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The map label for this gene is asnC [H]

Identifier: 187735195

GI number: 187735195

Start: 813515

End: 814885

Strand: Reverse

Name: asnC [H]

Synonym: Amuc_0689

Alternate gene names: 187735195

Gene position: 814885-813515 (Counterclockwise)

Preceding gene: 187735196

Following gene: 187735190

Centisome position: 30.59

GC content: 57.84

Gene sequence:

>1371_bases
ATGATGAACAGAACATTGGTGAAACATGTCCTGGACAGTGAGGAGGAAATGCCGGACGTACTGATTCAGGGATGGGTGCG
TACGCGCCGTGATTCCAAGGCTTTTTCCTTTCTGGAGGTGAATGACGGTTCCTCCGTCGCCTCCCTGCAGGTCGTGGCGG
ATGAGGGTATCCCCGGCTATGAACGGATTGGAGAAATGGCTACGGGGTCTGCCGTGAGCATCCGCGGCGCTCTGGTTGCC
GGGCAGGGAAGGCAGCGATGGGAATTGCGCGCCGCTTCCCTGGAGCTGGTGGGGGCTGTTCCGGATTCCTATCCCTTGCA
GAAAAAGGGGCATACGCCGGAGTTTCTGCGTTCCATCGCCCATTTGCGCCCCCGCACCAACCTGTTTGGAGCCGTGTTCC
GCATGCGCAGCAGGCTGGCCTTCGCCATCCACCGCTTTTTCCAGGAAAGGGATTTTTCCTGGGTCAGCACTCCCATTATT
ACCGCCAGTGACTGCGAAGGGGCCGGAGAAATGTTCCGCGTGACGACTTTGGATGTGGGAGACGCTACTTCCCGTGACGC
CTCCCGGGATTTCTTCGGCAAGGCGGCCTACCTCACGGTAAGCGGCCAGCTGGAAGGGGAAGCGTTCGCGTGCGCCCTGA
GCAACATTTATACCTTTGGCCCCACGTTCCGGGCGGAGAACTCCAATACTACGCGCCATGCGGCGGAATTCTGGATGGTG
GAGCCTGAAATGGCATTCTGCGACCTGTATGGAGACATGGACATGGCGGAAGAGTTTGTCCGTTTTCTCGTCGGCGATGC
CTTGGCAAACAGCGCGGAAGAAGTGGAATTCCTGACCCGTTTTGTAGACAAGGGGCTGCGGGAACGCCTGGAGCATGTGA
AGGAAACGCCGTTTGTGCGCTGTTCCTATACGGAAGCCGTGGATATCCTGCTCAAGAGCGGCAAAACATTTGATTACCCC
GTTTCCTGGGGCATCAATCTGCAGAGCGAACATGAACGCTTCCTGACGGAGGAGCATTTTAAATGCCCCGTCATCGTGTA
CAACTACCCGAAGGAGATTAAACCCTTCTATATGCGCCTGAATGAAGACGGAAAGACCGTTACCGCCATGGATGTGCTGG
TGCCCGGCATTGGTGAAATCGTGGGTGGCAGCCAGCGTGAGGAGCGGCTGGATATTCTGGAGGAAAACATGCGCAGCATG
GGCATGAATGCGGAAGCGTACCGGTGGTATGCGGATCTGCGCCGCTACGGCACGGTGCCGCACGCCGGATTCGGTGCCGG
GTTTGAACGCCTGTTGATGTTCGTGACCGGGGTGACCAACATCCGCGACGTCCTGCCTTTTGCCCGTACCCCGCGGAATT
GCGAGTTCTGA

Upstream 100 bases:

>100_bases
GCGGCATATCCCCTCCTTCTCTGCCGGAAAATCCGTAATATTCTCTCCGTGGTGAAGCAATTCTGCTGGCATGGGCAAGG
CGCTGTATTATACTTGCGCC

Downstream 100 bases:

>100_bases
CCTGCTCTGGAAAACGGATTTTTCCGTCTGGAAGGATGCTATATGGTTCCGCAGGATAAATGTTGCGATATAAGGGAGGC
GTGCGCAAACCGGGCCAGCG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MMNRTLVKHVLDSEEEMPDVLIQGWVRTRRDSKAFSFLEVNDGSSVASLQVVADEGIPGYERIGEMATGSAVSIRGALVA
GQGRQRWELRAASLELVGAVPDSYPLQKKGHTPEFLRSIAHLRPRTNLFGAVFRMRSRLAFAIHRFFQERDFSWVSTPII
TASDCEGAGEMFRVTTLDVGDATSRDASRDFFGKAAYLTVSGQLEGEAFACALSNIYTFGPTFRAENSNTTRHAAEFWMV
EPEMAFCDLYGDMDMAEEFVRFLVGDALANSAEEVEFLTRFVDKGLRERLEHVKETPFVRCSYTEAVDILLKSGKTFDYP
VSWGINLQSEHERFLTEEHFKCPVIVYNYPKEIKPFYMRLNEDGKTVTAMDVLVPGIGEIVGGSQREERLDILEENMRSM
GMNAEAYRWYADLRRYGTVPHAGFGAGFERLLMFVTGVTNIRDVLPFARTPRNCEF

Sequences:

>Translated_456_residues
MMNRTLVKHVLDSEEEMPDVLIQGWVRTRRDSKAFSFLEVNDGSSVASLQVVADEGIPGYERIGEMATGSAVSIRGALVA
GQGRQRWELRAASLELVGAVPDSYPLQKKGHTPEFLRSIAHLRPRTNLFGAVFRMRSRLAFAIHRFFQERDFSWVSTPII
TASDCEGAGEMFRVTTLDVGDATSRDASRDFFGKAAYLTVSGQLEGEAFACALSNIYTFGPTFRAENSNTTRHAAEFWMV
EPEMAFCDLYGDMDMAEEFVRFLVGDALANSAEEVEFLTRFVDKGLRERLEHVKETPFVRCSYTEAVDILLKSGKTFDYP
VSWGINLQSEHERFLTEEHFKCPVIVYNYPKEIKPFYMRLNEDGKTVTAMDVLVPGIGEIVGGSQREERLDILEENMRSM
GMNAEAYRWYADLRRYGTVPHAGFGAGFERLLMFVTGVTNIRDVLPFARTPRNCEF
>Mature_456_residues
MMNRTLVKHVLDSEEEMPDVLIQGWVRTRRDSKAFSFLEVNDGSSVASLQVVADEGIPGYERIGEMATGSAVSIRGALVA
GQGRQRWELRAASLELVGAVPDSYPLQKKGHTPEFLRSIAHLRPRTNLFGAVFRMRSRLAFAIHRFFQERDFSWVSTPII
TASDCEGAGEMFRVTTLDVGDATSRDASRDFFGKAAYLTVSGQLEGEAFACALSNIYTFGPTFRAENSNTTRHAAEFWMV
EPEMAFCDLYGDMDMAEEFVRFLVGDALANSAEEVEFLTRFVDKGLRERLEHVKETPFVRCSYTEAVDILLKSGKTFDYP
VSWGINLQSEHERFLTEEHFKCPVIVYNYPKEIKPFYMRLNEDGKTVTAMDVLVPGIGEIVGGSQREERLDILEENMRSM
GMNAEAYRWYADLRRYGTVPHAGFGAGFERLLMFVTGVTNIRDVLPFARTPRNCEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=441, Percent_Identity=45.124716553288, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI4758762, Length=451, Percent_Identity=29.0465631929047, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI45439306, Length=350, Percent_Identity=29.1428571428571, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1787161, Length=448, Percent_Identity=58.7053571428571, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1790571, Length=459, Percent_Identity=24.400871459695, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789256, Length=457, Percent_Identity=21.8818380743982, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788173, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=432, Percent_Identity=33.1018518518519, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=30.1552106430155, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17551876, Length=341, Percent_Identity=27.8592375366569, Blast_Score=111, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=458, Percent_Identity=38.8646288209607, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321807, Length=455, Percent_Identity=28.3516483516484, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=344, Percent_Identity=30.5232558139535, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19922416, Length=461, Percent_Identity=35.5748373101952, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI19921528, Length=445, Percent_Identity=29.2134831460674, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17136276, Length=473, Percent_Identity=27.4841437632135, Blast_Score=108, Evalue=9e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51528; Mature: 51528

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNRTLVKHVLDSEEEMPDVLIQGWVRTRRDSKAFSFLEVNDGSSVASLQVVADEGIPGY
CCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCCCH
ERIGEMATGSAVSIRGALVAGQGRQRWELRAASLELVGAVPDSYPLQKKGHTPEFLRSIA
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHH
HLRPRTNLFGAVFRMRSRLAFAIHRFFQERDFSWVSTPIITASDCEGAGEMFRVTTLDVG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCCEEEEEEEECC
DATSRDASRDFFGKAAYLTVSGQLEGEAFACALSNIYTFGPTFRAENSNTTRHAAEFWMV
CCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCHHHHHHHEEE
EPEMAFCDLYGDMDMAEEFVRFLVGDALANSAEEVEFLTRFVDKGLRERLEHVKETPFVR
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
CSYTEAVDILLKSGKTFDYPVSWGINLQSEHERFLTEEHFKCPVIVYNYPKEIKPFYMRL
EEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEE
NEDGKTVTAMDVLVPGIGEIVGGSQREERLDILEENMRSMGMNAEAYRWYADLRRYGTVP
CCCCCEEEEHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
HAGFGAGFERLLMFVTGVTNIRDVLPFARTPRNCEF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMNRTLVKHVLDSEEEMPDVLIQGWVRTRRDSKAFSFLEVNDGSSVASLQVVADEGIPGY
CCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCCCH
ERIGEMATGSAVSIRGALVAGQGRQRWELRAASLELVGAVPDSYPLQKKGHTPEFLRSIA
HHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHH
HLRPRTNLFGAVFRMRSRLAFAIHRFFQERDFSWVSTPIITASDCEGAGEMFRVTTLDVG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCCEEEEEEEECC
DATSRDASRDFFGKAAYLTVSGQLEGEAFACALSNIYTFGPTFRAENSNTTRHAAEFWMV
CCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCHHHHHHHEEE
EPEMAFCDLYGDMDMAEEFVRFLVGDALANSAEEVEFLTRFVDKGLRERLEHVKETPFVR
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
CSYTEAVDILLKSGKTFDYPVSWGINLQSEHERFLTEEHFKCPVIVYNYPKEIKPFYMRL
EEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEE
NEDGKTVTAMDVLVPGIGEIVGGSQREERLDILEENMRSMGMNAEAYRWYADLRRYGTVP
CCCCCEEEEHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
HAGFGAGFERLLMFVTGVTNIRDVLPFARTPRNCEF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA