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The map label for this gene is tadA [H]

Identifier: 187735588

GI number: 187735588

Start: 1304612

End: 1305157

Strand: Reverse

Name: tadA [H]

Synonym: Amuc_1093

Alternate gene names: 187735588

Gene position: 1305157-1304612 (Counterclockwise)

Preceding gene: 187735591

Following gene: 187735587

Centisome position: 48.99

GC content: 59.52

Gene sequence:

>546_bases
ATGATAACCTCCGTAATGATGGAAATGCCCGGTTCGGACGAATGGTTCATGCGCCAAGCCATGAAAGAATCCAGAAAGGC
CCTCGTGAAAGGGGAAGTGCCTGTTGGAGCCATTGTGGTGAAGGATGGCCGCGTGATCGGCCGGGGCTGGAACCAGGTGG
AGACGCTCAAGGATGCTACGGCCCATGCGGAGATGATTGCCCTGACGGCGGCACAGGAGGCTTTGGGCGACTGGAGGCTG
GAAGGCTGCACCCTGTATGTCACCAAGGAGCCGTGCCCCATGTGCGCAGGAGCTATCGTCCACTGCCGTCCGGACCGCGT
CGTTTTCGGCTGCCCGGATGCAAAAACCGGGGCTGCGGGGGGCTGGATCAATCTGCTGGATTCCAATCCGCCCCTGAACC
ATAAGTGCGAGGTGCGTCCCGGCGTACTGGGAGACGAGTGCCTGCTTCATCTCCAGGAGTTTTTCCGTGCGGCGCGTCTG
GCGGCAAAAGAACGGAAAAAATTGTCTGCGCGTCTTTCTTCCCCTCCGGATGAAAACGGGGAATGA

Upstream 100 bases:

>100_bases
GCATTCATCCCCACCCCTTTCCGCGGCATGGCGCACTTACCGTATAAAACACAATAAGAATCTTCCAGAAAGAGCTTGCC
AGAACCGCGCCGCCCGGTCC

Downstream 100 bases:

>100_bases
AGTCCGGAATAAAACACTTTGCATTTGCCAAAGCAGCAGAGTCACGGCAAGCTAGCGGGACTATGGAACGCCGGAACGAC
AATGAGACTGCGGAAGGAAC

Product: CMP/dCMP deaminase zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MITSVMMEMPGSDEWFMRQAMKESRKALVKGEVPVGAIVVKDGRVIGRGWNQVETLKDATAHAEMIALTAAQEALGDWRL
EGCTLYVTKEPCPMCAGAIVHCRPDRVVFGCPDAKTGAAGGWINLLDSNPPLNHKCEVRPGVLGDECLLHLQEFFRAARL
AAKERKKLSARLSSPPDENGE

Sequences:

>Translated_181_residues
MITSVMMEMPGSDEWFMRQAMKESRKALVKGEVPVGAIVVKDGRVIGRGWNQVETLKDATAHAEMIALTAAQEALGDWRL
EGCTLYVTKEPCPMCAGAIVHCRPDRVVFGCPDAKTGAAGGWINLLDSNPPLNHKCEVRPGVLGDECLLHLQEFFRAARL
AAKERKKLSARLSSPPDENGE
>Mature_181_residues
MITSVMMEMPGSDEWFMRQAMKESRKALVKGEVPVGAIVVKDGRVIGRGWNQVETLKDATAHAEMIALTAAQEALGDWRL
EGCTLYVTKEPCPMCAGAIVHCRPDRVVFGCPDAKTGAAGGWINLLDSNPPLNHKCEVRPGVLGDECLLHLQEFFRAARL
AAKERKKLSARLSSPPDENGE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=154, Percent_Identity=33.7662337662338, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI145693172, Length=162, Percent_Identity=48.1481481481481, Blast_Score=152, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=44.7916666666667, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17541138, Length=113, Percent_Identity=37.1681415929204, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555996, Length=104, Percent_Identity=38.4615384615385, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=164, Percent_Identity=32.9268292682927, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355527, Length=158, Percent_Identity=32.2784810126582, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19772; Mature: 19772

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSVMMEMPGSDEWFMRQAMKESRKALVKGEVPVGAIVVKDGRVIGRGWNQVETLKDAT
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCHHHHHHHHH
AHAEMIALTAAQEALGDWRLEGCTLYVTKEPCPMCAGAIVHCRPDRVVFGCPDAKTGAAG
HHHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCCC
GWINLLDSNPPLNHKCEVRPGVLGDECLLHLQEFFRAARLAAKERKKLSARLSSPPDENG
CEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
E
C
>Mature Secondary Structure
MITSVMMEMPGSDEWFMRQAMKESRKALVKGEVPVGAIVVKDGRVIGRGWNQVETLKDAT
CCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCHHHHHHHHH
AHAEMIALTAAQEALGDWRLEGCTLYVTKEPCPMCAGAIVHCRPDRVVFGCPDAKTGAAG
HHHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCCC
GWINLLDSNPPLNHKCEVRPGVLGDECLLHLQEFFRAARLAAKERKKLSARLSSPPDENG
CEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]