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The map label for this gene is coaX

Identifier: 187735475

GI number: 187735475

Start: 1164679

End: 1165407

Strand: Direct

Name: coaX

Synonym: Amuc_0974

Alternate gene names: 187735475

Gene position: 1164679-1165407 (Clockwise)

Preceding gene: 187735474

Following gene: 187735476

Centisome position: 43.72

GC content: 60.91

Gene sequence:

>729_bases
GTGACCTATCTTCTGATTGACAATTCCAACACACGCACCAAATTCGTGCTCTCTTCGCCGGAAGCCCTGTTGCCGGAACG
GTATATGGTTCCCACCCGGGAGGTGAGCGGGGAACGGCTGGACGAGGTGCTGGCCGGCGTTCGTTATGATGCCGCCGTGG
TGTGTTCCGTCGTGCCGCGCGTGGCGGAAGAACTGAAAAACTGGATCGTCAAACCGTGCCATTTCCTTTCCTGCGATTCC
CGGCTGGGCGTGGGCATCGACTATCCCCACCCGCGCCAGATAGGGGCCGACAGGCTGGCGAATGCCGTAGGAGCCGCGGC
CTATTACGGGTATCCTTGCGTTGTGGTGGACTTTGGCACCGCCGTGACTTTTGACGTGATCGGGCCCCAATGCACCTACA
TGGGCGGCGTTATTGCGCCGGGGCTTGCCAGCATGGGGGATTACCTGGAGCGCAATACGGCGCTTCTTCCCGCCATTGAC
CCCCAGGAGCCGTCCCGTGTCATTGGAACTAGCACAGTAGAGGCCATGCAATCCGGCGCCGTGTACGGTTATCGGGGGCT
GGTGAAGGAAATTCTGGCCCGGCTGGAAGGTGAGCTGGGCGTGCGTCCGGCCGTGGTTGCTACGGGAGGGGATGCAGCTC
TGATCGCCAGGGGAGTGGAGCGCATTGACCATGTGGACCCTGACATTACGTTGAACGGCTTGCGCATAGCCGCCGGACTG
AATCTTTAA

Upstream 100 bases:

>100_bases
GCATGCATGAAAACCTGCTGCGGGCCGGGATGACCGGAGGAAGCGGCAGAATAGCGGATTTGGCCTTGAAACTGGCGGAG
GAACATACTAACTGATTCCC

Downstream 100 bases:

>100_bases
AGAACGGCCAAAATCGGCTGGAAACCTGCTGCTTCCGGCTCCGTGGCCGGATGACGCATAAAAACTCATAAATAGGTGTT
GCAAATGGCGCATACCCCAT

Product: transcriptional acitvator, Baf family

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTYLLIDNSNTRTKFVLSSPEALLPERYMVPTREVSGERLDEVLAGVRYDAAVVCSVVPRVAEELKNWIVKPCHFLSCDS
RLGVGIDYPHPRQIGADRLANAVGAAAYYGYPCVVVDFGTAVTFDVIGPQCTYMGGVIAPGLASMGDYLERNTALLPAID
PQEPSRVIGTSTVEAMQSGAVYGYRGLVKEILARLEGELGVRPAVVATGGDAALIARGVERIDHVDPDITLNGLRIAAGL
NL

Sequences:

>Translated_242_residues
MTYLLIDNSNTRTKFVLSSPEALLPERYMVPTREVSGERLDEVLAGVRYDAAVVCSVVPRVAEELKNWIVKPCHFLSCDS
RLGVGIDYPHPRQIGADRLANAVGAAAYYGYPCVVVDFGTAVTFDVIGPQCTYMGGVIAPGLASMGDYLERNTALLPAID
PQEPSRVIGTSTVEAMQSGAVYGYRGLVKEILARLEGELGVRPAVVATGGDAALIARGVERIDHVDPDITLNGLRIAAGL
NL
>Mature_241_residues
TYLLIDNSNTRTKFVLSSPEALLPERYMVPTREVSGERLDEVLAGVRYDAAVVCSVVPRVAEELKNWIVKPCHFLSCDSR
LGVGIDYPHPRQIGADRLANAVGAAAYYGYPCVVVDFGTAVTFDVIGPQCTYMGGVIAPGLASMGDYLERNTALLPAIDP
QEPSRVIGTSTVEAMQSGAVYGYRGLVKEILARLEGELGVRPAVVATGGDAALIARGVERIDHVDPDITLNGLRIAAGLN
L

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_AKKM8 (B2UQS1)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877587.1
- ProteinModelPortal:   B2UQS1
- SMR:   B2UQS1
- GeneID:   6274172
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0974
- HOGENOM:   HBG634537
- OMA:   YLERNTA
- ProtClustDB:   CLSK2337871
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 25877; Mature: 25746

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: ACT_SITE 97-97 BINDING 88-88 BINDING 120-120 BINDING 172-172

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLLIDNSNTRTKFVLSSPEALLPERYMVPTREVSGERLDEVLAGVRYDAAVVCSVVPR
CEEEEEECCCCEEEEEECCCHHHCCCCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHH
VAEELKNWIVKPCHFLSCDSRLGVGIDYPHPRQIGADRLANAVGAAAYYGYPCVVVDFGT
HHHHHHHHHHCCHHEECCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHCCCCEEEEECCC
AVTFDVIGPQCTYMGGVIAPGLASMGDYLERNTALLPAIDPQEPSRVIGTSTVEAMQSGA
EEEEECCCCCHHHCCCHHHCCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHCCC
VYGYRGLVKEILARLEGELGVRPAVVATGGDAALIARGVERIDHVDPDITLNGLRIAAGL
CHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEECCEEEEECC
NL
CC
>Mature Secondary Structure 
TYLLIDNSNTRTKFVLSSPEALLPERYMVPTREVSGERLDEVLAGVRYDAAVVCSVVPR
EEEEEECCCCEEEEEECCCHHHCCCCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHH
VAEELKNWIVKPCHFLSCDSRLGVGIDYPHPRQIGADRLANAVGAAAYYGYPCVVVDFGT
HHHHHHHHHHCCHHEECCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHCCCCEEEEECCC
AVTFDVIGPQCTYMGGVIAPGLASMGDYLERNTALLPAIDPQEPSRVIGTSTVEAMQSGA
EEEEECCCCCHHHCCCHHHCCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHCCC
VYGYRGLVKEILARLEGELGVRPAVVATGGDAALIARGVERIDHVDPDITLNGLRIAAGL
CHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEECCEEEEECC
NL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA