGGCTTGTGCGGCAGAACGGATCTGG
ATATCCATTTCCTTATCGGCGGGACCCAGACCAATTTCACGGTAATTGCGGCGGCGCTGCGTCCCCATCAATGCGTGCTG
TGCGCGGACACGGGCCATATCAATGTGCACGAGTCGGGAGCCGTTGAGGCTTGCGGACACAAGGTTTCCGCTATTCCTTC
CCCGGATGGGAAGCTGACGGCCCGGCAAATTGAGGAGGCGTGGCACGCCCACTGGGATGACGAGACCCGTGAGCATATGC
CTCAGCCCCGGATGGTTTATATTTCCCAGCCGACCGAATTGGGCACCATTTATTCCAGAAAGGAACTTCAGGAAATTTCC
GGAGTCTGCCGCCGGCGGGGGCTGTATTTGTATATGGACGGAGCACGCCTCGGCTACGGCTTGTGCGATGAGGACAATGA
CCTGGATTTGCCGGCGATTGCCTCCCTTTGCGATGCTTTTTACATCGGCGGCACGAAGGTCGGCGCTCTGTTTGGTGAAG
CCCTGGTTCTGCGGCATGAGGCCCTGAAGGAGGATTTCCGTTACATCGCCAAGCAGAAGGGCGGCCGTCTTGCGAAAGGG
CGGCTTCTGGGCATTCAGTTCCTGGAGCTGTTCCGCGACGGCCTTTATTTCCGGCTGGGCGCCCATGCGGACCGCCTGGC
TGTGATGCTGCGGGATTTTTGCCGTTCCAGAGGGCTGGCGCTTCCCTTTTCCAGCGGAACGAACCAACAGTTTGTCACGA
TGCCCGATTCCGTTCTGGAGGAGCTGGGGAGGAAATACGGTTTTGCCTATTTGCGCCGGGAGGATGAAACCCACAGCACG
GTGCGCTTCTGCACGAGCTGGGCCACCCGAGAGGAAGACGTACGGGAATTGATGGCGGATATCGCCCGCCTGTGCTGA

Upstream 100 bases:

>100_bases
TGGAGTTTCCAGCAGCGCTGTTCCGGTTCCGGTGTATTTTTCATATTCCTTTACATCAAAGGTTCCGGGGGATATGGTCC
CCGCGTTTTTCAGCAAGGCA

Downstream 100 bases:

>100_bases
AATTTCCCTCCGTCCGGCAATGCCGGGAAACTGCGGAAAGGGACGTTCCCCCATTCGTTTGCGGAAAAGCATTTTTGTCT
TTCCGGGAGGAACCTGTTGA

Product: Threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MILFNCDYSEGAHADILRRMAETNMEQTAGYGEDPYCDQARKLIAGLCGRTDLDIHFLIGGTQTNFTVIAAALRPHQCVL
CADTGHINVHESGAVEACGHKVSAIPSPDGKLTARQIEEAWHAHWDDETREHMPQPRMVYISQPTELGTIYSRKELQEIS
GVCRRRGLYLYMDGARLGYGLCDEDNDLDLPAIASLCDAFYIGGTKVGALFGEALVLRHEALKEDFRYIAKQKGGRLAKG
RLLGIQFLELFRDGLYFRLGAHADRLAVMLRDFCRSRGLALPFSSGTNQQFVTMPDSVLEELGRKYGFAYLRREDETHST
VRFCTSWATREEDVRELMADIARLC

Sequences:

>Translated_345_residues
MILFNCDYSEGAHADILRRMAETNMEQTAGYGEDPYCDQARKLIAGLCGRTDLDIHFLIGGTQTNFTVIAAALRPHQCVL
CADTGHINVHESGAVEACGHKVSAIPSPDGKLTARQIEEAWHAHWDDETREHMPQPRMVYISQPTELGTIYSRKELQEIS
GVCRRRGLYLYMDGARLGYGLCDEDNDLDLPAIASLCDAFYIGGTKVGALFGEALVLRHEALKEDFRYIAKQKGGRLAKG
RLLGIQFLELFRDGLYFRLGAHADRLAVMLRDFCRSRGLALPFSSGTNQQFVTMPDSVLEELGRKYGFAYLRREDETHST
VRFCTSWATREEDVRELMADIARLC
>Mature_345_residues
MILFNCDYSEGAHADILRRMAETNMEQTAGYGEDPYCDQARKLIAGLCGRTDLDIHFLIGGTQTNFTVIAAALRPHQCVL
CADTGHINVHESGAVEACGHKVSAIPSPDGKLTARQIEEAWHAHWDDETREHMPQPRMVYISQPTELGTIYSRKELQEIS
GVCRRRGLYLYMDGARLGYGLCDEDNDLDLPAIASLCDAFYIGGTKVGALFGEALVLRHEALKEDFRYIAKQKGGRLAKG
RLLGIQFLELFRDGLYFRLGAHADRLAVMLRDFCRSRGLALPFSSGTNQQFVTMPDSVLEELGRKYGFAYLRREDETHST
VRFCTSWATREEDVRELMADIARLC

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=306, Percent_Identity=26.1437908496732, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38739; Mature: 38739

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFNCDYSEGAHADILRRMAETNMEQTAGYGEDPYCDQARKLIAGLCGRTDLDIHFLIG
CEEEECCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEE
GTQTNFTVIAAALRPHQCVLCADTGHINVHESGAVEACGHKVSAIPSPDGKLTARQIEEA
CCCCCCEEEEEECCCCEEEEEECCCEEEECCCCCHHHCCCCCCCCCCCCCCHHHHHHHHH
WHAHWDDETREHMPQPRMVYISQPTELGTIYSRKELQEISGVCRRRGLYLYMDGARLGYG
HHCCCCCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
LCDEDNDLDLPAIASLCDAFYIGGTKVGALFGEALVLRHEALKEDFRYIAKQKGGRLAKG
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RLLGIQFLELFRDGLYFRLGAHADRLAVMLRDFCRSRGLALPFSSGTNQQFVTMPDSVLE
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCHHHHH
ELGRKYGFAYLRREDETHSTVRFCTSWATREEDVRELMADIARLC
HHHHHHCCHHEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MILFNCDYSEGAHADILRRMAETNMEQTAGYGEDPYCDQARKLIAGLCGRTDLDIHFLIG
CEEEECCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEE
GTQTNFTVIAAALRPHQCVLCADTGHINVHESGAVEACGHKVSAIPSPDGKLTARQIEEA
CCCCCCEEEEEECCCCEEEEEECCCEEEECCCCCHHHCCCCCCCCCCCCCCHHHHHHHHH
WHAHWDDETREHMPQPRMVYISQPTELGTIYSRKELQEISGVCRRRGLYLYMDGARLGYG
HHCCCCCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
LCDEDNDLDLPAIASLCDAFYIGGTKVGALFGEALVLRHEALKEDFRYIAKQKGGRLAKG
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RLLGIQFLELFRDGLYFRLGAHADRLAVMLRDFCRSRGLALPFSSGTNQQFVTMPDSVLE
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCHHHHH
ELGRKYGFAYLRREDETHSTVRFCTSWATREEDVRELMADIARLC
HHHHHHCCHHEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]