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The map label for this gene is ppnK [H]

Identifier: 187735425

GI number: 187735425

Start: 1105799

End: 1106683

Strand: Direct

Name: ppnK [H]

Synonym: Amuc_0924

Alternate gene names: 187735425

Gene position: 1105799-1106683 (Clockwise)

Preceding gene: 187735421

Following gene: 187735426

Centisome position: 41.51

GC content: 62.82

Gene sequence:

>885_bases
ATGATCTCCCGCATGAATCCTTCCAAGGTAATCGGCCTGGTCGCTCTGGCGGAAAAACCGGGACTGGGGGAAGCGTTGCG
CATCATGCGCCGGGAACTTTCCCGCCACGGGCTGGGCTCCTGCGTCATTGAAACGCCGGATGCTCTGGAACGGGCTATCG
GACGGTGCGGCATGCTGGTGACCTTCGGAGGGGACGGTACCATGCTGACCGTCTCTTCTCTGGCGGCCATGCACCGCGTT
CCCCTGGCGGGAGTGAACCTGGGCCGGCTGGGGTTCATGACCACCTGTTCCGTGCAGGAACTGCCGCTTCTGGCGTATGC
CCTTCAGGAAGGTTCCTACCTGACGGATGAACGTTCCATGCTTGAAGTGGTCCGGGTGGGGGAAGACGGCGTTGCGGCAC
CTCCGCGCAAGCTGGCCTTGAATGAAGTTTCCCTGATCCGCGCCCAGTCCGGCAAGATGGTGGACCTGGATGCGGAGATA
GACGGAGAATTGCTGAACCGCTACCATGCGGACGGCGTTCTGGTTTCCACCCCCACCGGCTCCACGGCATACTCCCTTTC
CGCCGGGGGGCCTCTGGTCTGGCCCATGTCCCGTGTCGTATGCGTCACCCCCATCTGCCCGCACAGCCTGACCAATCGTT
CCGTGGTGCTTCCTGACAACATGACCATACGCCTGCGGCCCCGCGAGCGCCGCGGCCGCTTTGACTCCATGGTCTATTCC
CTGGACGGCCGTTCCGCCTATCCCATCGAAGTGGGAGAAAGCCTGGTAATCCGGAAGGCGCCGGAAACGCTTTCCCTGGT
TCATCTCCGGAAGCAGAATTTCGGCGCCCTGCTGAGGGCCAAGCTGCGGTGGCAGGGGGCGGAAATCCCCTCGGACGATG
AATAG

Upstream 100 bases:

>100_bases
ACAAAAAAGGAACAAGAGTTGAAATTTAAGGAATAGAGCAGGGCGGAACAATCTTTTCCCGGTTGCGGTTTACCAGTTGA
GTGGCCCGGAAAAATGCAGT

Downstream 100 bases:

>100_bases
GCCGTTGCGGAAGGCCGGCCTCCGGCGGGCTGTCCCCTCACTGTGGAATTCCTGCATCCGGGAACGGTTTCCCATTTATC
GTTCCGCATTGGCGCAGGGG

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MISRMNPSKVIGLVALAEKPGLGEALRIMRRELSRHGLGSCVIETPDALERAIGRCGMLVTFGGDGTMLTVSSLAAMHRV
PLAGVNLGRLGFMTTCSVQELPLLAYALQEGSYLTDERSMLEVVRVGEDGVAAPPRKLALNEVSLIRAQSGKMVDLDAEI
DGELLNRYHADGVLVSTPTGSTAYSLSAGGPLVWPMSRVVCVTPICPHSLTNRSVVLPDNMTIRLRPRERRGRFDSMVYS
LDGRSAYPIEVGESLVIRKAPETLSLVHLRKQNFGALLRAKLRWQGAEIPSDDE

Sequences:

>Translated_294_residues
MISRMNPSKVIGLVALAEKPGLGEALRIMRRELSRHGLGSCVIETPDALERAIGRCGMLVTFGGDGTMLTVSSLAAMHRV
PLAGVNLGRLGFMTTCSVQELPLLAYALQEGSYLTDERSMLEVVRVGEDGVAAPPRKLALNEVSLIRAQSGKMVDLDAEI
DGELLNRYHADGVLVSTPTGSTAYSLSAGGPLVWPMSRVVCVTPICPHSLTNRSVVLPDNMTIRLRPRERRGRFDSMVYS
LDGRSAYPIEVGESLVIRKAPETLSLVHLRKQNFGALLRAKLRWQGAEIPSDDE
>Mature_294_residues
MISRMNPSKVIGLVALAEKPGLGEALRIMRRELSRHGLGSCVIETPDALERAIGRCGMLVTFGGDGTMLTVSSLAAMHRV
PLAGVNLGRLGFMTTCSVQELPLLAYALQEGSYLTDERSMLEVVRVGEDGVAAPPRKLALNEVSLIRAQSGKMVDLDAEI
DGELLNRYHADGVLVSTPTGSTAYSLSAGGPLVWPMSRVVCVTPICPHSLTNRSVVLPDNMTIRLRPRERRGRFDSMVYS
LDGRSAYPIEVGESLVIRKAPETLSLVHLRKQNFGALLRAKLRWQGAEIPSDDE

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=226, Percent_Identity=34.070796460177, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788968, Length=291, Percent_Identity=31.9587628865979, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320794, Length=249, Percent_Identity=32.1285140562249, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=209, Percent_Identity=35.8851674641148, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322509, Length=246, Percent_Identity=32.1138211382114, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28573828, Length=259, Percent_Identity=31.6602316602317, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573832, Length=259, Percent_Identity=31.6602316602317, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161077047, Length=259, Percent_Identity=31.6602316602317, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573830, Length=259, Percent_Identity=31.6602316602317, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573826, Length=259, Percent_Identity=31.6602316602317, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363321, Length=252, Percent_Identity=28.968253968254, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363323, Length=252, Percent_Identity=28.968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653422, Length=252, Percent_Identity=28.968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129957, Length=252, Percent_Identity=28.968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653424, Length=252, Percent_Identity=28.968253968254, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31918; Mature: 31918

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRMNPSKVIGLVALAEKPGLGEALRIMRRELSRHGLGSCVIETPDALERAIGRCGMLV
CCCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCEEE
TFGGDGTMLTVSSLAAMHRVPLAGVNLGRLGFMTTCSVQELPLLAYALQEGSYLTDERSM
EECCCCCEEHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHHH
LEVVRVGEDGVAAPPRKLALNEVSLIRAQSGKMVDLDAEIDGELLNRYHADGVLVSTPTG
HHHHHCCCCCCCCCCHHHHHCHHEEEEECCCCEEEECCCCCHHHHHHHCCCCEEEECCCC
STAYSLSAGGPLVWPMSRVVCVTPICPHSLTNRSVVLPDNMTIRLRPRERRGRFDSMVYS
CCEEEECCCCCEECCCCCEEEECCCCCCCCCCCEEECCCCCEEEECCHHHCCCHHHEEEE
LDGRSAYPIEVGESLVIRKAPETLSLVHLRKQNFGALLRAKLRWQGAEIPSDDE
ECCCEECCCCCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MISRMNPSKVIGLVALAEKPGLGEALRIMRRELSRHGLGSCVIETPDALERAIGRCGMLV
CCCCCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCEEE
TFGGDGTMLTVSSLAAMHRVPLAGVNLGRLGFMTTCSVQELPLLAYALQEGSYLTDERSM
EECCCCCEEHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHHH
LEVVRVGEDGVAAPPRKLALNEVSLIRAQSGKMVDLDAEIDGELLNRYHADGVLVSTPTG
HHHHHCCCCCCCCCCHHHHHCHHEEEEECCCCEEEECCCCCHHHHHHHCCCCEEEECCCC
STAYSLSAGGPLVWPMSRVVCVTPICPHSLTNRSVVLPDNMTIRLRPRERRGRFDSMVYS
CCEEEECCCCCEECCCCCEEEECCCCCCCCCCCEEECCCCCEEEECCHHHCCCHHHEEEE
LDGRSAYPIEVGESLVIRKAPETLSLVHLRKQNFGALLRAKLRWQGAEIPSDDE
ECCCEECCCCCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA