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The map label for this gene is uvrA [H]

Identifier: 187735192

GI number: 187735192

Start: 806102

End: 808633

Strand: Direct

Name: uvrA [H]

Synonym: Amuc_0686

Alternate gene names: 187735192

Gene position: 806102-808633 (Clockwise)

Preceding gene: 187735191

Following gene: 187735193

Centisome position: 30.26

GC content: 47.27

Gene sequence:

>2532_bases
ATGAGCCAGTTTTCTAATTTTCAAAGTAGACCGGATCACATTGAAATCCGTGGCGCCCGTGTTCATAATCTGAAAAATAT
TGATTTAGATATCCCGTTGGGCAAGCTGGTAGGAATTACGGGGGTGTCAGGATCAGGAAAGTCCTCTTTGGCTTTGGGCG
TACTTTATGCCGAAGGTTCCCGCCGCTATTTAGAGGCATTGTCCGCCTATACTCGGCGGCGTATAATACAGATGGCAGAG
GCAAAAATTGACAGTATAGAATATGTCCCGGCTGCCCTTGCTCTTCGTCAACGTCCCGCTGTTCCCGGTGTCCGCAGTAC
ATTTGGAACGGCTACCGAACTTTTGAACTCAATCCGGCTTATGTTTTCCCGCTTGGGAAATCACCGCTGTCCCAATGGAC
ATTTGCTTTCGCCATCGGTCAACGTCGCGGCAATGCGTCCCCTTGTCTGCTCTGTATGCGGAGCGGTATTTGACGGTCTC
AGCGCAGAAAGTTTTTCATTCAATGGCCAAGGAGCGTGTCACACCTGCGGAGGAACTGGAATTGTTCAAGCAGTAGACGA
AACAACTTTAGTGCCTGACGAGTCCCTTTCCATTGACGAAGGAGCAGTTGCGCCGTGGAATTCTTTGATGTGGTCGCTGA
TGACTAACGTATGCCGGGCGATGGGCGTTCGAACCGATGTACCTTTTTCGGAGTTGACAGAACAGGAACGGGAGATCGTC
TTTCATGGTCCGCCAGAAAAGAAACATATCCTTTATAAAGCAAAGAGCAGCAATCAAGCGGGAGAAATGGATTTTACCTA
TTATAACGCTGTTTATACCGTGGAAAATGCCCTTGCTAAAGTTAAAGACGAAAAGGGAATGAAGCGGGTAGAAAAATTTT
TGAAGCGGAACGCCTGCCCGAATTGCGGAGGCTCCCGGCTCAATAAGCGGGCGTTATCAAGTCTGCTATGCGGAAAAAAC
CTTGCGGAAATCACCAAAATGACATTAAGCGATTTAACCGCTTGGATAAAGACGATTTCTGCTTCCATGCCGGAAGAACT
AAAAACAATGGCGGAAAGTATCTGCGGTCAATTTCTGCATGTATCAAAACGTCTTTCTGGCTTAGGTCTGGATTATATTA
CCCTTGACCGGGCCGGAACAACGCTTTCCACCGGAGAGCGTCAACGCGTGCAGCTTGCAAGGGCTGTACGAAACCGTACC
ACAGGTGTTCTCTATGTGTTGGATGAACCGTCTATTGGCTTACACCCAGCAAATGTAGATGGGCTGTTGGGCGTTATAGA
TGATCTTATTGCTCATGGTAATTCTGTGATACTGGTAGACCATGATGTGCGAGTTTTAAAGGCTGCTGATTGGTTAATTG
AAATGGGCCCAAAAGCTGGAGAGCATGGCGGACAGATAGTTGCACAGGGAACGATTAAAGCAGTAGCAAAAAAAACGAGT
TCACTCATCGTTGGATTTTTGGCAGACAAGGAAAAACCGGTTATCCGAGAAACGGCAACGCCGGAGGCCATGTTTGCACA
TGGGCATATCAAACTGTCTACTGCTCCTTTGCATACAGTCCATGCCCTTGATTTAGACATCCCCAAAGGTCGGCTGATTG
CTGTAACAGGAGTTTCCGGTTCCGGCAAAACAACACTGATTTTGGAAAGTCTTATTCCCGCCATAGAAGCTGCCATAGCG
AAAGCGCCGATGCCTGACCATGTGAAAAGCGTGGAGGTAGCCGGTATTGAACGTATAAATCTTATTGATGCAACACCTAT
TGGCGTGAATGGCCGTTCTACCGTTGCAACATACAGCGGGATATTAGATGATTTGCGCCGGCTTTATGCAGCTATCCCGG
AAGCAAAATCAAAAGGGTATAAAGTAAGTGACTTTTCCTATAATACTGGGTCACTCCGTTGCTTTGGTTGTGACGGAACA
GGTCAAATTACAATGGATGTGCAATTTCTCCCGGACGTGGATATCATCTGCCCGGACTGCGGCGGCTCCCGCTATGGAAA
AGAAGCGGAGGCAATTCGTTATCGCTCTAAAAAAGACAAGGTGAACGCACCCGGTATTTCTCTGCCTGTACTGATGGGGA
TGACCGTGGAGCAGGCGTTAGAACGCTTATGTGACGTGAAAAAGGTTAAAGAAAAGCTCCAAATTCTTTCTGATTTAGGT
TTGGGTTATTTAACTTTAGGCGAAGCAACTCCTGCCCTGTCCGGCGGTGAGGCACAGCGGCTAAAGCTGGCGGCTGAAAT
GGAAAAGGCACAGGACGACGCCATATTTGTATTTGACGAGCCAACGATTGGACTTCATCCGCTGGATGTACGGATACTAA
TTGGCGTATTTCAGAAACTTGTTGATGCCGGTGCAACAGTTATCGTCATTGAGCATGATTTAAACATGATTGCCAATTCC
GATTATGTGGTCGATATGGGGCCGGGAGGCGGCAAAGCAGGAGGACAAATTGTAGCAACTGGTTTGCCTAAAAAAATCGC
TGAAACGGCTGAAAGCCTTACAGGAAAATATCTATGTGAAATAATTTCATAG

Upstream 100 bases:

>100_bases
GCTTTCATGGTTTTCTGTGAAAGCCCTGTTCTTTTCCAAATATCAAAATCTGGCGATGGGGATGATATAATAAAGTGTAT
AATTAAAAAAAGCGACACTT

Downstream 100 bases:

>100_bases
AAACGTAAATCTGTAGGACGACGGTAAAAGAAAAAGCCGTCGTGCAACAGCATTTTGATACTCCCAAATTAAAAAACGGC
GGTCTCGGGATTCTCAAAGC

Product: ABC transporter

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 843; Mature: 842

Protein sequence:

>843_residues
MSQFSNFQSRPDHIEIRGARVHNLKNIDLDIPLGKLVGITGVSGSGKSSLALGVLYAEGSRRYLEALSAYTRRRIIQMAE
AKIDSIEYVPAALALRQRPAVPGVRSTFGTATELLNSIRLMFSRLGNHRCPNGHLLSPSVNVAAMRPLVCSVCGAVFDGL
SAESFSFNGQGACHTCGGTGIVQAVDETTLVPDESLSIDEGAVAPWNSLMWSLMTNVCRAMGVRTDVPFSELTEQEREIV
FHGPPEKKHILYKAKSSNQAGEMDFTYYNAVYTVENALAKVKDEKGMKRVEKFLKRNACPNCGGSRLNKRALSSLLCGKN
LAEITKMTLSDLTAWIKTISASMPEELKTMAESICGQFLHVSKRLSGLGLDYITLDRAGTTLSTGERQRVQLARAVRNRT
TGVLYVLDEPSIGLHPANVDGLLGVIDDLIAHGNSVILVDHDVRVLKAADWLIEMGPKAGEHGGQIVAQGTIKAVAKKTS
SLIVGFLADKEKPVIRETATPEAMFAHGHIKLSTAPLHTVHALDLDIPKGRLIAVTGVSGSGKTTLILESLIPAIEAAIA
KAPMPDHVKSVEVAGIERINLIDATPIGVNGRSTVATYSGILDDLRRLYAAIPEAKSKGYKVSDFSYNTGSLRCFGCDGT
GQITMDVQFLPDVDIICPDCGGSRYGKEAEAIRYRSKKDKVNAPGISLPVLMGMTVEQALERLCDVKKVKEKLQILSDLG
LGYLTLGEATPALSGGEAQRLKLAAEMEKAQDDAIFVFDEPTIGLHPLDVRILIGVFQKLVDAGATVIVIEHDLNMIANS
DYVVDMGPGGGKAGGQIVATGLPKKIAETAESLTGKYLCEIIS

Sequences:

>Translated_843_residues
MSQFSNFQSRPDHIEIRGARVHNLKNIDLDIPLGKLVGITGVSGSGKSSLALGVLYAEGSRRYLEALSAYTRRRIIQMAE
AKIDSIEYVPAALALRQRPAVPGVRSTFGTATELLNSIRLMFSRLGNHRCPNGHLLSPSVNVAAMRPLVCSVCGAVFDGL
SAESFSFNGQGACHTCGGTGIVQAVDETTLVPDESLSIDEGAVAPWNSLMWSLMTNVCRAMGVRTDVPFSELTEQEREIV
FHGPPEKKHILYKAKSSNQAGEMDFTYYNAVYTVENALAKVKDEKGMKRVEKFLKRNACPNCGGSRLNKRALSSLLCGKN
LAEITKMTLSDLTAWIKTISASMPEELKTMAESICGQFLHVSKRLSGLGLDYITLDRAGTTLSTGERQRVQLARAVRNRT
TGVLYVLDEPSIGLHPANVDGLLGVIDDLIAHGNSVILVDHDVRVLKAADWLIEMGPKAGEHGGQIVAQGTIKAVAKKTS
SLIVGFLADKEKPVIRETATPEAMFAHGHIKLSTAPLHTVHALDLDIPKGRLIAVTGVSGSGKTTLILESLIPAIEAAIA
KAPMPDHVKSVEVAGIERINLIDATPIGVNGRSTVATYSGILDDLRRLYAAIPEAKSKGYKVSDFSYNTGSLRCFGCDGT
GQITMDVQFLPDVDIICPDCGGSRYGKEAEAIRYRSKKDKVNAPGISLPVLMGMTVEQALERLCDVKKVKEKLQILSDLG
LGYLTLGEATPALSGGEAQRLKLAAEMEKAQDDAIFVFDEPTIGLHPLDVRILIGVFQKLVDAGATVIVIEHDLNMIANS
DYVVDMGPGGGKAGGQIVATGLPKKIAETAESLTGKYLCEIIS
>Mature_842_residues
SQFSNFQSRPDHIEIRGARVHNLKNIDLDIPLGKLVGITGVSGSGKSSLALGVLYAEGSRRYLEALSAYTRRRIIQMAEA
KIDSIEYVPAALALRQRPAVPGVRSTFGTATELLNSIRLMFSRLGNHRCPNGHLLSPSVNVAAMRPLVCSVCGAVFDGLS
AESFSFNGQGACHTCGGTGIVQAVDETTLVPDESLSIDEGAVAPWNSLMWSLMTNVCRAMGVRTDVPFSELTEQEREIVF
HGPPEKKHILYKAKSSNQAGEMDFTYYNAVYTVENALAKVKDEKGMKRVEKFLKRNACPNCGGSRLNKRALSSLLCGKNL
AEITKMTLSDLTAWIKTISASMPEELKTMAESICGQFLHVSKRLSGLGLDYITLDRAGTTLSTGERQRVQLARAVRNRTT
GVLYVLDEPSIGLHPANVDGLLGVIDDLIAHGNSVILVDHDVRVLKAADWLIEMGPKAGEHGGQIVAQGTIKAVAKKTSS
LIVGFLADKEKPVIRETATPEAMFAHGHIKLSTAPLHTVHALDLDIPKGRLIAVTGVSGSGKTTLILESLIPAIEAAIAK
APMPDHVKSVEVAGIERINLIDATPIGVNGRSTVATYSGILDDLRRLYAAIPEAKSKGYKVSDFSYNTGSLRCFGCDGTG
QITMDVQFLPDVDIICPDCGGSRYGKEAEAIRYRSKKDKVNAPGISLPVLMGMTVEQALERLCDVKKVKEKLQILSDLGL
GYLTLGEATPALSGGEAQRLKLAAEMEKAQDDAIFVFDEPTIGLHPLDVRILIGVFQKLVDAGATVIVIEHDLNMIANSD
YVVDMGPGGGKAGGQIVATGLPKKIAETAESLTGKYLCEIIS

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=705, Percent_Identity=34.1843971631206, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR013815
- InterPro:   IPR003593
- InterPro:   IPR004602 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 90525; Mature: 90393

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2 ; PS01310 FXYD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFSNFQSRPDHIEIRGARVHNLKNIDLDIPLGKLVGITGVSGSGKSSLALGVLYAEGS
CCCCCCCCCCCCEEEEECCEECCCCCCEEECCHHHHEEEECCCCCCCCCEEEEEEEECCC
RRYLEALSAYTRRRIIQMAEAKIDSIEYVPAALALRQRPAVPGVRSTFGTATELLNSIRL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
MFSRLGNHRCPNGHLLSPSVNVAAMRPLVCSVCGAVFDGLSAESFSFNGQGACHTCGGTG
HHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCC
IVQAVDETTLVPDESLSIDEGAVAPWNSLMWSLMTNVCRAMGVRTDVPFSELTEQEREIV
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEE
FHGPPEKKHILYKAKSSNQAGEMDFTYYNAVYTVENALAKVKDEKGMKRVEKFLKRNACP
EECCCCCCEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NCGGSRLNKRALSSLLCGKNLAEITKMTLSDLTAWIKTISASMPEELKTMAESICGQFLH
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VSKRLSGLGLDYITLDRAGTTLSTGERQRVQLARAVRNRTTGVLYVLDEPSIGLHPANVD
HHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
GLLGVIDDLIAHGNSVILVDHDVRVLKAADWLIEMGPKAGEHGGQIVAQGTIKAVAKKTS
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
SLIVGFLADKEKPVIRETATPEAMFAHGHIKLSTAPLHTVHALDLDIPKGRLIAVTGVSG
HEEEEEECCCCCCCCCCCCCCCCEEECCEEEEECCCCEEEEEEECCCCCCCEEEEEECCC
SGKTTLILESLIPAIEAAIAKAPMPDHVKSVEVAGIERINLIDATPIGVNGRSTVATYSG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCEEEEEEECCCCCCCCCCHHHHHHH
ILDDLRRLYAAIPEAKSKGYKVSDFSYNTGSLRCFGCDGTGQITMDVQFLPDVDIICPDC
HHHHHHHHHHHCCCHHCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCCCEECCCC
GGSRYGKEAEAIRYRSKKDKVNAPGISLPVLMGMTVEQALERLCDVKKVKEKLQILSDLG
CCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LGYLTLGEATPALSGGEAQRLKLAAEMEKAQDDAIFVFDEPTIGLHPLDVRILIGVFQKL
CCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
VDAGATVIVIEHDLNMIANSDYVVDMGPGGGKAGGQIVATGLPKKIAETAESLTGKYLCE
HHCCCEEEEEECCCCEEECCCEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
IIS
HCC
>Mature Secondary Structure 
SQFSNFQSRPDHIEIRGARVHNLKNIDLDIPLGKLVGITGVSGSGKSSLALGVLYAEGS
CCCCCCCCCCCEEEEECCEECCCCCCEEECCHHHHEEEECCCCCCCCCEEEEEEEECCC
RRYLEALSAYTRRRIIQMAEAKIDSIEYVPAALALRQRPAVPGVRSTFGTATELLNSIRL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
MFSRLGNHRCPNGHLLSPSVNVAAMRPLVCSVCGAVFDGLSAESFSFNGQGACHTCGGTG
HHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCC
IVQAVDETTLVPDESLSIDEGAVAPWNSLMWSLMTNVCRAMGVRTDVPFSELTEQEREIV
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEE
FHGPPEKKHILYKAKSSNQAGEMDFTYYNAVYTVENALAKVKDEKGMKRVEKFLKRNACP
EECCCCCCEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NCGGSRLNKRALSSLLCGKNLAEITKMTLSDLTAWIKTISASMPEELKTMAESICGQFLH
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VSKRLSGLGLDYITLDRAGTTLSTGERQRVQLARAVRNRTTGVLYVLDEPSIGLHPANVD
HHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCH
GLLGVIDDLIAHGNSVILVDHDVRVLKAADWLIEMGPKAGEHGGQIVAQGTIKAVAKKTS
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
SLIVGFLADKEKPVIRETATPEAMFAHGHIKLSTAPLHTVHALDLDIPKGRLIAVTGVSG
HEEEEEECCCCCCCCCCCCCCCCEEECCEEEEECCCCEEEEEEECCCCCCCEEEEEECCC
SGKTTLILESLIPAIEAAIAKAPMPDHVKSVEVAGIERINLIDATPIGVNGRSTVATYSG
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCEEECCCEEEEEEECCCCCCCCCCHHHHHHH
ILDDLRRLYAAIPEAKSKGYKVSDFSYNTGSLRCFGCDGTGQITMDVQFLPDVDIICPDC
HHHHHHHHHHHCCCHHCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCCCEECCCC
GGSRYGKEAEAIRYRSKKDKVNAPGISLPVLMGMTVEQALERLCDVKKVKEKLQILSDLG
CCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LGYLTLGEATPALSGGEAQRLKLAAEMEKAQDDAIFVFDEPTIGLHPLDVRILIGVFQKL
CCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
VDAGATVIVIEHDLNMIANSDYVVDMGPGGGKAGGQIVATGLPKKIAETAESLTGKYLCE
HHCCCEEEEEECCCCEEECCCEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
IIS
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8675016 [H]